55 results about "Choroid" patented technology

The invention provides a dynamic myopia management lens prescription customization method and system, and relates to the technical field of lens design and customization. According to the dynamic myopia management lens prescription customization technology provided by the invention, ophthalmic basic data of a patient is acquired; then periodically follow-up the patient to obtain ophthalmology measurement follow-up data of the patient; the joint evaluation model dynamically updates a myopia risk evaluation grade of the patient based on ophthalmology basic data and ophthalmology measurement follow-up visit data; and finally, dynamically updating the lens prescription based on the myopia risk assessment level of each time by the joint assessment model. According to the technical scheme, the combined evaluation model can perform dynamic lens prescription adjustment according to follow-up visit ocular axis progress and choroid change conditions, dynamic myopia management lens prescription customization, whole-course tracking of a myopia cycle and individualized prevention and control management are realized, and thus the effectiveness and continuity of myopia prevention and control are improved.

The invention discloses an idiopathic macular pore patient postoperative retina change clinical observation method, which comprises the following steps: S1, collecting patient data, S2, carrying out an operation, S3, carrying out statistical analysis, S4, comparing data, and S5, concluding, and collecting 32 idiopathic macular pore patients to be included in the group for research. All patients are divided into two groups according to different operation modes, main observation indexes are central retina light sensitivity and peripheral retina light sensitivity, and other observation indexes comprise optimal corrected vision, retina superficial layer blood flow density, retina deep layer blood flow density and macular central depressed choroid thickness. The differences of the observation indexes between the two groups are compared, it is obtained through observation that after the idiopathic macular hole is treated through the vitreous body operation, the retina light sensitivity of the center of the macular part is obviously improved in the early stage of the operation, and improvement of the retina light sensitivity of the center of the macular part is closely related to changes of the retina blood flow density.

An apparatus for delivering therapeutic agent to an eye comprises a body, a cannula, a hollow needle, and an actuation assembly. The cannula extends distally from the body and is sized and configured to be insertable between a choroid and a sclera of a patient's eye. The actuation assembly is operable to actuate the needle relative to the cannula to thereby drive a distal portion of the needle along an exit axis that is obliquely oriented relative to the longitudinal axis of the cannula. The cannula may be inserted through a sclerotomy incision to position a distal end of the cannula at a posterior region of the eye, between the choroid and sclera. The needle may be advanced through the choroid to deliver the therapeutic agent adjacent to the potential space between the neurosensory retina and the retinal pigment epithelium layer, adjacent to the area of geographic atrophy.

An intraocular implant, kit, and method are disclosed. In one configuration, the implant is a frame that is installable in the suprachoroidal space of the eye and has an arcuate elongated shape that promotes the drainage of aqueous humor through the suprachoroidal space when installed in the suprachoroidal space and is configured to take on an elastically recoverable shape. The frame has a first axial end and a second axial end with respect to the longitudinal axis of the elongated shape, and the arcuate elongated shape defines a channel. The channel has a first axial opening at the first axial end of the frame, a second axial opening at the second axial end of the frame, and a longitudinal opening that extends continuously from the first axial end to the second axial end of the frame.

The present application relates to the field of traditional Chinese medicine, in particular to a kind of traditional Chinese medicine composition for treating central serous chorioretinopathy and application thereof.The present application provides a kind of traditional Chinese medicine composition for treating central serous chorioretinopathy, compared with the prescription of Chunzai Decoction, the traditional Chinese medicine composition of the present application increases the efficacy of promoting blood circulation and removing blood stasis, soothing the liver and relieving depression, clearing the liver and improving eyesight, clearing heat and reducing phlegm on the basis of Chunzai Decoction warming yang, transforming qi, reducing water and removing dampness;Compared with using Chunzai Decoction alone, the curative effect of patients using the traditional Chinese medicine composition is more direct, from 2-3 weeks to 1 week, and the curative effect is accelerated.And the traditional Chinese medicine composition of the present application has been used for about 2 years, 2 / 3 of the 112 patients can see effect in 1 week, and no recurrence is found within 3 months.

The invention discloses an eye movement guiding device for eye muscle exercise and a using method thereof, and relates to the technical field of vision health care instruments, the eye movement guiding device comprises a shell, a multi-dimensional adjusting mechanism and a sighting mark; the multi-dimensional adjusting mechanism is arranged in the shell, the sighting mark is arranged on the multi-dimensional adjusting mechanism, and the multi-dimensional adjusting mechanism drives the sighting mark to move in the shell; wherein the multi-dimensional adjusting mechanism comprises an X-axis track, a Y-axis track and a Z-axis track; the Y-axis track is arranged in the shell; the X-axis track is arranged on the Y-axis track, and the Y-axis track is used for driving the X-axis track to slide; the Z-axis track is arranged on the X-axis track, and the X-axis track is used for driving the Z-axis track to slide; the sighting mark is arranged on the Z-axis track, the Z-axis track is used for driving the sighting mark to slide, the eyeballs can rotate along with the sighting mark, ciliary muscles, six extraocular muscles and a choroidal system are synchronously activated, the extraocular muscles improve coordination and glancing ability in three-dimensional track movement, and plane fixation stiffness of short-distance eye use is broken.

The present invention relates to compounds useful for treating diseases or conditions associated with excessive vascularization of the eye, such as corneal neovascularization, iris neovascularization, ciliary body neovascularization, corneal pannus, choroidal neovascularization, retinal neovascularization, wet age-related macular degeneration, proliferative diabetic retinopathy, retinopathy of prematurity, and ischemic retinopathy.

The invention relates to a saffron crocus eye pad and a method for controlling eye axis growth, and belongs to the technical field of eye care products. The eye patch comprises a patch carrier and a plant extraction gel layer coated on the patch carrier, the plant extract gel layer is composed of mulberry leaf extract, chrysanthemum extract, butterflybush flower extract, amur corktree extract, crocus sativus flower extract, lithospermum extract, madder extract, lycium ruthenicum extract, beet root juice powder, natural borneol, menthol, xanthan gum, purified water and other natural components. The crocus sativus flower extract can enhance the blood flow speed of choroid, thicken the choroid and effectively control the growth of an ocular axis, so that the effect of delaying or improving the development of myopia is achieved. According to the gel layer, a hydrogel structure is formed through xanthan gum, natural borneol and menthol are combined to provide cooling and soothing effects, and the gel layer has good skin affinity and use safety.

An ocular access instrument (20) includes an attachment assembly (32) configured to engage a sclera of an eye, and an actuator assembly (34) configured to bear against the sclera. When the attachment assembly engages the sclera, movement of the actuator assembly inwardly against the eye displaces the choroid from the sclera, thereby creating an enlarged suprachoroidal space. The ocular access instrument may also include a needle guide (40) configured to receive the needle and guide the needle into the enlarged suprachoroidal space.

The invention discloses a pathological myopic lesion classification method, system and device and a medium, belongs to myopic lesion classification in artificial intelligence medicine, and aims to solve the technical problem that choroidal lesion classification accuracy is low due to the fact that diagnosis complexity cannot be captured when multiple pathological myopic lesions exist at the same time are classified in the prior art. The method comprises the following steps: acquiring an OCT sample image and a label, constructing and training a myopic lesion classification model, and performing real-time classification; the myopia lesion classification model comprises a shared encoder, a segmentation decoder and a classification decoder; the shared encoder comprises four residual blocks which are arranged in sequence; the segmentation decoder is a semi-supervised divider; the classification decoder comprises a focus focusing module, a pyramid structure feature fusion module and a classification module which are arranged in sequence. A myopia lesion classification model is creatively constructed, a segmentation decoder can automatically identify a choroid structure in an OCT image, and the blank between a traditional clinical index and a deep learning diagnosis system is effectively filled.

The invention relates to the technical field of lighting equipment, in particular to a negative oxygen ion eye-protection lamp capable of inhibiting myopia and relieving asthenopia, which comprises an eye-protection lamp body, a lamp post and a negative oxygen ion generator, the eye-protection lamp body is used for emitting full-spectrum light; the negative oxygen ion generator is installed at the joint of the eye protection lamp body and the lamp pole, and the concentration of negative oxygen ions generated by the negative oxygen ion generator is 5000-5000 / cm < 3 >. When the eye protection lamp is used, the negative oxygen ion generator is arranged at the joint of the eye protection lamp body and the lamp pole, the negative oxygen ion generator can generate negative oxygen ions with the concentration of 5000-50000 / cm < 3 >, more dopamine is secreted by a living body through the negative oxygen ions, the fundus blood flow density and the fundus retina cell activity are improved, the choroid thickness is increased, and therefore the eye protection effect is improved. Therefore, the visual comfort is improved, and the effects of inhibiting myopia and relieving asthenopia are achieved.

The invention discloses a retinal vessel three-dimensional imaging system and method based on an ultra-wide-angle laser fundus camera, and relates to the field of medical imaging devices. The problems that layered imaging cannot be achieved through single-wavelength laser in existing fundus imaging, and the scanning angle of an existing dual-wavelength confocal system is limited are solved. The system comprises a multi-wavelength laser generating unit, a semi-transmitting and semi-reflecting element, a galvanometer unit, a chromatic aberration lens, a sample to be detected, a focusing lens and a detector with a pinhole, laser emitted by the multi-wavelength laser generating unit is reflected by the semi-transparent and semi-reflective element, then sequentially passes through the galvanometer unit and the chromatic aberration lens, is emitted to a to-be-detected sample, sequentially passes through the chromatic aberration lens, the galvanometer unit, the semi-transparent and semi-reflective element and the focusing lens after being reflected by the to-be-detected sample, is received by the detector with a pinhole, and reaches the silicon PM; a multi-wavelength retina confocal image is generated from the signals acquired by the silicon PM. The method is also suitable for the field of full-layer three-dimensional imaging from the retina nerve fiber layer to the choroid.

The present application relates to the field of ophthalmic medical technology, especially to an eyeball cornea treatment system based on near-infrared light recognition, which acquires optical information of eyeball cornea and choroid by collecting near-infrared light signals, and performs digitalization and filtering processing on the original image to output processed image data. Combining edge detection and threshold segmentation, choroid defects or atrophic lesion points are identified, and corneal thickness and curvature are measured to determine the energy intensity, irradiation time, wavelength and focusing position of the excimer light beam. According to the parameters, an excimer light beam with a wavelength of 248 nanometers is emitted to irradiate and treat the lesion area, which improves the positioning accuracy of the lesion while avoiding damage to normal tissue structures, and meets the safety and effectiveness requirements of eye treatment.

The invention provides an experimental animal eyeball extraction mark fixing and choroid paving piece positioning device which comprises an annular adjustable ferrule assembly and a square positioning ferrule assembly, the annular adjustable ferrule assembly and the square positioning ferrule assembly are of detachable structures, and the annular adjustable ferrule assembly is connected to the upper surface of the square positioning ferrule assembly in a clamped mode; the annular adjustable ferrule assembly is an annular main body and comprises an adjustable inner ring, the inner diameter of the adjustable inner ring can be elastically adjusted to adapt to eyeballs of different sizes, the technical field of ophthalmology basic experimental animal research equipment is involved, and the inner diameter of the adjustable inner ring of the annular adjustable ferrule assembly can be elastically adjusted to adapt to experimental rodent eyeballs of different sizes. The eyeball marking and taking-out device has the advantages that small eyeballs of young rats and large eyeballs of adult rats can be tightly attached to each other, accordingly, the stability of the eyeballs in marking and taking-out procedures can be guaranteed, eyeball injuries due to improper matching of the ferrules and the eyeballs can be prevented, the application range of the eyeball marking and taking-out device can be expanded, and the universality and the practicability of the eyeball marking and taking-out device can be improved.

An apparatus and method for aiding in the detection of dementia, concussion, other neurologic conditions, retinal, and optic nerve conditions. The apparatus enables the diffusion coefficient of the tissue to be ascertained and studied by directing the light from a laser or other coherent light source at the patient's retina, optic nerve or choroid and measuring the fluctuations in the intensity of the back-scattered light caused by the movement of light scatterers in the tissue. By comparing the measurements to a normal database, or to the subject's previous measurement, in combination with an eye examination and OCT image / measurement the changes caused by the disease and the effectiveness of therapy can be ascertained. The disclosed apparatus allows the incident and detection optics to be attached to ophthalmic devices typically used in ophthalmologic care. Also, where both the incident laser fiber optic and the detection fiber optic are directly connected to goggles, one or more or all of the above-described mirrors may not be necessary, as both fiber optics are preferably directly directed into the eye.

The utility model relates to an organ model which comprises a model body with an inner cavity, a plurality of red venation bodies and a plurality of purple venation bodies for simulating blood capillaries are arranged in the side wall of the model body, and the red venation bodies and the purple venation bodies are located on the side close to the inner surface of the model body. The red venation body and the purple venation body are arranged on the inner surface of the model body, so that the red venation body and the purple venation body are visible from the inner surface of the model body, a plurality of surface venation bodies for simulating coarse vessels are arranged on the inner surface of the model body, and a transparent adhesive layer for simulating mucous membranes is arranged on the inner surface of the model body. The surface vein body is located between the transparent adhesive layer and the inner surface of the model body. The structure and the color level of the blood vessel on the organ model are more consistent with the reality, so that the evaluation test of the image is more in line with the clinical requirements, the manufacturing is simple, the storage is convenient, the test cost can be reduced, the reutilization can be realized, the resource waste is avoided, and the continuity and the result stability of the evaluation test are good.

Systems, methods and software for scanning an ocular structure of an eye are provided. A method includes projecting a light onto the ocular structure, and scanning, by natural movements of the living eye, the light in a region of the living eye. Applicable ocular structures can include an ocular surface, a cornea, a sclera, an iris, a crystalline lens, an ocular fundus, a retina, a choroid, and a vitreous humor. A system includes a light source to create light, and optics to focus the light from the light source onto the ocular structure and to collect secondary light coming from the eye towards a detector. The system also includes a tracking system to register positions of the eye at different times, and a computer system to receive signals coupled from the tracking system representative of eye positions at different times and associate the signals with the tracking position.

An apparatus for delivering therapeutic agent to an eye comprises a body, a cannula, a hollow needle, and an actuation assembly. The cannula extends distally from the body and is sized and configured to be insertable between a choroid and a sclera of a patient's eye. The actuation assembly is operable to actuate the needle relative to the cannula to thereby drive a distal portion of the needle along an exit axis that is obliquely oriented relative to the longitudinal axis of the cannula. The cannula may be inserted through a sclerotomy incision to position a distal end of the cannula at a posterior region of the eye, between the choroid and sclera. The needle may be advanced through the choroid to deliver the therapeutic agent adjacent to the potential space between the neurosensory retina and the retinal pigment epithelium layer, adjacent to the area of geographic atrophy.

The utility model provides a display device and a learning tablet, the display device comprises a display screen and an eye protection illumination module, the eye protection illumination module comprises a preset eye protection light source, and the eye protection illumination module is arranged in a reciprocating sliding mode relative to the display screen so as to be stored behind the display screen or extend out of the display screen area; and after extending out of the display screen area, the light source is started to irradiate human eyes. According to the application, the eye protection illumination module independent of the display screen is utilized to irradiate the human eyes, through the non-invasive photobiological regulation effect, the choroid thickness and the retinal metabolism are enhanced, the asthenopia is relieved, meanwhile, myopia development is inhibited from the source, and the incidence rate of myopia is effectively reduced.

An ocular implant system is described herein in which an implant (200) is deployed in the posterior space of an eye - e.g., the suprachoroidal space or the subconjunctival space or the intrascleral space - through an access in the anterior chamber (160) for reducing intraocular pressure in the eye. The shunt device (200) is implanted using an implantation device that includes a hollow shaft (330) mounted on a fixed shaft (320). The shunt device (200) is located in the distal end of the hollow shaft (330) and adjacent to the distal end of the fixed shaft (320) at a location behind the distal end of the hollow shaft. Once the distal end of the hollow shaft (330) and the shunt device (200) are at the desired depth within the posterior space, the hollow shaft is withdrawn over the fixed shaft through the access in the anterior chamber (160) towards the proximal end of the fixed shaft, leaving the shunt device in the posterior space.

A stent implant for treating glaucoma by intraocular fluid drainage from the anterior chamber, for example into the suprachoroidal space. The stent implant is designed to change in shape after being inserted into the eye, during which change the width and / or thickness or the flow cross-section is increased by for example 20%, in another example more than 200%, and in a further example by more than 400%, at least one point of the stent implant. In the case of intraocular fluid drainage from the anterior chamber into the suprachoroidal space, a cyclodialysis cleft which may open can be largely or completely closed. With appropriate adjustments, the stent implant can also be applied in trabecular, uveoscleral, uveolymphatic and subconjunctival applications for intraocular fluid drainage from the anterior chamber. The implant can even be used for direct intraocular fluid discharge from the anterior chamber onto the surface of the eye.

The present disclosure relates to a medicine depth delivery device, which comprises a delivery part with a containing structure for containing a medicine, a needle connected with the containing structure, and a positioning part sleeved on the needle, the positioning part having a positioning structure and a scale arranged at the bottom end thereof, the positioning structure comprising a first positioning structure and a second positioning structure, the first positioning structure and the second positioning structure being flipped towards the radial outside of the body relative to the body, the first positioning structure having a first opening with the body, the second positioning structure having a second opening with the body, and the opening directions of the first opening and the second opening being opposite to each other. By being provided with the positioning structure and the positioning part with the scale, the positioning part can be fixed to the desired position in the case of delivering the medicine to the choroid and scleral space, and the effect of high-precision depth delivery is achieved in combination with the previously measured scleral thickness.

The present invention relates to an apparatus (110) and a method (210) configured determining a choroidal topography (218) over a region (114, 114') on a retina (116) of an eye (117) of a person as well as to a use of the apparatus (110) for determining an effect of at least one ophthalmic lens design on the choroidal topography (218). Herein, the apparatus (110) comprises: - at least two individual displays (122, 122') each configured for providing a retinal stimulus (112, 112'), thereby providing two independent retinal stimuli (112, 112'); - at least two optical transfer elements, comprising a first optical transfer element and a second optical transfer element, each configured for projecting at least one of the retinal stimulus (112, 112') or a phase map to a region on a retina of an eye of a person, wherein the phase map comprises a modified retinal stimulus; - a measuring device (142) for capturing a choroidal topography (218) over the region (114, 114') on the retina (116) of the eye (117) of the person by using reflected light received from the region (114, 114') on the retina (116) of the eye (117) of the person; - an optical filter (152) configured for separating the reflected light received from the region (114, 114') on the retina (116) of the eye (117) of the person from the phase map projected to the region (114, 114') on the retina of the eye of the person, wherein the second optical transfer element is further configured for simultaneously projecting each of the at least two individual phase maps at a different retinal eccentricity to each of at least two separate regions (134, 134') on the retina (116) of the eye (117) of the person, wherein the separate regions (134, 134') comprise a peripheral region and a foveal region on the retina (116) of the eye (117) of the person.

Provided are formulations and methods for treating patients having AMD, by inhibiting formation or growth of drusen, and / or reducing number and / or size of drusen, while maintaining or restoring ellipsoid zone area in a human eye.

The invention discloses a red-light small-hole optical lens for preventing and controlling axial myopia and a manufacturing method of the red-light small-hole optical lens. Relates to the technical field of optical lenses, and comprises a lens base body and a plurality of optical functional areas arranged on the lens base body, each functional area has different light transmittances for 620-650 nm red light, and the light transmittances are gradually distributed from the center of the optical functional area to the edge of the optical functional area by 10%-99.99%. The optical function area comprises but is not limited to a three-area or four-area structure, and a red dot diffusion effect from deep to light is formed through cooperation of the light transmittance of all the areas. Red light with a specific wavelength can be projected to retina and choroid areas in a dispersion manner, and choroid blood circulation is improved through a photobiological effect, so that the growth of an ocular axis is inhibited. And the optical functional area is manufactured through a process of combining red light pulse laser internal micro-engraving or ultraviolet laser surface etching with high-transmittance red light film layer lamination. Red light treatment and daily glasses are combined, and all-weather and living myopia prevention and control are achieved.

The invention relates to an eye essence stock solution and a preparation method thereof. The eye essence stock solution comprises a traditional Chinese medicine compound extraction concentrated solution. The traditional Chinese medicine compound comprises ligusticum wallichii, liquorice, fructus lycii, salvia miltiorrhiza, nacre mother of pearl, caulis spatholobi, angelica sinensis, pseudo-ginseng, cornu cervi pantotrichum, crocus sativus, semen cassiae and selaginella tamariscina. According to the essence stock solution, through the synergistic interaction of all the components in the traditional Chinese medicine compound, the essence stock solution penetrates through skin to directly reach fundus, clears and activates channels and collaterals, warms channels and dispels cold, promotes blood circulation of eyes, effectively improves nutrition of tissues around the eyes, relaxes ciliary muscles which are tense and shrunk for a long time, and enables choroids to be hyperemia and thickened so as to play a role in regulating and controlling myopia.

The present invention provides devices to access the suprachoroidal space or sub-retinal space in an eye via a minimally invasive transconjunctival approach. The devices may also be used after a partial dissection, for example after dissection of the outer scleral layer of the eye, and using the device within the dissection to access the suprachoroidal space or the sub-retinal space.

There is provided an implant configured to be deployed in an eye by a deployer tool to facilitate conduction of fluid from a posterior chamber to a suprachoroidal space of the eye, the implant comprising, an elongate member having a proximal segment configured to be disposed in the posterior chamber of the eye and a distal segment configured to be disposed in the suprachoroidal space of the eye, wherein the elongate member is configured to maintain a bent configuration that substantially complies with anatomical curvatures of the posterior chamber and the suprachoroidal space, when deployed in the eye. There is also provided a deployer tool for inserting an implant as disclosed herein into an eye to facilitate conduction of fluid from a posterior chamber to a suprachoroidal space of the eye, and a system for facilitating the conduction of fluid from a posterior chamber to a suprachoroidal space of an eye.