The invention belongs to the field of analysis of traditional Chinese medicine preparations, and particularly discloses a quality detection method of Shouhui Tongbian capsule. The method comprises thefollowing steps: identifying polygonum multiflorum in the Shouhui Tongbian capsule by thin-layer chromatography; on the basis of a high performance liquid chromatography technology, detecting the content of 2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucoside, naringin, neohesperidin, barbaloin A, barbaloin B, aloe-emodin and chrysophanol in the Shouhui Tongbian capsule is determined by adopting aone-standard multi-measurement analysis method and 2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucoside as an internal reference substance. The quality detection method is simple and convenient to operate, stable and reliable, strong in specificity and good in reproducibility, can comprehensively and effectively control the quality of the aloe vera bowel relaxing capsules, is beneficial to stabilizing the product quality, and ensures the safety and effectiveness of clinical medication, thereby better meeting the requirements of medical treatment and markets.