11 results about "Intracranial pressure" patented technology

The invention discloses a multifunctional neural electrode for intracranial pressure detection and closed-loop nerve regulation, the multifunctional electrode sequentially comprises a PMUT electrode for intracranial pressure detection and nerve regulation and a macro-micro electrode for electroencephalogram signal detection from top to bottom, and the PMUT electrode is bonded on the macro-micro electrode. The PMUT electrode is bonded to the macro-micro electrode to serve as a multifunctional electrode, the PMUT electrode can serve as a pressure sensor and can also serve as an ultrasonic transducer, the dual functions of intracranial pressure detection and fixed-point ultrasonic nerve stimulation are achieved, the macro-micro electrode can achieve detection of local field potential and peak potential, and the ultrasonic nerve stimulation function is achieved. Therefore, a detection-feedback-regulation closed-loop system is realized.

The invention discloses an intracranial pressure sensor connecting method and device, and belongs to the technical field of medical instruments. The method comprises the following steps that a nylon pipe is pre-fixed in a shell hole, specifically, the nylon pipe penetrates through a round hole in a shell from top to bottom and then penetrates through a square hole from bottom to top to achieve pre-fixing; the varnished wire is welded to the PCB bonding pad, a certain length of the varnished wire is reserved, the tail end of the varnished wire is tinned, and the tinned varnished wire is welded to the tinned PCB bonding pad; and reinforcing the connection part of the nylon tube and the enamelled wire by using glue, namely applying glue to a bottom glue area of the PCB to fix the nylon tube, bending the reserved enamelled wire and fixing the enamelled wire in an enamelled wire glue coating area, and applying glue to a bonding pad glue area to reinforce the connection point of the bonding pad and the enamelled wire. According to the connecting method and device, the technical problem of unstable enameled wire connection in the intracranial pressure sensor is solved, the connecting reliability is improved, and the service life of a product is prolonged.

A method and system for estimating intracranial pressure using a regression model. Optical interferometric measurements related to cerebral blood flow are generated. Intracranial pressure is estimated using a regression model based on optical interferometry and a characteristic of extracerebral blood flow or extracerebral blood pressure.

A method and system for estimating intracranial pressure using a regression model. Optical interferometric measurements of cerebral blood flow are generated. Intracranial pressure is estimated using a regression model based on the optical interferometric measurements and one feature of extracerebral blood flow or extracerebral blood pressure.

The invention discloses a multi-time temperature compensation method, system and equipment for an intracranial pressure sensor, and relates to the technical field of sensors. The method comprises the following steps: controlling a plurality of preset temperature points through an incubator, and determining the plurality of temperature points as a temperature set; in the state of the target temperature point, obtaining a target temperature ADC value according to each temperature ADC value obtained at each preset moment, and obtaining pressure ADC values under a plurality of pressure points corresponding to the target temperature ADC value; performing calculation according to the pressure ADC values under the plurality of pressure points to obtain corresponding zero offset values and pressure sensitivity; obtaining each zero offset value and each pressure sensitivity corresponding to the temperature set; and substituting the temperature set, and each zero offset value and each pressure sensitivity corresponding to the temperature set into a preset fitting model to obtain a final fitting coefficient value, and importing the final fitting coefficient value into a target memory to output a compensation parameter. According to the method and the device, a dynamic scheme that cubic fitting is preferential and quadratic fitting is automatically switched is adopted, so that over-fitting is effectively avoided, and the adaptability of temperature compensation is improved.

The present invention provides a method for reconstructing transcranial images using a dual-mode ultrasound phased array probe. The method includes the steps of: controlling multiple channels to irradiate energy onto an intracranial target point in a patient; receiving backscattered energy reflected from the intracranial target point through the multiple channels to generate backscattered radio frequency data for each; and reconstructing an acoustic distribution image in real time based on the backscattered radio frequency data. Compared to pre-treatment ray tracing, the present invention can display intracranial pressure distribution in real time; compared to magnetic resonance thermometry, it can be applied to low-energy applications without temperature changes; and compared to passive cavitation imaging, it can stably present acoustic distribution images without relying on microbubbles.

A medical system and a liquid circulation system, which are capable of efficiently delivering the liquid to the treatment area of the brain while suppressing the fluctuations in the intracranial pressure. The medical system includes a control unit that executes control of setting a first period in which the liquid is injected into the body cavity and the liquid is not discharged from the body cavity and a second period in which the liquid is not injected into the body cavity and the liquid is discharged from the body cavity, and alternately repeating the first period and the second period to set an injection amount of the liquid in the first period to be substantially the same as a discharge amount of the liquid in the second period.

Disclosed herein are compositions of biodegradable scaffolds combined with mesenchymal stem cells and methods of use thereof for the regeneration of cranial sutures and treatment of craniosynostosis, which can help reverse increased intracranial pressure and skull and neurocognitive abnormalities.

The application discloses a kind of risk stratification model construction method and system for EGFR mutant non-small cell lung cancer meningeal metastasis patient, belong to tumor prognosis evaluation technical field.The multicenter retrospective clinical database is first constructed and data preprocessing is completed, then the predictor is screened by LASSO Cox regression, and the five core prognostic factors of ECOG PS score, brain metastasis, MRI meningeal enhancement, CSFC result and intracranial pressure are determined by multi-factor Cox proportional risk regression and linear predictor is constructed, then it is converted into integer type weighted risk score, finally the best cutoff value is determined based on survival function, and the patient is divided into low-risk group and high-risk group.The application can clearly distinguish the patient group with significant difference in prognosis, the required indicators are all clinical routine items, the operation is simple, the accessibility is high, can accurately guide individualized treatment decision and clinical trial stratification, and has important clinical application value.

The implanted pressure sensors can non-invasively and stably measure intracranial pressure using MRI-compatible materials. In some examples, the implanted pressure sensor can include a fluid reservoir filled with a fluid. The sensor may also include a gas chamber filled with a gas and a gas-fluid interface. The interface may include a channel. The channel may have a first end and a second end. The channel may have a pattern that includes a plurality of linear segments connected by a plurality of junction segments. The fluid reservoir may be in flow communication with the gas-fluid interface. The gas chamber may be in flow communication with the gas-fluid interface and spaced separate from the gas-fluid interface.

The invention provides a self-adaptive brain pressure self-adjusting artificial skull. The self-adaptive brain pressure self-adjusting artificial skull comprises a plurality of artificial skull flaps and a fixing device, the artificial skull flaps are made of materials compatible with body tissues, and the multiple artificial skull flaps can be installed together to form an overlapping structure with a circular coverage area. The size of an overlapping area of the overlapping structure can be adjusted according to the change of the intracranial pressure; the fixing device can fix the artificial skull flaps on the skull body. The artificial skull can be implanted immediately during an operation, the decompression effect is not affected after the skull is implanted, the artificial skull has the self-adaptive craniocerebral pressure, the craniocerebral space of an operation area is automatically adjusted, and meanwhile trauma and risks caused by skull repairing through a secondary operation are avoided.