Houkangsan quality control method

Abstract

The invention provides a method for controlling the quality of a Chinese traditional throat medicine. The method comprises the steps: (1) discriminating ginseng, radix trichosanthis and liquorice contained in the Chinese traditional throat medicine by the microscope discrimination method; (2) detecting vitriol in natrii sulfas exsiccatus by the barium chloride reagent precipitation method; (3) detecting natural indigo in the Chinese traditional throat medicine by the thin-layer chromatography, and comparing the natural indigo with indigotin and indirubin; (4) detecting borneol and menthol by the thin-layer chromatography; (5) detecting ginseng contained in the Chinese traditional throat medicine by the thin-layer chromatography, and comparing the Chinese traditional throat medicine with ginseng, ginseng saponin Rb1, ginsenoside Re and ginsenoside Rg1; (6) detecting liquorice contained in the Chinese traditional throat medicine by the thin-layer chromatography; and (7) detecting the content of andrographolide and dehydrolyzed andrographolide contained in the Chinese traditional throat medicine. The method used for controlling the quality of the Chinese traditional medicine overcomes the defects of the prior discrimination method that the specificity is not enough; the thin-layer chromatography is used for detecting natural indigo, borneol and menthol simultaneously, the sampling amount is difficult to grasp, and excellent separating effect is difficult to reach, the thin-layer chromatography can just detect limited ingredients, i.e. natural indigo, borneol and menthol, thus failing to effectively discriminate the Chinese traditional throat medicine; the prior discrimination method fails to measure the content of effective ingredients, and can not effectively control the defects of product quality. The method improves the specialty and the quality stability, and ensures security and effective use of the medicine by users.

Description

technical field [0001] The invention relates to a quality control method of Chinese patent medicines, in particular to a quality control method of Houkang Powder. Background technique [0002] Houkang San is a Chinese patent medicine for clearing heat, detoxifying, reducing inflammation and relieving pain. It has been used in my country for many years and is clinically used for various throat diseases, such as acute and chronic pharyngitis, laryngitis, tonsillitis, oral ulcers, etc. Houkang powder is prepared from borneol, nacre powder, ginseng, borax (calcined), xuanming powder, menthol, trichosanthes powder, Qingdai, Andrographis paniculata leaves, and licorice according to the conventional process of Chinese patent medicine powder. This standard is recorded in the Ministry of Health of the People's Republic of China Drug Standards Chinese Medicine Prescriptions Volume 5, Standard No. WS 3 -B-1040-91. The identification methods in this standard include: (1) microscopic i...

AI Technical Summary

Problems solved by technology

Wherein experiment (3) specificity is not strong, implementation (4) thin-layer chromatography exists the shortcoming that point sample volume is difficult to grasp and reach better separation effect; Wherein, when point sample volume is large, the separation effect of menthol, borneol is poor , when the sample amount is small, the spots of indigo and ind...