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Method for preparing fresh ginsengfreeze-dried oral instant preparation

A technology of oral instant and oral instant tablets, which is applied in food preparation, freeze-drying transportation, pharmaceutical formulations, etc., can solve the problem of undiscovered fresh ginseng extract, and achieve the effect of strong ginseng taste, more retention and good taste

Active Publication Date: 2015-07-22
北京同仁堂健康药业(辽宁)有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Freeze-dried preparations and literature reports of fresh ginseng extract have not been found so far

Method used

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  • Method for preparing fresh ginsengfreeze-dried oral instant preparation
  • Method for preparing fresh ginsengfreeze-dried oral instant preparation
  • Method for preparing fresh ginsengfreeze-dried oral instant preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] After washing, take 10kg of fresh ginseng and 25kg of pure water and use a colloid mill to grind at 20°C for 10 minutes, keep warm at 67°C and grind for 5 minutes, filter, squeeze the residue, combine the filtrate, put it into an ultra-high pressure equipment kettle, and increase the pressure to 550Mpa, keep it for 10 minutes to get ginseng extract, fill the ginseng extract into aluminum-plastic blisters, spray into liquid nitrogen for quick freezing, put it in a freeze dryer, quick freeze to -52°C, keep it for 2 hours, and vacuum to 1.5Pa, then raise the temperature of the plate layer to -40°C, maintain for 3 hours, raise the temperature to -30°C, maintain for 3 hours, until the sublimation drying is completed; then raise the temperature of the plate layer to 30°C, until the analysis and drying Film packaging, prepared into fresh ginseng freeze-dried oral instant tablets.

[0029] The total saponin content of ginseng was determined to be 3.6%, and the disintegration ti...

Embodiment 2

[0031] After washing, take 10kg of fresh American ginseng and 10kg of pure water and use a colloid mill to grind at 25°C for 20 minutes, keep warm at 70°C for 4 minutes, filter, squeeze the residue, combine the filtrate, put it into an ultra-high pressure equipment kettle, and raise the pressure to 500Mpa, keep it for 15 minutes to get the American ginseng extract, fill the American ginseng extract into a freeze-dried bottle, put it into a freeze dryer, freeze it to -55°C, keep it for 2 hours, vacuumize it to 2Pa, and then lower the plate temperature Raise the temperature to -40°C and maintain it for 3 hours, raise the temperature to -30°C and maintain it for 4 hours until the sublimation drying is completed; then raise the temperature of the plate layer to 30°C until the analysis and drying is completed, and prepare fresh ginseng freeze-dried oral instant powder .

[0032] The total saponin content of ginseng was determined to be 6.8%, and the disintegration time limit was 0....

Embodiment 3

[0034]Wash and cut 10kg of fresh American ginseng, 30kg of pure water, 500g of fresh dendrobium cut into small flakes, use a colloid mill to grind at 20°C for 12 minutes, keep warm at 65°C for 6 minutes, filter, and squeeze the residue. Combine the filtrates, put them into an ultra-high pressure equipment kettle, increase the pressure to 600Mpa, and maintain for 12 minutes to obtain the American ginseng extract, fill the American ginseng extract into a freeze-drying bottle, put it in a freeze dryer, and freeze it to -50°C. Keep it for 2 hours, evacuate to 1Pa, then raise the temperature of the plate layer to -40°C, maintain it for 4 hours, raise the temperature to -30°C, maintain it for 3 hours, until the sublimation drying is completed; then raise the temperature of the plate layer to 30°C, Until the analysis and drying are completed, it is prepared into a freeze-dried oral instant powder of Dendrobium ginseng.

[0035] The total saponin content of ginseng was determined to b...

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Abstract

The invention discloses a method for preparing a fresh ginsengfreeze-dried oral instant preparation, and belongs to the technical field of medicinalhealthcare products. The method for preparing the fresh ginsengfreeze-dried oral instant preparation comprises the following steps: adding pure water into fresh ginseng, grinding by using a grinding machine, filtering, squeezing the residues, combining the filtrate, feeding the filtrate into a high-pressure equipment kettle, boosting the pressure to be 500-600MPa, keeping the pressure for 10-15 minutes so as to obtain a ginseng extract, filling the ginseng extract into a freeze-drying bottle, putting into a freeze-drying machine for rapid freezing, vacuuming, and heating a plate layer until analysis drying is completed, thereby preparing the fresh ginsengfreeze-dried oral instant preparation. The fresh ginsengfreeze-dried oral instant preparation prepared by using the method has the characteristics of being highin disintegration speed, high in bioavailability, high in dissolution rate, small in nutrient component consumption, easy to absorb by human bodies, high in absorption speed and relatively small in volatile oil component loss.

Description

technical field [0001] The invention relates to a preparation method of fresh ginseng freeze-dried oral instant preparation, which belongs to the technical field of medicine and health products. Background technique [0002] Ginseng is an important traditional medicinal herb, generally including Panax ginseng (Latin name Panax ginseng C. A. Mey.) and American ginseng ( Panax quinquefolium L.) and Panax notoginseng ( Panax notoginseng (Burk.) F.H.Chen), ginseng medicinal materials contain a variety of physiologically active ingredients, including dozens of ginsenosides, polysaccharides, polypeptides and volatile components. Current research shows that ginseng has the functions of nourishing vitality, restoring pulse and solidifying, and nourishing the spleen. Tonify the lungs, promote body fluid and soothe the nerves. [0003] The currently known solid dosage forms of ginseng medicinal materials mainly include ordinary tablets, capsules, and pill dosage forms. General...

Claims

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Application Information

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IPC IPC(8): A61K36/258A61K9/19A23L1/29A61P1/14A61P9/00A61P1/00A61P11/00A61P25/20A23L33/00
Inventor 董英杰艾莉王会芳邹晓峰韩亚男李晓怡
Owner 北京同仁堂健康药业(辽宁)有限公司
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