The invention discloses a heart-lung-soothing honey-fried pill and a preparation method thereof, the heart-lung-soothing honey-fried pill has two prescriptions of deficiency, excess, cold and heat, and is suitable for excess heat. The heart-lung-soothing honey-fried pill is prepared from the following raw materials: radix bupleuri, astragalus membranaceus, rhizoma atractylodis macrocephalae, dandelion, oriental wormwood, poria cocos in Yunnan, rhizoma alismatis, charred triplet, agastache rugosus, rhizoma cyperi, musk, salviae miltiorrhizae, safflower carthamus, elecampane, pericarpium citri reticulatae, radix rehmanniae, radix rehmanniae preparata, radix polygoni multiflori preparata, ephedra, coptis chinensis, golden cypress, radix ophiopogonis, semen plantaginis, angelica sinensis, leonurus, polygala tenuifolia, liquorice, rhizoma polygonati, ligusticum wallichii and mirabilite. The heart-lung-soothing honey-fried pill provided by the invention has the functions of treating liver, spleen, kidney and intestinal tract, so that endocrine disorder of a human body returns to normal, and the heart-lung-soothing honey-fried pill relieves vasospasm, eliminates vascular stenosis, reduces blood vessel pressure, reduces blood viscosity to achieve heart and lung soothing effect by diffusing the lung, soothing the liver, regulating qi, clearing damp, reducing phlegm, promoting blood circulation to remove blood stasis, clearing away heat and toxic materials, tonifying qi, nourishing blood, moistening and relaxing bowels, nourishing yin and yang of the kidney and eliminating food retention.