The invention relates to a method suitable for industrial production of memantine hydrochloride. 1,3-dimethyl adamantane is used as a starting material, and a Ritter reaction, hydrolysis, salt forming and refining are used for preparing; during the Ritter reaction, acetonitrile is directly used as an acetylation reagent, concentrated sulfuric acid is used as a catalyst and a solvent, and the reaction is carried out at 70-80 DEG C; after the reaction ends, water is directly added into ice water, dichloromethane is used for extraction and drying by distillation, n-hexane is used for recrystallization, and 1-acetamido-3, 5-dimethyladamantane is directly obtained by one step; 1-acetamido-3, 5-dimethyladamantane is hydrolyzed under an alkaline condition in order to obtain 1-amino-3, 5-dimethyladamantane, a memantine crude product is obtained by salt forming of 1-amino-3, 5-dimethyladamantane under the condition of dichloromethane solvent acidifying, water is used as a solvent in order to carry out recrystallization of the crude product, and a refined product is obtained. In the first acetyl amination process, concentrated sulfuric acid is used as a catalyst and a solvent, tedious industrial post-treatment due to usage of anhydrous aluminium chloride as a catalyst is avoided, an extractant employs dichloromethane, in order to avoid usage of chloroform of high toxicity, and recrystallization employs water as a solvent with environmental protection and cost saving.