Photoluminescent nano particle as well as preparation method and application thereof

A technology of fluorescent nanoparticles and particles, which is applied in the field of fluorescent nanoparticles based on rare earth complex fluorescent dyes and its preparation, can solve the problems of fluorescence quenching, large particle size, strong scattering signal, etc., and achieve large Stocks shift and excellent luminescence performance , the effect of high luminous brightness
CN102134253AInactive Publication Date: 2011-07-27PEKING UNIV
4 Cites 18 Cited by

Patent Information

Authority / Receiving Office
CN Β· China
Patent Type
Applications(China)
Current Assignee / Owner
PEKING UNIV
Publication Date
2011-07-27
Estimated Expiration
Not applicable Β· inactive patent

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The invention discloses a photoluminescent nano particle as well as a preparation method and an application thereof. The photoluminescent nano particle is composed of a carboxyl-containing copolymer matrix material and a rare earth fluorescent dye dispersed in the matrix material. The preparation method of the fluorescent nano particle comprises the following steps: dissolving the rare earth compound fluorescent dye and the copolymer in an organic solvent which is capable of being miscible with water; and adding the solution in water, so that the fluorescent nano particle is formed by utilizing a coprecipitation-self assembly process. The fluorescent nano particle has the advantages of excellent long wave excitation luminescence property and good stability, and has a surface carboxyl group for coupling biomolecules. A biological probe based on the fluorescent nano particle has a wide application prospect in the aspects of high-sensitivity fluorescent immunoassay, biological imaging and the like.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The present invention relates to a class of photoinduced nanoparticles and a class of rare earth complex fluorescent dyes that can be used to prepare such nanoparticles and their preparation methods and applications, especially a class of fluorescent nanoparticles based on rare earth complex fluorescent dyes and their preparation Methods and applications. Background technique

[0002] Fluorescent probes of rare earth complexes have important applications in the fields of biological imaging, DNA detection, and immunoassay. Its main advantage is that rare earth complexes have the characteristics of longer luminescence lifetime, larger Stokes shift, and sharp line emission peaks. These characteristics make it possible to effectively filter background signal interference through time-resolved technology in biochemical analysis, achieve high-sensitivity detection, and avoid the biosafety problems caused by traditional radiolabeling methods.

[0003] Since...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More