71 results about "Choroid" patented technology

Devices and methods for treating intraocular pressure are disclosed. The devices include shunts for draining aqueous humor from the anterior chamber to the uveoscleral outflow pathway, including the supraciliary space and the suprachoroidal space. The shunts are preferably implanted by ab interno procedures.

The invention provides a dynamic myopia management lens prescription customization method and system, and relates to the technical field of lens design and customization. According to the dynamic myopia management lens prescription customization technology provided by the invention, ophthalmic basic data of a patient is acquired; then periodically follow-up the patient to obtain ophthalmology measurement follow-up data of the patient; the joint evaluation model dynamically updates a myopia risk evaluation grade of the patient based on ophthalmology basic data and ophthalmology measurement follow-up visit data; and finally, dynamically updating the lens prescription based on the myopia risk assessment level of each time by the joint assessment model. According to the technical scheme, the combined evaluation model can perform dynamic lens prescription adjustment according to follow-up visit ocular axis progress and choroid change conditions, dynamic myopia management lens prescription customization, whole-course tracking of a myopia cycle and individualized prevention and control management are realized, and thus the effectiveness and continuity of myopia prevention and control are improved.

The invention belongs to the technical field of glasses, and discloses a pair of out-of-focus glasses for treating hyperopia, which comprises hyperopia out-of-focus glasses lenses, the hyperopia out-of-focus glasses lenses are convex lenses, a central vision far optical area is arranged at the circle center of each convex lens, hyperopia out-of-focus micro lenses are uniformly distributed on the periphery of each central vision far optical area, and the micro lenses are arranged in the central vision far optical area. Peripheral micro-concave lenses are added on the basis of previous hyperopia glasses, so that an object image forms hyperopia defocus on peripheral retina, after the peripheral retina recognizes a hyperopia defocus signal, in order to form a clear object image on the retina, eyeballs can start a sclera and choroid compensation mechanism by the brain, abnormal growth of the eyeballs is caused, and the hyperopia defocus effect is improved. And the speed of reducing the hyperopia degree is further increased.

The present invention provides an implant configured to be deployed in an eye by a deployment tool to facilitate conduction of fluid from a posterior chamber of the eye to a suprachoroidal space, the implant comprising an elongate member, and an elongate member having a proximal section configured to be disposed in the posterior chamber of the eye and a distal section configured to be disposed in the suprachoroidal space of the eye, the elongate member is configured to maintain a curved configuration that substantially conforms to an anatomical curvature of the posterior chamber and the suprachoroidal space. The invention also provides a deployment tool for inserting the implant described herein into an eye to facilitate conduction of fluid from the posterior chamber of the eye to the suprachoroidal space, and provides a system for facilitating conduction of fluid from the posterior chamber of the eye to the suprachoroidal space.

The invention provides an ophthalmology department minimally invasive drainage implantation device and a delivery system thereof, the ophthalmology department minimally invasive drainage implantation device is a pipe fitting with an inner cavity, the ophthalmology department minimally invasive drainage implantation device is in a two-dimensional wave shape or a three-dimensional spiral shape, and the ophthalmology department minimally invasive drainage implantation device is provided with wave crests and wave troughs; the inner cavity is used for communicating the anterior chamber of the eye with the suprachoroidal space; the external diameter of the minimally invasive drainage implantation device for the ophthalmology department ranges from 0.3 mm to 0.6 mm, and the internal diameter of the minimally invasive drainage implantation device for the ophthalmology department ranges from 0.05 mm to 0.3 mm. The minimally invasive drainage implantation device for the ophthalmology department is prepared from the pipe fitting with the inner cavity, and the loading and implantation requirements can be met; after the drainage tube is released, the drainage tube recovers to be in the preset shape, the drainage effect is achieved, and meanwhile the preset shape of the specific structure can achieve the effects of preventing sliding and enhancing the intraocular fixing effect.

The invention discloses an eye implant which comprises an implant body, the implant body is in a strip shape, the outer contour of the upper surface of the implant body is in a protruding arch shape or a semi-arch shape and used for making contact with a sclera, and the lower surface of the implant body is in a plane shape and used for making contact with a choroid; a longitudinal drainage groove is formed in the upper surface of the implant body in the front-back direction of the implant body. The whole implant body is of a structure that the front end and the rear end are gradually thin and the middle is thick or the rear end is gradually thin and the middle is thick to the front end, the implant body can smoothly enter the suprachoroidal space, an originally narrow gap of the suprachoroidal space is expanded, the outflow amount of aqueous humor from the suprachoroidal space is increased through the longitudinal drainage grooves, the drainage effect is good, blocking is not prone to occurring, and the application range is wide. The effect of reducing the intraocular pressure is achieved. The lower surface of the implant body is planar, so that the attachment area of the implant body and the choroid is larger, the implant body can be stably attached to the choroid, the risk of displacement of the anterior chamber and the choroid is reduced, the implant body is prevented from being exposed to the anterior chamber to touch the cornea, and the risk of loss of corneal endothelial cells is reduced to the maximum extent.

The present invention provides a nanoparticle comprising a scaffold comprising a biodegradable material, an antibody targeting a component of a Bruch's membrane, and an agent for use in a prophylaxis or in a treatment of a pathological change of Bruch's membrane and / or an adjacent tissue, including a retinal pigment epithelium and a choroid of an eye. Additionally, the present invention provides a pharmaceutical composition comprising said nanoparticle and pharmaceutical acceptable excipients for use in a prophylaxis or in a treatment of a pathological change of Bruch's membrane and / or adjacent tissues, including a retinal pigment epithelium and a choroid of an eye. Preferably said agent is an anti-calcifying agent and said pathological change is a calcification of Bruch's membrane and / or the adjacent tissue, including the retinal pigment epithelium and the choroid of the eye.

The utility model discloses a lens for controlling diopter and relieving cervical vertebra strain based on the eye muscle balance theory, the surface of the lens is composed of a far vision area, a middle vision area and a near vision area which are variable in proportion, and a lens base is a prism with a variable base angle. According to the scheme, by means of the well-designed partitioning function and the position angle of the partitioning lens, far, middle and short-distance images can fall on the retina macular fovea center, fatigue, tension and spasm of eye muscles are effectively avoided, eye muscle coordination is improved, excessive adjustment, convergence and excessive sclera pulling through long-time short-distance eye using are avoided, and therefore the effect of improving the eye quality is achieved. The head of a student can be raised to a higher position when the student looks far, the eyeballs are turned upwards and outwards, hurt to the cervical vertebra of the student when the student lowers the head for a long time is further improved, neck soreness and stiffness and tension of muscles of the cervical vertebra and the shoulder are avoided, and the probability of humpback is reduced.

The invention provides an ophthalmology minimally invasive drainage device with an expansion fixing function and a delivery system thereof, the ophthalmology minimally invasive drainage device comprises a drainage main body with a hollow cavity and an expansion fixing device, and the drainage main body comprises a near-end part and a far-end part far away from the near-end part; the expansion fixator is in a two-dimensional plane shape or a three-dimensional shape and is provided with a first end and a second end, the first end is connected with the near end part of the drainage main body, and the second end is connected with the far end part of the drainage main body; the near end part is one end close to the suprachoroidal space and has the length of 0.2-2.5 mm, and the far end part is one end close to the anterior chamber of the eye and has the length of 0.5-3.0 mm. According to the ophthalmology department minimally invasive drainage apparatus with the expansion and fixing functions, the drainage body with the hollow cavity is adopted, and the loading and implanting requirements can be met; after being released, the dilation fixer recovers to a preset shape, so that the dilation fixer can play a role in enhancing the intraocular fixing effect while playing a drainage role, ciliary body dissociation is formed, and then the effects of promoting aqueous humor absorption and inhibiting aqueous humor secretion are achieved.

The invention discloses an idiopathic macular pore patient postoperative retina change clinical observation method, which comprises the following steps: S1, collecting patient data, S2, carrying out an operation, S3, carrying out statistical analysis, S4, comparing data, and S5, concluding, and collecting 32 idiopathic macular pore patients to be included in the group for research. All patients are divided into two groups according to different operation modes, main observation indexes are central retina light sensitivity and peripheral retina light sensitivity, and other observation indexes comprise optimal corrected vision, retina superficial layer blood flow density, retina deep layer blood flow density and macular central depressed choroid thickness. The differences of the observation indexes between the two groups are compared, it is obtained through observation that after the idiopathic macular hole is treated through the vitreous body operation, the retina light sensitivity of the center of the macular part is obviously improved in the early stage of the operation, and improvement of the retina light sensitivity of the center of the macular part is closely related to changes of the retina blood flow density.

The present disclosure provides a device comprising a body, a flexible cannula, and a needle. The cannula is sized and configured to travel between a sclera and a choroid of a patient's eye. The needle is slidably disposed in the cannula and includes a sharp distal tip. The needle translates relative to the cannula between a proximal position and a distal position. The distal tip is positioned inside the cannula when the needle is in the proximal position. The distal tip is positioned outside the cannula when the needle is in the distal position. The needle is resiliently biased to extend along at least one proximal curve through at least one proximal curved needle portion. The needle is resiliently biased to extend along at least one distal curve through at least one distal curved needle portion. The at least one distal curve is different from the at least one proximal curve.

An apparatus for delivering therapeutic agent to an eye comprises a body, a cannula, a hollow needle, and an actuation assembly. The cannula extends distally from the body and is sized and configured to be insertable between a choroid and a sclera of a patient's eye. The actuation assembly is operable to actuate the needle relative to the cannula to thereby drive a distal portion of the needle along an exit axis that is obliquely oriented relative to the longitudinal axis of the cannula. The cannula may be inserted through a sclerotomy incision to position a distal end of the cannula at a posterior region of the eye, between the choroid and sclera. The needle may be advanced through the choroid to deliver the therapeutic agent adjacent to the potential space between the neurosensory retina and the retinal pigment epithelium layer, adjacent to the area of geographic atrophy.

The utility model relates to a pair of glasses capable of shortening an eye axis, which comprises a frame body, and the frame body comprises a front frame for fixing lenses, supports arranged at the left end and the right end of the front frame, and support legs rotationally connected with the supports; when the supporting legs are opened, the supporting seats are attached to the end faces of the adjacent ends of the supporting legs. A groove is formed in the side wall, facing the human eyes, of the front frame, a light guide strip is arranged in the groove, and a light emitting face is arranged on the side wall, facing the human eyes, of the light guide strip. The inner wall of the groove is provided with a channel penetrating to the end face of the support adjacent to the groove. The light guide strip is provided with an extension part extending into the channel; a light-emitting component for emitting light into the extending part is arranged on the supporting leg; when in use, the light with specific wavelength is emitted by the light-emitting component to irradiate human eyes, so that the choroid thickness of eyeballs is increased, the purpose of reducing the eyeball wheelbase can be achieved, the diopter is changed, the effect of reducing the myopia degree is achieved, and the myopia-reducing eyeball is simple in overall structure, small in size and convenient to store and use.

An intraocular implant, kit, and method are disclosed. In one configuration, the implant is a frame that is installable in the suprachoroidal space of the eye and has an arcuate elongated shape that promotes the drainage of aqueous humor through the suprachoroidal space when installed in the suprachoroidal space and is configured to take on an elastically recoverable shape. The frame has a first axial end and a second axial end with respect to the longitudinal axis of the elongated shape, and the arcuate elongated shape defines a channel. The channel has a first axial opening at the first axial end of the frame, a second axial opening at the second axial end of the frame, and a longitudinal opening that extends continuously from the first axial end to the second axial end of the frame.

The present application relates to the field of traditional Chinese medicine, in particular to a kind of traditional Chinese medicine composition for treating central serous chorioretinopathy and application thereof.The present application provides a kind of traditional Chinese medicine composition for treating central serous chorioretinopathy, compared with the prescription of Chunzai Decoction, the traditional Chinese medicine composition of the present application increases the efficacy of promoting blood circulation and removing blood stasis, soothing the liver and relieving depression, clearing the liver and improving eyesight, clearing heat and reducing phlegm on the basis of Chunzai Decoction warming yang, transforming qi, reducing water and removing dampness;Compared with using Chunzai Decoction alone, the curative effect of patients using the traditional Chinese medicine composition is more direct, from 2-3 weeks to 1 week, and the curative effect is accelerated.And the traditional Chinese medicine composition of the present application has been used for about 2 years, 2 / 3 of the 112 patients can see effect in 1 week, and no recurrence is found within 3 months.

The invention discloses an eye movement guiding device for eye muscle exercise and a using method thereof, and relates to the technical field of vision health care instruments, the eye movement guiding device comprises a shell, a multi-dimensional adjusting mechanism and a sighting mark; the multi-dimensional adjusting mechanism is arranged in the shell, the sighting mark is arranged on the multi-dimensional adjusting mechanism, and the multi-dimensional adjusting mechanism drives the sighting mark to move in the shell; wherein the multi-dimensional adjusting mechanism comprises an X-axis track, a Y-axis track and a Z-axis track; the Y-axis track is arranged in the shell; the X-axis track is arranged on the Y-axis track, and the Y-axis track is used for driving the X-axis track to slide; the Z-axis track is arranged on the X-axis track, and the X-axis track is used for driving the Z-axis track to slide; the sighting mark is arranged on the Z-axis track, the Z-axis track is used for driving the sighting mark to slide, the eyeballs can rotate along with the sighting mark, ciliary muscles, six extraocular muscles and a choroidal system are synchronously activated, the extraocular muscles improve coordination and glancing ability in three-dimensional track movement, and plane fixation stiffness of short-distance eye use is broken.

The present invention relates to compounds useful for treating diseases or conditions associated with excessive vascularization of the eye, such as corneal neovascularization, iris neovascularization, ciliary body neovascularization, corneal pannus, choroidal neovascularization, retinal neovascularization, wet age-related macular degeneration, proliferative diabetic retinopathy, retinopathy of prematurity, and ischemic retinopathy.

The invention relates to a saffron crocus eye pad and a method for controlling eye axis growth, and belongs to the technical field of eye care products. The eye patch comprises a patch carrier and a plant extraction gel layer coated on the patch carrier, the plant extract gel layer is composed of mulberry leaf extract, chrysanthemum extract, butterflybush flower extract, amur corktree extract, crocus sativus flower extract, lithospermum extract, madder extract, lycium ruthenicum extract, beet root juice powder, natural borneol, menthol, xanthan gum, purified water and other natural components. The crocus sativus flower extract can enhance the blood flow speed of choroid, thicken the choroid and effectively control the growth of an ocular axis, so that the effect of delaying or improving the development of myopia is achieved. According to the gel layer, a hydrogel structure is formed through xanthan gum, natural borneol and menthol are combined to provide cooling and soothing effects, and the gel layer has good skin affinity and use safety.

An ocular access instrument (20) includes an attachment assembly (32) configured to engage a sclera of an eye, and an actuator assembly (34) configured to bear against the sclera. When the attachment assembly engages the sclera, movement of the actuator assembly inwardly against the eye displaces the choroid from the sclera, thereby creating an enlarged suprachoroidal space. The ocular access instrument may also include a needle guide (40) configured to receive the needle and guide the needle into the enlarged suprachoroidal space.

The invention discloses a pathological myopic lesion classification method, system and device and a medium, belongs to myopic lesion classification in artificial intelligence medicine, and aims to solve the technical problem that choroidal lesion classification accuracy is low due to the fact that diagnosis complexity cannot be captured when multiple pathological myopic lesions exist at the same time are classified in the prior art. The method comprises the following steps: acquiring an OCT sample image and a label, constructing and training a myopic lesion classification model, and performing real-time classification; the myopia lesion classification model comprises a shared encoder, a segmentation decoder and a classification decoder; the shared encoder comprises four residual blocks which are arranged in sequence; the segmentation decoder is a semi-supervised divider; the classification decoder comprises a focus focusing module, a pyramid structure feature fusion module and a classification module which are arranged in sequence. A myopia lesion classification model is creatively constructed, a segmentation decoder can automatically identify a choroid structure in an OCT image, and the blank between a traditional clinical index and a deep learning diagnosis system is effectively filled.

The invention provides an application of a probiotic lactobacillus reuteri Y7 for protecting eyes. The probiotic lactobacillus reuteri Y7 can be used for preventing or treating eye inflammatory response, cell apoptosis and retina injury of mammals caused by blue light exposure; the damage of blue light exposure to the retina is retinal atrophy or retinal thickness thinning caused by blue light, macular choroidal neovascularization and retinal photosensitive function disability; the damage of the blue light exposure to the retina can cause macular lesion, especially late dry macular lesion. Besides human beings, the Chinese medicinal composition also has curative effects on dogs, cats and other mammals.

The invention provides a method for extracting and pulling a crystalline lens, which comprises the following steps of: removing redundant connective tissues around, and making a transverse incision in the equator part of an eyeball; the eyeball at the upper half part is lifted outwards together with the vitreous body, and the connected sclera is cut off; the upper half part of the eyeball is placed on the supporting device, and the eyeball wall is embedded between the sclera fixing inner ring and the sclera fixing outer ring; cutting off the whole cornea; the ciliary body and the choroid are retained; the glue is coated on the round hole of the transfer device; the transfer device is adhered to the ciliary body and the choroid, and iris tissue is cut off; cutting off the sclera fixing inner ring and the sclera fixing outer ring; putting the transfer device and the adhered crystalline lens into a traction device; the traction line penetrates out of the traction cover plate; the traction line is tied to a traction hook at the top end of the traction device, the spiral of the traction device is rotated, the traction line is tensioned upwards, and the crystalline lens is driven to be pulled. The traction device is more uniform in traction, simple in structure, low in manufacturing cost, small in size and more suitable for being built in a laboratory.

The invention relates to the technical field of lighting equipment, in particular to a negative oxygen ion eye-protection lamp capable of inhibiting myopia and relieving asthenopia, which comprises an eye-protection lamp body, a lamp post and a negative oxygen ion generator, the eye-protection lamp body is used for emitting full-spectrum light; the negative oxygen ion generator is installed at the joint of the eye protection lamp body and the lamp pole, and the concentration of negative oxygen ions generated by the negative oxygen ion generator is 5000-5000 / cm < 3 >. When the eye protection lamp is used, the negative oxygen ion generator is arranged at the joint of the eye protection lamp body and the lamp pole, the negative oxygen ion generator can generate negative oxygen ions with the concentration of 5000-50000 / cm < 3 >, more dopamine is secreted by a living body through the negative oxygen ions, the fundus blood flow density and the fundus retina cell activity are improved, the choroid thickness is increased, and therefore the eye protection effect is improved. Therefore, the visual comfort is improved, and the effects of inhibiting myopia and relieving asthenopia are achieved.

The invention discloses a retinal vessel three-dimensional imaging system and method based on an ultra-wide-angle laser fundus camera, and relates to the field of medical imaging devices. The problems that layered imaging cannot be achieved through single-wavelength laser in existing fundus imaging, and the scanning angle of an existing dual-wavelength confocal system is limited are solved. The system comprises a multi-wavelength laser generating unit, a semi-transmitting and semi-reflecting element, a galvanometer unit, a chromatic aberration lens, a sample to be detected, a focusing lens and a detector with a pinhole, laser emitted by the multi-wavelength laser generating unit is reflected by the semi-transparent and semi-reflective element, then sequentially passes through the galvanometer unit and the chromatic aberration lens, is emitted to a to-be-detected sample, sequentially passes through the chromatic aberration lens, the galvanometer unit, the semi-transparent and semi-reflective element and the focusing lens after being reflected by the to-be-detected sample, is received by the detector with a pinhole, and reaches the silicon PM; a multi-wavelength retina confocal image is generated from the signals acquired by the silicon PM. The method is also suitable for the field of full-layer three-dimensional imaging from the retina nerve fiber layer to the choroid.

Disclosed is electrical stimulation apparatus and an associated method for delivering therapy to an eye of a patient is disclosed, the apparatus comprising: an implantable device comprising one or more electrodes for delivering therapeutic electrical stimulation to the eye, the implantable device being configured for implanting in a suprachoroidal space between the sclera and choroid layers of the eye. Also disclosed is electroretinography (ERG) apparatus for monitoring an eye of a patient, the apparatus comprising: an implantable device comprising one or more electrodes for monitoring properties of the eye, the implantable device being configured for implanting in a suprachoroidal space between the sclera and choroid layers of the eye. Also disclosed are implantable devices, apparatuses and methods for the eye.

The present application relates to the field of ophthalmic medical technology, especially to an eyeball cornea treatment system based on near-infrared light recognition, which acquires optical information of eyeball cornea and choroid by collecting near-infrared light signals, and performs digitalization and filtering processing on the original image to output processed image data. Combining edge detection and threshold segmentation, choroid defects or atrophic lesion points are identified, and corneal thickness and curvature are measured to determine the energy intensity, irradiation time, wavelength and focusing position of the excimer light beam. According to the parameters, an excimer light beam with a wavelength of 248 nanometers is emitted to irradiate and treat the lesion area, which improves the positioning accuracy of the lesion while avoiding damage to normal tissue structures, and meets the safety and effectiveness requirements of eye treatment.

The invention provides an experimental animal eyeball extraction mark fixing and choroid paving piece positioning device which comprises an annular adjustable ferrule assembly and a square positioning ferrule assembly, the annular adjustable ferrule assembly and the square positioning ferrule assembly are of detachable structures, and the annular adjustable ferrule assembly is connected to the upper surface of the square positioning ferrule assembly in a clamped mode; the annular adjustable ferrule assembly is an annular main body and comprises an adjustable inner ring, the inner diameter of the adjustable inner ring can be elastically adjusted to adapt to eyeballs of different sizes, the technical field of ophthalmology basic experimental animal research equipment is involved, and the inner diameter of the adjustable inner ring of the annular adjustable ferrule assembly can be elastically adjusted to adapt to experimental rodent eyeballs of different sizes. The eyeball marking and taking-out device has the advantages that small eyeballs of young rats and large eyeballs of adult rats can be tightly attached to each other, accordingly, the stability of the eyeballs in marking and taking-out procedures can be guaranteed, eyeball injuries due to improper matching of the ferrules and the eyeballs can be prevented, the application range of the eyeball marking and taking-out device can be expanded, and the universality and the practicability of the eyeball marking and taking-out device can be improved.

An apparatus and method for aiding in the detection of dementia, concussion, other neurologic conditions, retinal, and optic nerve conditions. The apparatus enables the diffusion coefficient of the tissue to be ascertained and studied by directing the light from a laser or other coherent light source at the patient's retina, optic nerve or choroid and measuring the fluctuations in the intensity of the back-scattered light caused by the movement of light scatterers in the tissue. By comparing the measurements to a normal database, or to the subject's previous measurement, in combination with an eye examination and OCT image / measurement the changes caused by the disease and the effectiveness of therapy can be ascertained. The disclosed apparatus allows the incident and detection optics to be attached to ophthalmic devices typically used in ophthalmologic care. Also, where both the incident laser fiber optic and the detection fiber optic are directly connected to goggles, one or more or all of the above-described mirrors may not be necessary, as both fiber optics are preferably directly directed into the eye.

The utility model relates to an organ model which comprises a model body with an inner cavity, a plurality of red venation bodies and a plurality of purple venation bodies for simulating blood capillaries are arranged in the side wall of the model body, and the red venation bodies and the purple venation bodies are located on the side close to the inner surface of the model body. The red venation body and the purple venation body are arranged on the inner surface of the model body, so that the red venation body and the purple venation body are visible from the inner surface of the model body, a plurality of surface venation bodies for simulating coarse vessels are arranged on the inner surface of the model body, and a transparent adhesive layer for simulating mucous membranes is arranged on the inner surface of the model body. The surface vein body is located between the transparent adhesive layer and the inner surface of the model body. The structure and the color level of the blood vessel on the organ model are more consistent with the reality, so that the evaluation test of the image is more in line with the clinical requirements, the manufacturing is simple, the storage is convenient, the test cost can be reduced, the reutilization can be realized, the resource waste is avoided, and the continuity and the result stability of the evaluation test are good.