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74results about How to "Guaranteed curative effect" patented technology

Quality control method of traditional Chinese medicine preparation based on Icanteobagrus fulvidraco orifice-dredging formula

The invention discloses a quality control method of a traditional Chinese medicine preparation based on an IV-catfish orifice-freeing prescription, and relates to the technical field of analysis of traditional Chinese medicine preparations, and the quality control method comprises the following steps: carrying out microscopic identification on traditional Chinese medicine components in the IV-catfish orifice-freeing prescription, and determining a pharmacodynamic material basis. According to the quality control method for the traditional Chinese medicine preparation based on the IVV orifice-freeing prescription, various evaluation means such as a drug effect equivalent evaluation index, a stability test, a quality test and a clinical test are comprehensively applied, the consistency and reliability of the curative effect of the traditional Chinese medicine preparation can be remarkably improved, and the drug effect equivalent evaluation index is analyzed from the two factors of drug effect intensity and action time; the method ensures the equivalence of the medicinal component group and the original traditional Chinese medicine preparation, comprehensively detects the raw material medicines and the preparation, including characters, identification, inspection and content determination items, and ensures that the quality of each batch of samples meets the standard, so that the curative effect of the traditional Chinese medicine preparation is effectively guaranteed, and the efficacy of the traditional Chinese medicine preparation is improved.
Owner:JILIN ACAD OF TRADITIONAL CHINESE MEDICINE

Nano-drug delivery system for targeting neutrophil as well as preparation method and application of nano-drug delivery system

The invention relates to a nano-drug delivery system targeting neutrophil and a preparation method and application thereof. The nano-drug delivery system is prepared by the following method: S1, preparing a liposome 1 wrapping a drug 1; s2, preparing a liposome 2 wrapping a medicine 2; and S3, mixing and incubating the liposome 1 wrapping the medicine 1 and the liposome 2 wrapping the medicine 2, and connecting the corresponding ligand and receptor in the liposome 1 and the liposome 2 to obtain the liposome. The ligand and the receptor are respectively biotin and streptavidin. The nano-drug delivery system is obtained by successfully connecting two drug liposomes with different functions through a ligand and a receptor system, so that the chemotaxis of neutrophil to an infected part can be enhanced, the antibacterial property of NETs can be improved, and the nano-drug delivery system has a very good anti-infection effect.
Owner:SUN YAT SEN UNIV

White peony root extract for treating hyperuricemia, preparation method and application thereof

The present invention belongs to the field of medical technology related to the extraction and application of natural drug components, discloses a white peony extract for treating hyperuricemia, a preparation method thereof and an application thereof, and provides a preparation method of a white peony extract for treating hyperuricemia, wherein the obtained white peony extract has a good therapeutic effect on a hyperuricemia animal model; mainly inhibiting uric acid production by inhibiting the activity of xanthine oxidase in serum and liver, while downregulating the levels of renal tissue proteins URAT1 and GLUT9, and upregulating the levels of renal tissue proteins OAT1 and OAT3 to reduce uric acid reabsorption and promote uric acid excretion, thereby achieving the purpose of reducing uric acid levels. Furthermore, the white peony extract is synergistically used with the currently commonly used uric acid-lowering drug allopurinol to develop a more effective and safe uric acid-lowering treatment plan.
Owner:ANHUI XIEHECHENG PHARM TABLET CO LTD

Intelligent eye medicine box and control method thereof

The invention relates to the technical field of intelligent eye medicine boxes, and discloses an intelligent eye medicine box and a control method thereof.The eye medicine box is divided into a plurality of compartments for storing different types of medicine, and a sensor is arranged in each compartment to detect the weight of the medicine in real time; and accurately calculating the residual amount of the medicine by combining the initial weight data of the medicine, the dosage of the medicine currently used by the user, the last time of using the medicine by the user, the weight of the medicine in the last time and the total number of times of using the medicine by the user. Furthermore, the future drug use dosage and use rate are predicted through a machine learning model, the remaining amount is optimized based on the prediction results and the real-time weight data, the optimized remaining amount is obtained, and the optimal remaining amount is calculated according to the optimized remaining amount and the future drug use rate. Specifically, firstly, the accuracy of medicine management is remarkably improved through a smoke and flame identification method, it is ensured that a patient can use medicine on time according to the amount, and the poor treatment effect caused by missed taking or wrong taking is avoided;
Owner:BEIJING TONGREN HOSPITAL AFFILIATED TO CAPITAL MEDICAL UNIV

Anti-inflammatory, antibacterial, itching-relieving and skin-moistening compound composition and preparation method thereof

The invention discloses an anti-inflammatory, antibacterial, itching-relieving and skin-moistening compound composition and a preparation method thereof, and relates to the field of medicines. Comprising the following components in parts by weight: 0.5-2 parts of chlorhexidine acetate, 5-15 parts of radix sophorae flavescentis, 2-8 parts of Chinese prickly ash, 3-10 parts of folium artemisiae argyi, 4-12 parts of cortex phellodendri, 2-6 parts of cortex pseudolaricis, 3-9 parts of fructus kochiae, 1-5 parts of cortex dictamni, 1-4 parts of rhizoma atractylodis, 1-4 parts of radix saposhnikoviae, 2-6 parts of fructus cnidii, 1-5 parts of radix cynanchi paniculati, 0.5-2 parts of borneol, 5-15 parts of aloe and 10-30 parts of propylene glycol. 5-15 parts of tea oil and 1-5 parts of herba violae; according to the anti-inflammatory, antibacterial, itching-relieving and skin-moistening compound composition and the preparation method thereof, various Chinese herbal medicine components are carefully screened and scientifically proportioned, so that the compound composition can remarkably inhibit growth of bacteria and fungi and effectively relieve skin inflammation response, and meanwhile, the excellent itching-relieving and skin-moistening effects are shown.
Owner:HENGYANG AIMINKANG BIOTECHNOLOGY CO LTD

Method for preparing NMN hydrogel microcapsule based on ionic gelation technology

The invention relates to a method for preparing an NMN hydrogel microcapsule based on an ionic gelation technology, which comprises the following steps: taking an NMN solution as an active molecule solution, respectively carrying out ionized cross-linking reaction on a cationic hydrogel polymer and an anionic hydrogel polymer under the triggering action of a cationic cross-linking agent, and embedding NMN in a hydrogel film layer to form the NMN hydrogel microcapsule. The NMN hydrogel microcapsule prepared by the method has excellent slow-release performance, the particle size of the prepared microcapsule is uniform, the whole preparation process is green and environment-friendly, an organic solvent and a heating reaction are not needed, and natural and nontoxic cationic hydrogel polymer and anionic hydrogel polymer are selected as materials for preparing a hydrogel film layer, so that the hydrogel film layer is more stable in performance. And the hydrogel has good biocompatibility and biodegradability, is harmless to a human body and is high in safety.
Owner:BEIJING XUTANG BIOTECHNOLOGY CO LTD

Visual management intelligent medicine box and system for children medication and use method of visual management intelligent medicine box and system

The invention relates to a child medication visual management intelligent medicine box and system and a use method thereof, medication management is performed on children in a welfare hospital, and visualization, intelligence and safety of child medication management are achieved through the Internet of Things, artificial intelligence and big data technologies. The medicine taking reminding function and the intelligent voice reminding function are visual, the medicine taking compliance of children is effectively improved, and the medicine taking safety and the curative effect of the children are guaranteed. Due to the remote monitoring and management function, the workload of nursing personnel is relieved, and the nursing personnel can put more time and energy into nursing and education of children. Medicine management optimization and safety guarantee functions are achieved, missing taking, wrong taking or unauthorized taking of children are effectively prevented, and the medication safety of the children is guaranteed. By collecting and analyzing medicine taking data of children, the intelligent medicine box can provide data analysis and decision support for nursing personnel, help the nursing personnel to optimize medicine taking management strategies and improve the health level of the children.
Owner:TAIZHOU CENT HOSPITAL

Iron maltol crystal form DCIII as well as preparation method and application thereof

The invention relates to a crystal form of a compound I, a preparation method of the crystal form, and application of the crystal form in preparation of iron deficiency related treatment medicines for treating anemia accompanied with or not accompanied with iron deficiency. The novel crystal form of the compound I provided by the invention has the advantages of high solubility, good chemical stability, solid stability, mechanical stability and humidity stability, simple preparation method, easiness in crystal form control, low production amplification cost and the like, and has important value for development of the medicine in the future. # imgabs0 #
Owner:BIRDO (SHANGHAI) PHARM R&D CO LTD

Fingerprint spectrum construction method and application of traditional Chinese medicine composition containing angelica sinensis and cinnamon

The invention discloses a fingerprint spectrum construction method of a traditional Chinese medicine composition containing angelica sinensis and cinnamon. The construction method comprises the following steps: preparing a test solution; preparing a reference substance solution; and obtaining the fingerprint spectrum of the traditional Chinese medicine composition according to results of high performance liquid detection of the test solution and the reference solution. The chemical components of the traditional Chinese medicine composition containing angelica sinensis and cinnamon are comprehensively and systematically analyzed, and a theoretical basis is provided for deep research on quality control and pharmacodynamic material basis.
Owner:HUNAN YINENG BIOLOGICAL PHARMA

Furosemide micro-tablet and preparation method thereof

The invention discloses a furosemide micro-tablet preparation and a method for preparing the furosemide micro-tablet, furosemide, an adhesive, a diluent and other raw materials are subjected to top spray fluidized bed granulation and other preparation methods to prepare the furosemide micro-tablet with good compressibility, the furosemide micro-tablet can be dosed for multiple times in a small dosage, and the furosemide micro-tablet preparation can be used for preparing the furosemide micro-tablet. Especially for people with large individual metabolism difference, such as old people and infants, the medicine can be taken in a counting manner and is accurately administered, for people with difficulty in taking conventional preparations, the medicine taking compliance can be improved, and the method and the raw materials used by the invention are convenient for industrial production.
Owner:BEIJING KEXIN JURUN PHARM TECH CO LTD

Hydrochlorothiazide micro-tablet and preparation method thereof

PendingCN119112811Aeasy to swallowGuaranteed curative effectOrganic active ingredientsCapsule deliveryHydrochlorothiazideMultiple administration
The invention discloses a novel hydrochlorothiazide dosage form and a method for preparing the novel hydrochlorothiazide dosage form, the novel hydrochlorothiazide dosage form with good compressibility is prepared from hydrochlorothiazide, an adhesive, a filling agent and other raw materials through top spray fluidized bed granulation and other preparation methods, and the novel hydrochlorothiazide dosage form has the advantages that the novel hydrochlorothiazide dosage form has obvious curative effect on patients suffering from edema, hypertension and diabetes insipidus; according to the present invention, the pharmaceutical composition can be subjected to multiple administration at a small dose, can be subjected to counting administration especially for people with large individual metabolism difference, such as old people and children, can achieve accurate administration, can improve the medication compliance for people with difficulty in taking conventional preparations, and has characteristics of simple method, easily available raw materials, and easy industrial production.
Owner:BEIJING KEXIN JURUN PHARM TECH CO LTD

Gynecological antibacterial gel for female HPV (human papilloma virus) and preparation process thereof

The invention discloses gynecological antibacterial gel aiming at female HPV (human papillomavirus) and a preparation process thereof. The gynecological antibacterial gel is prepared from the following raw materials in parts by weight: 1 to 5 percent of compound fungal polysaccharide, 0.1 to 1 percent of herba centellae extract, 0.1 to 1 percent of coriolus versicolor extract, 0.1 to 1 percent of green tea extract, 0.1 to 0.8 percent of fucoidan polysaccharide sulfate and 0.1 to 1 percent of ginsenoside rg3. The preservative is prepared from, by weight, 0.1%-1% of ginsenoside rg2, 0.1%-1% of betulin, 0.1%-0.5% of sophora flower bud extract, 0.1%-1% of natural silkworm antibacterial peptide, 0.5%-1% of carbomer, 0.1%-0.2% of chlorhexidine gluconate, 3% of glycerinum, 0.6% of xylooligosaccharide, 0.6% of sodium hyaluronate middle molecules, 1.5% of hydrolyzed beta-glucan, 0.6% of 98% D-panthenol, 0.6% of provitamin B5, 0.3% of vitamin C, 0.3% of sodium ascorbate and the balance deionized water. The invention relates to the technical field of gynecological treatment. The composition contains various natural plant extracts and bioactive components, can effectively improve cervical health, can realize effective integration of a microemulsion system and a water phase system during preparation, forms a uniform and stable final product, protects the active components, and ensures the curative effect and product performance.
Owner:智昱铭

Traditional Chinese medicine composition for dispelling effects of alcohol as well as preparation method, application and product of traditional Chinese medicine composition

The invention belongs to the field of traditional Chinese medicine compositions, and particularly relates to a sobering and hangover alleviating traditional Chinese medicine composition which comprises a component A and a component B, wherein the component A comprises a component a, a component b, a component c and a component d; the component B comprises a component e, a component f, a component g and a component h; in the component A, the component a is radix puerariae and an extract thereof; the component b is rhizoma polygonati and an extract thereof; the component c is poria cocos and an extract thereof; the component d is lily and an extract thereof; in the component B, the component e is radix ophiopogonis and an extract thereof; the component f is fructus lycii and an extract thereof; the component g is konjak and an extract thereof; the component h is orange peel and an extract thereof. The eight medicines are combined and can realize synergism, and excellent sobering and hangover alleviating effects can be obtained. The traditional Chinese medicine composition disclosed by the invention can have better sobering and hangover alleviating functions on the basis of the combined action of multiple mechanisms of metabolism acceleration, organ protection and system conditioning, and the components in the traditional Chinese medicine composition all belong to safe raw materials with homology of medicine and food.
Owner:MEDONCARE PHARMA CO LTD

Disposable cervical HPV (human papillomavirus) photodynamic automatic therapeutic apparatus

The invention provides a disposable cervical HPV (human papilloma virus) photodynamic automatic therapeutic apparatus which comprises a cervical cover for applying medicine and performing light treatment and an insertion main body connected with the cervical cover, a light-emitting element is arranged on the end face, facing the illumination direction, of the cervix uteri cover, a cone made of light-transmitting materials is arranged outside the light-emitting element, and a medicine film is attached to the outside of the cone. At least one part of the cervical cover is made of a light-transmitting material, and the at least one part is a part between the light-emitting element and the vertebral body, so that light emitted by the light-emitting element can be transmitted to the vertebral body in a barrier-free manner; and moreover, one side, opposite to the illumination direction, of the cervical cover is connected to the insertion main body through a connecting shaft, so that the cervical cover and the insertion main body can relatively rotate through the connecting shaft.
Owner:BEIJING YINGGUANG AUTOMATION TECHNOLOGY CO LTD

Feeding structure for filling brightening capsule particles

The utility model relates to a feeding structure for filling brightening capsule particles in the field of pharmacy, which comprises a feeding funnel, a metering valve seat and a control mechanism, an upper valve block and a lower valve block are arranged in the metering valve seat in a sliding mode, an upper valve hole and a lower valve hole are formed in the middle of the upper valve block, a material supplementing hole is formed in the top of an upper valve cavity, and a feeding hole is formed in the bottom of a lower valve cavity. A metering hole is vertically and coaxially formed between the upper valve cavity and the lower valve cavity, and the upper valve hole and the lower valve hole are alternately communicated with the metering hole; the feeding funnel is connected with a feeding hole of the metering valve seat; the capsule seat is rotationally butted below the feeding hole of the metering valve seat in sequence; the control mechanism comprises a stepping motor and a cam shaft, upper and lower cams opposite in direction are eccentrically mounted on the upper and lower portions of the cam shaft and slidably abut against the upper and lower valve blocks correspondingly, and an upper pressure spring and a lower pressure spring are correspondingly arranged on the right sides of the upper and lower valve blocks. The feeding structure can more accurately control and adjust the filling metering of granular medicine in a single capsule, and the quality and the curative effect of a finished product of the brightening capsule are ensured.
Owner:ZHENGZHOU FURUITANG PHARMA

Traditional Chinese medicine composition for treating pressure sores as well as oil yarn product and application thereof

The invention discloses a traditional Chinese medicine composition for treating pressure sores and an oil yarn product and application thereof, and the traditional Chinese medicine composition is characterized by being prepared from the following raw material medicines in parts by weight: 80-120 parts of lithospermum, 40-60 parts of golden cypress, 40-60 parts of scutellaria baicalensis, 40-60 parts of astragalus membranaceus, 30-50 parts of prepared frankincense, 30-50 parts of prepared myrrh and 15-25 parts of pseudo-ginseng powder. The preparation method comprises the following steps: adding sesame oil into a pot, boiling with big fire, turning off the fire, cooling for 1-2 minutes, sequentially adding radix arnebiae seu lithospermi, cortex phellodendri, radix scutellariae, radix astragali, prepared frankincense and prepared myrrh, after all the medicines are completely immersed into the sesame oil, boiling with slow fire for 4-5 minutes, turning off the fire, removing residues, filtering, finally adding pseudo-ginseng powder, and fully stirring and uniformly mixing to obtain the oil preparation for treating the skin ulcers. Use is convenient, and clinical popularization significance is high.
Owner:DAISHAN COUNTY TRADITIONAL CHINESE MEDICINE HOSPITAL

Medicine for treating heart failure and subclinical hypothyroidism by combining traditional Chinese medicine and western medicine

The invention belongs to the technical field of traditional Chinese medicine, and discloses a medicine for treating heart failure and subclinical hypothyroidism through combination of traditional Chinese medicine and western medicine, and the in-hospital agreement prescription comprises 10 g of radix aconiti lateralis preparata, 15 g of bighead atractylodes rhizome, 10 g of honey-fried licorice root, 15 g of earthworm, 6 g of red ginseng, 30 g of astragalus membranaceus, 10 g of cassia twig, 20 g of salvia miltiorrhiza, 12 g of angelica sinensis, 15 g of fructus amomi, 15 g of radix paeoniae rubra, 10 g of almond, 15 g of pericarpium arecae, 30 g of semen plantaginis, 12 g of polyporus umbellatus, 15 g of poria cocos, 15 g of fried semen lepidii, 12 g of rhizoma alismatis and 10 g of jujube. The yang-strengthening and foundation-consolidating decoction is combined with western medicines to treat patients suffering from heart failure and subclinical hypothyroidism, the clinical signs of the patients are obviously improved, the heart function and the thyroid function are obviously improved after the patients are subjected to the traditional Chinese and western medicine combined therapy for a period of time, and compared with the patients only treated by the western medicines, the treatment effect of the traditional Chinese and western medicine combined therapy is better. At present, no adverse reaction is found temporarily, so that the medicine has no obvious toxic and side effects, is high in safety and moderate in price, and is worthy of clinical popularization and application.
Owner:MIN COUNTY HOSPITAL OF TRADITIONAL CHINESE MEDICINE

Wearable medicine curative effect monitoring equipment

The invention relates to the technical field of drug curative effect monitoring, in particular to wearable drug curative effect monitoring equipment which comprises a wearable garment, two arm sleeves are fixedly connected to the upper portion of the wearable garment, a micro monitoring controller is arranged on one side of the left arm sleeve, and a monitoring operation box is connected to the upper surface of the micro monitoring controller. A blood collecting unit is arranged on the right side of the interior of the monitoring operation box and comprises a linkage box movably arranged in the monitoring operation box, a sealing hole plate is arranged on one side of the linkage box, a sealing piece is slidably arranged on the upper portion of the sealing hole plate in an inserted mode, and a collecting hopper is fixedly connected to the right side of the linkage box; two extraction suction pipes are arranged at the upper end of the collection hopper, so that when a patient goes out, the effect of the medicine in the body can be regulated, controlled and monitored, the overall medicine curative effect is judged in cooperation with comprehensive monitoring of saliva and urine, and the overall medicine curative effect monitoring effect and efficiency are guaranteed.
Owner:YICHUN CITY FIRST HOSPITAL (YICHUN CITY CHILDRENS HOSPITAL)

Application of Peiyuan Gubenfang in reducing the toxicity of adjuvant chemotherapy after radical resection of non-small cell lung cancer

PendingCN122075648AImprove postoperative frailtyImprove weak constitutionAntinoxious agentsRespiratory disorderAdenophora strictaWolfiporia extensa
This invention belongs to the field of traditional Chinese medicine technology, specifically relating to the application of a formula for nourishing vital energy and strengthening the body in reducing the toxicity of adjuvant chemotherapy after radical resection of non-small cell lung cancer. This invention discloses a formula for nourishing vital energy and strengthening the body, characterized in that it is composed of the following components by weight: 15-30 parts raw Astragalus membranaceus, 9-21 parts prepared Rehmannia glutinosa, 15-30 parts stir-fried Dioscorea opposita, 9-15 parts Atractylodes macrocephala, 9-15 parts Poria cocos, 15-30 parts raw Coix lacryma-jobi, 9-15 parts Ophiopogon japonicus, 9-15 parts Asparagus cochinchinensis, 15-30 parts Adenophora stricta, 9-15 parts Ligustrum lucidum, 9-15 parts Eclipta prostrata, 9-15 parts stir-fried germinated barley, 9-15 parts stir-fried malt, and 3-6 parts prepared Glycyrrhiza uralensis. This invention can restore vital energy, reverse postoperative weakness, build a foundation for chemotherapy tolerance to reduce toxic side effects, improve chemotherapy tolerance, reduce the risk of interruption to ensure efficacy, improve quality of life during chemotherapy, and help prolong postoperative survival.
Owner:SHANGHAI PULMONARY HOSPITAL (SHANGHAI OCCUPATIONAL DISEASE PREVENTION & CONTROL INSTITUTE)

Percutaneous puncture balloon device giving consideration to trigeminal nerve meniscus and third branch compression

The percutaneous puncture balloon device comprises a catheter, the outer side wall, close to the operation end, of the catheter is provided with an inner-layer balloon, and the inner-layer balloon is sleeved with an outer-layer balloon; the catheter comprises a catheter body of a hollow structure, the interior of the catheter body is divided into an upper cavity and a lower cavity through a partition plate, the side wall face of the upper cavity is provided with an inner ventilation opening communicated with the inner-layer balloon, and the side wall face of the lower cavity is provided with an outer ventilation opening communicated with the outer-layer balloon. A rotary cavity switching mechanism is arranged at the end, away from the balloon, of the partition plate and used for switching between the upper cavity and the lower cavity. The inner-layer balloon comprises a balloon body, and an elastic binding film layer is arranged in the middle of the balloon body. The traditional Chinese medicine composition has the characteristic of effectively improving the curative effect of a patient suffering from pain in the third branch area.
Owner:HANGZHOU FIRST PEOPLES HOSPITAL

Application of polydocanol in preparation of medicine for treating lymphatic leakage

The invention belongs to the technical field of medicines, and relates to application of polydocanol in preparation of a medicine for treating lymphatic leakage through a drainage tube or direct puncture application, and the polydocanol is a polydocanol foaming agent. The poly-docanol foaming agent is prepared by rapidly sucking and mixing a liquid preparation containing 5-30 mg of poly-docanol per milliliter and sterile air for 30 times through a three-way cock according to the volume ratio of 1: (1-5), wherein the volume ratio of the liquid preparation to the sterile air is 1: (1-5); the lymphatic leakage is armpit lymphatic leakage caused after breast cancer operation. The invention also provides a treatment method for applying the polydocanol in the lymphatic leakage patient and a medicine for treating the lymphatic leakage, and the medicine comprises the polydocanol and pharmaceutically acceptable auxiliary materials. The method has the advantages of small trauma, simplicity and convenience in operation, high safety, short treatment period, quick response and the like.
Owner:SHANGHAI NINTH PEOPLES HOSPITAL SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE

Fingerprint of a kidney-tonifying and hair-blackening oral liquid, construction method and application thereof, and multi-index component detection method of the kidney-tonifying and hair-blackening oral liquid

This invention provides a fingerprint spectrum of Yishen Wufa Oral Liquid, its construction method, and its application, as well as a multi-index component detection method for Yishen Wufa Oral Liquid, relating to the field of pharmaceutical analysis and structural technology. The fingerprint spectrum of Yishen Wufa Oral Liquid constructed by this invention includes 20 characteristic peaks, including ferulic acid, 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside, astragaloside A, psoralen, isopsoralen, and emodin. The chromatographic peaks are abundant and attributed to the effective components of psoralen (roasted with black sesame seeds), angelica, poria cocos, wolfberry, fleeceflower root (processed with black bean wine), achyranthes bidentata, and astragalus complanatus. This provides a more comprehensive reflection of the overall chemical composition and quality of Yishen Wufa Oral Liquid, facilitating more effective guidance for feed addition and strict standardization of production operations. It also helps improve the safety and efficacy of Yishen Wufa Oral Liquid in clinical use, possessing high application value.
Owner:CHANGCHUN UNIV OF CHINESE MEDICINE

Traditional Chinese medicine composition for treating primary sicca syndrome complicated with interstitial lung disease and application thereof

The invention provides a traditional Chinese medicine composition for treating primary sicca syndrome complicated with interstitial lung disease and application of the traditional Chinese medicine composition, and relates to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the following traditional Chinese medicine raw materials in parts by weight: 10-15g of radix glehniae, 10-15g of radix ophiopogonis, 15-30g of radix pseudostellariae, 10-20g of curcuma zedoary, 6-12g of roasted stiff silkworm and 15-30g of wild buckwheat rhizome. The traditional Chinese medicine composition can safely and effectively improve the respiratory function, dry mouth, dry eye and other symptoms of pSS-ILD patients, improve the life quality of the patients and delay the disease progression, has no obvious side effect, and is simple in formula and low in cost.
Owner:NANJING UNIV OF TRADITIONAL CHINESE MEDICINE

A detection method of Baizhu San standard decoction fingerprint combined with liquid chromatography-mass spectrometry, fingerprint and application thereof

ActiveCN117825565BExclusiveStrong specificity
The application discloses a detection method of Baizhu San standard decoction fingerprint combined with liquid chromatography-mass spectrometry, the fingerprint and application thereof, and belongs to the field of traditional Chinese medicine quality standard research and application. Test sample solution and single control sample solution are injected into a high performance liquid chromatograph to obtain respective chromatograms; mass spectrometry analysis is conducted on the test sample solution to obtain mass spectrometry results; common peaks existing in the chromatogram of the test sample solution are taken as common peaks, chemical components in the Baizhu San standard decoction are identified in combination with the chromatogram of the single control sample solution and the mass spectrometry results of the test sample solution, and the Baizhu San standard decoction fingerprint is obtained. The fingerprint is constructed through liquid chromatography-mass spectrometry, 10 intersecting components are identified in combination with the mass spectrometry information of the control sample, so that the quality control of the Baizhu San standard decoction is realized, the method is simple, easy to operate, high in precision, good in stability and reproducibility, and can effectively solve the technical problem that the quality of the Baizhu San cannot be effectively evaluated.
Owner:SHAANXI UNIV OF SCI & TECH

Hydrochlorothiazide micro-tablet and preparation method thereof

PendingCN119112810Aeasy to swallowGuaranteed curative effectOrganic active ingredientsCapsule deliveryHydrochlorothiazideMultiple administration
The invention discloses a hydrochlorothiazide micro-tablet preparation and a method for preparing hydrochlorothiazide micro-tablets, the hydrochlorothiazide micro-tablets with good compressibility are prepared from hydrochlorothiazide, an adhesive, a filling agent and other raw materials through top-spraying fluidized bed granulation and other preparation methods, and the hydrochlorothiazide micro-tablets have the advantages that the hydrochlorothiazide micro-tablets have no toxic or side effects on patients suffering from edema, hypertension and diabetes insipidus; according to the present invention, the pharmaceutical composition can be subjected to multiple administration at a small dose, can be subjected to counting administration especially for people with large individual metabolism difference, such as old people and children, can achieve accurate administration, can improve the medication compliance for people with difficulty in taking conventional preparations, and has characteristics of simple method, easily available raw materials, and easy industrial production.
Owner:BEIJING KEXIN JURUN PHARM TECH CO LTD

A fingerprint construction method of a traditional Chinese medicine composition containing Atractylodes macrocephala and its application

The present invention discloses a method for constructing a fingerprint of a Chinese medicine composition containing Atractylodes macrocephala, and the method comprises the following steps: preparing a test solution of the Chinese medicine composition; preparing a reference solution; and obtaining a fingerprint of the Chinese medicine composition according to the results of high performance liquid phase detection of the test solution of the Chinese medicine composition and the reference solution. The present invention comprehensively and systematically analyzes the chemical components of the Chinese medicine composition containing Atractylodes macrocephala, and provides a theoretical basis for in-depth research on quality control and the material basis of drug efficacy.
Owner:HUNAN YINENG BIOLOGICAL PHARMA

A fingerprint construction method of a traditional Chinese medicine composition containing Belamcanda chinensis and Ephedra sinica and its application

The present invention discloses a method for constructing a fingerprint of a Chinese medicine composition containing Belamcanda chinensis and Ephedra sinica, and the method comprises the following steps: preparing a test solution of the Chinese medicine composition; preparing a reference solution; and obtaining a fingerprint of the Chinese medicine composition according to the results of high performance liquid phase detection of the test solution of the Chinese medicine composition and the reference solution. The present invention comprehensively and systematically analyzes the chemical components of the Chinese medicine composition containing Belamcanda chinensis and Ephedra sinica, and provides a theoretical basis for in-depth research on quality control and the material basis of drug efficacy.
Owner:HUNAN YINENG BIOLOGICAL PHARMA

Suspension high-shear dispersion preparation mixing equipment

The utility model aims to provide suspension high-shear dispersion preparation mixing equipment which comprises a dispersion machine, a stirring disc is arranged at the bottom of a main shaft, and the stirring disc comprises a second dispersion disc positioned at the bottom end of the main shaft, and a middle guide paddle and a first dispersion disc which are positioned above the second dispersion disc. The utility model relates to the technical field of mixing equipment, and adopts a multi-stirring impeller which combines a first dispersion disc and a second dispersion disc and is provided with a middle guide paddle between the first dispersion disc and the second dispersion disc, so that the stirring mode of a traditional single rectangular tooth dispersion impeller is changed; and the solution is rolled to the upper part by the second dispersion disc to be in contact with the first dispersion disc for secondary shearing. After secondary shearing, the particle size can be further refined, and the distribution is more uniform, so that the dissolution speed and bioavailability of the medicine are improved, and the curative effect of the medicine is ensured. Compared with the traditional equipment that the single-time stirring time is more than 15 minutes, the equipment disclosed by the utility model can obviously reduce the single-time stirring time.
Owner:LIAONING DAEWOONG PHARMA CO LTD

Preparation method of florfenicol composite medicine

ActiveCN119523915AThere are few types of usesimplified treatment planOrganic active ingredientsAntibacterial agentsSulfated polysaccharidesPharmaceutical Substances
The invention discloses a preparation method of a florfenicol composite drug, and belongs to the technical field of pharmaceutical preparations, the preparation method comprises the following steps: adding florfenicol into a chitosan solution, and attaching the florfenicol to chitosan to form a precursor compound; then an arthrospira sulfated polysaccharide extract is added into the precursor compound, due to the binding force between the arthrospira sulfated polysaccharide extract and chitosan, composite particles coated with florfenicol are formed, and the arthrospira sulfated polysaccharide extract is located on the periphery of the composite particles, so that the composite particles are hydrophilic and carry negative charges; the composite particles coated with the florfenicol are the florfenicol composite medicine. According to the scheme, the use variety of drugs is reduced, the compound drug integrates multiple treatment functions into one drug, the variety of drugs needing to be taken by a patient at the same time is reduced, and the treatment scheme is simplified. According to the scheme, the florfenicol hydrogel has the characteristics of biocompatibility and degradability, the water solubility of florfenicol is improved, the reaction process is very simple, and the florfenicol hydrogel is suitable for industrial production.
Owner:ZHEJIANG KANGMU PHARMA

Warehouse intelligent management system and method based on cloud computing

The invention discloses a warehouse intelligent management system and method based on cloud computing, and relates to the technical field of warehouse intelligent management, and the system comprises a data collection module, an influence analysis module, an analysis set establishment module, a comparison analysis module and an early warning module. And the data acquisition module is used for acquiring information, including physical information and system information, during operation of the temperature sensor in the medicine storage, and transmitting the physical information and the system information to the influence analysis module after acquisition. According to the invention, the influence condition of the detection precision of the temperature sensor for medicine storage is monitored, and when the detection precision of the temperature sensor is abnormal, a worker is prompted to check the temperature sensor in time, so that the curative effect and the treatment effect of a medicine are guaranteed, and the treatment effect and the safety of a patient are further guaranteed; and intelligent and efficient management of medicine storage is realized.
Owner:SHENZHEN NUOFEI TECH DEV CO LTD