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Galantamine is used to treat mild to moderate confusion (dementia) related to Alzheimer's disease.
A bipyridine compound, a preparation method thereof and application thereof in preparing AChE inhibitors
The application belongs to the technical field of biological medicine, and relates to a bipyridine compound, a preparation method thereof and application of the bipyridine compound in preparation of an AChE inhibitor. A chemical structural formula of the bipyridine compound is provided. The bipyridine compound provided by the application has AChE inhibitory activity, and the AChE inhibitory activity of the bipyridine compound is significantly higher than that of an existing clinical drug (such as galantamine), thereby providing a drug with better effect for treatment of Alzheimer's disease.
Owner:SHANDONG UNIV +1