22 results about "Formulation stability" patented technology

The invention relates to the technical field of cosmetics, in particular to polyurethane oleogel, a preparation method of the polyurethane oleogel and application of the polyurethane oleogel in an anhydrous cosmetic formula. The polyurethane oleogel is prepared from a water-dispersible polyurethane film-forming agent, volatile grease and an organic modified layered silicate thickening agent through high-speed homogenization, and solves the technical bottleneck that water-dispersible polyurethane is difficult to be directly applied to an oil wax-based anhydrous formula; and the synergistic improvement of the anti-transfer property, the smearing smoothness and the formula stability of the anhydrous cosmetic formula can be considered.

A cosmetic composition having a pearlescent effect, according to one aspect, provides a pearlescent effect without a pearlescent pigment so as to improve aesthetics, can be used in various formulations such as low-viscosity skin formulations, can exhibit structural colors, and has excellent long-term formulation stability.

The present invention relates to an oil-dispersed cosmetic composition having excellent suspension stability and, specifically, to an oil-dispersed cosmetic composition having excellent powder dispersibility, suspension stability, and formulation stability by optimally mixing a hydrogenated castor oil / sebacic acid copolymer as an oil thickener and silica dimethylsilylate as a dispersant.

A cosmetic composition for enhancing skin absorption of active ingredients and formulation stability is disclosed. The cosmetic composition contains three or more ingredients selected from the group consisting of bis-ethoxydiglycolcyclohexane 1,4-dicarboxylate, lysolecithin, citron seed oil, and glycereth-25 PCA isostearate. The cosmetic composition has effects of enhancing skin absorption of active ingredients and enhancing formulation stability.

According to the present invention, by using polysorbate and polyethylene glycol in combination, the solubility of a thiazolidinedione-based compound, particularly a thiazolidinedione-based compound having PPAR-γ agonistic activity, can be effectively improved. Therefore, the compound can be maintained in a homogeneous state in a composition without precipitation or crystal formation, and formulation stability suitable for local injection or local application can be ensured. In addition, the composition of the present invention can stably maintain the dissolved and dispersed state of the thiazolidinedione-based compound even at a low surfactant concentration, and thus can improve the reproducibility and application suitability of the formulation.

The invention discloses alkaline hydrolysis glue for double-color electroplating and a preparation method of the alkaline hydrolysis glue, the alkaline hydrolysis glue is uniform transparent liquid, and the alkaline hydrolysis glue comprises the following components in percentage by weight: 5.0-15.0 wt% of a film-forming agent, 2.0-8.0 wt% of an accelerant, 0.5-2.0 wt% of inorganic base, 0.1-1.0 wt% of a corrosion inhibitor, 80-90 wt% of a mixed solvent, 0.5-3.0 wt% of a cosolvent and 1-3 wt% of a dispersion stabilizer. The method has the advantages that the peptizing speed is increased, on-site preparation is not needed, the formula stability is high, the pungent smell is reduced, and the green production requirement is met.

This invention relates to the field of computer-aided process design technology, specifically to an intelligent optimization design method and system for greenhouse film formulations. The method includes the following steps: collecting signals of crystallinity, amorphous ratio, and crystalline inter-region spacing through film-making experiments and constructing a structure vector; completing crystallization discrimination based on transmittance targets and spacing thresholds; forming a formulation state sequence by combining raw material mass fractions and additive ratios; analyzing the crystallization evolution direction under multiple cooling and traction rate conditions; imposing constraints on parameter value ranges; and outputting the optimized greenhouse film formulation results. In this invention, through the joint characterization and discrimination of multi-dimensional signals of the crystal structure, formulation decisions rely on the microstructural state, combining the crystallization evolution direction and state transition relationship to form dynamic constraints on the raw material mass fraction and additive ratio, ensuring that the optimization results conform to processing conditions, reducing static parameter deviations, maintaining controllable performance and predictable trends under multiple operating conditions, and improving formulation stability and continuous adaptability.

An object of the present invention is to provide an eye care composition which can be produced with a reduced risk of failure during production by not using a bilberry extract raw material, has good formulation stability, and can be reduced in dosage.SOLUTION: The above object can be achieved by an eye care composition comprising a Haematococcus alga extract, a marigold extract, a propolis extract and vitamin A as active ingredients, and an eye care composition comprising astaxanthin, lutein, zeaxanthin, a propolis extract and vitamin A as active ingredients.SELECTED DRAWING: None

The present invention relates to a cosmetic composition having an excellent exfoliating effect and, specifically, to a cosmetic composition which comprises, as two or more types of thickeners, a Sargassum fluitans / Natans extract and polyacrylate crosspolymer -6, and thus can contain a high content of acid in a formulation, thereby having an excellent sebum-removing and exfoliating effect and excellent formulation stability.

An oil-in-water cosmetic composition having no clouding phenomenon. The oil-in-water cosmetic composition according to the present application, as an organic / natural cosmetic composition not containing a polyethylene glycol-based surfactant, a silicone oil, and / or a synthetic polymer, can provide a cosmetic composition having no clouding phenomenon and excellent formulation stability by simultaneously containing a fatty alcohol and a lecithin-based surfactant.

The present invention relates to a cosmetic composition containing glutathione as an active ingredient and, more specifically, to a cosmetic composition which, through a combination of glutathione, fullerene, and polyacrylate crosspolymer, exhibits excellent deodorizing efficacy against glutathione and excellent formulation stability and skin feel.

The present invention relates to an oil-in-water type liquid cosmetic composition having a high content of vitamin C and having improved formulation stability and feeling of use. The cosmetic composition according to the present invention comprises a high content of vitamin C, a derivative of vitamin C, an emulsifier, and a thickener, and is prepared by a method for achieving a stable formulation even under conditions of low viscosity and pH. Accordingly, it is possible to achieve a high content of vitamin C without precipitation, and simultaneously improve feeling of use and prevent oxidation in a cosmetic.

The present invention relates to a high-viscosity cosmetics composition having self-healing ability. The cosmetics composition of the present invention comprises a component having shear-thinning properties to maintain a cream phase while having high viscosity, thus being a good moisturizer and easy to spray, and having formulation stability.

The invention discloses a Rurugolil long-acting preparation composition as well as a preparation method and application thereof. The composition comprises an active medicine and at least one suspending aid. The Rurugolil long-acting preparation composition has an excellent slow-release effect, the administration interval can be prolonged to 7-90 days per time from 1 day per time, and the bioavailability, the compliance and the safety of a patient are remarkably improved. The pharmaceutical composition disclosed by the invention has the advantages of high preparation stability, simple prescription, controllable preparation process and capability of realizing industrial production amplification.

Disclosed in the present invention are a long-acting formulation composition of Relugolix, a preparation method therefor, and use thereof. The composition comprises an active drug and at least one suspending agent. The long-acting formulation composition of Relugolix of the present invention has an excellent sustained-release effect, can prolong the administration interval from 1 day / time to 7 days to 90 days / time, and significantly improves the bioavailability, compliance, and safety of patients. The pharmaceutical composition of the present invention has the advantages of high formulation stability, simple prescription, controllable preparation process, and scale-up capability for industrial production.

The invention discloses an eperisone hydrochloride tablet and a preparation method thereof, and belongs to the technical field of pharmaceutical preparations. The eperisone hydrochloride tablet contains eperisone hydrochloride, a filler, a disintegrating agent, a compound stabilizer, hydrophobic fumed silica and a lubricant, the compound stabilizer is composed of L-malic acid, citrulline and L-cysteine hydrochloride in a specific ratio, and the hydrophobic fumed silica and the compound stabilizer are in a specific weight ratio. The filling agent, the disintegrating agent and the lubricating agent are all selected from adaptive components. The eperisone hydrochloride tablet disclosed by the invention is prepared by adopting a direct powder tabletting process, and film coating can be carried out as required through pretreatment of raw materials and auxiliary materials, step-by-step mixing and tabletting. The defects that eperisone hydrochloride is high in hygroscopicity and sensitive to temperature, humidity and light are overcome from the two aspects of inhibiting degradation of main drugs and reducing moisture absorption, the stability of the preparation and the processing property of powder are improved, the process is simple, convenient and environment-friendly, low-temperature light-proof storage is not needed, and the eperisone hydrochloride powder is suitable for industrial mass production.

The present invention relates to an ultraviolet-blocking cosmetic composition, wherein the cosmetic composition contains zinc oxide stabilized in a formulation through a zinc oxide dispersion, and thus exhibits excellent formulation stability and adhesion, low white turbidity, and superior ultraviolet-blocking performance. Specifically, the present invention relates to an ultraviolet-blocking cosmetic composition, wherein the cosmetic composition exhibits low white turbidity and exerts high ultraviolet-blocking ability by optimizing a dispersion containing ultra-high-content zinc oxide particles through mixing with an emulsifier and a dispersant.

According to an embodiment of the present application, a cosmetic composition for UV protection is provided. The cosmetic composition comprises: an aqueous phase comprising a first UV-blocking agent; and an oil phase comprising a second UV-blocking agent and an oil gelling agent, wherein the oil phase is encapsulated and dispersed in the aqueous phase, and the oil gelling agent may comprise polyamide-3. According to embodiments of the present application, due to the use of an oil gelling agent, the oil phase can be encapsulated and dispersed in the aqueous phase. By using polyamide-3 as the oil gelling agent, the cosmetic composition can provide a transparent formulation and exhibit excellent formulation stability, feeling of use, and UV protection efficacy.

The present invention relates to an oil-in-water UV-blocking nanoemulsion cosmetic composition for makeup, comprising a nanoemulsion composition and powder. The cosmetic composition according to the present invention has improved moisturizing power, feeling of use, and skin absorption, and has excellent UV-blocking power and makeup effects. In addition, the present invention provides a method for preparing an oil-in-water UV-blocking nanoemulsion cosmetic composition for makeup having excellent formulation stability.

The present invention provides a siloxane-containing (meth)acrylate compound, a method for preparing the same, a photocurable composition, and a photocurable product. The (meth)acrylate compound has a structure selected from any one of Formula I, Formula II, and Formula III: wherein Ra is selected from any one of a C1-C6 alkyl group, a C6-C10 substituted or unsubstituted aryl group, Rb1 is a methyl group, Rc1 is H, any one of Rb2 and Rc2 is a methyl group, the other is H, any one of Rb3 and Rc3 is a methyl group, the other is H, and Rd is H or a methyl group. The (meth)acrylate functional group in the (meth)acrylate compound improves the surface peelability of the photocurable composition from a substrate, and the siloxane group improves the compatibility of the photocurable composition with a photocurable silicone resin, thereby improving the formulation stability of the photocurable composition and effectively improving the adhesion and surface peelability of the photocurable composition from a substrate. 10 20 The present invention provides a siloxane-containing (meth)acrylate compound, a method for preparing thesame, a photocurable composition, and a photocurable product. The (meth)acrylatecompound has a structure selected from any one of Formula I, Formula II, and Formula III: wherein Rais selected from any one of a C1-C6 alkyl group, a C6-C10substituted or unsubstituted aryl group, Rb1is a methyl group, Rcis H, any one of Rb2and Rcis a methyl group, the other is H, any one of Rb3and Rcis a methyl group, the other is H, and Rdis H or a methyl group. The (meth)acrylate functional group in the (meth)aery late compound improves the surface peelability of the photocurable composition from a substrate, and the siloxanegroup improves the compatibility of the photocurable composition with a photocurable silicone resin, thereby improving the formulationstability of the photocurable composition and effectively improving the adhesion and surface peelability of the photocurablecomposition from a substrate.​

The invention discloses a composite sun-screening agent and a preparation method and application thereof, the composite sun-screening agent comprises a core layer and a shell layer, the material of the core layer comprises inorganic sun-screening particles, and the material of the shell layer comprises silicon dioxide and a natto extract; during preparation, the surface of the core shell is coated with a silicon dioxide precursor, and then the surface is coated with the natto extract; the composite sun-screening agent disclosed by the invention realizes the integration of multiple functions of sun screening, oxidation resistance, skin care and repair and the like, has obvious advantages in the aspects of sun-screening stability, skin protection capability, use skin feeling, formula stability, safety, environmental friendliness and the like when being used in cosmetics, can simultaneously realize an oxidation resistance effect and an ultraviolet protection effect, and has a good application prospect. And more comprehensive skin protection is provided. In addition, cosmetics adopting the composite sun-screening agent disclosed by the invention also have excellent skin feelings such as refreshing degree, fitting property, high absorption speed and the like.