41 results about "Bitter melon" patented technology

Use of a bitter melon exosome and an oral medicament prepared therefrom. The bitter melon exosome obtained from the bitter melon juice can be used for preparing a pharmaceutical formulation embedding a protein, a polypeptide, a small molecule peptide, a nucleic acid, or a small molecule compound. The compositions of the oral medicament of the present invention comprise the bitter melon exosome and an active pharmaceutical ingredient encapsulated in the bitter melon exosome. The bitter melon exosome is suitable for preparing a drug that is easily damaged by the gastrointestinal tract and is mostly administered by means of an injection route into an oral agent, and the oral agent can produce a similar therapeutic effect to that of the injection administration route by oral administration, and is convenient to use. The extraction method for the bitter melon exosome is simple and has a low cost. Moreover, the bitter melon exosome has no immunogenicity, has relatively high biocompatibility and biosafety, and has relatively strong tolerance to gastric acid and digestive tract proteolytic enzymes, and intestinal barrier permeability.

The application discloses application of tomato saponin in preparation of a uric acid reducing composition and belongs to the technical field of biological medicine. The uric acid reducing composition comprises 80-240 parts of tomato saponin, 50-120 parts of momordica charantia saponin, 25-100 parts of fruit and vegetable extract, 10-20 parts of schizonepeta turczanovii extract, 10-20 parts of terminalia catappa leaf extract and 40-100 parts of soluble dietary mixture. Animal experiment verification shows that the composition can effectively reduce blood uric acid level and improve kidney function through the synergistic effect of multi-target points such as inhibition of uric acid synthesis, promotion of uric acid excretion, anti-inflammatory kidney protection and metabolic regulation, and a safe and efficient solution is provided for hyperuricemia.

This invention discloses a low-allergen compound oral liquid for middle-aged and elderly people that protects the liver, stabilizes blood pressure, blood sugar, and blood lipids, combats aging, aids sleep, and prevents Alzheimer's disease. It belongs to the field of food and medicine homology health food technology. The invention uses kudzu root extract, Japanese raisin tree fruit extract, mulberry leaf extract, jujube seed saponins, Acer truncatum seed oil (nervonic acid), blueberry anthocyanins, bitter melon small molecule peptides, wolfberry polysaccharides, γ-aminobutyric acid, and chrysanthemum flavonoids as core active ingredients, refined with a prebiotic system. This invention achieves comprehensive conditioning effects for middle-aged and elderly people through the synergistic action of five pathways: liver protection and metabolism, vascular regulation, anti-oxidation and anti-aging, nerve calming, and brain nerve repair. It simultaneously nourishes and protects the liver, stabilizes blood pressure, blood sugar, and blood lipids, delays aging, improves intractable insomnia, enhances memory, slows brain atrophy, and prevents Alzheimer's disease. This formula strictly avoids eight common allergens, is pure and mild, and contains no irritating additives, making it suitable for long-term use by middle-aged and elderly people with weak constitutions. This product is an oral liquid formulation, with small molecule extraction, strong permeability, rapid absorption, low gastrointestinal burden, stable production process, and high safety. It has extremely high clinical promotion value and industrialization prospects.

The invention discloses application of bitter gourd exosomes in regulating intestinal flora. The method comprises the following steps: establishing an Alzheimer's disease mouse model, injecting the extracted balsam pear exosome into the mouse body in a gavage manner to serve as an experimental group drug, taking normal saline as a model negative control group, detecting the change of the intestinal flora of the AD mouse by applying a 16S amplicon sequencing principle, and detecting the change of the intestinal flora metabolite of the AD mouse by applying an LS-MS technology. An open field experiment, a nesting experiment and a water maze experiment are adopted to verify the treatment effect of the balsam pear exosome on AD mouse intestinal flora and metabolic level changes thereof. Results prove that the bitter gourd exosome extracted by the invention can effectively improve the intestinal flora micro-ecology of AD mice; the compound can be used for preparing a microecological preparation for regulating intestinal flora of neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, different types of spinal cerebellar ataxia and the like and diseases such as cerebral apoplexy, cerebral injury, epilepsy, tumor and the like.

The present application provides a blood sugar regulating health care composition, which utilizes the combination of effective components in the fruit pulp and seeds of Momordica balsamifera, and the effective components of Chinese herbal medicines, to help the blood sugar of type 2 diabetes patients to decrease steadily. The compound food composition contains 20-60wt% Momordica balsamifera component, 5-20wt% Momordica balsamifera seed component, 1-20wt% cinnamon component, 1-15wt% monk fruit component, and 1-10wt% licorice component. In addition, the blood sugar regulating health care composition can also regulate the comprehensive indexes of patients with high blood lipids, high cholesterol, abnormal liver metabolic enzymes, and abnormal uric acid at the same time.

The invention provides a composite plant polypeptide composition for reducing blood glucose, repairing cells, resisting oxidation and enhancing immunity as well as a preparation method and application thereof, and belongs to the technical field of biology. The invention provides a composition. Comprising a protein peptide composed of millet protein peptide, soybean protein isolate peptide, whey protein peptide and sea buckthorn protein peptide, dietary fiber composed of chia seed powder and konjaku flour, a probiotic compound composed of bifidobacterium lactis BB-12 and lactobacillus rhamnosus LGG, fructo-oligosaccharide, balsam pear peptide, a cyclocarya paliurus extract, a corn stigma extract, a mulberry leaf extract, a vitamin E extract, a vitamin E extract, a vitamin E extract, a vitamin E extract, a vitamin E extract and a vitamin E extract. The extract mixture is composed of a radix puerariae extract, a rhizoma polygonati polysaccharide extract, a moringa oleifera leaf extract and leech powder, and the vitamin mineral substance mixture is composed of other functional components. The composition provided by the invention is matched with various proteins, dietary fibers, probiotics, prebiotics, plant extracts, vitamins, minerals, other functional components and the like, so that the purpose of effectively and synergistically improving the conditions of diabetes and nephropathy from multiple targets and multiple ways is finally achieved.

The application belongs to the technical field of plant cultivation, and particularly relates to a cultivation method of a strong female variety of Momordica charantia. The cultivation method of the strong female variety of Momordica charantia comprises the following steps: S1. planting: planting the strong female variety and the weak female variety according to a proportion; S2. fruit retention: starting from the first female flower, two batches of fruits are retained on the main vine, four fruits are not pollinated, and two fruits are selected and retained on each side vine between the two batches of fruits of the main vine; S3. pruning; S4. water and fertilizer management; and S5. harvesting. The cultivation method of the application optimizes the planting proportion, fruit retention method, pruning and water and fertilizer management of the strong female variety and the weak female variety, creates the meeting of female flowers and male flowers in the early stage, solves the problem that the strong female variety has no male flowers to pollinate in the early stage, achieves the effects of concentrated pollination and concentrated harvesting, improves the commodity rate of early fruits, more accurately harvests the early yield, and saves the cost.

This invention discloses an anti-porcine reproductive and respiratory syndrome virus (PRRSV) preparation and its preparation method. The anti-PRRSV preparation comprises traditional Chinese medicine, excipients, and probiotics. The traditional Chinese medicine includes: mustard greens, thistle, bitter melon, and barley sprouts. The excipients include: soybean meal, wheat bran, and molasses. The probiotics include: Bacillus subtilis, Enterococcus faecium, and Saccharomyces cerevisiae. By feeding pigs suffering from PRRSV with the anti-PRRSV preparation of this invention, PRRSV can be antagonized, improving the recovery rate of PRRSV-affected pigs and reducing the mortality rate. The anti-PRRSV preparation of this invention can be used as an antagonist of PRRSV. Furthermore, the anti-PRRSV preparation of this invention can also be used as a feed additive for the prevention or treatment of PRRSV in pigs.

This invention provides a method for preparing a metformin compound hypoglycemic oral solution, relating to the pharmaceutical field, comprising: step S1, pretreatment of traditional Chinese medicine components; step S2, enzymatic hydrolysis of the first group of traditional Chinese medicine components; step S3, supercritical extraction; step S4, preparation of mixed traditional Chinese medicines; step S5, preparation of inclusion complex; step S6, compound formulation; and step S7, post-processing. This method synergistically combines extracts from seven traditional Chinese medicines—bitter melon, phellodendron bark, astragalus root, kudzu root, rehmannia root, ginseng, and privet fruit—with metformin hydrochloride to form a metformin compound hypoglycemic oral solution, balancing the synergy, safety, and stability of traditional Chinese and Western medicines, thereby improving hypoglycemic effects while reducing the incidence of gastrointestinal adverse reactions to metformin.

The present application belongs to the technical field of plant molecular biology and plant genetic engineering, and particularly relates to the regulation of McCAB1 gene on the peel color of Momordica charantia. The present application finds that the McCAB1 gene from the green Momordica charantia B07 has a regulation on the fruit color of Momordica charantia. After the McCAB1 gene is heterologously overexpressed, the peel color of Momordica charantia is obviously deepened and green, and the chlorophyll content is also significantly improved. The present application firstly determines that the McCAB1 gene from the green Momordica charantia B07 is a key gene for the regulation of Momordica charantia fruit color, fills the research gap in the field of molecular regulation of Momordica charantia fruit color, and provides a core target for analyzing the formation mechanism of Momordica charantia fruit color. In addition, the McCAB1 gene can be used for the identification of Momordica charantia peel color or directed for the breeding of Momordica charantia fruit appearance quality, helps to cultivate Momordica charantia varieties with excellent color and luster to meet the market demand, and also provides a reference for the improvement of fruit color of Cucurbitaceae crops, and has a wide application prospect.

The invention discloses a KASP molecular marker linked with a first female flower node character of bitter gourd and application of the KASP molecular marker, the KASP molecular marker is located at the 22054848 site of a No.4 chromosome of a bitter gourd genome, and the basic group at the site is A or C. The KASP molecular marker and the amplification primer thereof disclosed by the invention can be used for effectively detecting the character of the first female flower node of the balsam pear, are beneficial to screening a balsam pear variety with a low first female flower node, and have important guiding significance for molecular marker-assisted breeding of the balsam pear.

A fermented natural substance having nitric oxide metabolites fixated and stabilized therein is produced by a process including adding a fermentative strain to nitrogen-containing natural substance and carrying out fermentation by a batch fermentation process. The nitrogen-containing natural substance is at least one selected from the group consisting of lettuce, Sedum sarmentosum, spinach, blueberry, dandelion, pomegranate, cabbage, garlic, Morinda citrifolia, onion, soybean, bean sprout, mulberry leaf, Momordica charantia, Rubus coreanus, Houttuynia cortada, aronia, Humulus japonicus, Coptis chinensis, hijiki, hooker chive, mushrooms, calamus, wild spinach (Seomcho), Chinese cabbage, kelp, apple, mugwort, orange, salmon testis, abalone shell, shellfish shell, cricket, silkworm, Rehmannia glutinosa, and Shipjeondaebo-tang. to Bacillus sp., Bifidobacterium sp., Enterococcus sp., or Lactobacillus sp.

The invention provides a pharmaceutical composition as well as application and a medicament thereof. The pharmaceutical composition comprises 5%-85% of a gymnema sylvestre extract, 5%-85% of a balsam pear extract, 5%-85% of a turmeric extract and 5%-85% of a wood orange extract. % is the mass percentage of each component in the pharmaceutical composition. The pharmaceutical composition provides significant benefits in managing diabetes, hyperlipidemia and associated metabolic disorders.

The invention discloses anthocyanin enzyme wine and a brewing method thereof, and relates to the technical field of fruit wine brewing. The main material is jaboticaba in a whole fruit form; the auxiliary materials comprise polycrystalline rock sugar, honey, rosmarinic acid and a balsam pear peptide extract; the brewing method comprises the following steps: cleaning and drying the main material jaboticaba; putting the main material jaboticaba which is cleaned and drained and the soaking auxiliary material into a soaking container together, adding the base liquor, sealing the soaking container, and soaking for 90-150 days; and after the soaking time is over, filtering and collecting filtrate. Through the unique whole-fruit treatment of the jaboticaba and the brewing process of soaking the auxiliary materials, the brewed jaboticaba fruit wine not only completely retains natural nutritional ingredients such as anthocyanin of the jaboticaba, but also has strong fruity flavor, mellow taste and stable quality; therefore, the problems of nutrition loss, difficulty in fermentation control, poor taste and flavor and the like in the existing jaboticaba wine brewing technology are solved.

This invention discloses the application of bitter melon-derived nanovesicles in the preparation of brain-targeted drugs, belonging to the field of biomedical technology. Specifically, this invention discloses that bitter melon-derived nanovesicles, used as carriers to load active substances, can be orally administered to deliver the active substances to the brain in a targeted manner, avoiding the inconvenience and risks of injection administration and providing a more convenient and more compliant drug delivery method for the treatment of brain diseases. Furthermore, bitter melon-derived nanovesicles have the advantages of good biocompatibility, no immunogenicity, safe metabolism in vivo, and long-term use.

The invention relates to a composition containing i) a DPP-4 inhibitor selected from an extract of dandelion (Taraxacum officinale), an extract of white mulberry (Morus alba), an extract of bitter melon (Momordica charantia), a hydrolysate of yeast (Saccharomyces cerevisiae), an extract of garlic (Allium sativum), an extract of grape (Vitis vinifera), an extract of turmeric (Curcuma longa), an extract of horseradish tree (Moringa oleifera) and an extract of fenugreek (Trigonella foenum-graecum); and ii) a GLP-1 analogue selected from a hydrolysate of yeast (Saccharomyces cerevisiae), a white mulberry (Morus alba) extract, a yerba mate (Ilex paraguariensis) extract, an Arabica coffee (Coffea arabica) extract, a purslane (Portulaca oleracea) extract, a bitter melon (Momordica charantia) extract, a lager flower (Lagerstroemia speciosa) extract, an apple (Malus domestica) extract, a cinnamon (Cinnamomum verum) extract and a fenugreek (Trigonella foenum-graecum) extract; and iii) a GLP-1 secretion enhancer selected from inulin, gum arabic, an extract of bitter melon (Momordica charantia), an extract of purslane (Portulaca oleracea), an extract of common barberry (Berberis vulgaris), an extract of Arabica coffee (Coffea arabica), an extract of Siberian angelica (Angelica dahurica), an extract of turmeric (Curcuma longa) and an extract of fenugreek (Trigonella foenum-graecum), where at least one ingredient is selected from each group i)-iii) and a total of at least three different ingredients are selected.

This invention provides a yin-nourishing and blood-tonifying medicinal composition, its preparation method, and its application, belonging to the technical field of traditional Chinese medicine compositions. The active ingredients of this composition are prepared from the following raw materials in parts by weight: Astragalus membranaceus 2-3 parts, Angelica sinensis 12-18 parts, Crataegus pinnatifida 2-3 parts, Glycyrrhiza uralensis 2-5 parts, Chrysanthemum indicum 5-9 parts, Melon japonica 20-30 parts, Lemon 15-19 parts, Fine corn flour 2-3 parts, and Whole milk powder 40-44 parts, wherein the weight ratio of Angelica sinensis to Astragalus membranaceus is (6-9):1. The composition of this invention can be prepared into various oral preparations using conventional pharmaceutical processes. The preparation process is stable and controllable, suitable for industrial production. This composition possesses the effects of nourishing yin and blood, strengthening the spleen and promoting digestion, is safe with no toxic side effects, and has an excellent taste. It can be used to prepare drugs for treating and improving yin and blood deficiency syndromes, and has good clinical application and industrialization prospects.

This invention relates to the field of food processing technology and discloses a meal replacement powder composition with hypoglycemic activity and its preparation method. The meal replacement powder uses buckwheat flour, yam flour, bitter melon flour, konjac oligosaccharide, polygonatum powder, and hawthorn powder as raw materials, with an optimized ratio of 2.00g buckwheat flour, 1.00g yam flour, 0.50g bitter melon flour, 0.40g konjac oligosaccharide, 0.40g polygonatum powder, and 0.45g hawthorn powder. The preparation method includes raw material pretreatment and precise ingredient mixing steps. The meal replacement powder of this invention is rich in total polysaccharides, total flavonoids, and total phenolic active ingredients. Its in vitro α-glucosidase inhibition rate is similar to that of acarbose, and its α-amylase inhibition rate is superior to that of acarbose. With a GI value of 53.92 (low GI food), it can effectively delay the rise in postprandial blood glucose, meeting the blood sugar control needs of people with prediabetes. The process is simple, the raw materials are natural, and it has the potential for large-scale industrialization.

This invention provides a compound composition for regulating glucose and lipid metabolism in diabetes and its application, belonging to the fields of medicine, food, and health products. The composition comprises an enzymatically hydrolyzed extract of Polygonatum sibiricum, a compound extract of traditional Chinese medicine including Astragalus membranaceus, ginseng, mulberry leaf, cinnamon, white kidney bean, and bitter melon, probiotics including Lactobacillus rhamnosus and Bifidobacterium bifidum B11, hydrolyzed collagen peptides, and tagatose, scientifically formulated according to the principles of traditional Chinese medicine. This composition can comprehensively regulate the multidimensional pathological characteristics of diabetes, such as glucose and lipid metabolism disorders, chronic inflammation, and weight loss, exerting a synergistic effect. Its hypoglycemic, lipid-regulating, anti-inflammatory, and weight-recovery-promoting effects are significantly better than the sum of the individual effects of each component. It can also significantly improve serum free fatty acid, fasting insulin, and inflammatory factor levels, providing a new approach for developing safe and effective adjunctive treatment products for diabetes.

The invention relates to the technical field of health food, and discloses a composition for sobering up, assisting in lowering lipid and improving intestinal tracts and a preparation method, the composition comprises the following components in parts by weight: 40-60 parts of rubus stems and leaves, 3-6 parts of oldenlandia diffusa, 1-3 parts of sculellaria barbata, 0.5-2 parts of balsam pear, 0.5-2 parts of radix bupleuri, 0.5-2 parts of pericarpium citri reticulatae, 0.5-2 parts of elecampane, 0.5-2 parts of raw hawthorn and 0.5-2 parts of semen plantaginis. The preparation method comprises the steps of raw material crushing, enzymolysis extraction, alcohol extraction, water extraction, spray drying and the like. Experimental verification shows that the composition has multiple effects of prolonging the drunkenness latency period, accelerating ethanol metabolism, reducing serum transaminase, regulating blood lipid indexes, improving intestinal peristalsis and flora structures and the like, and acute toxicity tests prove that the composition is high in edible safety. The composition disclosed by the invention can be used for preparing health-care foods with the effects of dispelling the effects of alcohol, assisting in lowering lipid and improving intestinal functions.

The application discloses a KASP molecular marker related to a balsam pear fruit weight character and application thereof, wherein the KASP molecular marker is located at position 27048107 of chromosome 8 of a balsam pear genome, and a base at the position is T or C. It is found that the KASP molecular marker is related to the balsam pear fruit weight character, and high-throughput, rapid and accurate identification of balsam pear fruit weight types can be realized at a seedling stage by using the KASP molecular marker and an amplification primer thereof, different fruit weight balsam pear germplasm resources are screened, effective technical support is provided for balsam pear molecular breeding, and the application has important application value.

The invention discloses a composition for losing weight, reducing fat, burning fat and controlling sugar as well as a preparation method and application thereof. The composition is composed of coconut components, coffee powder, cinnamon extract, clinacanthus nutans extract, L-carnitine, guarana extract, balsam pear extract, turmeric powder, psicose and other raw materials, all the components have a synergistic effect, carbohydrate digestion and glucose absorption are delayed by inhibiting the activity of glucosidase and amylase in the intestinal tract, and the effects of improving the immunity of the intestinal tract and improving the immunity of the intestinal tract are achieved. Meanwhile, insulin sensitivity and glucose tolerance are improved, so that accurate glucose control is achieved; secondly, by inhibiting differentiation of precursor fat cells, fat accumulation is reduced from the source, and effective lipid lowering is achieved; finally, the fat metabolism rate is accelerated by promoting the fat to be transferred into mitochondria, so that the fat is efficiently combusted, and finally the purposes of losing weight, reducing fat, combusting fat and controlling sugar are achieved. The traditional Chinese medicine composition can be prepared into various dosage forms, is suitable for people who are obese, hyperlipidemia, hyperglycemia and people who need to control body weight for slimming management, and has a wide application prospect.

The invention discloses a composition with multiple hypoglycemic mechanisms. The composition comprises a membrane separation balsam pear polysaccharide extract, a membrane separation balsam pear saponin extract, a mulberry leaf extract, a momordica grosvenori extract and inulin, the membrane separation balsam pear polysaccharide extract and the membrane separation balsam pear saponin extract have an inhibition effect on the key enzyme fructose-1, 6-diphosphatase in the gluconeogenesis path; the mulberry leaf extract and the inulin have an inhibition effect on a key enzyme alpha-glucosidase in a sugar absorption path; the momordica grosvenori extract and the inulin enhance the insulin sensitivity; the invention further discloses a preparation method of the composition with the multiple hypoglycemic mechanisms. According to the invention, through synergistic interaction of triple pathways for inhibiting gluconeogenesis, inhibiting sugar absorption and improving insulin sensitivity, a dual hypoglycemic mechanism of'blocking endogenous sugar generation from a source and inhibiting exogenous sugar absorption from a terminal 'is formed, and the hypoglycemic efficiency is obviously improved compared with that of a single mechanism formula.

The invention belongs to the technical field of plant molecular biology and plant genetic engineering, and particularly relates to a regulating effect of an McCAB1 gene on the color of bitter gourd peel. Research finds that the McCAB1 gene derived from the green balsam pear B07 variety has a regulation effect on the color of balsam pear fruits. After the McCAB1 gene is subjected to heterologous overexpression, the peel color of the balsam pear is obviously deepened and greened, and the chlorophyll content of the balsam pear is also obviously improved. According to the invention, the McCAB1 gene from green balsam pear B07 is determined as a key gene for regulating and controlling the fruit color of the bitter gourd for the first time, the research blank in the field of molecular regulation and control of the fruit color of the bitter gourd is filled, and a core target is provided for analyzing a fruit color forming mechanism of the bitter gourd. Besides, the McCAB1 gene can be used for bitter gourd pericarp color identification or oriented bitter gourd fruit appearance quality breeding, the cultivation of bitter gourd varieties with excellent color is assisted to meet the market demand, reference is provided for fruit color improvement of cucurbitaceae crops, and the application prospect is wide.

The invention relates to the technical field of green prevention and control of agricultural pests, in particular to a female bactrocera cucurbitae attractant based on volatile matters of bitter gourd fruits and leaves and application of the female bactrocera cucurbitae attractant. The active components of the female bactrocera cucurbitae attractant come from volatile matters of fruits and leaves of bitter gourds, and comprise 4-terpilenol, verbenol, alpha-terpilenol, capraldehyde, beta-caryophyllene and perillaldehyde. The main components of the female bactrocera cucurbitae attractant are all derived from natural plant volatile matters, the attractant is environment-friendly, a foundation is laid for field monitoring of bactrocera cucurbitae, and a new thought is provided for green prevention and control of bactrocera cucurbitae.

The enzyme takes a low glycemic index as a core design target, adopts three-stage secondary fermentation, and combines low-temperature slow-release enzymolysis, microcapsule targeted slow release and prebiotics synergistic interaction mechanisms, so that the enzyme has the advantages of low glycemic index, low glycemic index, high glycemic index, high glycemic index, high glycemic index, high glycemic index, high glycemic index, high glycemic index and high glycemic index. The formula of the health-care food comprises low-GI fruit and vegetable freeze-dried powder, a high-activity balsam pear saponin compound, mulberry leaf flavone micro-capsules, resistant starch-inulin composite prebiotics, a nattokinase-alpha-glucosidase inhibitory peptide (AGI-P) synergistic system, and gastric acid-resistant lactobacillus plantarum (Lactobacillus plantarum delta ldh-1) subjected to gene editing, and the health-care food is prepared from the low-GI fruit and vegetable freeze-dried powder, the high-activity balsam pear saponin compound, the mulberry leaf flavone micro-capsules, the resistant starch-inulin composite prebiotics and the nattokinase-alpha-glucosidase inhibitory peptide (AGI-P) synergistic system. Through the three-stage process of mother liquor anaerobic fermentation, sub-liquor aerobic fermentation and microencapsulation three-time aging, the bioavailability of active ingredients is improved by 3.2 times, the postprandial blood sugar peak value of the type 2 diabetes mellitus patient can be reduced by 41.7% through clinical verification, the risk of hypoglycemia is avoided, and the clinical application prospect is wide. The invention solves the problems of high sugar increasing load, easy inactivation of active components, low intestinal colonization rate and the like of the existing enzyme, and is suitable for long-term nutrition intervention of diabetics.

To provide a method for diluting, with water, an ethanolic extract of bitter melon (Momordica charantia) leaves, capable of suppressing formation of deposition as much as possible; and to provide a method for making the ethanolic extract of bitter melon leaves oil-soluble.SOLUTION: There is provided a method for diluting an ethanolic extract of bitter melon (Momordica charantia) leaves by adding water to the ethanolic extract of the bitter melon leaves, with a water extract of Nemacystus decipiens added thereto. There is provided also a method for adding an emulsifier and lecithin to the ethanolic extract of bitter melon leaves, with the water extract of Nemacystus decipiens added thereto, and further preparing an emulsion with oil added thereto to make the ethanolic extract of bitter melon leaves oil soluble with the emulsion added in the oil.SELECTED DRAWING: None

A hair enhancing composition for topical application to the scalp, brows, lashes, as well as areas of the face and body of an adolescent or adult human on which more, thicker, fuller and / or denser hair is desired, the composition comprised of a tropoelastin homologous polypeptide, and either or both of a hepatocyte growth factor homologous polypeptide and / or Momordica charantia fruit extract.

1. Name of the product in this design: Packaging Bottle (Rock Sugar Bitter Melon 2025). 2. Intended use of this design: This design is intended to be used as a container for holding liquids such as water or beverages. 3. The key design elements of this product are the combination of shape, pattern, and color. 4. The image or photograph that best illustrates the design's key features: the front view. 5. The design for which protection is sought includes color.

The application discloses application of a dendrobium extract in preparation of a medicine for treating type 2 diabetes, and mainly relates to the technical field of dendrobium. Specifically, the application provides a medicine for treating type 2 diabetes and containing the dendrobium extract, improves stability of components in the medicine for treating type 2 diabetes in an acid, neutral or alkaline environment, and slows down blood sugar increase. Compared with the prior art, the medicine for treating type 2 diabetes prepared by the application takes the dendrobium extract as a core, is matched with a synergistic emulsion, a rhizoma polygonati extract, a fructus corni extract, a salvia miltiorrhiza extract, a momordica charantia extract, vitamin B and trace elements of chromium, and through cooperation with traditional Chinese medicine components, can synergistically regulate blood sugar metabolism, enhance insulin sensitivity and improve microcirculation, can stabilize blood sugar, improve insulin resistance and lipid metabolism, improve immunity and cardiovascular function, and provides a safe and effective medicine for prevention and treatment of type 2 diabetes.