43 results about "Mass spectrometry detector" patented technology

The invention discloses a method and system for measuring and calculating volatile organic compounds in exhaust gas discharged by a stationary pollution source, and the method comprises the steps: determining a sampling position and a sampling point of the exhaust gas discharged by the stationary pollution source, collecting the main product yield, main raw material or fuel consumption of a preset enterprise, and building a database; the method comprises the following steps: collecting waste gas through a waste gas sampling device, acquiring a waste gas chromatogram by adopting a mass spectrum detector, acquiring low-molecular-weight components by adopting a flame ionization detector FID, and acquiring volatile organic components; dividing the molecular weight low components into different concentration series, performing gas chromatographic analysis, drawing a working curve, and calculating correlation coefficients of the molecular weight low components of different concentration series and response areas; analyzing other compounds by adopting a mass spectrometric detector, calculating correlation coefficients of other compounds and response areas, calculating the concentration of the volatile organic compounds, and establishing pollution source data according to the database; and carrying out regression analysis by utilizing the database and the volatile organic compound concentration, and outputting a result.

The invention relates to the technical field of mass spectrometers, in particular to an intelligent function optimization method for an inductively coupled plasma mass spectrometer, which comprises the following steps: S1, multi-parameter real-time monitoring: acquiring plasma torch temperature, ion lens voltage and mass spectrum detector noise parameters in real time through an embedded sensor array; s2, intelligent control adjustment: dynamically adjusting the power of a radio frequency generator and the carrier gas flow by adopting a self-adaptive fuzzy PID controller; s3, stability prediction modeling: establishing a plasma stability prediction model based on a deep belief network DBN, and outputting optimization parameters according to real-time acquired data; s4, virtual verification optimization: simulating the influence of parameter adjustment on mass spectrum resolution through a digital twin system; through multi-sensor monitoring, self-adaptive control and digital twinborn verification, the analysis precision and stability are remarkably improved, the matrix interference problem is effectively solved through the intelligent pretreatment technology, reliable operation of equipment is guaranteed through a three-level emergency mechanism, and manual intervention and maintenance cost are greatly reduced.

The invention discloses a detection method and a detection system for the cracking gas concentration of a transformer insulating material. The detection method comprises the following steps: performing headspace treatment on to-be-detected insulating oil to realize oil-gas separation in a sample; then the mixed gas is separated through a chromatographic column, the concentration of the dissolved gas is detected and analyzed through a mass spectrometry detector, and the cracking gas comprises at least one of methane, ethane, ethylene, acetylene, hydrogen, carbon monoxide or carbon dioxide. The method specifically comprises the following steps: preparing a to-be-detected insulating oil sample, and treating the to-be-detected insulating oil sample by adopting headspace to realize oil-gas separation in the sample; separating the mixed gas by adopting a chromatographic column, and then detecting and analyzing the dissolved gas by adopting a mass spectrometry detector; preparing a standard gas for dissolving the gas, establishing a calibration curve, and quantitatively calculating the concentration of the cracking gas through the calibration curve. The method can accurately detect methane, ethane, ethylene, acetylene, hydrogen, carbon monoxide and carbon dioxide gases, and has the characteristics of high detection sensitivity, good repeatability, simplicity and convenience and the like.

The present application is applicable to the field of medical devices, and discloses a liquid chromatography-mass spectrometry apparatus and a control method for the liquid chromatography-mass spectrometry apparatus. The liquid chromatography-mass spectrometry apparatus comprises a sample storage device, a pretreatment device, a chromatography device, a mass spectrometry detection device, and a controller. The chromatography device comprises a test solution preparation channel, a test solution transfer assembly, a liquid phase fluid delivery assembly, and a chromatography column. An operating pressure outputted by the liquid phase fluid delivery assembly is less than or equal to 20 MPa. The length of the chromatography column is greater than or equal to 3 mm and less than or equal to 35 mm. A sample comprises a target substance to be measured, and the target substance to be measured comprises at least one of vitamin D, a steroid hormone, and a catecholamine. The present application reduces costs of the liquid chromatography-mass spectrometry apparatus.

This invention relates to the field of medical devices and discloses a liquid chromatography-mass spectrometry (LC-MS) device and a control method for the LC-MS device. The LC-MS device includes a sample storage device, a pretreatment device, a chromatographic element, a mass spectrometry detection device, and a controller. The chromatographic element includes a reagent preparation channel, a reagent transfer assembly, a liquid flow delivery assembly, and a chromatographic column. The liquid flow delivery assembly is used to drive the reagent in the reagent preparation channel through the chromatographic column to adsorb the reagent onto the column, and to drive the liquid flow through the chromatographic column to elute the adsorbed reagent to form the analyte. The pretreatment device uses magnetic separation to pretreatment the sample. The operating pressure of the liquid flow delivery assembly is less than or equal to 20 MPa. This invention reduces the cost of LC-MS devices.

1. Name of the product in this design: Mass Spectrometry Detector (Doping Detector). 2. Purpose of this design: For doping detection. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: 3D view 1.

The application discloses a single-cell online prolonging lysis mass spectrometry flow analysis method. A cell suspension sample is injected into a separation capillary, a front section of the capillary is spirally wound to realize single dispersion of the cells, and a part of a rear section of the capillary is located in an ultrasonic device to realize online ultrasonic lysis, localized single-cell lysis contents are obtained, the content solution gradually enters a non-contact electrospray needle to realize ionization, and finally enters a mass spectrometry detector for detection. Meanwhile, the analysis coverage of weakly polar compounds can be improved by combining a plasma generation device. The method can realize single-cell analysis with high throughput and high metabolite coverage, and by means of a prolonged single-cell detection window, the collection of metabolite primary mass-to-charge ratio information and the identification of secondary structures under high resolution can be realized, including qualitative and quantitative analysis of positional isomers, so that the method has wide application prospects in the fields of cell identification, cell typing, differential substance research, tumor diagnosis and biomarker mining.

The application discloses a method for widening the injection mass range of a linear ion trap / time-of-flight mass spectrometer, and discloses a linear ion trap / time-of-flight mass spectrometer, which widens the external ion injection mass range of the linear ion trap / time-of-flight mass spectrometer through a segmented multi-stage rod, a bias voltage and a step trapping voltage strategy; when external ions are injected, only ions within a certain mass range can reach a mass spectrometer detector due to the difference in the movement speed of light ions and heavy ions, and the limited mass range seriously limits the analysis performance of the linear ion trap / time-of-flight mass spectrometer; the segmented multi-stage rod, the bias voltage and the step trapping voltage strategy can widen the mass range of the linear ion trap / time-of-flight mass spectrometer to which external ions are injected.

1. The name of this design product: Medical direct ionization mass spectrometer. 2. Purpose of the product of this design: Direct ionization mass spectrometry technology is used to ionize the test substance in the test sample, and the concentration of the substance is quickly tested and analyzed through the mass spectrometry detector to provide supporting data for medical diagnosis. 3. The key point of the design of this product lies in the three-dimensional image. 4. The picture or photo that best illustrates the design points: three-dimensional picture.

The application provides a liquid chromatography-mass spectrometry method for detecting phytosterol content in dried blood spots, and belongs to the technical field of detection.The application simplifies a sampling process, uses a disposable blood taking needle and a blood taking card for sampling, replaces traditional serum or plasma samples with obtained dried blood spots, punches a sampling area of the dried blood spot sample through a puncher with a diameter of 3.2 mm, takes three dried blood spot samples, extracts seven kinds of sterol substances contained in the dried blood spot samples through n-hexane, adopts liquid chromatography-mass spectrometry, carries out detection and quantification through chromatographic separation and a mass spectrometry detector, realizes rapid and accurate determination of cholesterols, beta-sitosterols, daidzein, campesterol, dihydrocholesterol, dehydrocholesterol and 7-alkenyl cholestanol, and the method is simple in operation, accurate in quantification, and has a recovery rate of 92.4%-96.7%.

The invention relates to the technical field of drug impurity detection, in particular to a method for detecting the content of dicyandiamide in a lamotrigine key intermediate. Respectively dissolving the test sample and the reference substance in a detection solvent to obtain a test sample solution and a reference substance solution; respectively separating the test solution and the reference solution by adopting a liquid chromatography technology, detecting by adopting a mass spectrometry detector, and calculating the content of dicyandiamide by adopting an external standard method according to a peak area; the liquid chromatography conditions are as follows: a C8 chromatographic column is adopted, and the flow rate is 0.45-0.55 ml / min; the column temperature is 30-40 DEG C; the mobile phase is A: 0.1% formic acid aqueous solution; b: acetonitrile; 8%-12% of A and 92%-88% of B are used for isocratic elution; the mass spectrometry conditions are as follows: in an ESI + positive ion mode, the taper hole voltage is 52V, the parent ion m / z is 85.2, the quantitative ion pair m / z is 85.2 / 68.4, the quantitative ion collision energy is 16V, the qualitative ion pair m / z is 85.2 / 43.5, and the qualitative ion collision energy is 14V. The methodology verifies that the method can be used for quantitatively detecting the content of dicyandiamide in the lamotrigine key intermediate.

This invention relates to the field of medical devices and discloses a liquid chromatography-mass spectrometry (LC-MS) device. The LC-MS device includes a sample storage device, a pretreatment device, a chromatographic element, a mass spectrometry detection device, and a controller. The chromatographic element includes a reagent preparation channel, a reagent transfer assembly, a liquid flow delivery assembly, and a chromatographic column. The reagent transfer assembly is used to transfer at least a portion of the reagent obtained from the pretreatment device to the reagent preparation channel. The liquid flow delivery assembly is used to drive the reagent in the reagent preparation channel through the chromatographic column to adsorb the reagent onto the column, and to drive the liquid flow through the chromatographic column to elute the adsorbed reagent to form the analyte. The length of the chromatographic column is greater than 0 mm and less than 50 mm. This invention reduces the cost of LC-MS devices.

Provided is a 3, 5, 5-trimethylhexanoic acid composition which contains 3, 5, 5-trimethylhexanoic acid and tertiary butanol, and which has a deuterated toluene-converted concentration of more than 0 to 400 volume ppb (inclusive) as measured by smelling gas chromatography / mass spectrometry after heating in an air atmosphere at 80 DEG C for 4 weeks. The composition has low reproductive toxicity even if stored for a long period of time. (Measurement Condition). The 3, 5, 5-trimethylhexanoic acid composition is concentrated. And measuring the concentrated sample by smelling gas chromatography using a column in which the stationary phase is dimethyl polysiloxane, and analyzing the structure of the measured components by a mass spectrometry detector.

The invention relates to the technical field of drug impurity detection, in particular to a method for detecting the content of cyanamide in a lamotrigine key intermediate. Respectively dissolving the test sample and the reference substance in a detection solvent to obtain a test sample solution and a reference substance solution; respectively separating the test solution and the reference substance solution by adopting a liquid chromatography technology, detecting by adopting a mass spectrometry detector, and calculating the content of hydrazine by adopting an external standard method according to a peak area; the liquid chromatography conditions are as follows: a C18 chromatographic column is adopted, and the flow rate is 0.5-0.7 ml / min; the column temperature is 30-40 DEG C; the mobile phase is A: 0.1% formic acid aqueous solution; b: acetonitrile; 3%-7% of A and 97%-93% of B are used for isocratic elution; the mass spectrometry conditions are as follows: in an ESI-anion mode, the taper hole voltage is 52V, the parent ion m / z is 274.2, the quantitative ion pair m / z is 274.2 / 257.9, the quantitative ion collision energy is 31V, the qualitative ion pair m / z is 274.2 / 194.0, and the qualitative ion collision energy is 39V. The methodology verifies that the method can be used for quantitatively detecting the content of cyanamide in the lamotrigine key intermediate.

The invention provides a method for detecting six isomers of trinitrotoluene, a separation method in the detection method is a gas chromatographic method, a quantitative detector in the detection method is a mass spectrometric detector, and a qualitative method in the detection method is standard sample verification. A chromatographic column in the gas chromatography is a capillary column; the temperature rise mode of a column oven in the gas chromatography is a programmed temperature rise mode. The rapid detection method for the six isomers of trinitrotoluene has the characteristics of good peak presentation, high resolution, strong repeatability and simple and rapid operation, can realize separation and content determination of the six isomers of trinitrotoluene in one step, saves the test cost, is convenient to popularize and has wide application prospects. And effective guarantee is provided for synthesis process monitoring and product quality control of TNT.

The invention discloses a method for determining the limit I of aristolochic acid in a cough-relieving and phlegm-reducing pill, which comprises the following steps: performing ultrasonic extraction on the cough-relieving and phlegm-reducing pill by using a 70% methanol solution, performing gradient elution by using acetonitrile as a mobile phase A and a 0.1% formic acid solution containing 1mmol / L ammonium acetate as a mobile phase B, and determining the limit I of aristolochic acid in the cough-relieving and phlegm-reducing pill by using a triple quadrupole mass spectrometry detector, the total limit of aristolochic acid I in the cough-relieving and phlegm-reducing pill is measured by multiple reaction monitoring (MRM) ion pairs in an electrospray positive ion (ESI) mode.

The invention relates to the technical field of petrochemical product analysis, in particular to a method for measuring n-alkane content and carbon number distribution of white oil based on gas chromatography-mass spectrometry, which comprises the following steps: carrying out gas chromatography-mass spectrometry detection on a white oil sample to obtain total ion flow and mass spectrometry data; determining retention time and peak area of n-alkanes with different carbon numbers in the total ion chromatogram according to the total ion current and the mass spectrum data; and according to the retention time and the peak area, obtaining the n-alkane content in the white oil sample, the proportion of each carbon number interval and the carbon number distribution. The separation effect is good, the test result is accurate and reliable, the content and carbon number distribution of the n-alkanes in the C12-C34 carbon number interval can be measured, a mass spectrum detector is used, the carbon number distribution interval defining accuracy is improved, a standard sample is not needed for comparison, the detection process is convenient and rapid, and application and popularization are facilitated.

The invention discloses a method for detecting saponin components in ginseng and a preparation thereof. Relates to the field of medicinal material detection. The method for detecting the saponin components in the ginseng and the ginseng preparation comprises the following steps: S1, taking a ginseng sample or a ginseng-containing preparation, adding an extraction solvent, and extracting to obtain a test solution; s2, the test solution is injected into a liquid chromatograph, a chromatographic column is adopted for gradient elution, and octadecylsilane chemically bonded silica is adopted as a filling agent of the chromatographic column; s3, detecting pseudo-ginsenoside F11, ginsenoside Rf, ginsenoside Rg1, ginsenoside Rb1 and ginsenoside Re by adopting an electrospray ionization source negative ion mode and a multi-reaction monitoring mode of a mass spectrometry detector; a mobile phase used for gradient elution is selected from acetonitrile-water, an acetonitrile-ammonium acetate solution, acetonitrile-ammonium formate, methanol-formic acid or an acetonitrile-tetrahydrofuran-ammonium formate solution. By combining C18 chromatographic column gradient elution with a mass spectrum multi-reaction monitoring (MRM) mode and providing a mobile phase system, the problems of narrow applicability, isomeride interference, strong matrix effect and the like of a method for detecting saponin components of ginseng and preparations thereof in the prior art are effectively solved.

This invention discloses a method and system for measuring volatile organic compounds (VOCs) in exhaust gas from stationary pollution sources. The method includes determining the sampling locations and points for exhaust gas emissions from stationary pollution sources; collecting data on the main product outputs and main raw material or fuel consumption of a pre-defined enterprise and establishing a database; collecting exhaust gas using an exhaust gas sampling device; obtaining exhaust gas chromatography using a mass spectrometer; obtaining low molecular weight components using a flame ionization detector (FID) to obtain VOC components; dividing the low molecular weight components into different concentration series and performing gas chromatography analysis to plot working curves; calculating the correlation coefficients between the low molecular weight components and the response area for different concentration series; analyzing other compounds using a mass spectrometer; calculating the correlation coefficients between other compounds and the response area; calculating the concentration of VOCs; establishing pollution source data based on the database; and performing regression analysis using the database and the VOC concentrations to output the results.

The invention discloses a high-pressure continuous flow fixed bed reactor for evaluating liquid-phase hydroxylamine nitrate and a use method of the high-pressure continuous flow fixed bed reactor. The high-pressure continuous flow fixed bed reactor comprises a feeding pipeline, a 316 stainless steel straight-through type reaction tube and a condensation tube which are communicated in sequence, the feeding pipeline comprises a gas inlet pipeline and a liquid inlet pipeline which are arranged in parallel; the liquid inlet pipeline is provided with a metering pump along the liquid flow direction; the gas inlet pipeline is sequentially provided with a stop valve, a pressure reducing valve and a flowmeter along the gas flow direction; the liquid inlet pipeline and the gas inlet pipeline are converged before entering the 316 stainless steel straight-through type reaction tube, and a first pressure meter is arranged before convergence; the condenser pipe comprises a gas outlet end and a liquid outlet end, the gas outlet end is provided with a mass spectrum detector, and the liquid outlet end is provided with an off-line ion chromatography detector; a second pressure meter and a back pressure valve are arranged between the gas outlet end and the mass spectrum detector; and the high-pressure continuous flow fixed bed reactor is also provided with a temperature control system, a feeding control system and an analysis system.

The invention discloses a method for measuring the concentration of macrolide antibiotics in domestic sewage. The method comprises the following steps: enriching and purifying macrolide compounds in a treated domestic sewage sample through a non-polar divinyl phenyl neutral polymer solid-phase extraction column and a hydrophilic group-containing polystyrene / divinyl benzene copolymer bonded piperazine group solid-phase extraction column which are connected in series, concentrating, and fixing the volume; and separating the target compound by liquid chromatography, and detecting by a triple quadrupole mass spectrometry detector to obtain the concentration of the macrolide antibiotics in the domestic sewage. The method overcomes the defects of traditional detection, reduces the interference of the matrix effect of the water sample on the internal standard, improves the quantitative accuracy, does not involve expensive materials, can obtain reagent consumables in situ, and saves the detection cost.

The application relates to a mass spectrum ionization source based on high-throughput detection of inert protection and a use method, comprising a closed inert gas protection ionization source, the sampling end of the closed inert gas protection ionization source is provided with an ionization source top-end sealing plug-in valve, the closed inert gas protection ionization source is provided with a spatial position adjusting device, so that in a detection state, the detection end of the closed inert gas protection ionization source can be connected with a mass spectrum detector, the bottom of the closed inert gas protection ionization source is connected with an ionization source bottom-end storage sample piece for storing a detected array probe assembly, the closed inert gas protection ionization source has a sealed working state and an opened sample loading state for transferring a sample to be detected, and the closed inert gas protection ionization source is provided with a metal electrode close to the mass spectrum detector end for completing ionization of the sample to be detected.

This invention relates to the field of medical devices and discloses a liquid chromatography-mass spectrometry (LC-MS) coupling device. The device includes a sample storage device, a pretreatment device, a chromatographic element, a mass spectrometry detection device, and a controller. The chromatographic element includes a reagent transfer assembly, at least one first liquid chromatography channel, and at least one second liquid chromatography channel. The first liquid chromatography channel is used to elute a first reagent with a liquid fluid driven by a first operating pressure to form a first analyte. The second liquid chromatography channel is used to elute a second reagent with a liquid fluid driven by a second operating pressure to form a second analyte. The first operating pressure is less than or equal to 20 MPa, and the second operating pressure is greater than 20 MPa. This invention reduces the cost of LC-MS coupling devices.

This application relates to the field of mass spectrometry analysis and detection technology, and in particular to a detection method for enhancing ion recognition, comprising the following steps: Step 1, placing an ultrasonic standing wave device within an ion source, the ultrasonic standing wave device including at least two oppositely arranged acoustic transducer units for emitting sound waves of the same frequency and opposite propagation directions to superimpose and form an ultrasonic standing wave field, and also including a triaxial adjustment mechanism; Step 2, the two acoustic transducer units extending into the ion source cavity and located on both sides of the nozzle, adjusting the position of the acoustic transducer units using the triaxial adjustment mechanism so that the acoustic transducer units are close to the rear of the nozzle, and the center height of the acoustic transducer units is lower than the tip of the nozzle; Step 3, adjusting the spacing between the two acoustic transducer units; Step 4, aligning the standing wave node axially with the entrance of the mass spectrometer detector. This method can enhance the focusing of sample ions, thereby improving the ion recognition effect of the mass spectrometer detector, without changing the internal structure of the ion source.

The present invention relates to a vinyl chloride-based polymer, a resin composition comprising same, and a method for preparing same, wherein the vinyl chloride-based polymer has a degree of polymerization of 2800-5000, and has a peak in at least one of a region having a retention time of 1.5 to 2.5 minutes and a region having a retention time of 4 to 6 minutes in a graph obtained as a result of liquid chromatography / quadrupole mass spectrometry analysis performed under the following conditions.

The invention discloses a liquid chromatography-tandem mass spectrometry detection method for di-tert-butyl dicarbonate residue in a bulk drug. The invention relates to the technical field of pharmaceutical analysis, and discloses a BOC (Boron Oxidized Carboxylic Acid) preparation method which comprises the following steps: reacting BOC anhydride with phenylpropionic acid under the heating condition of alkaline tetrahydrofuran by taking a phenylpropionic acid tetrahydrofuran alkaline solution as a deriving agent. The method provided by the invention can effectively detect the residue of BOC anhydride in the bulk drug, and the limit of quantitation reaches 0.2 [mu] g / mL; compared with a direct sample injection test method, the sensitivity is higher, the sample preparation process is simple, the operation is safe and simple, the treatment is convenient and rapid, and the detection efficiency is improved; equipment is easy to obtain, a measured chromatographic baseline is stable and does not drift, interference of a mass spectrometric detector is small, and precision and accuracy of the method are improved; the method is used for residue determination of BOC anhydride, has good sensitivity, linear relation, precision, accuracy and stability, and has important research value in the aspects of bulk drug quality research, impurity analysis and control research and the like.

The invention relates to a two-dimensional liquid chromatography-mass spectrometry analysis method and system and a storage medium, and the two-dimensional liquid chromatography-mass spectrometry analysis method comprises the following steps: obtaining type information of a sample introduced by a sample injector, and extracting corresponding preset separation time according to the type information; adjusting the communication between the sample injector and the plurality of chromatographic columns through a switching valve, and feeding a plurality of samples into the corresponding chromatographic columns for one-dimensional separation; according to preset separation time, sending the sample subjected to one-dimensional separation into a two-dimensional liquid phase port for two-dimensional separation, and supplementing a next sample to be analyzed into the chromatographic column; and sending the sample subjected to two-dimensional separation into a mass spectrometry detector for detection. According to the two-dimensional liquid chromatography-mass spectrometry analysis method and system and the storage medium, simultaneous treatment and continuous analysis of a plurality of samples are realized, and the flux of sample analysis is improved.

The invention discloses a method for detecting formic acid, methanol and ethanol based on an automatic headspace gas chromatography-mass spectrometry technology. The detection method comprises the following steps: S1, preparing a mixed standard working solution of formic acid, methanol and ethanol; s2, adding an esterification reagent into the mixed standard working solution or the to-be-detected sample, and sealing the mixed standard working solution or the to-be-detected sample in a headspace bottle; s3, the headspace bottle is placed in an automatic headspace sampler, heating and heat preservation are conducted, formic acid and isopropanol are subjected to an esterification reaction to generate isopropyl formate, and meanwhile the isopropyl formate, methyl alcohol and ethyl alcohol are volatilized to the top space of the headspace bottle; s4, the headspace sample injector automatically extracts gas in the headspace and injects the gas into the gas chromatography system; and S5, carrying out separation through a chromatographic column, carrying out heating, carrying out detection by using a mass spectrometry detector, and carrying out qualitative and quantitative analysis on formic acid, methanol and ethanol in the to-be-detected sample. The detection method provided by the invention realizes rapid, automatic, high-sensitivity and high-specificity synchronous detection of formic acid, methanol and ethanol in a blood sample.

The utility model relates to the technical field of medicine packaging testing, in particular to a packaging system sealing performance testing device based on a helium mass spectrum, which comprises a low-temperature device, a sample testing device arranged in the low-temperature device and a helium mass spectrum detector, the sample testing device comprises an upper part and a lower part which is detachably arranged at the bottom of the upper part, wherein a first cavity is formed in the middle of the bottom of the upper part, first positioning holes are formed in the four corners of the top of the upper part respectively and penetrate through the upper part, first through holes are formed in the side wall of the upper part, and the first through holes communicate with the first cavity; according to the utility model, the sealing performance of the packaging system can be effectively detected in a low-temperature state, and powerful support is provided for medicine packaging quality control.

This invention belongs to the field of mass spectrometry detector technology, and specifically relates to a mass spectrometry detector and its data correction method, apparatus, and storage medium. The method includes: acquiring ion data collected by the mass spectrometry detector in scanning mode based on a preset scan step divided by ion mass; acquiring the actual mass of each group of ions of the same mass in the ion data and recording it as a data acquisition point, with each data acquisition point corresponding to a set acquisition point based on the preset scan step; when the mass difference between a data acquisition point and the corresponding set acquisition point is less than or equal to a preset accuracy range, using the signal intensity of the data acquisition point as the signal intensity of the corresponding set acquisition point; when the mass difference between a data acquisition point and the corresponding set acquisition point is less than or equal to a correction threshold, obtaining the signal intensity of the set acquisition point based on the signal intensities of the two data acquisition points with the closest masses to the corresponding set acquisition point. This improves the precision and accuracy of the acquired ion data.