66 results about "Mass spectrometry detector" patented technology

The invention discloses a gas component detection method and device based on circulation analysis, and relates to the related field of gas detection.The method comprises the steps that sampling is conducted when dynamically monitored real-time environment conditions meet set environment constraints; activating a chromatographic detector to perform chromatographic separation treatment on a target sample obtained by pretreating the gas sample; activating a mass spectrum detector to perform mass spectrum analysis on a first component in the multiple components to obtain a first mass spectrum; calling a mass spectrum identification plan to analyze the first mass spectrum to obtain a first detection result, and forming a target detection result; performing multi-dimensional property collection on the target sample based on a predetermined sample property to obtain a target property parameter; and correcting the target detection result by taking the combined detection fitness obtained by analyzing the target property parameters as a weight coefficient. The technical problem that existing gas component detection is insufficient in accuracy, comprehensiveness and reliability is solved, and the technical effect of improving the detection accuracy, comprehensiveness and reliability is achieved.

The invention discloses a method and system for measuring and calculating volatile organic compounds in exhaust gas discharged by a stationary pollution source, and the method comprises the steps: determining a sampling position and a sampling point of the exhaust gas discharged by the stationary pollution source, collecting the main product yield, main raw material or fuel consumption of a preset enterprise, and building a database; the method comprises the following steps: collecting waste gas through a waste gas sampling device, acquiring a waste gas chromatogram by adopting a mass spectrum detector, acquiring low-molecular-weight components by adopting a flame ionization detector FID, and acquiring volatile organic components; dividing the molecular weight low components into different concentration series, performing gas chromatographic analysis, drawing a working curve, and calculating correlation coefficients of the molecular weight low components of different concentration series and response areas; analyzing other compounds by adopting a mass spectrometric detector, calculating correlation coefficients of other compounds and response areas, calculating the concentration of the volatile organic compounds, and establishing pollution source data according to the database; and carrying out regression analysis by utilizing the database and the volatile organic compound concentration, and outputting a result.

A 3,5,5-trimethylhexanoic acid composition containing 3,5,5-trimethylhexanoic acid and t-butyl alcohol in which the t-butyl alcohol concentration in terms of toluene-d8 measured by gas chromatography-olfactometry / mass spectrometry under the conditions below exceeds 0 ppb by volume and is 200 ppb by volume or less is provided. The composition is excellent in sulfuric acid coloring evaluation,(Measurement Conditions)The 3,5,5-trimethylhexanoic acid composition is concentrated, andThe concentrated sample is measured by gas chromatography-olfactometry using a column using dimethylpolysiloxane as a stationary phase, and the structure of a measured component is analyzed with a mass spectrometry detector.

The invention relates to the field of medicine detection, and particularly provides a method for detecting the residual content of triethanolamine by ion exchange-high performance liquid chromatography, and the chromatographic conditions in the method are as follows: a chromatographic column adopts a bonded cation exchange medium sulfonic group or carboxyl as a filler; a mobile phase is a phosphate buffer solution, and isocratic elution is carried out. According to the method disclosed by the invention, the triethanolamine does not need to be subjected to pre-column derivatization, and macromolecular protein and triethanolamine separation development (direct flow-through of macromolecular protein) is also not needed, so that the problem that the macromolecular protein is precipitated and removed to detect the triethanolamine when the gas chromatography is used is solved; and the problem that other detector modules such as a mass spectrum detector, an evaporative light detector and an electric conductivity detector need to be equipped and maintained is also solved. The method has the advantages of simple operation, accurate result, small interference and high sensitivity.

The invention relates to the technical field of mass spectrometers, in particular to an intelligent function optimization method for an inductively coupled plasma mass spectrometer, which comprises the following steps: S1, multi-parameter real-time monitoring: acquiring plasma torch temperature, ion lens voltage and mass spectrum detector noise parameters in real time through an embedded sensor array; s2, intelligent control adjustment: dynamically adjusting the power of a radio frequency generator and the carrier gas flow by adopting a self-adaptive fuzzy PID controller; s3, stability prediction modeling: establishing a plasma stability prediction model based on a deep belief network DBN, and outputting optimization parameters according to real-time acquired data; s4, virtual verification optimization: simulating the influence of parameter adjustment on mass spectrum resolution through a digital twin system; through multi-sensor monitoring, self-adaptive control and digital twinborn verification, the analysis precision and stability are remarkably improved, the matrix interference problem is effectively solved through the intelligent pretreatment technology, reliable operation of equipment is guaranteed through a three-level emergency mechanism, and manual intervention and maintenance cost are greatly reduced.

The invention discloses a detection method and a detection system for the cracking gas concentration of a transformer insulating material. The detection method comprises the following steps: performing headspace treatment on to-be-detected insulating oil to realize oil-gas separation in a sample; then the mixed gas is separated through a chromatographic column, the concentration of the dissolved gas is detected and analyzed through a mass spectrometry detector, and the cracking gas comprises at least one of methane, ethane, ethylene, acetylene, hydrogen, carbon monoxide or carbon dioxide. The method specifically comprises the following steps: preparing a to-be-detected insulating oil sample, and treating the to-be-detected insulating oil sample by adopting headspace to realize oil-gas separation in the sample; separating the mixed gas by adopting a chromatographic column, and then detecting and analyzing the dissolved gas by adopting a mass spectrometry detector; preparing a standard gas for dissolving the gas, establishing a calibration curve, and quantitatively calculating the concentration of the cracking gas through the calibration curve. The method can accurately detect methane, ethane, ethylene, acetylene, hydrogen, carbon monoxide and carbon dioxide gases, and has the characteristics of high detection sensitivity, good repeatability, simplicity and convenience and the like.

The present application is applicable to the field of medical devices, and discloses a liquid chromatography-mass spectrometry apparatus and a control method for the liquid chromatography-mass spectrometry apparatus. The liquid chromatography-mass spectrometry apparatus comprises a sample storage device, a pretreatment device, a chromatography device, a mass spectrometry detection device, and a controller. The chromatography device comprises a test solution preparation channel, a test solution transfer assembly, a liquid phase fluid delivery assembly, and a chromatography column. An operating pressure outputted by the liquid phase fluid delivery assembly is less than or equal to 20 MPa. The length of the chromatography column is greater than or equal to 3 mm and less than or equal to 35 mm. A sample comprises a target substance to be measured, and the target substance to be measured comprises at least one of vitamin D, a steroid hormone, and a catecholamine. The present application reduces costs of the liquid chromatography-mass spectrometry apparatus.

This invention relates to the field of medical devices and discloses a liquid chromatography-mass spectrometry (LC-MS) device and a control method for the LC-MS device. The LC-MS device includes a sample storage device, a pretreatment device, a chromatographic element, a mass spectrometry detection device, and a controller. The chromatographic element includes a reagent preparation channel, a reagent transfer assembly, a liquid flow delivery assembly, and a chromatographic column. The liquid flow delivery assembly is used to drive the reagent in the reagent preparation channel through the chromatographic column to adsorb the reagent onto the column, and to drive the liquid flow through the chromatographic column to elute the adsorbed reagent to form the analyte. The pretreatment device uses magnetic separation to pretreatment the sample. The operating pressure of the liquid flow delivery assembly is less than or equal to 20 MPa. This invention reduces the cost of LC-MS devices.

1. Name of the product in this design: Mass Spectrometry Detector (Doping Detector). 2. Purpose of this design: For doping detection. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: 3D view 1.

The application discloses a single-cell online prolonging lysis mass spectrometry flow analysis method. A cell suspension sample is injected into a separation capillary, a front section of the capillary is spirally wound to realize single dispersion of the cells, and a part of a rear section of the capillary is located in an ultrasonic device to realize online ultrasonic lysis, localized single-cell lysis contents are obtained, the content solution gradually enters a non-contact electrospray needle to realize ionization, and finally enters a mass spectrometry detector for detection. Meanwhile, the analysis coverage of weakly polar compounds can be improved by combining a plasma generation device. The method can realize single-cell analysis with high throughput and high metabolite coverage, and by means of a prolonged single-cell detection window, the collection of metabolite primary mass-to-charge ratio information and the identification of secondary structures under high resolution can be realized, including qualitative and quantitative analysis of positional isomers, so that the method has wide application prospects in the fields of cell identification, cell typing, differential substance research, tumor diagnosis and biomarker mining.

The application discloses a method for widening the injection mass range of a linear ion trap / time-of-flight mass spectrometer, and discloses a linear ion trap / time-of-flight mass spectrometer, which widens the external ion injection mass range of the linear ion trap / time-of-flight mass spectrometer through a segmented multi-stage rod, a bias voltage and a step trapping voltage strategy; when external ions are injected, only ions within a certain mass range can reach a mass spectrometer detector due to the difference in the movement speed of light ions and heavy ions, and the limited mass range seriously limits the analysis performance of the linear ion trap / time-of-flight mass spectrometer; the segmented multi-stage rod, the bias voltage and the step trapping voltage strategy can widen the mass range of the linear ion trap / time-of-flight mass spectrometer to which external ions are injected.

The invention relates to the field of gas analysis and analysis of volatile organic substances, is intended for the generation of ions with soft ionization and can be used as an ion source in gas chromatographs (GC) with a mass spectrometric detector and other analytical instruments. A mass spectrometer with the said ion source and a method of ionization using the mass spectrometer are also described. The technical result consists in simplifying the design, reducing the mass and dimensions of the mass spectrometer and the ion source, ensuring controlled fragmentation of molecules, including eliminating unwanted fragmentation of molecules during the ionization process, increasing the sensitivity of the analysis of molecules with the subsequent possibility of easier decoding of mass spectral information, simplification installation and use of the ion source without changing the design of the mass spectrometer, providing a higher signal-to-noise ratio.

1. The name of this design product: Medical direct ionization mass spectrometer. 2. Purpose of the product of this design: Direct ionization mass spectrometry technology is used to ionize the test substance in the test sample, and the concentration of the substance is quickly tested and analyzed through the mass spectrometry detector to provide supporting data for medical diagnosis. 3. The key point of the design of this product lies in the three-dimensional image. 4. The picture or photo that best illustrates the design points: three-dimensional picture.

The invention discloses a power supply control circuit for a mass spectrum detector, and relates to the field of power supply, and the circuit comprises a power supply control module which is used for immediately outputting an immediate signal to a voltage conversion auxiliary module and outputting a delay signal to a voltage conversion module in a delayed manner when the working state of the mass spectrum detector is changed; the voltage conversion module is used for changing the magnitude of the voltage and the magnitude of the current output to the mass spectrum detector after the time delay signal is input, and the beneficial effects are that through the arrangement of the voltage conversion module, when the working state of the mass spectrum detector is changed, the magnitude of the voltage and the magnitude of the current output to the mass spectrum detector are changed, and the power consumption of the mass spectrum detector is matched; the invalid power consumption of the mass spectrum detector is reduced; the voltage conversion auxiliary module is arranged, normal work of the mass spectrum detector in the change process is maintained in the voltage and current change process, and the situation that power supply of the voltage conversion module is insufficient when the mass spectrum detector is converted into a high-power-consumption working state from a low-power-consumption working state is avoided.

The invention discloses a nitrosamine impurity analysis method and application thereof, and belongs to the technical field of pharmaceutical analysis. According to the analysis method for the nitrosamine impurities, an LC-MS / MS method is adopted for analysis, and the chromatographic conditions include that ODS C18 serves as a stationary phase, an acidic aqueous solution serves as a mobile phase A, an organic solvent serves as a mobile phase B, and gradient elution is carried out; the mass spectrum conditions comprise that a triple quadrupole mass spectrum detector is adopted, an electrospray ionization positive ion mode is adopted, and multi-reaction monitoring is carried out; the nitrosamine impurity is prepared from N-nitroso-Vonoprazan (N-nitroso-Vonoprazan). The invention also discloses an application of the analysis method, and the analysis method is used for analyzing impurities in the Vonoprazan fumarate or / and the preparation of the Vonoprazan fumarate. The method is scientific in design and ingenious in conception, and the method for analyzing the nitrosamine impurities in the Vonoprasone fumarate and the preparation Vonoprasone fumarate tablets of the Vonoprasone fumarate is provided for the first time; the analysis method has the advantages of strong specificity, high sensitivity, good accuracy and wide durability.

The application provides a liquid chromatography-mass spectrometry method for detecting phytosterol content in dried blood spots, and belongs to the technical field of detection.The application simplifies a sampling process, uses a disposable blood taking needle and a blood taking card for sampling, replaces traditional serum or plasma samples with obtained dried blood spots, punches a sampling area of the dried blood spot sample through a puncher with a diameter of 3.2 mm, takes three dried blood spot samples, extracts seven kinds of sterol substances contained in the dried blood spot samples through n-hexane, adopts liquid chromatography-mass spectrometry, carries out detection and quantification through chromatographic separation and a mass spectrometry detector, realizes rapid and accurate determination of cholesterols, beta-sitosterols, daidzein, campesterol, dihydrocholesterol, dehydrocholesterol and 7-alkenyl cholestanol, and the method is simple in operation, accurate in quantification, and has a recovery rate of 92.4%-96.7%.

The invention provides a mass spectrometric detection and analysis method for three genotoxic impurities in lamidetan hemisuccinate, which adopts a mass spectrometric detector, selects proper mobile phase, column temperature, flow velocity, chromatographic column and ion pair, performs quantitative analysis on the three impurities in lamidetan hemisuccinate, improves the detection means for quality control of a lamidetan hemisuccinate product, and improves the detection accuracy of the lamidetan hemisuccinate product. The method is convenient and feasible, has high accuracy, can effectively control the quality of lamidetan hemisuccinate, and improves the safety of drugs.

The invention relates to the technical field of drug impurity detection, in particular to a method for detecting the content of dicyandiamide in a lamotrigine key intermediate. Respectively dissolving the test sample and the reference substance in a detection solvent to obtain a test sample solution and a reference substance solution; respectively separating the test solution and the reference solution by adopting a liquid chromatography technology, detecting by adopting a mass spectrometry detector, and calculating the content of dicyandiamide by adopting an external standard method according to a peak area; the liquid chromatography conditions are as follows: a C8 chromatographic column is adopted, and the flow rate is 0.45-0.55 ml / min; the column temperature is 30-40 DEG C; the mobile phase is A: 0.1% formic acid aqueous solution; b: acetonitrile; 8%-12% of A and 92%-88% of B are used for isocratic elution; the mass spectrometry conditions are as follows: in an ESI + positive ion mode, the taper hole voltage is 52V, the parent ion m / z is 85.2, the quantitative ion pair m / z is 85.2 / 68.4, the quantitative ion collision energy is 16V, the qualitative ion pair m / z is 85.2 / 43.5, and the qualitative ion collision energy is 14V. The methodology verifies that the method can be used for quantitatively detecting the content of dicyandiamide in the lamotrigine key intermediate.

This invention relates to the field of medical devices and discloses a liquid chromatography-mass spectrometry (LC-MS) device. The LC-MS device includes a sample storage device, a pretreatment device, a chromatographic element, a mass spectrometry detection device, and a controller. The chromatographic element includes a reagent preparation channel, a reagent transfer assembly, a liquid flow delivery assembly, and a chromatographic column. The reagent transfer assembly is used to transfer at least a portion of the reagent obtained from the pretreatment device to the reagent preparation channel. The liquid flow delivery assembly is used to drive the reagent in the reagent preparation channel through the chromatographic column to adsorb the reagent onto the column, and to drive the liquid flow through the chromatographic column to elute the adsorbed reagent to form the analyte. The length of the chromatographic column is greater than 0 mm and less than 50 mm. This invention reduces the cost of LC-MS devices.

The invention discloses a method for detecting N-nitroso ambroxol in a medicine through LC-MS / MS, and belongs to the technical field of medicine analysis. According to the method for detecting N-nitroso ambroxol in the medicine through LC-MS / MS, the medicine is an ambroxol-containing preparation or ambroxol and a salt bulk drug thereof, and liquid chromatography conditions comprise that octadecylsilane chemically bonded silica is used as a filler, 0.05-0.2% formic acid is used as a mobile phase A, and acetonitrile is used as a mobile phase B for gradient elution; the mass spectrum conditions comprise that a mass spectrum detector and an electrospray positive ion mode are adopted, multi-reaction detection is carried out, and m / z 377.9 to 279.2, m / z 377.9 to 114.3 and m / z 377.9 to 96.3 are selected as detection ion pairs. The method for detecting the ambroxol-containing preparation and the raw materials by adopting LC-MS / MS is high in sensitivity, good in accuracy and suitable for quality control of trace nitrosamine impurities in the preparation and the raw materials.

Provided is a 3, 5, 5-trimethylhexanoic acid composition which contains 3, 5, 5-trimethylhexanoic acid and tertiary butanol, and which has a deuterated toluene-converted concentration of more than 0 to 400 volume ppb (inclusive) as measured by smelling gas chromatography / mass spectrometry after heating in an air atmosphere at 80 DEG C for 4 weeks. The composition has low reproductive toxicity even if stored for a long period of time. (Measurement Condition). The 3, 5, 5-trimethylhexanoic acid composition is concentrated. And measuring the concentrated sample by smelling gas chromatography using a column in which the stationary phase is dimethyl polysiloxane, and analyzing the structure of the measured components by a mass spectrometry detector.

The invention relates to the technical field of drug impurity detection, in particular to a method for detecting the content of cyanamide in a lamotrigine key intermediate. Respectively dissolving the test sample and the reference substance in a detection solvent to obtain a test sample solution and a reference substance solution; respectively separating the test solution and the reference substance solution by adopting a liquid chromatography technology, detecting by adopting a mass spectrometry detector, and calculating the content of hydrazine by adopting an external standard method according to a peak area; the liquid chromatography conditions are as follows: a C18 chromatographic column is adopted, and the flow rate is 0.5-0.7 ml / min; the column temperature is 30-40 DEG C; the mobile phase is A: 0.1% formic acid aqueous solution; b: acetonitrile; 3%-7% of A and 97%-93% of B are used for isocratic elution; the mass spectrometry conditions are as follows: in an ESI-anion mode, the taper hole voltage is 52V, the parent ion m / z is 274.2, the quantitative ion pair m / z is 274.2 / 257.9, the quantitative ion collision energy is 31V, the qualitative ion pair m / z is 274.2 / 194.0, and the qualitative ion collision energy is 39V. The methodology verifies that the method can be used for quantitatively detecting the content of cyanamide in the lamotrigine key intermediate.

The invention relates to the technical field of drug impurity detection, in particular to a method for detecting the content of aminoguanidine in a lamotrigine key intermediate. Respectively dissolving the test sample and the reference substance in a detection solvent to obtain a test sample solution and a reference substance solution; respectively separating the test solution and the reference solution by adopting a liquid chromatography technology, detecting by adopting a mass spectrometry detector, and calculating the content of aminoguanidine by adopting an external standard method according to a peak area; the liquid chromatography conditions are as follows: a C8 chromatographic column is adopted, and the flow rate is 0.95-1.05 ml / min; the column temperature is 30-40 DEG C; the mobile phase is A: 0.1% formic acid aqueous solution; b: acetonitrile; gradient elution is carried out for 0.0 to 0.8 min, and 90 percent of A is obtained; when the time is 0.8-2.0 min, 90%-10% of A is added; in 2.0-4.0 min, 10% of A is taken; the mass spectrometry conditions are as follows: in an ESI + positive ion mode, the taper hole voltage is 38V, the parent ion m / z is 75.2, the quantitative ion pair m / z is 75.2 / 58.4, the quantitative ion collision energy is 11V, the qualitative ion pair m / z is 75.2 / 43.5, and the qualitative ion collision energy is 36V. The methodology verifies that the method can be used for quantitatively detecting the content of aminoguanidine in the lamotrigine key intermediate.

The invention provides a method for detecting six isomers of trinitrotoluene, a separation method in the detection method is a gas chromatographic method, a quantitative detector in the detection method is a mass spectrometric detector, and a qualitative method in the detection method is standard sample verification. A chromatographic column in the gas chromatography is a capillary column; the temperature rise mode of a column oven in the gas chromatography is a programmed temperature rise mode. The rapid detection method for the six isomers of trinitrotoluene has the characteristics of good peak presentation, high resolution, strong repeatability and simple and rapid operation, can realize separation and content determination of the six isomers of trinitrotoluene in one step, saves the test cost, is convenient to popularize and has wide application prospects. And effective guarantee is provided for synthesis process monitoring and product quality control of TNT.

The invention discloses a method for determining the limit I of aristolochic acid in a cough-relieving and phlegm-reducing pill, which comprises the following steps: performing ultrasonic extraction on the cough-relieving and phlegm-reducing pill by using a 70% methanol solution, performing gradient elution by using acetonitrile as a mobile phase A and a 0.1% formic acid solution containing 1mmol / L ammonium acetate as a mobile phase B, and determining the limit I of aristolochic acid in the cough-relieving and phlegm-reducing pill by using a triple quadrupole mass spectrometry detector, the total limit of aristolochic acid I in the cough-relieving and phlegm-reducing pill is measured by multiple reaction monitoring (MRM) ion pairs in an electrospray positive ion (ESI) mode.

The invention relates to the technical field of petrochemical product analysis, in particular to a method for measuring n-alkane content and carbon number distribution of white oil based on gas chromatography-mass spectrometry, which comprises the following steps: carrying out gas chromatography-mass spectrometry detection on a white oil sample to obtain total ion flow and mass spectrometry data; determining retention time and peak area of n-alkanes with different carbon numbers in the total ion chromatogram according to the total ion current and the mass spectrum data; and according to the retention time and the peak area, obtaining the n-alkane content in the white oil sample, the proportion of each carbon number interval and the carbon number distribution. The separation effect is good, the test result is accurate and reliable, the content and carbon number distribution of the n-alkanes in the C12-C34 carbon number interval can be measured, a mass spectrum detector is used, the carbon number distribution interval defining accuracy is improved, a standard sample is not needed for comparison, the detection process is convenient and rapid, and application and popularization are facilitated.

The invention belongs to the technical field of biology, and particularly relates to a marker composition for deletion type alpha thalassemia, a detection reagent and application. The marker composition is a combination of any two polypeptide fragments of P1, P2, P3, P4 and P5; wherein the amino acid sequences of P1-P5 are respectively shown as SEQ ID NO: 1-5 in sequence. The invention also provides a method for separating and determining the peak area ratio of the biomarker composition based on liquid chromatography-tandem mass spectrometry. The method comprises the following steps: 1) separating polypeptide fragments in a blood sample of a patient suffering from deletion type alpha thalassemia by adopting liquid chromatography; and 2) determining by using a mass spectrometry detector, quantifying each peptide fragment by using a peak area integration method, and calculating the peak area ratio of peptide fragment markers. The marker can effectively identify various types of deletion alpha-thalassemia, and rapid screening and preliminary typing of various types of alpha-thalassemia can be realized by calculating the peak area ratio of each peptide fragment marker.

The utility model belongs to the technical field of gas chromatographs, and particularly relates to a gas chromatography-mass spectrometry combined detector which comprises a machine body, a handle is hinged to the outer side of the machine body through a damping shaft, a square plate is connected into the machine body in a sliding mode, and a threaded rod is fixedly connected to the lower end of the square plate. The lower end of the threaded rod is fixedly connected with a base plate, the interior of the machine body is rotationally connected with a limiting block, and the lower end of the limiting block is fixedly connected with a limiting sleeve. Through the arrangement of the threaded rod, the limiting sleeve and other components, the limiting sleeve can be rotated to make threaded movement with the threaded rod, so that the position of the base plate is adjusted, the base plate is matched with the lifting handle to keep the equipment stable, and secondary adjustment is not needed when the equipment is moved on the same plane; the problems that a bottom support of a gas chromatography-mass spectrometry combined detector cannot be adjusted when the gas chromatography-mass spectrometry combined detector is used, and the gas chromatography-mass spectrometry combined detector is not stable when placed are solved.

The invention discloses a method for detecting saponin components in ginseng and a preparation thereof. Relates to the field of medicinal material detection. The method for detecting the saponin components in the ginseng and the ginseng preparation comprises the following steps: S1, taking a ginseng sample or a ginseng-containing preparation, adding an extraction solvent, and extracting to obtain a test solution; s2, the test solution is injected into a liquid chromatograph, a chromatographic column is adopted for gradient elution, and octadecylsilane chemically bonded silica is adopted as a filling agent of the chromatographic column; s3, detecting pseudo-ginsenoside F11, ginsenoside Rf, ginsenoside Rg1, ginsenoside Rb1 and ginsenoside Re by adopting an electrospray ionization source negative ion mode and a multi-reaction monitoring mode of a mass spectrometry detector; a mobile phase used for gradient elution is selected from acetonitrile-water, an acetonitrile-ammonium acetate solution, acetonitrile-ammonium formate, methanol-formic acid or an acetonitrile-tetrahydrofuran-ammonium formate solution. By combining C18 chromatographic column gradient elution with a mass spectrum multi-reaction monitoring (MRM) mode and providing a mobile phase system, the problems of narrow applicability, isomeride interference, strong matrix effect and the like of a method for detecting saponin components of ginseng and preparations thereof in the prior art are effectively solved.

This invention discloses a method and system for measuring volatile organic compounds (VOCs) in exhaust gas from stationary pollution sources. The method includes determining the sampling locations and points for exhaust gas emissions from stationary pollution sources; collecting data on the main product outputs and main raw material or fuel consumption of a pre-defined enterprise and establishing a database; collecting exhaust gas using an exhaust gas sampling device; obtaining exhaust gas chromatography using a mass spectrometer; obtaining low molecular weight components using a flame ionization detector (FID) to obtain VOC components; dividing the low molecular weight components into different concentration series and performing gas chromatography analysis to plot working curves; calculating the correlation coefficients between the low molecular weight components and the response area for different concentration series; analyzing other compounds using a mass spectrometer; calculating the correlation coefficients between other compounds and the response area; calculating the concentration of VOCs; establishing pollution source data based on the database; and performing regression analysis using the database and the VOC concentrations to output the results.