46 results about "Metrifonate" patented technology

The invention relates to a method for detecting ten types of organophosphorus pesticides by using magnetic separation-gas chromatography. The method is used for quickly detecting ten types of organophosphorus pesticides (dipterex, methamidophos, acephate, omethoate, moncrotophos, dimethoate, phosphamidon, parathion-methyl, malathion and chlorpyrifos) based on combination of solid-phase extraction, magnetic separation and the gas chromatography. The method comprises the following steps: preparing a magnetic solid-phase extraction agent, establishing a combination system of the magnetic separation and the gas chromatography, and detecting the organophosphorus pesticides in objects to be detected. A method capable of quickly separating and detecting ten types of organophosphorus pesticides at high sensitivity simultaneously is established by taking prepared magnetic chitosan microspheres with high absorption performance on the ten types of organophosphorus pesticides such as dipterex and the like as adsorption functional materials and using combination of the solid-phase extraction, magnetic separation and the gas chromatography. The method is simple in experimental operation, high in detection sensitivity, low in cost and applicable to detection of residues of ten types of organophosphorus pesticides such as trace dipterex and the like in all products.

The invention relates to a pharmaceutical composition based on an active ingredient that is enclosed in liposomes for topical, transdermal application. The interior of said liposomes comprises an acidic, aqueous medium containing at least one cholinesterase inhibitor, preferably from the group containing donepezil, rivastigmine, galantamine, physostigmine, heptylphysostigmine, phenserine, tolserine, cymserine, thiatolserine, thiacymserine, neostigmine, huperzine, tacrine, metrifonate and dichlorvos, or an enantiomer or derivative of at least one of said compounds. In addition, the invention relates to a method for producing said composition, optionally in a sterile form and also to the use of the liposomes charged with the active ingredient in various galenic formulations for topical, transdermal application with a depot effect in the epidermis, for the prophylaxis and/or treatment of cutaneous neuropathic pain or the loss of cutaneous sensory function as a result of neuropathy.

The invention relates to the technical field of medicine for prevention and control of diseases and insect pests, and especially relates to a citrus tetradacus citri prevention and control liquid anda preparation method thereof; brown sugar, Baijiu, white vinegar, trichlorfon and water are controlled according to a certain proportion, the trapping effect of the insect prevention liquid is significantly enhanced, the effect of prevention and control of citrus tetradacus citri is improved, and the citrus planting cost is reduced.

The invention relates to a Rhodobacter sphaeroides and an application thereof. A novel strain Rhodobacter sphaeroides XR12 screened by the inventors has high tolerance to trichlorfon in a water environment or an aquaculture environment, can reduce the toxicity of trichlorfon in the water environment or the aquaculture environment, and can be applied to the aquaculture field or the water environment treatment field.

An antibactieral composite fertilizer contains N and/or P and/or K fertilizer (10-90 wt.%), naphthalene (0.5-3), chlorothalonil (0.01-1), trichlorfon (0.05-1.2), phoxim (0.01-1.1) and auxiliary. Its advantages are rich nutrients, high insecticiding effect and increasing yield of crops.

The pesticide for crop has effective components including trichlorfon and high effect cypermethrin or cypermethrin in the weight ratio of 1-130, preferably 25-45 and supplementary components including surfactant, agglomeration resisting agent and filler. It is diluted with water before sprayed to rice field to prevent and kill striped rice borer and yellow rice borer and other borer with the use amount being 50-150 g each mou.

The invention discloses a plastic greenhouse soilless flowing water culture technical scheme for eels and belongs to the technical field of aquaculture. Rearing ponds are built by adopting bricks and cement, the area of each pond is 10-20 square meters, each pond is 40cm deep and 1-2m wide, and a pond bank is 20-40cm wide; a plurality of rearing ponds are arranged in parallel to form one unit, the area of each unit is best not more than 500 square meters; and 0.1g of 90% crystal trichlorfon is used for per kilogram of eels and is mixed into feed for feeding for six days continuously, so that the technical scheme is completely implemented. The technical scheme disclosed by the invention is beneficial to improving cultivation quality of the eels, health is important due to edible eels, disinfection treatment in each aspect and control methods of plant diseases and insect pests are beneficial to improving health condition of the eels, self physique is perfect, and great taste when the eels are eaten can be enhanced, so that the technical scheme disclosed by the invention has better economic value and is convenient for popularization.

The invention belongs to the technical field of pesticides and particularly relates to a special mite-killing chemical for bees and a use method. According to the technical scheme, the special mite-killing chemical for the bees comprises components in percentage by weight as follows: 15%-25% of sublimed sulfur, 10%-20% of carbolic acid, 5%-15% of trichlorfon, 10%-20% of boric acid, 15%-25% of boric acid, 5%-15% of naphthalene and the balance of coal ash, and the components are mixed to prepare powder. The chemical contains simple components and does not contain chemical drugs that are harmful to a human body, the components are easy to volatilize and decompose and are pollution-free for bee products, and the chemical is volatilized quickly, is safe and harmless for the bees and has high mite-killing efficiency.

The invention discloses a preparation method and applications of a cDNA (complementary Deoxyribonucleic Acid) chip for detecting drug resistance level of bactrocera dorsalis resistant to trichlorphon and beta-cypermethrin. Upregulated drug resistance specificity expression gene segments of different resistant strains of bactrocera dorsalis can be obtained respectively by utilizing a forward suppression subtractive hybridization method, the related drug-resistant specificity expression genes are subjected to PCR (Polymerase Chain Reaction) amplification, 118 related resistance specificity gene segments of bactrocera dorsalis resistant to trichlorphon and 103 related resistance specificity gene segments of bactrocera dorsalis resistant to beta-cypermethrin can be obtained through purifying and recovering. The cDNA chip for detecting the resistance of bactrocera dorsalis resistant to trichlorphon and beta-cypermethrin can be constructed by taking the specific resistant target gene segments as DNA probes. The cDNA chip can simply and effectively realize the real-time detection on the drug resistance level of bactrocera dorsalis.

The invention relates to an ultra low-volume liquid containing metaflumizone and an organophosphorus pesticide. The ultra low-volume liquid comprises a chemical component compounded of metaflumizone and an active ingredient II, and the balance at least one surfactant and at least one solvent, wherein the active ingredient II is any one of fenitrothion, trichlorfon, methyl parathion, isazofos, pyridafenthion, quinalphos, triazophos, fosthiazate, diazinon, phoxim, fenitrothion, pirimiphos-methyl, fenthion, cyanophos, profenofos, chlorpyrifos, chlorpyrifos-methyl, prothiofos, sulprofos, dimethoate, malathion, methidathion and isocarbophos. The ultra low-volume liquid is convenient for processing, has a long duration of efficacy and high efficacy, does not cause pesticide resistance of targets easily, produces low pollution on the environment, saves pesticides and water, improves a pesticide utilization rate, and realizes control of insect pests damaging paddy, wheat, corn, vegetables, tobacco, tea trees, fruit trees and sugarcane through ultra low-volume spraying, low-volume spraying or ultra low-volume electrostatic spraying.

The present invention relates to synergistic precursor medicine compound for treating Alzheimer disease or its salt and their preparation process, and medicine composition containing the compound or its salt and their application in treating Alzheimer disease. Specially, the compound, which is (1-dimethyl phosphoryl-2, 2, 2-trichloro)-ethyl-1-alcohol nicotinate, is formed with nicotinic acid and metrifonate and through ester bond coupling. The compound or its salt of the present invention has excellent effect on treating Alzheimer disease.

The invention relates to continuous granulation process equipment for trichlorfon. Synthesized trichlorfon materials are put into a heat preservation kettle to be gradually cooled, it is guaranteed that the materials are in a liquid state, and then the materials are conveyed into a pre-crystallizer through a feeding pump to be slightly cooled; and trichlorfon slurry flowing out of the pre-crystallizer is fed into a granulator. The materials are dropped on an annular steel belt through a distributing device, a cooling liquid spraying device can be arranged between the distributing device and the annular steel belt, trichlorfon liquid drops are dropped in cooling liquid to form hard spherical white particles, and then the hard spherical white particles flow out, and finally the hard spherical white particles are dried and cooled. According to the equipment of the invention, no three wastes are discharged basically, so that occupational health injury is reduced; heat generated by synthesis of the trichlorfon is recycled through heat exchange, so that environmental protection and energy conservation are realized; and the particle size of the finished product is more uniform and rounded, and the appearance and the production efficiency of the product are improved.

The invention discloses an agent used for preventing and treating hawkmoth pests on impatiens balsamina L. The agent comprises the following components in parts by weight: 20-24 parts of 20% fenvalerate-fenitrothion emulsifiable concentrate, 10-16 parts of 70% trichlorphon, 8-12 parts of 50% fenitrothion emulsifiable concentrate, 4-7 parts of pepper powder, 3-6 parts of polyoxyethylene alkyl aryl ether, 3-5 parts of isopropyl phosphate, 5-8 parts of Turkey red oil, 3-7 parts of dimethylformamide, 2-3 parts of astragalus polysaccharide, 5-10 parts of vinegar, 3-6 parts of indigo naturalis, 3-6 parts of sodium fluosilicate and 40-50 parts of water. A use method comprises the following steps: proportionally allocating and mixing the components and stirring the components uniformly to obtain the agent for prevention and treatment; then spraying the agent around affected plants after diluting the agent for prevention and treatment. The agent has good prevention effects, is convenient to use, reduces the pesticide consumption, reduces environmental pollution and is beneficial to ecological balance.

The invention discloses a preparation method of a trichlorfon sol-gel imprinted sensor, which sequentially comprises the following steps: pretreating a glassy carbon electrode, reducing a graphene oxide modified electrode, preparing a sol-gel pre-polymerization solution, preparing a sol-gel imprinted membrane by electro-polymerization, eluting template molecules and the like. According to the invention, the trichlorfon is used as a template molecule, methyltrimethoxysilane is used as a functional monomer and tetramethoxysilane is used as a cross-linking agent; the imprinted polymer membrane prepared by using a sol-gel method by is high in rigidity and relatively large in specific surface area, so that template molecules and the functional monomer can form a stable host-guest compound; the template molecules can keep a good rigid structure in a polymer net structure and form a cavity with a memory effect, and the prepared sensor is high in selectivity, good in stability, high in sensitivity, low in cost and fast in response. The method is suitable for rapidly detecting the trichlorfon residues in the plant-derived food.

The invention, which relates to the technical field of food detection, discloses a detection method for measuring the trichlorfon in meat food by liquid chromatography-tandem mass spectrometry. The method comprises: 2g to 10g of pork samples are weighed by using an electronic scale, the pork samples are placed in a beaker, 30mL to 100mL of ethyl acetate is added into the beaker, the samples and the ethyl acetate are mixed uniformly by using a homogenizer, and then ultrasonic processing is carried out for 10 min to 20 min in normal temperature water bath; the ethyl acetate extract of the pork samples is transferred to a separating funnel, centrifugal processing is carried out for 5 to 10min in a centrifuge tube at a centrifugal speed that is controlled to be 8000-10000r/min, so that an extract is obtained. According to the invention, the trichlorfon in the port is detected by using the liquid chromatography tandem mass spectrometry and the separation ability of chromatography is combined with the qualitative function of mass spectrometry, thereby realizing the accurate quantitative and qualitative analysis of trichlorfon in pork food. In detection of the trichlorfon residues in porkfood, the interference can be effectively eliminated and the stability of a to-be-tested object can be ensured. Moreover, the detection and analysis method has high sensitivity and high accuracy.

The invention provides a preparation method and production equipment for continuous production of trichlorfon, and effectively solves the problems of low production efficiency, poor production stability and safety, poor product quality and low yield of the existing production method. The continuous production method of trichlorfon comprises the following two stages of synthesis reactions for continuously preparing trichlorfon: (1) adding trichlorfon into a I-stage synthesis kettle as a synthesis kettle reaction mother liquor, then simultaneously dropwise adding trichloroacetaldehyde and dimethyl phosphite for reaction, and controlling the reaction temperature to be 75-85 DEG C; (2) enabling the reaction materials to enter a second-stage synthesis kettle from the first-stage synthesis kettle to continuously react, and controlling the reaction temperature to be 75 DEG C; and the product trichlorfon is obtained after the reaction in the I-stage synthesis kettle and the II-stage synthesiskettle.

The invention relates to the field of cotton pest prevention and control and application thereof, and provides an insecticidal composition containing pyridine quinazoline and diazinon, wherein the insecticidal composition comprises an effective component A and an effective component B, the effective component A is pyridine quinazoline, the effective component B is one of diazinon, phoxim, chlorpyrifos, trichlorphon and fosthiazate, and the part ratio of the effective component A to the effective component B is (0.1-50):(50-1). Pyridine quinazoline and diazinon are compounded, a remarkable synergistic interaction effect is achieved within a certain proportion range, the deinsectization effect of the composition is obviously improved compared with that of each single agent, the deinsectization efficiency and the pesticide application stability are effectively guaranteed, and the pesticide effect time is long; in the actual use process, the excellent prevention and control effect on agricultural pests is achieved; and the insecticidal composition has the advantages of excellent long-term prevention and control effect, long-term use, reduction of the use amount of pesticides, effective mitigation of environmental pollution, and high social use value and application prospects, and can effectively prevent the pests from generating obvious pesticide resistance at the same time.