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812results about How to "Protection stability" patented technology

Preparation and application of exosome secreted by human derived blood or mesenchymal stem cell

InactiveCN103767985AAvoid blocking, not easily absorbed by cellsProtection stabilityCosmetic preparationsSenses disorderStem cell cultureSomatic cell
The invention discloses preparation and application of exosome secreted by human derived blood or mesenchymal stem cell. The preparation process of exosome comprises: extracting mesenchymal stem cells from health-human body blood or a stem cell culture supernatant, performing in-vitro culture and amplification, and utilizing means such as low-temperature separation, purification and the like to prepare high-purity high-bioactivity exosome. The blood or mesenchymal stem cell secreted exosome is added into medicines, health-care products and cosmetics according to ratios for developing of products with bioactivity, is capable of effectively regulating and controlling body cell signal transduction, activating cell regeneration, enhancing health cell proliferation and differentiation capacity, further regulating physiologic restoration or removing damaged, pathologic and aged cells of a body, fundamentally changing body physiologic functions, and helping to generate anti-tumor treatment effect by adjusting cellular immunity. The blood or mesenchymal stem cell secreted exosome is applicable to fields of medical science, health care and beauty treatment, and has wide application prospect.
Owner:珠海霍普金斯医药研究院股份有限公司

Floating breakwater doubling as wave power generation device

The invention relates to the technical field of breakwater engineering and wave power generation, in particular to a floating breakwater generation device arranged in open sea. The floating breakwater generation device comprises floating members, air turbine generator sets, air chambers, airflow passages, mooring systems and signal transmission devices, and is characterized in that the floating members are respectively connected with concrete anchor blocks at the sea bottom through anchor chains; a plurality of wave dissipating perforations penetrating through a floating body are formed in the head-sea face of each floating member; the air turbine generator sets are respectively arranged in the airflow passages; the floating bodies are driven by waves to vertically move, so that water in the air chambers vibrates and air in the air chambers is pushed to move, and the air turbine generator sets are further driven to generate electricity. The floating breakwater generation device disclosed by the invention has the characteristics of being stable in structure, low in erection cost, high in generation conversion efficiency, convenient to maintain, and the like, and can be applied to sea areas with deep water, high waves and complex terrain; while wave impacts are weakened and a steady water area environment is provided for surrounding water areas, the waves can be converted into electric energy, and the electric power supply problem of harbor district or island residents is effectively solved.
Owner:CHANGSHA UNIVERSITY OF SCIENCE AND TECHNOLOGY

Drug-loading nano-micelles, and preparation method and application thereof

The invention relates to drug-loading nano-micelles, and a preparation method and an application thereof. According to the to drug-loading nano-micelles, a polyethylene glycol derivative-polylysine-polyleucine amphiphilic triblock copolymer is adopted as a carrier, and self-assembly is carried out in a water solution, such that nano-micelles with a three-layer structure transferring gene and medicine are formed. With the hydrophobic effect between polyleucine, the copolymer forms a core of the micelles in water, such that a hydrophobic medicine docetaxel is entrapped. With polylysine, the nano-micelles are positively charged, such that negatively charged anti-apoptotic protein small interfering RNA can be bonded. Polyethylene glycol is used for protecting the stability of the nano-micelles loading the medicines and gene, and a cycle time of the nano-micelles in vivo is prolonged. The nano-micelles are used for loading both an anti-apoptotic protein small interfering RNA gene medicine and a docetaxel medicine, such that the gene treatment medicine and the chemotherapeutic medicine cooperates in treating cancer, and a synergetic effect of the two medicines can be developed. Therefore, a direction is provided for better treatment of breast cancer.
Owner:SHENZHEN INST OF ADVANCED TECH CHINESE ACAD OF SCI

Broadband terahertz linear polarization wave asymmetric transmission device based on metamaterial

The invention discloses a broadband terahertz linear polarization wave asymmetric transmission device based on a metamaterial, and belongs to the field of transmission control devices of electromagnetic waves. The device comprises several basic units which are periodically arranged on an xy plane in the same direction, wherein each basic unit comprises five layers of structures which are arrangedsequentially, namely the dielectric layer 1, the metal layer 2, the dielectric layer 3, the metal layer 4 and the dielectric layer 5 from top to bottom in sequence, and the thickness of the dielectriclayer 3 is generally far larger than the that of the dielectric layer 1 and the dielectric layer 5; the metal layer 2 and the metal layer 4 are metal graphs which are constituted at the two sides ofthe dielectric layer 3 through technologies like photoetching or electron beam lithography; the graph constituted by the metal layer 4 is obtained by rotating the graph of the metal layer 2 by 90 degrees along the axis or through mirror symmetry. Dielectric film at the upper layer and the lower layer can be used for protecting the metal layers against abrasion and the stability of the device. Thebroadband terahertz linear polarization wave asymmetric transmission device is simple in structure and easy to prepare; one-way transmission of broadband terahertz linear polarization conversion is effectively achieved, and the device has an important significance in developing terahertz functional devices.
Owner:BEIJING UNIV OF POSTS & TELECOMM

Detection kit for ischemia modified albumin

The invention relates to the technical field of detection of ischemia modified albumin content, and in particular to a detection kit for ischemia modified albumin. The kit includes a reagent 1 and a reagent 2. The reagent 1 contains a buffer, cobalt chloride, a stabilizer and a preservative; and the reagent 2 contains a buffer, dithiothreitol, a stabilizer, a reducing protective agent and a preservative. The kit can accelerate the binding efficiency of cobalt ions with normal albumin, and the cobalt ions fully integrate with normal albumin in a certain period of time, so as to ensure the accuracy of the detection result on a sample by the reagent; the kit protects the stability of dithiothreitol in the solution, and does not affect the binding of dithiothreitol with cobalt ions, so as to ensure that an open reagent bottle can be stably kept in a dark place for 30 days at room temperature and a closed reagent bottle can be stably kept at 2-8 DEG C for 12 months, and fully meet the needs of clinical laboratory; and the kit accelerates the combination of dithiothreitol with cobalt ions, so that the reagents reach reaction endpoints as soon as possible, thereby ensuring the efficient detection effect of reagents and significantly improving the accuracy of reagent detection.
Owner:BIOBASE BIODUSTRY (SHANDONG) CO LTD

Method for roadway driving along goaf under original roadway top plate of fully mechanized top coal caving goaf

The invention discloses a method for roadway driving along a goaf under an original roadway top plate of a fully mechanized top coal caving goaf. An air return roadway of a lower section and a conveying roadway of an upper section are arranged on an identical position, when a first mining face is stoped, the top plate of the roadway and the coal wall of one side of entity coal are maintained through coal filling sacks to be free from the damage of movement of overlying rock, and maintain the relative integrity. Top coal on an end socket support on one side of the roadway goaf is lowered down, and serves as a coal edge of one side of the roadway goaf after grouting reinforcement. After the first mining face is excavated, the overlying rock is stable in movement, and the pressure of the surrounding rock of the roadway is released completely, tunneling is then carried out on the coal filling sacks and the plumped bottom plate of the roadway, and the fact that tunneling work is carried out in a pressure relieved area is guaranteed. Compared with the prior art, the method has the advantages of being safe, efficient, small in coal loss, low in cost and high in quality of roadway projects. The method for the roadway driving along the goaf under the original roadway top plate of the fully mechanized top coal caving goaf is researched and finished through a project with the number of 51374137 of the Natural Science Foundation of China.
Owner:SHANDONG UNIV OF SCI & TECH

Three-dimensional mobile platform and ICP torch tube positioning device applied therewith

The invention provides a three-dimensional mobile platform which is composed of an X-direction mobile station, a Y-direction mobile station and a Z-direction mobile station which are mutually independent and are correspondingly in X direction, Y direction and Z direction respectively, wherein the X-direction mobile station and the Y-direction mobile station are same in structure and form a cross-shaped structure together; and the X-direction mobile station is arranged on the bottom, the Y-direction mobile station is arranged on the X-direction mobile station and the Z-direction mobile station is arranged on the top. The invention also provides an ICP torch tube positioning device which comprises the three-dimensional mobile platform and an ICP light source generation apparatus, wherein the ICP light source generation apparatus is arranged on a bearing platform of the Z-direction mobile station of the three-dimensional mobile platform. The ICP light source generation apparatus comprises a torch tube, a torch tube clamp seat, an RF coil and a high frequency generator, wherein the torch tube clamp seat is fixedly arranged on the bearing platform; the torch tube is arranged inside the RF coil; and the two ends of the RF coil are in threaded connection with the copper joints of the high frequency generator respectively. The beneficial effects are that: the three-dimensional mobile platform is stable in operation and precise in positioning; the three-dimensional mobile platform is applied to the ICP torch tube positioning device, so that repeated accurate positioning of the torch tube is realized, three-dimensional mobile platform and the ICP torch tube positioning device are structured compactly and highly-reliable.
Owner:CHINA UNIV OF GEOSCIENCES (WUHAN)

Micrometer/nanometer fiber composite filtering material and preparation method thereof

The invention discloses a micrometer/nanometer fiber composite filtering material and a preparation method thereof. The material comprises nanometer fiber and a single-layer micrometer fiber net; andthe structure is as follows: single or bunchy nanometer fiber is distributed on the surface of the single-layer micrometer fiber net uniformly or is embedded in a fiber assembly gap of the single-layer micrometer fiber net uniformly. The method comprises the following steps: preparing electrostatic spinning liquid; preparing the single-layer micrometer fiber net from micron-sized fiber and conveying the single-layer micrometer fiber net to a net conveying curtain with meshes; starting to perform electrostatic spinning by using the electrostatic spinning liquid, jetting single or bunchy nanometer fiber on the single-layer micrometer fiber net uniformly from an electrostatic spinning nozzle to form a single-layer micrometer/nanometer fiber composite net; and forming a continuous multi-layerstructure composite fiber net by using the single-layer micrometer/nanometer fiber composite net by a cross lapping mode, and performing mechanical consolidation to obtain the micrometer/nanometer fiber composite filtering material. The method is simple in production process, high in controllability and easy in industrialization.
Owner:TIANJIN POLYTECHNIC UNIV

Preparation method of mulberry fruit wine

The invention relates to a preparation method of a mulberry fruit wine. The preparation method comprises the following steps of (1) preparing a mulberry pulp solution; (2) heating the mulberry pulp solution, then, mixing the mulberry pulp solution with water, and regulating sugar content to prepare a mixed juice; (3) inoculating a yeast into the juice, and fermenting to prepare a fermentation solution; (4) adding pectinase into the fermentation solution, adding egg white powder, and filtering to prepare a raw wine solution; (5) regulating the alcoholic strength of the raw wine solution, putting the raw wine solution into canful storage in a dark place, and degerming to obtain the mulberry fruit wine. Raw mulberry juice is treated in ways of heating and passivating the activity of polyphenol oxidase, so that the stabilities of nutrient substances in mulberries and color agents in a brewing process are protected. In addition, the polyphenol substance loss caused by polyphenol oxidase is reduced through heating and passivating the activity of polyphenol oxidase and cutting off a brown stain path; due to the combination of clarification treatment, the problem of easily-caused melanin sedimentation of the mulberry fruit wine is solved, and the mulberry fruit wine with stable quality is obtained.
Owner:青岛紫斐农业科技发展有限公司

Lithium phosphate coated lithium iron phosphate electrode and preparation method thereof

The invention relates to a lithium phosphate coated lithium iron phosphate electrode and a preparation method thereof, belonging to the technical field of electrode materials for lithium secondary batteries. The surface of the lithium iron phosphate electrode is coated with nanoscale glassy state lithium phosphate. The electrode preparation method comprises the following steps of: mixing lithium phosphate powder and an organic solvent, carrying out ball-milling on the mixture to form pulp, drying the pulp to obtain powder, compacting the powder into a lithium phosphate target precursor, and then calcining to obtain a lithium phosphate target; carrying out magnetron sputtering on lithium iron phosphate electrode (serving as substrate) and the lithium phosphate target to obtain the lithium phosphate coated lithium iron phosphate electrode, wherein the distance between the target and the substrate is 4-8cm, and the background intensity of pressure is less than or equal to 10*10<-5>Pa. The electrode has high lithium-ion conductivity, and also the capacity of the electrode is improved; the coated lithium phosphate has good chemistry and electrochemical stability and can be used for protecting the stability of the electrode structure; the preparation method is simple and low in cost; and the large-scale production is easy to realize.
Owner:BEIJING INSTITUTE OF TECHNOLOGYGY

Preparation method of graphite carbon coated iron-nitrogen-carbon solid-phase Fenton catalyst and its application

The invention relates to the technical field of preparing solid-phase Fenton catalyst, in particular to a preparation method of graphite carbon coated iron-nitrogen-carbon solid fenton catalyst and its application in organic wastewater treatment. The preparation method of the catalyst comprises the following steps: after mixing and melting the carbon source and the nitrogen source in a certain proportion, adding a certain proportion of iron source, fully stirring and dissolving the mixture, transferring the mixture to an oven at 150-180 DEG C for drying for 12-24 hours, and calcining under theprotection of nitrogen atmosphere to obtain the catalyst. The catalyst prepared by the invention is a graphite carbon coated FeN and Fe3C coexisting iron-nitrogen-carbon catalyst, the size of the nanoparticles is 5-30nm, the specific surface area of the catalyst is 80-300m2/g, and the FeN is the main active site for decomposing hydrogen peroxide. The catalyst of the present invention can be applied to electric-Fenton and Fenton systems and an organic wastewater with pH range of 3-9 is treated. The preparation method of the invention has the advantages of simple steps, easy availability of rawmaterials, excellent performance, high stability and recyclability.
Owner:SOUTH CENTRAL UNIVERSITY FOR NATIONALITIES

Anti-dropping and shock-proof transformer oil tank

The invention discloses an anti-dropping and shock-proof transformer oil tank. The oil tank comprises a shock-absorption spring, a groove and a threaded hole, wherein during use, two pull rods are pulled to squeeze springs in clamping grooves, rotary rods are rotated, so that first door plates are glided, and an opening of a tank body is opened; an oil tank is put on the upper surface of a shock-absorption frame, each nut and the corresponding gliding rod are in threaded tightening, the rotary rods are rotated, each rotary rod between the corresponding pull rod and the tank body is removed, the whole oil tank is fixed through baffles, in the oil tank collision process, the shock-absorption frame is squeezed under the collision force and moves downwards to squeeze the internal shock-absorption springs, the collision force is buffered, and the situation that the shock-absorption springs are out of elasticity due to long-term squeeze can be prevented under the action of rubber pads. A transformer box is convenient to mount, the oil tank is convenient to mount and dismount, anti-dropping and shock-proof, the situation that the oil tank is damaged due to the fact that a transport worker collides the oil tank carelessly in the carrying process can be prevented, the stability and the safety of the oil tank are further protected, and noise produced in the running process of a transformer can be reduced with the adoption of the double-layer tank body.
Owner:洛阳市星合特种变压器有限公司

Electrostatic protection structure and electrostatic protection circuit

ActiveCN104078459AImprove controlIncrease the path of electrostatic dischargeSolid-state devicesSemiconductor devicesElectrostatic dischargeTransistor
The invention provides an electrostatic protection structure and an electrostatic protection circuit. The electrostatic protection structure comprises a PMOS transistor located in a first region of a first N-type trap, a first base doping region located in a second region of the first N-type trap, an NMOS transistor located in a third region of a first P-type trap and a second base doping region located in a fourth region of the first P-type trap. The source region and grid electrode of the PMOS transistor are connected with a power supply end. The drain region of the PMOS transistor is connected with an input / output interface end. The first base doping region is connected with an external trigger voltage regulator circuit. The drain region of the NMOS transistor is connected with the input / output interface end. The grid electrode and source region of the NMOS transistor are connected with a grounding end. The second base doping region is connected with the external trigger voltage regulator circuit. According to the electrostatic protection structure and the electrostatic protection circuit, paths of electrostatic discharge of the electrostatic protection structure are increased, and electrostatic discharge efficiency is improved.
Owner:SEMICON MFG INT (SHANGHAI) CORP

Medicinal composition for improving reproductive capability and preparation method and application thereof

The invention relates to the field of medicaments, and provides a medicinal composition for improving reproductive capability and a preparation method and application thereof. The medicinal composition comprises vitamin E, coenzyme Q10 and/or selenium, and can be used for preparing a medicament and a health product for preventing and treating dysgenesis caused by oxidative stress, endocrine disorder or environmental factor induction when serving as a novel high-efficiency antioxidant. The medicinal composition has the advantages of improving the movement and vitality of sperms, increasing the secretion of sex hormones, protecting the functions of ovaries, improving immunity, improving conception rate, ensuring the nutrition of fetuses, and more effectively treating infertility by combining the conventional medicament vitamin E for treating the infertility and a novel therapeutic medicament coenzyme Q10 and/or selenium and applying different mechanisms for treating the infertility. Compared with any one component in the medicinal composition, the medicinal composition can not only effectively improve curative effect, but also overcome the defects when the components are singly used.
Owner:ZHEJIANG MEDICINE CO LTD XINCHANG PHAMACEUTICAL FACTORY

Preparation process of standard coprophilous fungi freeze-dried powder in transplantation therapy of coprophilous fungi

The invention discloses a preparation process of standard coprophilous fungi freeze-dried powder in transplantation therapy of coprophilous fungi. The preparation process comprises the following steps: (1) preparing standard coprophilous fungi liquid; (2) preparing a freeze-dried protecting agent; and (3) carrying out three-step-method freezing and vacuum drying, wherein the freeze-dried protecting agent is prepared by the steps of respectively adding 10%-20% of mycose, 5%-10% of glycerin and 0.02%-0.05% of vitamin C into sterile normal saline, uniformly mixing, filtering, and removing bacteria. According to the special freeze-dried protecting agent, the activity loss of the coprophilous fungi can be prevented, and the survival rate of the coprophilous fungi is increased; and by virtue ofa special freeze-drying procedure, the coprophilous fungi can rapidly enters a dormant state, so that the activity loss is avoided, and the stability of effective components is effectively protected.Experiments show that by utilizing the freeze-dried powder prepared by virtue of the preparation process, the activity of the coprophilous fungi in excrements is effectively maintained, and the survival rate of the coprophilous fungi is greatly increased.
Owner:南京益恒寿生命科技有限公司
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