The invention discloses a sample preprocessing device provided with an ion chromatograph and used for detecting anions and a use method. The device comprises a sample liquid suck-in pipe, an absorption liquid storage bottle, a flushing liquid storage bottle, a sample liquid peristaltic pump, an absorption liquid peristaltic pump, a flushing liquid injection pump, a dialysis pool, an anion exchanger, a six-way valve, an absorption liquid storage ring and the ion chromatograph. The sample liquid peristaltic pump, the absorption liquid peristaltic pump, the ion chromatograph and the flushing liquid injection pump are all connected with a computer terminal. During dialysis, sample liquid flows, and absorption liquid stops flowing; when absorption liquid is transferred to the absorption liquid storage ring, sample liquid stops flowing, and absorption liquid flows; when the six-way valve is switched, the flushing liquid injection pump flushes absorption liquid in the storage ring to an anion enrichment column in the ion chromatograph. The device has the advantages of online removing heavy metal ions, being low in measurement limit, high in sample adaptability, mild in condition and free of toxic reagents, being matched with the ion chromatograph, and being capable of measuring various anions in sewage or acrylic fiber solvent within 20 min.