487results about How to "Fast disintegration" patented technology

The invention relates to a fertilizer water dispersible granule and a method for preparing the same. The fertilizer water dispersible granule comprises one or more of plant nutrient substances and at least one surfactant which are processed to prepare the regular or irregular granular water dispersible granule. The fertilizer water dispersible granule consists of the following raw materials in portion by weight: 5 to 95 portions of the plant nutrient substance, 1 to 40 portions of the surfactant and 0 to 94 portions of an assistant. The invention has a preferential proposal: the plant nutrient substance comprises monopotassium phosphate, boric acid or borax, humic acid and salt thereof. The fertilizer water dispersible granule also comprises one or more of growth regulators. In addition, the fertilizer water dispersible granule can also comprise a disintegrating agent, an adhesive, a filler, a colorant and other assistants. The preparation method comprises: the metering, pulverization, even mixing, pelletization and drying of formula materials to obtain the fertilizer water dispersible granule. The fertilizer water dispersible granule has rapid disintegrating and dissolving (dispersing) speed in water, is fully dissolved, does not block a nozzle and a drop irrigation pipeline, is uneasy to absorb moisture, has high content of effective compositions, low packaging, storage, transportation, metering and use cost and high utilization rate of the effective compositions, reduces waste and environmental pollution, is widely applied to economic crop, gardening, lawn and urban greening and has extremely wide market application prospect.

The invention relates to an effervescent composition of a water-soluble fertilizer and a preparation method thereof. The effervescent composition contains one or a plurality of plant nutrient substances and one or a plurality of compounds which are contacted with water to generate gas. The effervescent composition comprises an optimized proposal that the plant nutrient substance is monopotassium phosphate. The effervescent composition can be also added with acid, a plant growth conditioner, a surfactant, a filler, a disintegrating agent, an adhesive, dye, a lube and the like. The preparation method comprises the following steps: ingredients are weighed, mixed, pulverized, pelletized and dried to obtain the effervescence composition. The effervescent composition can be manufactured through a routine production process, has rapid disintegrating and dissolving (diffusing) speed in the water, does not block a spray head or drip a pipeline, is uneasy to absorb dampness, has high content of effective compositions, low packaging, storage, metering and using cost and high utilization rate of the effective compositions, reduces waste and pollution to environment, is widely applied to economic crops, gardening, lawns and urban landscaping and has wide market application prospect.

The invention discloses a flucarbazone-Na compounded herbicide which comprises an active component I (flucarbazone-Na), an active component II and auxiliary components, wherein the active component II is one or a combination of several of mesosulfuron methyl, isoproturon, chlortoluron, pyroxsulam, Clodinafop-propargyl, carfentrazone-ethyl, tribenuron-methyl, fluroxypyr, methoxone, 2,4-D-butyl ester, dicamba, bromoxynil, thifensulfuron methyl, amidosulfuron, bensulfuron-methyl, flumetsulam, fluoroglycofen-ethyl and florasulam; the auxiliary components comprise an auxiliary agent and also comprise one of a filler and a solvent; the auxiliary agent is one or a combination of two of an emulsifying agent, a dispersant, a wetting agent, a disintegrant, an agglomerant, an antifreezing agent and a thickening agent; the mass sum of the active component I (flucarbazone-Na) and the active component II is 1%-85% of the total mass of the flucarbazone-Na compounded herbicide; and the mass ratio of the active component I to the active component II is (1:20)-(20:1). The flucarbazone-Na compounded herbicide disclosed by the invention is a novel herbicide for preventing and removing weeds in a wheatland.

The invention discloses a mesosulfuron-methyl compound herbicide which consists of mesosulfuron-methyl as active ingredient I, active ingredient II and auxiliary ingredients; the active ingredient II is the combination of one or more of flucarbazone-Na, isoproturon, chlortoluron, pyroxsulam, 2-methyl-4-chlorophenoxy acetic acid, 2,4-D butyl ester, dicamba, bromoxynil, amidosulfuron, bensulfuron-methyl, flumetsulam, fluoroglycofen-ethyl and florasulam; the auxiliary ingredients consists of adjuvant and one of filler and solvent, and the adjuvant is the combination of one or more of emulsifying agent, dispersing agent, wetting agent, disintegrant, binding agent, antifreezing agent and thickening agent; the sum of the weight of the mesosulfuron-methyl as the active ingredient I and the weight of the active ingredient II is 1 to 85 percent of the total weight of the mesosulfuron-methyl compound herbicide; and the weight ratio of the active ingredient I to the active ingredient II is 1:20 to 20:1. The mesosulfuron-methyl mixed herbicide is novel herbicide for wheatlands.

The effervescent health beverage table is featured by that it contains functional oligosaccharide, such as oligo-xylose, oligo-fructose, oligo-galactose, oligo-isomaltose, etc., with bifidobacterium proleferating function and may contain medicine, vitamins, minerals, soluble chitin and other functional factors. The tablet is produced through sieving, mixing, drying at 55-65 deg.c and tableting. The effervescent health beverage tablet, when being thrown into water, will be dissolved instantly into homogeneous beverage, health liquid, medicated tea, etc. while producing bubbles and turning up and down.

The invention relates to a pomegranate peel polyphenol antibiosis and antiphlogosis effervescent tablet as well as a preparation method and application thereof. The effervescent tablet is mainly prepared by raw material of pomegranate peel polyphenol, and auxiliary materials of sodium hydrogen carbonate, citric acid or tartaric acid, lactose, polyvinylpyrrolidone, magnesium stearate and superfine silica powder, has the functions of clearing heat, eliminating dampness, killing bugs and stopping itching, has strong suppression effect to women vagina pathogenic bacteria, features high safety, good stability, no obvious toxic or side effect, or drug tolerance, and provides convenience in using, carrying and storing for patients, is used for curing such diseases as vaginitis, vulvitis and the like caused by various trichomonad, epiphyte and bacteria, and can be used as preventability medicine for long-term use.

The invention relates to a Niuhuangshangqing soft capsule and a preparation method thereof, as well as a quality control method of capsule contents. The Niuhuangshangqing soft capsule comprises contents and capsule shell. The contents include an extent of Chinese medicinal materials in Niuhuangshangqing prescription and a dispersion medium with a weight ratio of 1:(1-2), wherein, the dispersion medium is vegetable oil. The soft capsule is prepared by extracting effective components from Chinese medicinal materials in Niuhuangshangqing prescription in accordance with the properties of the effective components by using different modern extraction techniques and making into soft capsule. The soft capsule has embedding and masking effects, and can prevent volatilization loss of oil components and oxygenation or photodecomposition of effective components. The soft capsule also has the advantages of rapid disintegration, uniform dispersion, high bioavailability, good stability of effective components, low liability of moisture absorption, good air tightness, direct intestinal absorption after disintegration, masking of unpleasant odors of effective components, convenience for administration and carrying, and so on.

An effervescent tablet for improving the immunizing effect of vaccine by dissolving it in drinking water contains water-soluble non-volatile weak solid acid and hydrogen carbonate salt, water-soluble solid auxiliary and color indicator and leavy metal chelating agent.

The invention discloses a plant growth regulator and application thereof. The plant growth regulator has active components of prohexadione calcium and uniconazole. Experiment show that prohexadione calcium and uniconazole have obvious synergism, so as to realize an ideal anti-lodging effect, eliminate side-effects caused by individual existence, and substantially reduce a usage amount of the active components, environmental pollution, and agricultural cost.

The invention discloses a preparation method of effervescent tablets. Polyethylene glycol is heated and melted and then is diluted with ethanol, a polyethylene glycol-ethanol solution is formed and then coats an acid source and an alkaline source, and accordingly, acid-source granules coated with polyethylene glycol film layers and alkaline-source granules coated with polyethylene glycol film layers are formed; the acid-source granules and the alkaline-source granules are sufficiently mixed and stirred, a mixture is formed, an ethanol solution of polyvinylpyrrolidone K30 is added to the mixture for secondary coating, a product is crushed after being dried, and effervescent granules coated with double organic film layers are obtained after uniform mixing; main medicine ingredients of a medicine and other acceptable excipients used for preparation of the effervescent tablets are added to the effervescent granules, and the effervescent tablet preparations are obtained through tableting after sufficient mixing. The prepared effervescent tablets are not prone to moisture absorption and deterioration and have good flowability; the forming rate is high, and sticking is avoided; the disintegration is fast. According to the method, adopted raw materials are cheap and easy to obtain, the method is simple, pollution-free and harmless to a human body, has low requirements for equipment and has good application prospect, and industrial production is easily realized.

The invention discloses propanil water dispersible granules. The propanil water dispersible granules comprise the following ingredients in percentage by weight: 10-80% of propanil, 1-10% of a dispersing agent, 1-12% of a wetting agent, 1-25% of a disintegrating agent, 1-10% of an adhesive, 1-5% of a chelating agent and the balance being a carrier. The propanil water dispersible granules disclosed by the invention are simple in preparation technology, low in cost, safe, environmentally-friendly, free of dust pollution, difficult to cause pesticide hazard, convenient to use and suitable for large-scale popularization and application, adapts to high-concentration wastewater and has the good shaping property and excellent prevention effect on grass families in paddy fields and dicotyledonous weeds such as barnyard grass, monochoria vaginalis, water fennels, crab grasses and green bristlegrass.

The invention discloses a method for preparing a fresh ginsengfreeze-dried oral instant preparation, and belongs to the technical field of medicinalhealthcare products. The method for preparing the fresh ginsengfreeze-dried oral instant preparation comprises the following steps: adding pure water into fresh ginseng, grinding by using a grinding machine, filtering, squeezing the residues, combining the filtrate, feeding the filtrate into a high-pressure equipment kettle, boosting the pressure to be 500-600MPa, keeping the pressure for 10-15 minutes so as to obtain a ginseng extract, filling the ginseng extract into a freeze-drying bottle, putting into a freeze-drying machine for rapid freezing, vacuuming, and heating a plate layer until analysis drying is completed, thereby preparing the fresh ginsengfreeze-dried oral instant preparation. The fresh ginsengfreeze-dried oral instant preparation prepared by using the method has the characteristics of being highin disintegration speed, high in bioavailability, high in dissolution rate, small in nutrient component consumption, easy to absorb by human bodies, high in absorption speed and relatively small in volatile oil component loss.

The invention relates to orally disintegrating tablets containing lurasidone and a preparation method thereof. The orally disintegrating tablets comprise lurasidone hydrochloride, filler, disintegrant, flavoring agent and lubricant, wherein the grain diameter D90 of the lurasidone hydrochloride is less than or equal to 75 mu m. The lurasidone orally disintegrating tablets have good dissolution in vitro and excellent taste; the orally disintegrating tables are simple in preparation process, and industrial production can be realized by adopting conventional granulation and tabletting equipment.

The invention discloses mesophilous bacterial chlorin water dispersion granule agent in disinfectant, and belongs to the disinfectant technology in the plant protection field. The invention comprises the components that the raw material medicine mesophilous bacterial chlorin occupies 100 to 600 shares, auxiliary agent occupies 180 to 360 shares, carrier packing material occupies 250 to 600 shares, and binding agent occupies 10 to 150 shares. The ingredients are mixed proportionally, after being evenly mixed, the mixture is crushed to obtain the target powder, the target powder and the binding agent are evenly mixed, and the mesophilous bacterial chlorin water dispersion granule can be obtained through granulation, drying and screening. The invention overcomes the disadvantage of the wettable powder of the mesophilous bacterial chlorin, both the us-cost of the farmer and the environment pollution are reduced. The invention has the advantages that the content is high, the disintegration is quick, the dispersivity is good, the invention is advantageous for storage and transportation and the stability is good, the activeness is high, the efficiency is good, and the invention is secure.

The present invention provides a soft capsule and its preparation method. The composition of said soft capsule includes (by wt%) 8-45% of prolanpolysaccharide 0.01-2.5% of plant gelling agent, 1-15% of plasticizer, 33-89% of oil solution, 0.1-1% of paraffin wax, 0.01-1% of coloring matter and 0.9%-12% of water. Said invention also provides the concrete steps of its preparation method.

The invention relates to an effervescence tablet for treating common cold, wherein the raw materials include atractylodes rhizome, Bupleurum root, notopterygium root, ledebouriella root, dahurian angelica root, Ligusticum wallichii, patchouli, peucedanum root, capsule of weeping forsythia, dried orange peel, haw, immature bitter orange, malt, licorice root, root of ballon flower, medicated leaven, purple perilla, magnolia bark and black tea.

A fast dissolving tablet. The fast dissolving tablet comprises a pharmaceutically active ingredient, a starch, a hydrophilic polymer, a surfactant, and excipients. A method of preparing the fast dissolving tablet is also disclosed.

The invention provides an amoxillin-potassium clavulanatein 4:1 dispersible tablet. The dispersible tablet adopts lactose, crystallite fibrin and crystal mannitol as thinner, and adopts crosslinked polyvinyl pyrrolidone (XL type) as disintegrant and also adopts micro-powder silica gel and magnesium stearate as lubricant. The dispersible tablet of the invention adopts the lactose and mannitol with better fluidity, which is good for directly pressing the powder into tablet. The invention also provides a technique of the dispersible tablet: subsidiary substances are dried for 12 to 16 hours at the temperature of 80 to 100 DEG C; the two-time tablet pressing technique is adopted and the crystallite fibrin is added both internally and externally. The environment-humidity is less than 28 percent, and the environment-temperature is below 30 DEG C in the whole preparation process. The method of the invention thoroughly dries the subsidiary substances and the process environment-humidity is controlled, so as to guarantee the stability of the product; the mixing between the subsidiary substances and the medicines, the internal and external adding method is adopted, so as to enhance the disintegrating speed of the dispersible tablet; by adopting the two-time tablet-pressing method, the dispersing equality and hardness of the dispersible tablet can be improved.

The invention relates to a boron fertilizer effervescence granule and method of producing the same, pertaining to a novel boron fertilizer. The boron fertilizer effervescence granule includes one or more boron fertilizer and one or more compounds contacted with water to generate gas, wherein, the weight part scope of the boron fertilizer is from 61 to 95. The preferred scheme of the invention is that the boron fertilizer includes one of boric acid, boron oxide, ammonium pentaborate, sodium tetraborate, calcium metaborate, sodium metaborate, tetrahydate octa sodium borate, magnesium diboride, sodium perborate, zinc borate, manganese borate, sodium perborate, potassium metaborate, boron magnesium fertilizer, boron and magnesium phosphate, and boron mud, or a mixture of two or more of the above. The preparation method of the invention includes: weighing the formulation material, mixing, grinding, granulating, and drying to obtain. The inventive boron fertilizer effervescence granule has a fast disintegrating velocity in the water; completely dissolving(dispersing); non-clogging of nozzle and drip irrigation pipeline; no need of heating when in use; no absorption of moisture; low packaging, storage and transportation, measurement and use cost; wide application in food crops, cash crops, horticulture, lawns and urban greening; and very broad market prospect.

The invention discloses a medicament for kidney tonifying, which is prepared from gen-seng, broomrape, hairy deerhorn, cornus officinalis, eucommia bark, cynomorium songaricum, epimeddium, morinda root, wolferry fruit, fleece-flower root, poria cocos and licorice root. The medicament can be prepared into any of the conventional oral dosage forms.

The invention relates to a compound liquorice tablet and a preparation process thereof. The compound liquorice tablet comprises the following raw materials: liquorice root extracts, opium powder, camphor, star anise oil, sodium benzoate, an adsorbent and a corrective. The preparation process comprises the following steps: adding the adsorbent in the raw material composition, and hiding special foul smell of the camphor and the star anise oil by adopting an adsorption method to eliminate the foul smell; adding the corrective in the raw material composition to enable the compound liquorice tablet to have satisfactory mouthfeel. Therefore, the compound liquorice tablet prepared by the invention is suitable for being taken orally, excellent in mouthfeel, good in clinical effects, and high in bioavailability. Meanwhile, through the improvement on the process, especially, a manner of performing direct tabletting on powder is adopted, so that the compound liquorice tablet is remarkably improved in process level, stable in quality and stable in effect; the production cost of the product is further reduced, and the tablet can serve patients better.

The invention relates to the field of pharmacy, and discloses a benzoic acid alogliptin composition troche and a preparation method thereof. The effective components of the benzoic acid alogliptin composition troche comprise benzoic acid alogliptin, mannitol, microcrystalline cellulose, croscarmellose sodium, magnesium stearate and 5% hydroxy propyl cellulose aqueous liquor. The synthetic materials are easy to obtain and low in cost. The troche is quick in disintegration speed, high in dissolution rate, good in stability, accurate in dosage and convenient to take and carry. The benzoic acid alogliptin composition troche is simple in step, short in production period, low in production cost and suitable for industrialized application, and the technical process is easy to control,.

The invention discloses a compound alpha-keto acid tablet, which comprises five amino acids and five keto acid calcium salts. By improving auxiliary materials, the tablet improves the disintegration time and the stability and overcomes unpleasant odor of the existing tablet. Simultaneously, the invention further discloses a preparation method of the tablet.

The invention discloses a medicine compound containing candesartan cilexetil, and a preparation method thereof; and the medicine compound improves the stability of the base medicine and improves the dissolution rate of the medicine by preparing solid dispersion. The medicine compound is used for curing primary hypertension.

The invention discloses an oral rehydration salt effervescent tablet which mainly contains sodium chloride, postassium chloride, anhydrous dextrose, citric acid, sodium bicarbonate and / or sodium carbonate and water-soluble lubricant. The invention also discloses the application of the oral rehydration salt effervescent tablet. The oral rehydration salt effervescent tablet is convenient to carry and use. The dosages of an acid source and an alkali source in the oral rehydration salt effervescent tablet can reflect the dosage of sodium citrate needed by the prescription for producing oral rehydration salt (ORSII), thereby reducing the addition of the raw material sodium citrate and lowering the production cost effectively.

The invention belongs to the technical field of drug preparation and specifically relates to a sitagliptin phosphate tablet and a preparation method thereof. The sitagliptin phosphate tablet comprises the following raw materials in parts by weight: 30 parts of sitagliptin phosphate, 55-70 parts of filler, 0-5 parts of adhesive, 1.5-3.0 parts of disintegrating agent and 1.5-5.0 parts of lubricating agent; the filler is selected from one or more of microcrystalline cellulose, sugar and inorganic salt; the adhesive is selected from one or more of hydroxypropyl methylcellulose, hydroxypropylcellulose, povidone K30 and starch; the disintegrating agent is selected from one or more of crosslinking sodium carboxymethylcellulose, sodium carboxymethyl starch and polyvinylpolypyrrolidone. Compared with the prior art, the sitagliptin phosphate tablet provided by the invention has the technical effects of easily acquired compound raw materials, high disintegration speed, high dissolution rate, high stability, simple steps of preparation method, easily controlled technological process, short production period, low production cost and suitability for industrialized application.

The invention belongs to the field of agricultural fertilizers, and relates to a disintegratable round-granule sulfur magnesium fertilizer. Powdery brucite and sulfur powder are used as main raw materials, and a magnesium sulfate heptahydrate solution is used as a binding agent. The disintegratable round-granule sulfur magnesium fertilizer is prepared by granulating the following components in parts by mass: mixture of 90-95 parts of powdery brucite and 5-10 parts of sulfur as the dry material, and magnesium sulfate heptahydrate solution as the binding agent. After drying the round granules, the water content is less than or equal to 3%, the strength is greater than or equal to 2Kg / cm<2>, and the disintegration rate is greater than or equal to 95%. The magnesium sulfate heptahydrate solution is used as the binding agent to enhance the granulation rate; the 60-120 mesh powdery brucite and sulfur powder are mixed as the dry material; and granulation, screening, drying, cooling and packaging are carried out to prepare the spherical granules with the granular size of 2-4mm. The invention has the advantages of low cost, high magnesium content and high disintegration speed. The product is spherical granules, has the advantages of favorable disintegratability, uniform granularity and high strength, and can be conveniently mixed with other nitrogen-phosphorus-potassium fertilizers.

The invention relates to a chickpea sprout extract used for reducing blood sugar and also relates to a preparation method and application of a chickpea sprout extract dispersible tablet used for reducing blood sugar. The preparation method of the chickpea sprout extract dispersible tablet comprises the following steps of: sprouting chickpeas for 3-4 days, picking sprouts, airing and then extracting with ethyl alcohol, adsorbing by virtue of a macroporous adsorption resin, carrying out reduced pressure concentration and drying, so as to obtain the chickpea sprout extract; then adding pharmaceutically acceptable filling agent, disintegrating agent and swelling property auxiliary materials into the chickpea sprout extract, mixing uniformly, making softwood by taking an ethyl alcohol solution as a wetting agent, pelletizing, drying, straightening granules, adding a lubricating agent, uniformly mixing, and tabletting, thus the chickpea sprout extract dispersible tablet is obtained. The chickpea sprout extract dispersible tablet obtained by adopting the preparation method has the characteristics of high disintegration speed, high active ingredient dissolution rate and good dispersion uniformity and can be applied to medicine used for treating or preventing diabetes or health-care food assisting to reduce blood sugar.

The present invention relates to a Chinese medicine Sangju Ganmao effervescent tablet for curing wind-heat common cold, headache, cough, mouth dryness and sore throat. Specially, it is a ring-shaped effervescent tablet made up by using 8 Chinese medicinal materials of mulberry leaf, chrysanthemum flower, bitter apricot kernel, forsythia fruit, peppermint and others. Said invention also provides its preparation method.

The invention relates to a modified starch adhesive for preparing a hollow capsule and a starch-base hollow capsule prepared from the modified starch adhesive, belonging to the field of food, medicines and the like. The modified starch adhesive for preparing the hollow capsule is prepared by mixing hydroxypropyl starch or acid-treated hydroxypropyl starch with a gelatinizer. The substitution degree DS of the hydroxypropyl starch or acid-treated hydroxypropyl starch is 0.1-0.93, and the gelatinization temperature is 25-60 DEG C. The modified starch adhesive can be heated in water to be gelatinated and colloidized to obtain the starch-base hollow capsule. The hydroxypropyl functional group is introduced to the starch molecules to modify the starch, thereby overcoming the intermolecular hydrogen bonding force of the starch, performing the toughening and reinforcing functions, effectively inhibiting starch from anabiosis, increasing the hydrophilicity of the starch molecules and lowering the gelatinization temperature; and thus, the starch-base hollow capsule has favorable disintegrability.