50results about How to "Extended release time" patented technology

The invention provides a fiber dressing for promoting wound healing and a preparation method and application thereof, and belongs to the technical field of biological materials. The shell of the fiber dressing contains the first medicine for promoting polarization of macrophages, and the first medicine can promote polarization of macrophages at normal and diabetic wound surfaces from M1 type to M2 type; a shell substrate is a mixture of hydrophilic and hydrophobic polymers, so that painless adhesion and stripping of a wound surface can be realized by absorbing seepage and spraying non-irritant normal saline on the wound surface, and secondary injury of the wound surface is reduced; an inner core contains a second medicine and a third medicine which are used for inducing death of M1 type macrophages, so that wound inflammatory response can be reduced, wound bacteria can be killed, wound infection degree can be reduced, and wound healing can be accelerated; the core matrix is a mixture of hydrophilic and hydrophobic polymers with good biocompatibility, can provide mechanical support for the fiber dressing, and provides a slow release effect for the two substances in the core. By controlling the composition of the inner core and the shell, the healing of normal wounds and diabetic wounds can be effectively promoted.

The invention belongs to the technical field of biological medicine, and relates to hydrogel for promoting wound healing and a preparation method and application thereof.The preparation method comprises the steps that firstly, coriander exosomes are extracted from coriander through a gradient centrifugation and sucrose density gradient method, then the coriander exosomes and a sodium alginate solution are mixed according to the mass-to-volume ratio of 0.5-2 mg: 1 mL, and a hydrogel solution is obtained; and mixing the exosome suspension with a calcium chloride solution according to a volume ratio of (0.5-2): 1, and carrying out crosslinking to obtain the coriander exosome-loaded hydrogel. The coriander exosome-loaded novel hydrogel provided by the invention has good viscoelasticity and biocompatibility, and can be applied to the surface of a skin wound as a dressing; meanwhile, the hydrogel has a coriander exosome slow-release effect, so that the exosome release time is prolonged, and the biological function is better played; by slowly releasing the coriander exosome, the hydrogel can relieve oxidative stress and inflammation of wounds and promote wound repair.

The invention belongs to the field of drug preparation, and particularly relates to a preparation method and application of a drug delivery system based on hollow mesoporous polydopamine nanoparticles. The drug delivery system comprises hollow mesoporous polydopamine nanoparticles, a drug loaded inside and / or outside the hollow mesoporous polydopamine nanoparticles, and pectin wrapping the hollow mesoporous polydopamine nanoparticles, the medicine is a medicine with a nerve protection effect and an acetylcholin esterase inhibitor. The drug delivery system can reduce proinflammatory cytokines, regulate functions of target immune cells, synergistically reduce necrosis of neurons in intestinal tracts and induce neural crest stem cells in the intestinal tracts to be differentiated into neurons.

According to the antibacterial and antioxidant composite film applied to food preservation and the production method of the antibacterial and antioxidant composite film, the chlorogenic acid, the catechin, the montmorillonite and the zeolite are introduced, and a drying process is optimized, so that the antibacterial performance, the antioxidant performance and the mechanical performance of the preservative film are remarkably improved, and meanwhile, the water vapor permeability and the oxygen permeability are reduced. The method comprises the specific steps of raw material preparation, polyphenol compound and mineral substance preparation, membrane liquid preparation and treatment, drying process optimization and finished product membrane uncovering. According to the preparation method disclosed by the invention, components such as chlorogenic acid, catechin, montmorillonite and zeolite are introduced, and a drying process is optimized, so that the food preservative film with synergistic antibacterial and antioxidant properties is prepared.

The present invention relates to the field of fresh-keeping technology, and in particular to a fruit, vegetable and flower fresh-keeping package. The fruit, vegetable and flower fresh-keeping package is prepared from the following components: sodium chlorite, a modified activator, an ethylene inhibitor and auxiliary materials, wherein the modified activator is obtained by encapsulating an organic acid activator with sulfonated β-cyclodextrin and then encapsulating chitosan. The fruit, vegetable and flower fresh-keeping package provided by the present invention realizes efficient and long-term fresh-keeping of fruits, vegetables and flowers, and has broad market potential and application prospects.

According to the euphausia superba oil jelly and the preparation method and application thereof, euphausia superba oil and walnut oil are combined, nutritional ingredients which are rich in Omega-3 fatty acid, EPA, DHA and the like and beneficial to brain health can be provided for consumers, choices of different hardness and elasticity are achieved through the reasonable proportion of gelidium amansii powder and water, and the euphausia superba oil jelly has the advantages of being good in taste, good in taste and good in taste. The low-sugar low-calorie jelly has the advantages that the low-sugar low-calorie low-calorie jelly meets the taste requirements of consumers of different age groups such as children and old people, in addition, erythritol is adopted as a sweet source, the sugar content of the jelly is effectively controlled, the calorie intake is reduced, the low-sugar low-calorie low-calorie low-calorie low-calorie low-calorie low-calorie low-calorie low-calorie low-calorie low-calorie low-calorie low-calorie low-calorie the release time of nutritional ingredients in a digestive system can be prolonged, and the absorption efficiency of nutrients is further improved, so that perfect combination of delicious taste, functions and health is realized.

The invention relates to the technical field of animal feed, in particular to pet food easy to digest and absorb and a preparation process thereof. The preparation process comprises the following steps: preparing a chitin nanofiber suspension; preparing a modified pork liver protein solution; preparing a digestion-aiding additive; the pet food easy to digest and absorb is prepared. Maleic anhydride is grafted on pork liver protein, so that the solubility of the pork liver protein in water is improved, the pork liver protein is easier to disperse, the pork liver protein is rich in high-quality protein, for pets, the excessive high-quality protein is not easy to absorb, but overnutrition occurs, and after the pork liver protein is grafted with maleic anhydride, the surface property of the protein is changed, so that the pet nutrition is improved. The modified pork liver protein solution is added, the biological absorptivity can be better improved, the content of protein in the modified pork liver protein solution can be reduced due to introduction of maleic anhydride, the content of protein in the prepared pet food is within the range capable of being absorbed by pets, and the prepared pet food is easy to digest and absorb.

The invention relates to a cigarette essence blasting bead and a preparation method thereof, and belongs to the technical field of essence blasting bead preparation. The prepared hollow mesoporous nano silicon dioxide has a very stable structure, heat resistance and pH value change resistance, the essential oil embedding advantage of the hollow mesoporous nano silicon dioxide is that the hollow cavity provides a storage space for the essential oil, and the hollow mesoporous nano silicon dioxide serving as an inorganic material has higher mechanical strength compared with a high-molecular polymer material, so that the hollow mesoporous nano silicon dioxide can be used for preparing essential oil. Essential oil effective component leakage caused by capsule breakage in the storage process can be prevented, and the retention property, durability and stability of the essential oil are improved; secondly, due to the fact that the pore diameter of mesopores is 2-20 nm, the microcapsule has excellent slow release performance on essence or essential oil, loading and releasing are difficult due to the fact that the pore diameter is too small, and due to the fact that the pore diameter is too large, the microcapsule is inevitably interfered by the external environment more easily, and the slow release performance and the stability of the microcapsule are too poor, and therefore the slow release performance and the stability of the microcapsule are too poor due to the introduction of the mesoporous nano-silica; the slow release performance of the capsule wall material is improved.

The invention discloses magnesium-based hydrogen-rich bone cement as well as a preparation method and application thereof. The magnesium-based hydrogen-rich bone cement is prepared by mixing and curing powder and curing liquid, the powder comprises the following components in parts by mass: 50-80 parts of structural powder, 10-15 parts of a bonding consumable, 5-10 parts of a healing accelerant and 15-40 parts of an auxiliary agent, the structural powder comprises reinforcing powder and compatible powder, the reinforcing powder comprises at least one of calcium silicate and calcium phosphate, and the compatible powder comprises at least one of magnesium silicate and magnesium phosphate; the healing accelerant comprises a biodegradable polymer and a magnesium-based material embedded in the biodegradable polymer; and after the powder and the curing liquid are mixed and cured, surface activation treatment is applied, and at least part of the bonded consumables are removed. The magnesium-based hydrogen-rich bone cement disclosed by the invention can be applied to preparation of bone defect repair materials, can relieve local tissue inflammatory response, and is high in oxidation resistance, long in oxidation resistance duration, few in organic residues on the ceramic surface of the bone cement and good in biocompatibility.

The invention discloses a preparation method of a photo-thermal energy storage super-hydrophobic all-weather anti-icing coating. The preparation method comprises the following steps: step 1, preparing long afterglow nanoparticles; step 2, performing in-situ modification on a double-shell microcapsule phase change material by using the long afterglow nanoparticles; step 3, performing low surface energy modification treatment on composite particles; according to the anti-icing coating prepared by the invention, icing is delayed by virtue of a super-hydrophobic surface formed by the super-hydrophobic micro-nano structure particles; solar energy is efficiently converted into heat energy through the photo-thermal material, ice is prevented instantly, and residual heat is stored in the phase-change material; the long-afterglow material is used for storing sunlight for night photo-thermal conversion, and the stored heat released by the phase-change material is combined to jointly realize night long-acting ice prevention and removal; all-weather effective anti-icing is achieved through a multi-layer anti-icing mechanism, the problem that an existing coating is poor in all-weather anti-icing / deicing effect under the low-temperature and high-humidity condition is solved, and the coating has important application prospects in the anti-icing field of power transmission lines, aircraft wings and the like.

The invention discloses a soil-improving, water-retaining and fertility-increasing coating material as well as a preparation method and application thereof, aiming at the obstacle attributes that sandy soil in a desertification region is poor in water-retaining and fertilizer-retaining capacity and loose in structure, hydrochloric acid acidified nano clay and a citrus peel extract are self-assembled to obtain a coating liquid, and then ionic crosslinking is performed to obtain an excellent fertilizer. The gain effect of the coating material on the growth promoting effect of plants in the desertification region is comprehensively evaluated through tests such as texture, controlled release, water retention and potting experiments; the potential influence of the coating material on the human body and the environment is comprehensively judged through a cytotoxicity test, life cycle evaluation and a soil biodegradation experiment. The novel citrus peel extract-nano clay coating material prepared by the method provided by the invention overcomes the application limitation of traditional coated fertilizers, and can effectively reduce the transportation loss of urea fertilizers, improve the release efficiency of urea, increase the water-retaining property and structural stability of soil and promote the growth of plants in regions with severe environments such as desertification.

This invention relates to the field of pulse circuit technology and discloses a high-efficiency AC power line zero-crossing detection chip, including a path selection module, a signal processing module, and a driving module. The path selection module switches the charging circuit according to the potential of the internal power supply capacitor. The signal processing module uses a feedback loop to adjust the switching level of the sampling branch and generate a zero-crossing trigger pulse signal. The driving module responds to the zero-crossing trigger pulse signal by segmentally turning on the internal power supply capacitor and the external energy supply capacitor in the initial and subsequent stages of the zero-crossing point. This invention solves the contradiction between the ultra-high input impedance sampling environment and the driving strength through a controlled hysteresis window and a segmented current injection mechanism, suppresses signal jitter, improves the timing accuracy of zero-crossing detection, and effectively reduces the static power consumption of the system.

The invention discloses an engineered cell intraocular transplantation device based on a hyaluronic acid scaffold, the engineered cell intraocular transplantation device comprises a vitreous body and a cell intraocular transplantation device fixed in the vitreous body, the cell intraocular transplantation device comprises engineered cells, a hyaluronic acid hydrogel scaffold and a suture sclera; according to the engineered cell storage container of the capsule-shaped structure, a semi-permeable polymer film is adopted, the semi-permeable film is provided with gaps of 15 nm, engineered cells wrapped by hyaluronic acid hydrogel are arranged in the semi-permeable film, the bottom of the semi-permeable film is a sealed end, and a detachable sealing end cover is arranged at the top end of the semi-permeable film; the sealing end is used for preventing invasion of an eye immune system; and the sealing end cover is sealed by using a medical-grade sealant, so that the cells are prevented from being invaded by host immune cells. The invention provides a new technical solution for the field of protection and transplantation of engineered cells, and shows remarkable economical efficiency, practicability, safety, operation convenience and stability.

The invention discloses an insect trapping plate containing pheromone-urea resin microcapsules. The insect trapping plate comprises colored body paper or a fiber material, a barrier release layer containing the pheromone-urea resin microcapsules and insect sticking glue, the barrier layer containing the pheromone-urea resin microcapsule is prepared from 1 to 3 parts of pheromone, 95 to 97 parts of urea resin and 1 to 3 parts of an emulsifier; wherein the pheromone is composed of a plurality of components selected from trans-2-hexenal, 1-pentene-3-alcohol, violet ketone, linalool, cis-3-hexene-1-alcohol, and phenoxyethanol, and the pheromone is composed of a plurality of components selected from the group consisting of 2-hexenal, 1-pentene-3-alcohol, violet ketone, linalool, cis-3-hexene-1 The urea-formaldehyde resin is urea-formaldehyde resin jointly modified by melamine and polyvinyl alcohol. The invention further provides a preparation method of the insect trapping plate containing the pheromone-urea resin microcapsules. The insect trapping plate provided by the invention releases pheromones in a long-acting manner, and the insect trapping effect is lasting; and after being buried, the fertilizer can be used as a fertilizer to provide nitrogen necessary for growth of crops.

The invention discloses a drug-loaded liposome based on colon targeting and a preparation method thereof, and belongs to the technical field of nano targeting drugs, the drug-loaded liposome sequentially comprises an active ingredient inner core, a chitosan interlayer and a sodium alginate shell layer from inside to outside; the preparation method comprises the following steps: preparing an active ingredient core solution; under a stirring condition, dropwise adding the active ingredient core solution into the chitosan solution, and continuously stirring after dropwise adding to obtain an active ingredient-chitosan solution; the preparation method comprises the following steps: dropwise adding an effective component chitosan solution into a sodium alginate solution under a stirring condition, and continuously stirring after dropwise adding is finished, so as to obtain the chitosan-sodium alginate hydrogel. The lipidosome is stable in structure in the stomach and the small intestine and high in gastric acid damage resistance, the targeting property of the medicine in the colon can be effectively improved, the utilization rate of the medicine is increased, and the problem that the content of effective components, acting on the colon, of an existing medicine is low is solved.

The invention discloses a potassium sulfate fertilizer and a marking method thereof. The marking method comprises the following steps: S1, mixing rubidium sulfate and potassium sulfate powder to obtain a mixed reagent; s2, preparing the rubidium sulfate and potassium sulfate mixed reagent into a saturated solution; s3, heating and evaporating the saturated solution to obtain marked potassium sulfate fertilizer particles. The physical and chemical properties of the obtained marked potassium sulfate fertilizer test product are similar to those of the existing potassium sulfate fertilizer, replacement of fertilizer application can be realized, a soil potassium source and a fertilizer potassium source can be distinguished, the absorption and utilization effects of crops on different potassium sources are further determined, and a more reliable method is provided for reasonable application of the potassium fertilizer.

The invention relates to a preparation technology of a camptothecin derivative targeted long-acting liposome. Firstly, a long-acting liposome with a targeting function is prepared, folic acid is modified on the surface of the liposome to realize an active targeting function, a metal copper ion and triethanolamine system is used for increasing the drug loading ratio of the liposome, and then the drug loading ratio and the photo-thermal performance of the camptothecin derivative are enhanced by utilizing the pi-pi conjugation effect of the camptothecin derivative and indocyanine green. The long-acting liposome prepared by the invention is uniform in particle size distribution and good in dispersity, can effectively protect a camptothecin lactone ring from being hydrolyzed and inactivated, prolongs the half-life period and stability of a medicine, and effectively solves the problems of poor water solubility, high toxicity, low bioavailability and the like of camptothecin. The prepared targeted long-acting liposome has a targeting property on folate receptor overexpressed tumor cells, further improves the anti-tumor effect of the drug, reduces the toxic and side effects on normal cells, can be applied to targeted therapy of the anti-tumor drug, and has a good application prospect.

The invention discloses a preparation method and application of nano sponge hydrogel loaded with alkannin. Beta-cyclodextrin and a BTDA cross-linking agent are subjected to cross-linking reaction through esterification reaction to prepare cyclodextrin nano sponge with a porous structure, and alkannin is stably loaded in the cyclodextrin nano sponge through subject-object interaction; the loading capacity of the alkannin can be improved, the slow release effect of the alkannin can be improved, and the drug release time can be prolonged; according to the present invention, the shikonin is used as a main body and is combined with the gel formed by the QCS and the PVA, and the adhesion with the skin is increased by using the high-viscosity hydrogel, such that the long-time pasting on the skin can be used, the slow release effect can be further improved, the shikonin bioavailability can be improved, the treatment effect can be improved, the drug use frequency can be easily reduced, and the secondary injury of the wound can be avoided; the wound healing can be better promoted. The preparation method disclosed by the invention is simple to operate and low in cost, has good stability and biocompatibility, and can remarkably improve the capability of promoting wound healing.

The invention discloses a slow-release dressing for local surface long-acting anesthesia and a preparation method of the slow-release dressing, and belongs to the technical field of anesthesia dressings. The preparation method of the slow-release dressing for local surface long-acting anesthesia is used for solving the technical problems that in the prior art, the slow-release rate of an anesthesia dressing cannot be adjusted according to the tolerance of a patient to anesthetics, and the duration time of the anesthesia dressing needs to be further prolonged. Comprising the following steps: uniformly coating skin-friendly base cloth with anesthesia sustained-release gel to form an anesthesia sustained-release layer on the skin-friendly base cloth; coating the top of the anesthesia sustained-release layer with composite gel to form a water-absorbing and moisturizing layer; laying an antibacterial non-woven fabric on the top of the water-absorbing and moisture-preserving layer to obtain a primary anesthetic dressing product. The anesthesia sustained-release gel and the composite gel are matched with each other, so that the duration time of the anesthesia dressing is effectively prolonged, the release rate of the anesthetic in the anesthesia dressing can be adjusted according to the tolerance of a patient to the anesthetic, and the anesthesia effect of the anesthesia dressing is improved.

The invention relates to the technical field of pharmaceutical preparations. The invention provides a drug-loadable liposome and a preparation method thereof, and the preparation method comprises the following steps: (1) mixing lecithin, dipalmitoyl phosphatidylcholine, cholesterol and an organic solvent, and carrying out ultrasonic dissolution to obtain a phase A; (2) mixing polyoxyethylene sorbitan monostearate with a phosphate buffer solution to obtain a phase B; and (3) adding the phase A prepared in the step (1) into the phase B prepared in the step (2), stirring, evaporating, and filtering to obtain the product. The liposome prepared from the raw materials and the technical scheme is more stable in performance, better in drug loading stability and higher in drug entrapment capacity, and the drug release time can be prolonged.

The present invention relates to the field of animal feed technology, and in particular to a pet food that is easily digestible and absorbable and a preparation process thereof. The preparation process comprises the following steps: preparing a chitin nanofiber suspension; preparing a modified pig liver protein solution; preparing a digestive aid additive; and preparing a pet food that is easily digestible and absorbable. The present invention improves the solubility of pig liver protein in water and makes it easier to disperse by grafting maleic anhydride onto pig liver protein. Pig liver protein is rich in high-quality protein. For pets, excessive high-quality protein is not easy to absorb, but will result in overnutrition. After pig liver protein is grafted with maleic anhydride, the surface properties of the protein are changed, which can better improve the absorption rate of organisms. In addition, the introduction of maleic anhydride can reduce the protein content in the modified pig liver protein solution, so that the protein content in the prepared pet food is within the range that the pet can absorb, and the prepared pet food is easy to digest and absorb.

The present invention relates to the field of mosquito repellent technology, and discloses a heterojunction mosquito repellent composite material based on plant extracts and its preparation method and application, including: N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride and N-hydroxysuccinimide are dissolved in anhydrous ethanol to obtain a mixture A; ZIF8 and polyethylene glycol are dissolved in a solvent to obtain a mixture B; Mixture A is added to mixture B, ultrasonic stirring is uniform, and it is continuously placed in an ultrasonic environment for 12-48h to obtain a mixture C; Bi2O3 powder is dissolved in an acid solution to obtain a mixture D, and mixture D is added to mixture C, ultrasonic stirring is uniform, and mixture E is obtained; Acorus calamus extract is added to mixture E, and after stirring, it is placed in a hydrothermal reactor for treatment; The product is centrifuged and washed to obtain a heterojunction mosquito repellent composite material. The present invention has a lasting mosquito repellent effect, has antibacterial and mildew-proof functions, is environmentally friendly and harmless to the human body.

The present application relates to a kind of gel type chlorine dioxide slow-release agent and its preparation method, to solve the defects of chlorine dioxide gas instability, short storage time of disinfectant product in prior art, the gel system of the present application includes: chlorite aqueous solution, gelling agent, graphene oxide, PH regulator and activator, the present application uses graphene oxide as chlorine dioxide gas regulator, utilizes the better adsorption performance of graphene oxide and its surface oxygen-containing functional group, synergistic effect with gelling agent, so that the reaction of chlorine dioxide gas is like a super micro chemical processing plant, establishes a "constantly evaporating, constantly replenishing" chlorine dioxide balance system, continuously releases chlorine dioxide gas, kills a variety of bacteria and viruses in air, purifies air, no secondary pollution, and low price.

The invention discloses a composite material for continuous lithium extraction based on photo-thermal synergy, a supercooled continuous lithium extraction method and application, and belongs to the technical field of salt lake lithium extraction and heat energy management. According to the prepared floating type photo-thermal synergistic lithium extraction composite material, through the design of a three-layer composite structure, the synergistic function of temperature regulation and control, lithium ion adsorption and structure supporting is achieved, the problems that a traditional lithium adsorption material is prone to sedimentation and usually needs an additional supporting structure are solved, the density is smaller than that of water, and the composite material can stably float on the surface of salt lake brine; and large-scale deployment and recovery are facilitated.

According to the energy storage cabinet electric core level fire extinguishing system and method, the structure is simple, the fire source is accurately aligned, the fire extinguishing agent spraying time is more accurate, and the continuous fire extinguishing time is longer. The system comprises a fire extinguishing medium storage device, a fire detection tube, a composite detector, a trigger and a controller, wherein the controller is in communication connection with a system background; the fire-fighting method of the system comprises the following steps: a, when a combustion factor is detected, the controller controls the system to stop; b, the composite detector drives a trigger to trigger a fire extinguishing medium storage device to release a fire extinguishing medium into the fire detection tube; c, giving an alarm and informing the smoke exhaust fan to work; d, when the fire detection tube is softened by high-temperature open fire and exploded by the high-pressure fire extinguishing medium, releasing the fire extinguishing medium to a fire source point of the battery cell; and e, when the fire is not extinguished or the battery core is re-combusted, triggering the glass ball of the spray head to be exploded at high temperature, and injecting fire-fighting water into the energy storage cabinet through the fire-fighting pipeline to extinguish the fire. The method is applied to the technical field of new energy and energy storage.

The invention relates to a method for constructing a hollow porous material through jujube peel fibers and carrageenan, an obtained product and application, and belongs to the technical field of food processing. The jujube peel fiber is combined with carrageenan, the fiber can serve as a framework support to form a stable hollow porous structure, the hollow porous structure provides larger surface area and pore volume, and the loading capacity of hydrophobic active ingredients can be increased. The inner surface of the prepared hollow porous structure material can adsorb hydrophobic active ingredients through non-covalent interaction such as physical adsorption and Van der Waals force. The structure can effectively protect the hydrophobic active component from being influenced by the external environment, so that the stability and bioavailability of the hydrophobic active component are improved. The structure not only can effectively load and protect hydrophobic components, but also can adjust the pore size by adjusting the ratio of the fibers to the carrageenan, and the smaller pore size can slow down the diffusion speed of the hydrophobic active components and prolong the release time, so that the hydrophobic active components can be released as required. The bioavailability of hydrophobic nutritional ingredients is improved.

The invention relates to a controlled-release linalool emulsion based on a ternary system as well as a preparation method and application of the controlled-release linalool emulsion. The linalool emulsion is an oil-in-water Pickering emulsion composed of a water phase and an oil phase, the water phase comprises a ternary system composed of soybean protein isolate, pectin and hydroxypropyl methyl cellulose, and the oil phase is linalool essential oil. The preparation method comprises the following steps: respectively preparing soybean protein isolate, pectin and hydroxypropyl methyl cellulose solutions, and mixing to obtain a ternary composite water phase; and mixing the ternary composite water phase with the oil phase, and carrying out high-pressure homogenization treatment and ultrasonic treatment under a low-temperature condition to obtain the controlled-release linalool emulsion based on the ternary system. Compared with the prior art, the linalool essential oil emulsion embedding method solves the problem that linalool is easy to volatilize, and can be used in the fields of fruit and vegetable fresh keeping, tea fragrance maintaining and the like.

The application discloses an intestinal-targeted controlled-release microalgae pharmaceutical composition, which comprises a hydrophobic drug, a micellar material and microalgae, wherein the hydrophobic drug is first loaded on the micellar material to form a drug-loaded micelle, the solubility of the hydrophobic drug is improved, and the drug-loaded micelle solution penetrates into the interior of the microalgae cells through a passive water absorption process of dried microalgae instead of being attached to the surface of the microalgae. The natural cell wall of the microalgae itself is solid and acid-resistant, which is used as a first physical barrier to prevent the release of the hydrophobic drug in a gastric acid environment, and the effective concentration and residence time of the hydrophobic drug in the intestinal action site are significantly improved, so that the treatment effect is better, and the intestinal disease and kidney disease drug can be prepared.

The invention relates to the technical field of blood products, in particular to an optimized plasma matrix and a preparation method thereof. The blood coagulation cascade reaction is efficiently activated by utilizing the thermal effect of near infrared rays, the formation of a three-dimensional fiber network structure in a plasma matrix is promoted, and the structure becomes more compact, so that the blood plasma has better tensile strength and longer degradation time, and a more ideal treatment effect is achieved; meanwhile, near-infrared irradiation can induce synthesis of collagen and elastin, wound healing is enhanced, light damage and skin aging are improved, and the application prospect is good.

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating scalds and a preparation method and application thereof. The traditional Chinese medicine composition for treating scalds is prepared from the following components: 10 to 15 parts of radix et rhizoma rhei, 10 to 15 parts of radix sanguisorbae, 10 to 20 parts of radix angelicae sinensis, 5 to 10 parts of rhizoma coptidis, 5 to 10 parts of cortex phellodendri, 10 to 20 parts of fructus gardeniae, 5 to 10 parts of rhizoma polygoni cuspidati, 5 to 10 parts of elm bark inner layer, 5 to 10 parts of herba portulacae, 5 to 10 parts of flos lonicerae, 2 to 5 parts of borneol, 0.1 to 0.5 part of preservative, 1 to 3 parts of humectant and 0.5 to 2 parts of thickening agent. By adopting the combination of multiple Chinese herbal medicines such as rheum officinale, raw sanguisorba officinalis, angelica sinensis, coptis chinensis, golden cypress, cape jasmine, polygonum cuspidatum, elm bark inner layer, purslane and honeysuckle, the synergistic effect of the traditional Chinese medicines is fully utilized, and the remarkable technical effects of clearing away heat and toxic materials, relieving swelling and pain and promoting wound healing are achieved. Compared with the technical scheme of single Chinese herbal medicine or simple mixing in the prior art, the medicine composition has the advantages that the comprehensiveness and the treatment effect of the medicine effect are remarkably improved, and the healing speed of scalds is increased.