507 results about "Intestinal absorption" patented technology

The present invention is directed to novel food products, e.g., nutritional food products and infant formula, which contain one ore more enzymes selected from lipase, protease, and amylase that have been formulated / stabilized to have sustained stability in an aqueous medium. Such formulations are intended to provide a greater degree of compliance based on their ability to be incorporated into aqueous media while avoiding unstable breakdown of the enzyme and large overdosing due to expected breakdown when exposed to an aqueous environment, including saliva. Further described in the invention are additives packaged with instructions for combination with an aqueous medium, and instructions for the administration of the resulting mixture to a subject. In certain embodiments, enzyme insufficient patients, e.g., infants and elderly persons, would find particular benefit from the food products described herein.

The invention discloses freshwater fish feed and a preparation method thereof. The feed comprises the following materials in percentage by weight: 5%-17% of import fish powder, 8%-22% of flour, 3%-16% of potato starch, 3%-18% of beer yeast, 5%-15% of bean pulps, 5%-15% of peanut pulps, 5%-10% of rape seed cakes, 2%-8% of corn powder, 3%-9% of cooked egg protein, 5%-8% of dried meat floss powder, 1%-2% of liquid phytase, 1%-3% of non-starch polysaccharase, 0.5%-1.9% of glutamine, 1%-2% of microecological preparation and 1%-3% of immune polysaccharides. The preparation process comprises a crushing step, a mixing step, a pelletizing step and a spraying step. The freshwater fish feed has the beneficial effects of being capable of well satisfying the nutrition needs of freshwater fish, improving the immunity of the freshwater fish, prompting intestinal absorption and improving the production performance of the freshwater fish.

The present application describes a composition for blood glucose control containing green tea extracts (GTE) with gallated catechins (GC) and macromolecule to prevent the intestinal absorption of GC.

The invention relates to the technical field of medicine, in particular to a stomach floating type pellet and a preparation method thereof. The stomach floating type pellet comprises a pellet core, a drug layer and a sustained-release layer; the density of the pellet is smaller than 1g / cm<3>, so that the drug can float in the stomach, sustainably release the drug ingredients; stomach floating type capsules can be prepared by loading the pellets into capsules. The preparation type is suitable for drugs mainly absorbed in the stomach, in particular to the drugs that are absorbed better in the stomach than in the enteric canal. When the drugs are prepared into stomach floating type pellets or stomach floating type capsules, compared with ordinary preparation, the times of administration is reduced and the relatively stable blood concentration of the drugs is kept in vivo, thus ensuring the sustained release of the drugs, improving the bioavailability and reducing the dosage. At the same time, as the stomach floating type pellet is a granose system, the drug release behavior is the collective behavior of each pellet, so that coating failure of a plurality of pellets can not lead to failure of the whole dosage, thus having higher safety. The sustained-release pellet is prepared by adopting general technique and is easy for realizing industrial production.

The invention relates to a method for preparing a mixed-type nucleotide feed additive from yeast cells and applications of the feed additive, which belong to the technical field of the preparation of nucleotide feed additives from yeast cells. The method comprises the steps: using yeast cells as raw materials and combining a homogenization method and a salt method to break yeast cell walls ; separating the yeast cell walls, protein and other insoluble substances by centrifugation and fractional isoelectric crystallization; specially collecting RNA precipitates at special isoelectric points to obtain wet and crude nucleic acid with the purity of 70 percent; dissolving the wet and crude nucleic acid in water, using high-activity phosphodiesterase from malt roots to carry out a high-efficiency directional enzymatic reaction; directly spraying, drying and crushing the solution after the enzymatic reaction to obtain the mixed-type nucleotide feed additive product comprising the protein content lower than 10 percent and four monosomic nucleotides (AMP, GMP, CMP and UMP) larger than 60 percent. After the feed additive is applied to animal feed, the intestinal absorption function of animals can be notably improved, the growth of the animals is stimulated, and the immune function, the antiviral capability and the anti-stress capability of the animals are improved.

The present invention relates to microorganisms for the treatment or the prevention of obesity or diabetes mellitus, which reduce the amount of monosaccharide or disaccharide which may be absorbed into human body by converting monosaccharides such as glucose, fructose, galactose et al. and disaccharides into polymeric materials which cannot be absorbed by the intestine, and relates to a pharmaceutical composition containing the said microorganisms.

Disclosed is a Lansoprazole sodium intestine-dissolving preparation, which is prepared from Lansoprazole sodium 15-30 parts, thinning agent 150-300 parts, moistening agent or binding agent 20-110 parts, crumbling agent 5-25 parts, lubricating agent 5-15 parts and coating agent 30-100 parts through the steps of disintegrating, sieving, mixing, tabletting, and dressing isolation layer.

The invention provides a food capable of treating diarrhea, which is mainly composed of special carbohydrates and combined with other nutritional ingredients for regulating the intestines and stomach. Mix one or more of commercially available carbohydrates such as rice flour, flour, edible starch, and edible dextrin at a certain temperature or fry for a certain period of time to make a burnt-yellow powder containing caramelized sugar; Baking yam, hawthorn, dark plum, kudzu root, cinnamon, Atractylodes macrocephala, licorice, clove, nutmeg, Poria cocos, barley, Huoxiang, amomum, jujube, white lentils and other Chinese herbal medicines that can strengthen the spleen and stomach, or Stir-fry until slightly yellow, grind into powder; add a certain amount of whey protein, probiotics, prebiotics, glutamine, vitamin A, vitamin B, vitamin B2 and salt. The fried or baked food for treating diarrhea of ​​the invention can be absorbed by the intestinal tract, is suitable as food for patients with diarrhea, and is easily digested and absorbed by patients, so that patients with diarrhea can recover as soon as possible without side effects and has stable curative effect.

The present invention relates to the use of a growth hormone (GH) secretagogue, such as a ghrelin-like compound, for the preparation of a medicament for the prophylaxis or treatment of ghrelin deficiency, and / or undesirable symptoms associated therewith, in an individual at risk of acquiring partial or complete ghrelin deficiency resulting from a medical treatment and / or from a pathological condition. The present invention also relates to use of a secretagogue compound for the preparation of a medicament for the prophylaxis or treatment of one or more of: loss of fat mass, loss of lean body mass, weight loss, cachexia, loss of appetite, immunological dysfunction, malnutrition, disrupted sleep pattern, sleepiness, reduction in intestinal absorption and / or intestinal mobility problems in an individual suffering from, or at risk of suffering from, ghrelin deficiency. Furthermore, the present invention relates to the use of a secretagogue, such as a ghrelin-like compound, for the production of a medicament for preventing weight increase in an individual either: a) being converted from a hyperthyroidic state to euthyroid state, or b) in remission from being converted from a hyperthyroidic state to euthyroid state.

The invention relates to a dendrobium candidum chewable tablet. The chewable tablet consists of dendrobium candidum fine powder and medicinal acceptable auxiliary materials, and is characterized in that: the particle diameter of the dendrobium candidum fine powder is 34-58 mum. The dendrobium candidum chewable tablet disclosed by the invention has high polysaccharide dissolution rate, and contributes to intestinal absorption of active ingredients; and the bioavailability of a preparation can be improved remarkably.

The invention provides a physiologically acceptable polymeric material having one or more ligands capable of binding to a receptor in a human or animal gut, said receptor being selected from the group consisting of carbohydrate, amino-acid, lipid and peptide receptors, characterised in that the polymeric material is substantially incapable of being absorbed by the gut, which is useful in the treatment of obesity or in the improvement of the bodily appearance of a human or animal by reducing its weight.

The invention relates to a through-rumen choline chloride microcapsule and the preparation technique thereof, and solves the problems that choline chloride has a poor effect through the rumen, ruminants have a low intestinal absorption rate and packing, storage and transportation are not easy. The technical proposal is as follows: choline chloride with a mass percentage of 35 to 40 percent is adopted as the main active ingredient and used as the core material, acrylics IV is used as the internal coating of the core material, chitosan is used as the external coating, and the mass of the internal and external coatings is both 3 to 5 percent of the mass of the core material. The through-rumen choline chloride microcapsule can guarantee that a good moisture resistance is ensured during packing, storage and transportation, deformation and damage fail to occur due to compression, the goal of a slow release can be achieved in the rumen and the intestinal absorption rate of choline chloride is improved.

The present invention relates to microorganisms for the treatment or the prevention of obesity or diabetes mellitus, which reduce the amount of monosaccharide or disaccharide which may be absorbed into human body by converting monosaccharides such as glucose, fructose, galactose et al. and disaccharides into polymeric materials which cannot be absorbed by the intestine, and relates to a pharmaceutical composition containing the said microorganisms.

The invention relates to a Niuhuangshangqing soft capsule and a preparation method thereof, as well as a quality control method of capsule contents. The Niuhuangshangqing soft capsule comprises contents and capsule shell. The contents include an extent of Chinese medicinal materials in Niuhuangshangqing prescription and a dispersion medium with a weight ratio of 1:(1-2), wherein, the dispersion medium is vegetable oil. The soft capsule is prepared by extracting effective components from Chinese medicinal materials in Niuhuangshangqing prescription in accordance with the properties of the effective components by using different modern extraction techniques and making into soft capsule. The soft capsule has embedding and masking effects, and can prevent volatilization loss of oil components and oxygenation or photodecomposition of effective components. The soft capsule also has the advantages of rapid disintegration, uniform dispersion, high bioavailability, good stability of effective components, low liability of moisture absorption, good air tightness, direct intestinal absorption after disintegration, masking of unpleasant odors of effective components, convenience for administration and carrying, and so on.

The invention discloses a mold removal agent for animal feed as well as a preparation method and an application of a mold removal agent. The mold removal agent comprises the following components in parts by mass: 50-150 parts of bacillus subtilis, 5-15 parts of lactobacillus acidophilus freeze-dried powder, 0.1-1 part of sodium selenite, 25-55 parts of vitamin E, 100-300 parts of feed active dry yeast, 5-15 parts of glucomannan, 50-150 parts of montmorillonite and 350-700 parts of modified hydration aluminosilicate. The mold removal agent prepared by the method is environment-friendly and pollution-free, has extremely strong adsorption capacity for various common mycotoxin, forms a stable compound, is not absorbed by intestinal tracts and is excreted from a body along with faeces. The mold removal agent disclosed by the invention can be used for detoxicating, inhibiting the growth of mildews, improving the immunity of animals and promoting the growth of the animals.

Nanoparticles, compositions, and methods for the improved uptake of active agents are disclosed herein. The compositions contain a monodisperse population of nanoparticles, preferably including an active agent, where the nanoparticles are formed from a polymeric material possessing specified bioadhesion characteristics. Following enteral administration, preferably oral administration, the nanoparticles exhibit total intestinal uptakes of greater than 20%, preferably greater than 45%, more preferably greater than 65%. When compared to uptake of the same composition in the absence of the bioadhesive polymeric material, the nanoparticles have significantly increased uptake with intestinal uptake of the increased by more than 100%, preferably even greater than 500%. Further disclosed herein is a method of producing multi-walled nanoparticles, as well as methods of using thereof. Multi-walled particles prepared using the method disclosed herein are useful for controlling the release of active agents.

The invention discloses a feed fermentation agent and a fermented feed, the feed fermentation agent includes the following components by mass: 20-25% of pichia pastoris, 15-20% of lactobacillus, 10-15% of enterococcus faecalis, 3-10% lactobacillus plantarum, 10-15% of cellobiose lactobacillus and 15%-25% a compound enzyme agent. The fermented feed is a fermented product of soybean meal, corn and wheat bran, mulberry-rich plants and a mixture of mulberry-rich plants and soybean meal by use of the feed fermentation agent, after fermentation of the soybean meal or corn or wheat bran and other traditional feed by use of the feed fermentation agent, harmful materials such as accumulated stool and the like cumulated in pig intestines can be decomposed and removed by cooperation of crude fiber in the traditional feed and microorganism, so that the intestinal absorption efficiency of nutrients can be provided.

The invention relates to a resveratrol oral administration drug delivery system prepared through the nanometer technology. The drug delivery system is made of the resveratrol and bearer material of wheat gliadin. By utilizing the characteristic that the nanometer granule is highly dispersed and that of biological adhesion of the bearer material, the contact area and contact time of the resveratrol and absorption region of the intestinal canal is increased, which can promote absorption of the small intestine. In addition, the resveratrol oral administration nanometer drug delivery system is distributed over the suitable auxiliary-material skeletal material to improve the dissolve velocity and degree of the resveratrol.

The invention discloses feed additive for improving cad pig growth performance and mixed batch. The feed additive comprises following ingredients by parts of weight: 23 to 25 of pericarpium citri reticulatae, 23 to 26 of hawthorn, 27 to 35 malt, 4 to 8 Chinese rhubarb, 15 to 23 Chinese yam, 0.001 to 0,002 Vb12, 9 to 11 chelate iron and 80 to 120 sodium butyrate. The additive is scientific and reasonable in proportion, can improve cad pig growth performance, improves feed conversion and increases hemoglobin content in blood. Fermented soybean meal containing active small peptide can be absorbed and utilized by intestinal tracts easily. The Chinese herb medicine mainly has the function of regulating qi, tonifying spleen and nourishing the stomach. The sodium butyrate can repair small intestine choria of pigs, increases recess depth, reduces potential of hydrogen (pH) in intestinal tracts and prevents harmful bacteria from breeding.

The invention discloses a health-care food for improving the moisture of skin and removing wrinkles, which is prepared by the following raw materials in parts by weight; 10-15 parts of collagen powder, 6-8 parts of soybean isoflavone, 3-5 parts of pearl powder, 3-5 parts of aloe extract, 3-5 parts of American ginseng extract, 3-5 parts of poria cocos extract, 3-5 parts of amur corktree bark extract, 2-3 parts of Chinese date, 1-2 parts of vitamin C powder, 3-5 parts of fructo-oligosaccharide, 3-8 parts of sodium carboxymethylcellulose, 1-5 parts of citric acid, 1-5 parts of malic acid and 5-20 parts of sucralose. The invention has the functions of internally expelling the toxin, tonifying the qi and nourishing the yin and replenishing the collagen lacked in human bodies by reasonably blending with the collagen powder, the soybean isoflavone, the pearl powder, the aloe extract, the poria cocos extract, the American ginseng extract, the amur corktree bark extract, the Chinese date and the vitamin C powder, thereby achieving the effects of water replenishing and wrinkle removal from inside to outside; and in addition, the raw materials of the fructo-oligosaccharide and the like are added, thereby the invention has the effects of adjusting tastes and promoting intestinal absorption.

The invention relates to liquid calcium soft capsules and a preparation method thereof. The inclusion of the soft capsules is prepared from the following raw materials in parts by weight: 50 to 80 parts of calcium carbonate, 0.0001 to 1 part of vitamin D3, 20 to 50 parts of soybean oil, and 15 to 30 parts of beeswax. The preparation method comprises the following steps of: preparing capsule bodies by using gelatin, glycerol and purified water as capsule body raw materials; mixing a mixture of the calcium carbonate, the vitamin D3, the soybean oil and the beeswax for 20 to 40 minutes, and slowly milling the mixture for 1 to 3 times through a colloid mill to obtain the uniformly mixed inclusion; and pressing, sizing, washing, drying, sorting and packing the inclusion and the capsule bodies, thus obtaining the liquid calcium soft capsules. Compared with the prior art, the liquid calcium soft capsules have the advantages that the calcium carbonate has the advantages of high calcium content, high intestinal absorption, high dissolubility, low price and the like compared with other calcium agents, so the soft capsules are beneficial to absorption of active ingredients; and the soft capsules can simultaneously supplement calcium and vitamin D, are convenient to administrate, improves the nutritional status of human bodies, and promotes the health of the human bodies.

The invention relates to a active bone peptide for treating and preventing osteoporosis and process for its preparation, which comprises the following steps: (1) cleaning bones of animal limbs, sterilizing, disintegrating, charging distilled water, controlling hydrolysis with proteinase, filtering the supernatant fluid, (2) degreasing the supernatant fluid, concentrating, ethanol extracting, filtering the supernatant fluid, (3) dealcoholizing the supernatant fluid, centrifugal filtrating, gathering the filtering medium, (4) making the active bone peptide into any one of the pharmacological dosage forms.

The present invention relates to a lactic acid bacterium isolated from human mother's milk, more precisely a Lactobacillus gasseri BNR17 strain that is isolated from Korean mother's milk and has excellent probiotic activity including acid resistance, bile acid resistance and antimicrobial activity and weight gaining inhibitory effect as well Again, the Lactobacillus gasseri BNR17 of the present invention has excellent acid resistance, bile acid resistance, enteric absorption activity and antimicrobial activity against pathogenic microorganisms, in addition to the weight gaining inhibitory effect by synthesizing indigestible polysaccharides from monosaccharides included in food taken and releasing the synthesized polysaccharides out of the body. Therefore, the strain of the invention, owing to such beneficiary effects, can be effectively used not only for the production of fermented milk, other fermented food products and animal feeds but also for the production of live cell products and food additives for preventing weight gaining.

Intestinal absorption is enhanced in short bowel syndrome patients presenting with colon-in-continuity by treatment with a GLP-2 receptor agonist, such as teduglutide.

The present invention provides compositions and methods for the administration of the compositions to mammals. The compositions comprise therapeutic agents and an intestinal absorption enhancing amount of one or more tight junction agonists. Tight junction agonists include zonulin and / or ZOT receptor agonists. Methods of the invention include orally administering compositions of the invention.

The invention provides a total nutrient formula food for patients with gastrointestinal malabsorption to eat, a specific total nutrient formula food or a non-total-nutrient formula food. According to the requirements of general principles of the special medical use formula food, the formula is developed by combining with the constitutive characters of the patients with gastrointestinal malabsorption and synthesizing with the research results of advanced physiology, medicine, nutriology, clinical application and the like in Harvard University at present according to the essence theories (simultaneous recuperation of the liver, the spleen and the kidneys) of supplement in digestion and balanced recuperation in the traditional Chinese medicine. According to the total nutrient formula food, essence of more than ten medicinal and edible traditional Chinese medicine extracts, a plurality of probiotics and prebiotics are taken as main raw materials, and oligopeptide, amino acid, water-soluble dietary fiber, multi-vitamin and composite minerals are taken as auxiliary materials, the total nutrient formula food not only can meet the nutritional requirements of the patients with gastrointestinal malabsorption as a single nutrient source, but also can have the efficacies of invigorating the stomach and helping digestion, warming the middle warmer and rectifying the spleen, tonifying the stomach and promoting fluid, tonifying the spleen and nourishing the stomach, helping digestion and eliminating indigestion, resolving dampness and activating the stomach, and preventing and treating gastrointestinal malabsorption.

The invention discloses a probiotic fermentation dendrobium officinale protocorm composition and a preparation method thereof. The preparation method comprises the steps that dendrobium officinale protocorm is dried, smashed into powder and immersed with water, glucose, peptone, yeast extract, yeast powder and a sweetening agent are added, inorganic salt is added, probiotic fermentation treatment is carried out after sterilization, polydextrose and fructo-oligosaccharide syrup are added, and the composition is prepared. The dendrobium officinale protocorm is subjected to high-pressure and high-temperature extraction after being smashed, and the extracting rate of effective ingredients of the raw materials is improved; multiple strains of probiotics are utilized for batch fermentation, the effective ingredients become active matter capable of being easily absorbed by the intestinal tract, and the utilization rate is improved. The composition has the effects of improving immunity, resisting tumor, oxidation, scavenging free radical, lowering blood fat and blood pressure, adjusting balance of intestinal flora, improving the gastrointestinal function and the like.

The invention discloses a preparation method of a dendrobium officinale fungus fermented product, the fermented product and an application of the fermented product. The preparation method of the dendrobium officinale fungus fermented product includes the steps of dendrobium officinale preparation, strain activation, liquid seed culture, dendrobium officinale fungus fermentation and fermented product processing. The fermented product is obtained by the preparation method of the dendrobium officinale fungus fermented product. The application comprises that the dendrobium officinale fungus fermented product is used for preparing food, health food, cosmetics and / or drugs. Dendrobium officinale is fermented with medicinal and edible fungi containing cellulose and other substances, dendrobium cellulose and the like are decomposed into small-molecular carbon sources, and the beneficial ingredients of the dendrobium officinale are retained; and moreover, the fermented product has mellow mouthfeel, has both faint scent of the dendrobium officinale and unique flavor of the fungi, also is rich in fungal polysaccharides, saponins, polyphenols, flavonoids and other active substances; the effective ingredients are easily absorbed in intestines, and has the efficacies of improving immunity, resisting tumor, resisting oxidation, reducing blood fat and blood pressure, regulating the balance ofintestinal microflora and the like.