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3810 results about "Near infra red" patented technology

Method for spectrophotometric blood oxygenation monitoring

A method and apparatus for non-invasively determining the blood oxygen saturation level within a subject's tissue is provided that utilizes a near infrared spectrophotometric (NIRS) sensor capable of transmitting a light signal into the tissue of a subject and sensing the light signal once it has passed through the transmitting a light signal into the subject's tissue, wherein the transmitted light signal includes a first wavelength, a second wavelength, and a third wavelength; (2) sensing a first intensity and a second intensity of the light signal, along the first, second, and third wavelengths after the light signal travels through the subject at a first and second predetermined distance; (3) determining an attenuation of the light signal for each of the first, second, and third wavelengths using the sensed first intensity and sensed second intensity of the first, second, and third wavelengths; (4) determining a difference in attenuation of the light signal between the first wavelength and the second wavelength, and between the first wavelength and the third wavelength; and (5) determining the blood oxygen saturation level within the subject's tissue using the difference in attenuation between the first wavelength and the second wavelength, and the difference in attenuation between the first wavelength and the third wavelength.
Owner:EDWARDS LIFESCIENCES CORP

Multispectral imaging for quantitative contrast of functional and structural features of layers inside optically dense media such as tissue

A method for the evaluation of target media parameters in the visible and near infrared is disclosed. The apparatus comprises a light source, an illuminator/collector, optional illumination wavelength selector, an optional light gating processor, an imager, detected wavelength selector, controller, analyzer and a display unit. The apparatus illuminates an in situ sample of the target media in the visible through near infrared spectral region using multiple wavelengths and gated light. The sample absorbs some of the light while a large portion of the light is diffusely scattered within the sample. Scattering disperses the light in all directions. A fraction of the deeply penetrating scattered light exits the sample and may be detected in an imaging fashion using wavelength selection and an optical imaging system. The method extends the dynamic range of the optical imager by extracting additional information from the detected light that is used to provide reconstructed contrast of smaller concentrations of chromophores. The light detected from tissue contains unique spectral information related to various components of the tissue. Using a reiterative calibration method, the acquired spectra and images are analyzed and displayed in near real time in such a manner as to characterize functional and structural information of the target tissue.
Owner:APOGEE BIODIMENSIONS

Determination of light absorption pathlength in a vertical-beam photometer

Disclosed are photometric methods and devices for determining optical pathlength of liquid samples containing analytes dissolved or suspended in a solvent. The methods and devices rely on determining a relationship between the light absorption properties of the solvent and the optical pathlength of liquid samples containing the solvent. This relationship is used to establish the optical pathlength for samples containing an unknown concentration of analyte but having similar solvent composition. Further disclosed are methods and devices for determining the concentration of analyte in such samples where both the optical pathlength and the concentration of analyte are unknown. The methods and devices rely on separately determining, at different wavelengths of light, light absorption by the solvent and light absorption by the analyte. Light absorption by the analyte, together with the optical pathlength so determined, is used to calculate the concentration of the analyte. Devices for carrying out the methods particularly advantageously include vertical-beam photometers containing samples disposed within the wells of multi-assay plates, wherein the photometer is able to monitor light absorption of each sample at multiple wavelengths, including in the visible or UV-visible region of the spectrum, as well as in the near-infrared region of the electromagnetic spectrum. Novel photometer devices are described which automatically determine the concentration of analytes in such multi-assay plates directly without employing a standard curve.
Owner:MOLECULAR DEVICES

Near-infrared laser scanning confocal imaging system

The invention discloses a near-infrared laser scanning confocal imaging system, which comprises a light path scanning unit and a control unit which adopt a confocal structure, wherein the light path scanning unit comprises a near-infrared laser source, a collimation and extension module, a laser optical filter, a dichroic reflector, a scanning galvanometer, an f-theta lens, a tube lens, an imaging objective lens, a fluorescent optical filter, a convergent lens, a pinhole, a detector and the like, the control unit comprises a motion control module used for controlling the scanning galvanometer, a data acquisition module used for acquiring an output signal of the detector, a data processing module connected with the motion control module and the data acquisition module, and the like. The method matched with the system is characterized in that a sample is marked with near-infrared quantum dots with the fluorescence emission spectrums between 932nm and 1250nm, and then the sample is detected by the near-infrared laser scanning confocal imaging system. According to the system disclosed by the invention, deep-level imaging of samples such as biological tissues can be accurately and efficiently realized, and the system has a simple structure and is easy to operate.
Owner:SUZHOU INST OF NANO TECH & NANO BIONICS CHINESE ACEDEMY OF SCI

Up/down conversion dual-mode fluorescent nanomaterial for Nd<3+> sensitization and synthesis method thereof

The invention belongs to the technical field of nanometer biological materials, and particularly relates to an 800nm excitation-based up/down conversion dual-mode fluorescent nanomaterial for Nd<3+> sensitization and a synthesis method thereof. The synthetic up/down conversion dual-mode fluorescent nanomaterial for Nd<3+>sensitization designed by the invention has a multi-layer core-shell structure, and comprises a down conversion luminous layer, an up conversion luminous layer, an isolation layer and a passivation layer. Different layers of the material synergistically play respective different roles, and meanwhile, the dual-mode fluorescent probe with up conversion fluorescence and down conversion fluorescence is finally achieved under an 800nm of excitation light with a low-heat effect. The up conversion excitation light is expanded to about 800nm from 980nm by Nd<3+>, Yb<3+> and Er<3+>-doped NaGdF4:Nd, Yb, Er up conversion layer due to introduction of Nd<3+>, and the fluorescent process from a near infrared light to a visible light is achieved. The process meets the requirements of an in-vitro fluorescent probe. In addition, the typical down conversion fluorescence from the near infrared light to a far infrared light is also achieved in one nanoparticle due to the synergistic effect of the NaGdF4:Nd core.
Owner:FUDAN UNIV

Method for diagnosing crop water deficit through hyperspectral image technology

The invention relates to a method for diagnosing the crop water deficit through a hyperspectral image technology, and especially relates to a method for diagnosing the Lycopersicon esculentum Mill. leaf area water based on hyperspectral images. The method comprises the following steps: 1, acquiring Lycopersicon esculentum Mill. leaf hyperspectral image data through a self-constructed hyperspectral imaging system; 2, selecting a characteristic wavelength by optimizing through an adaptive band selection process to realize multidimensional datum dimensionality reduction; 3, dividing the image ofeach sample at the characteristic wave, counter-rotating, carrying out form operation to obtain a target image, and extracting the leaf gray level and the leaf texture characteristic from the target image; and 4, selecting an optimal characteristic subclass through a GA-PLS (genetic algorithm-partial least square) process by fusing the gray scale and the texture characteristic and aiming at ten characteristic variables, and establishing a partial least square regression model based on the optimal characteristic, wherein the correlation coefficient R between a predicted value and a measured value of the model is 0.902. Compared with routine detection methods, the method of the invention has the advantages of rapid detection speed, and simple and convenient operation; and compared with a single near infrared spectroscopy or computer vision technical means, the method of the invention allows obtained information to be comprehensive, and the accuracy and the stability of the detection result to be improved.
Owner:JIANGSU UNIV
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