The invention discloses a nutrition powder for resisting disease and strengthening body and a preparation method of the nutrition powder. The nutrition powder is characterized by comprising the following raw material components in the formula: brown rice, wheat, black soya bean, small red bean, mung bean, fresh flax, buckwheat, seed of Job tears, hyacinth bean, schisandra chinensis, brown rice bud, rice sprout and malt, bee pollen, royal jelly, barley malt, millet, folium mori, rose lobular, sweet potato leaves, agropyron, barley grass, stevia rebaudianum, chamomile, pine needle, kelp, cabbage, red cabbage, celery, barbados aloe, asparagus, mint, burdock, broccoli, lecithin, angelica keiskei, nori, pawpaw, carrot, radish, alfalfa, pumpkin and active calcium. The nutrition powder ( non-disease-fighting drug) has functions of preventing disease and strengthening body, producing toxin, eliminating pathogens, regulating internal organs of the body, improving body metabolism, strengthening immunity, regulating body internal and external balance, strengthening vessel elasticity, preventing disease and strengthening body.