2 results about "Donepezil Hydrochloride" patented technology

The utility model discloses a kind of donepezil hydrochloride tablets equivalent progressive addition mixing devices, it is related to pharmaceutical technical field, including fixed cylinder, the side of fixed cylinder is provided with the feeding mechanism for feeding, the top of fixed cylinder is fixedly connected with feeding pipe and is penetrated, the inside of fixed cylinder is provided with the stirring mechanism for mixing, the inner wall of fixed cylinder is slidably connected with mixing bucket one and mixing bucket two, the inner wall of fixed cylinder bottom end is fixedly connected with mixing bucket three, the bottom of mixing bucket one, mixing bucket two and mixing bucket three is all provided with the unloading mechanism for opening and closing, the side of mixing bucket one and mixing bucket two is all fixedly connected with fixed block, the bottom of fixed block is fixedly connected with spring and telescopic rod, solved if it is through the method of adding batch quantity to mix, not only time-consuming and laborious, while opening and closing feeding pipe every time, it will increase the risk of introducing foreign contamination source in the process of mixing drug, possibly affect the finished drug quality problem.

The present invention provides an oral dispersible film for donepezil hydrochloride. The film is a bilayer structure containing a drug layer containing 45-75% w / w donepezil hydrochloride and a backing layer without donepezil hydrochloride. The present oral film retains donepezil hydrochloride in a crystal form and minimizes impurity generation. The oral film contains a selected hydrophobic material to improve the drug stability and minimize the drug solubility.