57 results about "Ginsenoside-Re" patented technology

The invention discloses pediococcus acidilactici TH903 and application thereof in directional preparation of rare ginsenoside Rg4 by fermenting ginseng berries, and belongs to the field of fermentation engineering, the pediococcus acidilactici TH903 is preserved in the China Center for Type Culture Collection on September 29, 2025, the preservation number is CCTCC NO: M20252155, and the preservation unit is the China Center for Type Culture Collection. The Pediococcus acidilactici TH903 is utilized to successfully and directionally convert ginsenoside Re in the ginseng berry extract into rare ginsenoside Rg4, the rare ginsenoside Rg4 is mainly used as a fermentation product, the main target product, namely the rare ginsenoside Rg4, is accurately prepared, and the Pediococcus acidilactici TH903 has relatively high specificity, and can be used for preparing the rare ginsenoside Rg4. Meanwhile, the method has the advantages of high conversion efficiency and high conversion product content, and a cheap and efficient preparation process is established for the rare ginsenoside Rg4.

The invention relates to lactobacillus mucilaginosus and application thereof in preparation of ginsenoside F4, and belongs to the technical field of biotransformation of traditional Chinese medicinal materials. The technical problems that in the prior art, a biotransformation technology of rare ginsenoside F4 is insufficient in selectivity and environmental friendliness and high in cost are solved. The lactobacillus mucus disclosed by the invention is classified and named as LA729; the lactobacillus mucus is preserved in the China Center for Type Culture Collection (CCTCC) on August 4, 2025, and the preservation number of the lactobacillus mucus is CCTCC NO: M 20251765. The strain is safe in source and free of toxic and side effects, can secrete specific glycosidase in the fermentation process and selectively hydrolyze sugar residues on ginsenoside Re, so that structural reconstruction of the ginsenoside Re is achieved, target rare ginsenoside F4 is generated, selectivity is high, by-products are few, and the yield is stable.

The invention discloses a plant lactobacillus RET215 and application thereof in preparing rare ginsenoside by fermenting and converting ginsenoside Re, and belongs to the field of microbial fermentation, the plant lactobacillus RET215 is preserved in China Center for Type Culture Collection on May 21, 2024, and the preservation number is CCTCC NO: M20241024. The plant lactobacillus RET215 can be used for preparing rare ginsenosides 20 (R)-Rg2 and 20 (S)-Rg2 through fermentation and conversion by taking ginsenosides Re as a substrate. The method has the advantages of simple process, high conversion efficiency, high content of the obtained conversion product and the like, can ensure that the fermentation product takes 20 (R)-Rg2 and 20 (S)-Rg2 as main components, has higher specificity, and can be applied to ginseng deep processing products with unique requirements on ginsenosides 20 (R)-Rg2 and 20 (S)-Rg2.

The invention discloses application of notoginsenoside in preparation of a wound repairing medicine, and particularly discloses application of notoginsenoside in preparation of the wound repairing medicine. The notoginsenoside comprises ginsenoside Rb1, ginsenoside Re, ginsenoside Rg1 and notoginsenoside R1. The specific action mechanism of notoginsenoside in promoting wound healing is explored, and notoginsenoside is effectively applied to clinical practice, so that the current technical blank can be filled, and a new treatment way can be provided for wound repair, thereby benefiting the majority of patients.

The invention discloses a preparation method of 20 (E)-ginsenoside F4 and application of the 20 (E)-ginsenoside F4 in preparation of anti-liver injury medicines, and relates to the technical field of biological medicines. The rare ginsenoside 20 (E)-ginsenoside F4 is prepared and purified from ginsenoside Re through an acid catalytic conversion method, and the rare ginsenoside 20 (E)-ginsenoside F4 shows remarkable advantages and wide prospects in research and development of liver protection drugs. The monomer has strong liver protection activity, complies with the development trend of monomeric compound preparations, and provides efficient active ingredients for liver protection drugs. The 20 (E)-ginsenoside F4 with efficient activity, excellent safety and environment-friendly preparation characteristics can be widely applied to preparation of liver protection drugs or pharmaceutical compositions, especially drugs or pharmaceutical compositions for treating liver injury caused by chemotherapeutic drugs.

The present invention relates to the technical field of determination of ingredients in Chinese patent medicines, and in particular to a method for detecting ginsenoside content and an application thereof. The present invention utilizes a multiple heart-cutting two-dimensional liquid chromatography tandem charged aerosol detector method to detect the content of ginsenosides including notoginsenoside R1, ginsenoside Rg1, ginsenoside Re, 24(R)-pseudoginsenoside F11, ginsenoside Rf, ginsenoside Ra2, ginsenoside Rb1, ginsenoside Rg2, ginsenoside Rh1, ginsenoside Rc, ginsenoside Ro, ginsenoside Rb2, ginsenoside Rb3, ginsenoside Rd, ginsenoside Rg3(S), and ginsenoside Rg3(R). The method has the advantages of accuracy, high sensitivity, and strong specificity, is suitable for determining the content of ginsenosides in different Chinese patent medicines containing Panax genus Chinese medicines, and can be used reliably, comprehensively, and accurately for quality control of ginsenosides in Chinese patent medicines containing Panax genus Chinese medicines.

The invention discloses pediococcus acidilactici QM70-3 and application thereof in preparation of rare ginsenoside through fermentation conversion, and belongs to the field of probiotic fermentation, the pediococcus acidilactici QM70-3 is preserved in China Center for Type Culture Collection on February 25, 2025, and the preservation number is CCTCC NO: M 2025298. According to the invention, ginsenoside Re is used as a raw material, and the rare ginsenosides Rg2, Rg6, F4 and Rh1 are prepared by fermentation and conversion of pediococcus acidilactici QM70-3 capable of producing beta-glucosidase at high yield. After fermentation, the ginsenoside monomer Re can be completely converted into Rg2, Rg6, F4 and Rh1, and the technology does not need to depend on processes such as alkaline hydrolysis, high temperature and high pressure, steam treatment and the like, and has the characteristics of mild conditions, environmental friendliness, outstanding economical efficiency and the like. The invention provides a new way for the preparation of rare ginsenosides Rg2, Rg6, F4 and Rh1, and has a better application prospect.

The invention discloses lactobacillus mucus GB705 and application thereof in directional preparation of rare ginsenoside F4 by fermenting ginseng flower buds, and belongs to the field of fermentation engineering, and the preservation number of the lactobacillus mucus GB705 is CCTCC (China Center for Type Culture Collection) NO: M20252089. According to the invention, the lactobacillus mucus GB705 bacterial suspension is utilized to ferment the ginseng flower bud extract to prepare the rare ginsenoside F4, ginsenoside Re in the ginseng flower bud extract can be efficiently and directionally converted into the rare ginsenoside F4 only through one-step standing fermentation, multi-step reaction is not needed, the preparation process is simplified, the process complexity is reduced, and the method is suitable for industrial production. The raw material conversion rate and the yield of the rare ginsenoside F4 are improved. Meanwhile, in the standing fermentation process, the content of by-products is low, the solvent consumption is small, the conditions are mild, and large-scale and low-cost production of the rare ginsenoside F4 can be achieved.

The invention discloses plant lactobacillus BT810 and application thereof in preparing rare ginsenoside by fermenting ginseng flower buds, and belongs to the field of fermentation engineering. The lactobacillus plantarum BT810 is preserved in the China Center for Type Culture Collection on August 18, 2025, and the preservation number of the lactobacillus plantarum BT810 is CCTCC (China Center for Type Culture Collection) NO: M20251845. According to the method, a ginseng flower bud aqueous extract is taken as a fermentation substrate and inoculated with phytobacterium plantarum BT810 for standing fermentation, and ginsenoside Re in the ginseng flower bud aqueous extract is selectively hydrolyzed by beta-glucosidase secreted by the BT810 and is directionally converted into Rg2 and Rg4. The method has the advantages of extremely low by-products, high conversion rate, mild reaction conditions, low preparation cost and easiness in expanded production, and a convenient way is provided for large-scale, low-cost and efficient co-preparation of the rare ginsenosides Rg2 and Rg4.

A Pediococcus acidilactici QM70-3 and its application in the fermentative conversion for preparing rare ginsenosides belong to the field of probiotic fermentation. The Pediococcus acidilactici QM70-3 was deposited at the China Center for Type Culture Collection on February 25, 2025, with the deposit number of CCTCC NO: M 2025298. In the present invention, ginsenoside Re is used as the raw material, and the rare ginsenosides Rg2, Rg6, F4 and Rh1 are prepared by fermentative conversion using Pediococcus acidilactici QM70-3 with high β-glucosidase activity. After fermentation, the ginsenoside monomer Re can be completely converted into Rg2, Rg6, F4 and Rh1. This technology does not rely on processes such as alkali hydrolysis, high temperature and high pressure, and steam treatment, and has the characteristics of mild conditions, environmental friendliness and outstanding economy. The present invention provides a new way for the preparation of rare ginsenosides Rg2, Rg6, F4 and Rh1, and has good application prospects.

The invention relates to a construction method of a fingerprint spectrum of Shenxiong Tongmai capsule, which comprises the following steps: dissolving a ferulic acid standard substance, a hesperidin standard substance, a ginsenoside Re standard substance, a neohesperidin standard substance and a naringin standard substance in methanol to prepare a mixed reference substance solution; the method comprises the following steps: respectively dissolving contents of Shenxiong Tongmai capsules in a plurality of batches in a methanol aqueous solution to prepare a plurality of test solutions; respectively carrying out high performance liquid chromatography detection on the mixed reference substance solution and the plurality of test sample solutions to obtain a high performance liquid chromatogram of the mixed reference substance solution and high performance liquid chromatograms of the plurality of test sample solutions; determining characteristic peaks and identifying chemical components of the characteristic peaks, and calculating relative retention time of other characteristic peaks by taking the characteristic peak corresponding to hesperidin as a reference peak to obtain the fingerprint spectrum. The fingerprint spectrum obtained by the construction method disclosed by the invention can well reflect information of a plurality of index components of the Shenxiong Tongmai capsule.

The present application relates to a ginsenoside composition for inhibiting tyrosinase activity, which comprises any two or any three of ginsenoside Rd, ginsenoside Re or ginsenoside Rf. Ginsenoside Rf can be used as a synergistic molecule of ginsenoside Rd and Re, and can significantly enhance the inhibitory ability of tyrosinase activity through synergistic effect, thereby reducing the synthesis and secretion of melanin.

The invention discloses a quality detection method for Hailong Gejie oral liquid, which belongs to the technical field of Chinese medicine component detection, and includes a method for measuring the content of ginsenoside Rg1, ginsenoside Re, ginsenoside Rf and ginsenoside Rb1 by high performance liquid chromatography-mass spectrometry and / or a method for measuring the content of baicalin and / or a thin layer chromatography identification method for Polygonum multiflorum. The quality detection method for Hailong Gejie oral liquid provided by the present invention measures the content of ginsenoside Rg1, ginsenoside Re, ginsenoside Rf and ginsenoside Rb1 in Hailong Gejie oral liquid by high performance liquid chromatography-mass spectrometry, measures the content of baicalin by high performance liquid chromatography, and identifies Polygonum multiflorum by thin layer chromatography; the detection method provided has good accuracy, stability and repeatability, and can more effectively and comprehensively detect, evaluate and control the quality of Hailong Gejie oral liquid, and ensure the quality and clinical effect of the product.

This invention discloses a PDRN ginsenoside system and its preparation method, belonging to the field of cosmetics and topical skin preparations. Addressing the shortcomings of existing skincare products containing PDRN and ginsenosides, such as easy inactivation of active ingredients, low co-encapsulation rate of the two components, poor transdermal absorption efficiency, insufficient system stability and compatibility, and lack of synergistic effects, this invention designs a ginsenoside system composed of a phase A lipid carrier, a phase B aqueous matrix, and a phase C functional adjuvant. The proportions of each component are optimized, and a corresponding preparation process is provided. This invention achieves efficient co-loading of water-soluble PDRN and lipid-soluble ginsenosides, improving system stability and transdermal bioavailability of active ingredients, while also providing synergistic repair and anti-aging effects. It is gentle and non-irritating, and the preparation process is suitable for large-scale industrial production, making it widely applicable in various skincare formulations.

The invention relates to the technical field of skin care compositions, in particular to a ginsenoside composition gel soap liquid capable of doubly residing on skin. The composition does not contain a surfactant and a foaming agent, takes a panaxoside composition in a specific proportion as a core active component, and cooperates with a licorice extract, hyaluronic acid, a rapeseed extract, a bearberry leaf extract and a willow bark extract to form a stable gel system. The composition replaces traditional surfactants and foaming agents, solves the problems that traditional components damage skin barriers and cannot stay for a long time, has dual functions of deep cleaning and skin care, and has two characteristics of cleaning type non-staying products and cream type staying products at the same time. Experiments prove that the composition has excellent effects of resisting oxidation, whitening, deodorizing and removing cutin scales, is high in safety, does not contain harmful ingredients such as hormones and antibiotics, and can stay on the skin for a long time to play a continuous role.

The invention relates to the field of medicines, in particular to a composition, a preparation method of a pseudo-ginseng extract and application of the pseudo-ginseng extract. The composition is prepared from notoginsenoside R1, ginsenoside Rg1 and ginsenoside Re, and the weight ratio of the notoginsenoside R1 to the ginsenoside Rg1 to the ginsenoside Re is (2.05 to 2.5) to (7.5 to 9.4) to 1. The invention also provides application of the composition in preparation of drugs for preventing and / or treating cardiovascular and cerebrovascular diseases. The preparation method of the pseudo-ginseng extract provided by the invention comprises the following steps: cleaning pseudo-ginseng, removing impurities, pretreating, crushing, mixing with ethanol, soaking, percolating, collecting percolate, concentrating, and filtering to obtain the pseudo-ginseng extract. The composition provided by the invention can be used for effectively treating cardiovascular and cerebrovascular diseases, and can generate a better treatment effect compared with the existing composition adopting panaxatriol saponin.

The application discloses application of a glycosyltransferase Bs-YjiC in Bacillus subtilis 168 and comprises the following steps: catalyzing reaction of ginsenoside Rg2, the glycosyltransferase Bs-YjiC and uridine diphosphate glucose, so as to glycosylate C 20 hydroxyl group of the ginsenoside Rg2 to generate ginsenoside Re; or catalyzing reaction of notoginsenoside R2, the glycosyltransferase Bs-YjiC and uridine diphosphate glucose, so as to glycosylate C 20 hydroxyl group of the notoginsenoside R2 to generate notoginsenoside R1; the application utilizes the glycosyltransferase Bs-YjiC of microbial origin to catalyze C 20 hydroxyl group glycosylation of the ginsenoside Rg2 or the notoginsenoside R2, and since the ginsenoside Re and the notoginsenoside R1 have important pharmacological effects, the glycosyltransferase Bs-YjiC of microbial origin can be utilized to catalyze synthesis of the ginsenoside Re and the notoginsenoside R1 beneficial to human health.

The application belongs to the technical field of medicine, and particularly relates to a composition for alleviating and repairing testicular damage caused by heat stress and application thereof. The composition for alleviating and repairing testicular damage caused by heat stress comprises the following raw materials: lycopene inclusion compound, ginsenoside Re, modified chitosan nanoparticles and a solvent. The amount of the modified chitosan nanoparticles is 10-15 wt% of the ginsenoside Re. The application innovatively designs a combination formula with lycopene and ginsenoside Re as the core. Both of the two main effective components in the formula are natural plant or traditional Chinese medicine extract, which effectively avoids the conflict between the medicinal properties of traditional Chinese medicines and has good biological safety. The composition can significantly repair the testicular damage caused by heat stress and accelerate the recovery after heat stress damage.

The application discloses a kind of β-glucosidase GE000505 for saponin conversion and its preparation method and application, belong to biotechnology field, the amino acid sequence of the β-glucosidase GE000505 as shown in SEQ ID NO.1, it is encoded by the gene with nucleotide sequence as shown in SEQ ID NO.2.This β-glucosidase GE000505 of the application can convert high content ginseng and sanchi saponin into rare saponin R2, Rg3, Rg2 and Rh1, can convert sanchi saponin R1 into R2 entirely, convert ginsenoside Rd into Rg3 entirely, convert ginsenoside Re into Rg2 entirely, convert ginsenoside Rg1 into Rh1 entirely, convert ginsenoside F1 into aPPT entirely, convert ginsenoside F2 into aPPD entirely, solve the problem that existing β-glucosidase is not resistant to alcohol in the conversion of ginsenoside.

The invention relates to the technical field of health-care food, in particular to a pseudo-ginseng oral liquid and a preparation method and application thereof, and the pseudo-ginseng oral liquid comprises the following components in percentage by weight: 20-40% of pseudo-ginseng root extract, 3-8% of pseudo-ginseng stem and leaf extract, 0.5-2% of pseudo-ginseng flower extract and the balance of purified water. The total saponin is not less than 1200 mg / 100 mL in terms of ginsenoside Re, the ginsenoside Rb1 is not less than 30 wt%, the ginsenoside Rg1 is not less than 25 wt%, and the notoginsenoside R1 is not less than 5 wt%. The pH value of the product is 4.5-7.5, the product meets strict physicochemical and microbial standards, the product is packaged by a sodium-calcium glass bottle, and the shelf life is 24 months. The preparation method comprises the following steps: exclusively extracting, purifying, preparing, sterilizing and the like, and realizing quality controllability through an HPLC (High Performance Liquid Chromatography) characteristic chromatogram. The preparation is reasonable in dosage form, the problems of moisture absorption, low bioavailability and the like of a solid preparation are solved, and the active components are easy to absorb and convenient to take. Through research, the health-care tea has the health-care functions of improving hypoxia tolerance and relieving physical fatigue, and is suitable for people with related requirements.

The invention discloses an SNP (Single Nucleotide Polymorphism) molecular marker related to the content of ginsenoside Re in panax notoginseng and application, the SNP molecular marker is SNP10-13886209 and is located at the 13886209th basic group of Chr10 chromosome, and the mutation type of the SNP molecular marker is G / T. The KASP primer combination developed by the invention can accurately distinguish pseudo-ginseng with high ginsenoside Re content from pseudo-ginseng with low ginsenoside Re content, can be applied to pseudo-ginseng molecular-assisted marker breeding and shorten the breeding period of new varieties, and has the advantages of low detection cost, no environmental limitation, high detection result accuracy and easy repetition. The method has important theoretical and practical guiding significance for accelerating the genetic improvement process of panax notoginseng breeding with high ginsenoside Re content and improving the breeding selection efficiency.

The invention relates to the technical field of biological medicine, in particular to application of zinc-ginsenoside coordination nano-enzyme in treatment of diabetic nephropathy. The Zn (at) Gs-Re nano-enzyme provided by the invention not only enhances the stability and biological activity of ginsenoside Re, but also endows the ginsenoside Re with novel similar SOD / CAT enzyme activity, realizes multiple synergistic effects of resisting oxidation, resisting inflammation, resisting apoptosis, protecting mitochondria and improving renal functions, and shows remarkable superiority in the aspect of treating diabetic nephropathy and related complications.

The present application relates to the technical field of compound analysis, and in particular to a quality analysis method of ginseng medicinal materials, comprising the following steps: S100, preparation of a control solution: taking ginsenoside Rg1 control product, ginsenoside Re control product, ginsenoside Rf control product, ginsenoside Rb1 control product, ginsenoside Rc control product, ginsenoside Rb2 control product, ginsenoside Rd control product, 3-O-feruloylquinic acid control product, 4-coumaric acid control product, 8-O-4 / 8-O-4 dehydrogenated tri-ferulic acid control product, and adding methanol to prepare a mixed solution, and shaking to obtain the control solution. The present application synchronously monitors two components of saponins and phenolic acids under one detection method, monitors ten component contents of seven saponin components and three polyphenol components, obtains characteristic spectra of saponin components and polyphenol components, and the monitoring quality is more comprehensive and efficient.

The invention discloses a preparation method of 20 (Z)-ginsenoside F4 and application of the 20 (Z)-ginsenoside F4 in preparation of anti-liver injury medicines, and relates to the technical field of biological medicines. The rare ginsenoside 20 (Z)-ginsenoside F4 is prepared and purified from ginsenoside Re through an acid catalytic conversion method, and the rare ginsenoside 20 (Z)-ginsenoside F4 shows remarkable advantages and wide prospects in research and development of liver protection drugs. The monomer has strong liver protection activity, complies with the development trend of monomeric compound preparations, and provides efficient active ingredients for liver protection drugs. The 20 (Z)-ginsenoside F4 with efficient activity, excellent safety and environment-friendly preparation characteristics can be widely applied to preparation of liver protection drugs or pharmaceutical compositions, especially drugs or pharmaceutical compositions for treating liver injury caused by chemotherapeutic drugs.

The invention relates to the technical field of detection, in particular to a method for detecting the ginsenoside component of a nephritis-relieving tablet, the contents of ginsenoside Rg1, ginsenoside Re and ginsenoside Rb1 in the nephritis-relieving tablet are simultaneously determined by adopting a liquid chromatography-mass spectrometry method, and the method comprises the following steps: (1) preparing a test solution; (2) setting liquid chromatography conditions; (3) setting mass spectrum conditions; the invention establishes a liquid chromatography-mass spectrometry method for simultaneously determining three ginsenoside components in the nephritis-relieving tablet, and the method has the advantages of simple and convenient sample treatment process, short analysis time (only 4.5 min), high sensitivity, high specificity and the like. Compared with the content determination item of the nephritis-relieving tablet in 2020 edition Chinese Pharmacopoeia, the content determination of the characteristic component ginsenoside Rb1 of ginseng is increased, and a reference can be provided for the overall quality control and evaluation of the nephritis-relieving tablet.

The invention relates to the technical field of compound analysis, in particular to a quality analysis method of a ginseng medicinal material. Comprising the following steps: S100, preparation of a reference substance solution: taking a proper amount of a ginsenoside Rg1 reference substance, a ginsenoside Re reference substance, a ginsenoside Rf reference substance, a ginsenoside Rb1 reference substance, a ginsenoside Rc reference substance, a ginsenoside Rb2 reference substance, a ginsenoside Rd reference substance, a 3-O-feruloylquinic acid reference substance, a 4-coumaric acid reference substance and an 8-O-4 / 8-O-4 dehydrotriferulic acid reference substance; and adding methanol to prepare a mixed solution, and uniformly shaking. According to the method, the saponin and phenolic acid components are synchronously monitored under one detection method, the contents of ten components including seven saponin components and three polyphenol components are monitored, the specific chromatograms of the saponin components and the polyphenol components are obtained, and the monitoring quality is more comprehensive and efficient.

The application provides a multi-component quantitative analysis method of anti-aging tablets, acetonitrile-0.1% formic acid aqueous solution is used as a mobile phase, an HSS T3 chromatographic column is used for target compound separation, and 13 active components in the anti-aging tablets are simultaneously determined in an MRM mode by using an electrospray ionization triple quadrupole mass spectrometer, the linear range of the 13 active components is 0.4-100 ng / mL, the linear range of ginsenoside Rb1, ginsenoside Rb2, ginsenoside Rc, ginsenoside Rd, ginsenoside Re, ginsenoside Rf and ginsenoside Rg1 is 4-1000 ng / mL, the method has high sensitivity, strong specificity and good reproducibility, and realizes simultaneous quantitative analysis of the 13 active components in the anti-aging tablets.

The invention relates to the technical field of biotechnology, in particular to an extraction and filtration method of ginseng fruit total saponin powder, which specifically comprises the following steps: sequentially carrying out water extraction, pH value regulation, centrifugation, purification, concentration, drying, crushing and mixing on ginseng fruit pulp, and finally extracting to obtain the ginseng fruit total saponin powder with the yield of 0.76-0.80%. The concentration of ginsenoside Re in the ginseng fruit total saponin powder is not lower than 650 mg / g, the concentration of microorganism aerobic bacteria is smaller than or equal to 800 cfu / g, the concentration of mould and saccharomycetes is smaller than or equal to 80 cfu / g, and no Escherichia coli is detected, so that the validity period of the ginseng fruit total saponin powder is greatly prolonged and can reach 36 months in a sealed and moistureproof environment.

There are described compositions comprising an effective amount of a combination of two or more components, said components selected from acacetin, ACTI peptide, alpha-lipolic acid, alprostadil, anisomycin, apigenin, ascorbic acid, astragalus, berberine, β-lapachone, β-hydroxy-beta-methyl-butyrate, Bacopa monnieri, catechin, catechol, chamomile, chrysin, coumestrol, curcumin, dinitrophenol, dinoprost, ellagic acid, (−)-epigallocatechin gallate, green tea extract, fisetin, genistein, ginsenoside RE, glabridin, 18-α-glycyrrhetinic acid, 18-β-glycyrrhetinic acid, glycyrrhizin, hydroquinone, isoquercitrin (EMIQ), kaempferol, kuromanin, leucine, lithium, luteolin, luteolin, luteolinidin, melatonin, menadione, 1-methylnicotinamide (MNA), methyl salicylate, myricetin, nadide, niacin (vitamin B3), nicotinamide (NAM), nicotinamide mononucleotide (NMN), nicotinamide riboside (NR), nicotinic acid adenine dinucleotide (NaAD), nicotinic acid mononucleotide (NaMN), parsley (Petroselinium crispum), phenylephrine, pokeweed mitogen, 15-Δ prostaglandin J2, puromycin, quercetin, quinolinic acid, retinoic acid, trichostatin A, troxrutin, rutin, tryptophan, vitamin D3, withaferin A, wortmannin and zinc (including salts thereof).

The present invention discloses an anti-aging Chinese herb extract, an extraction method and a use thereof. The ginseng-Astragalus membranaceus extract of the present invention comprises 20 to 30% of astragaloside, 1 to 5% of ginsenoside Rg1, 2 to 6% of ginsenoside Re, 0.2 to 0.5% of ginsenoside Rb1. There are 17 characteristic peaks in high-performance liquid chromatography fingerprints of the extract. The extract can effectively improve activity of telomerase, delay cell aging, and can be applied to preparation of an anti-aging product.