The invention discloses a novel Shatian pomelo tea vinegar drink, which comprises the following raw materials: Shatian pomelo pulp, Shatian pomelo peel, golden camellia, nutmeg, dark plum, semen plantaginis, licorice, hovenia dulcis thumb, persimmon leaf, Chinese olive, semen lablab album, radix sophorae flavescentis, galangal, orange peel, amomum tsao-ko, grape vinegar, ginkgetin, potassium iodide, carboxymethylcellulose sodium, agar, polyvinyl sodium, sodium alginate, a DuPont EEA2112AC compatilizer, a food-grade antioxidant BHT, locust bean gum, carthamin yellow, nisin, trisodium glycyrrhizinate, glucose, fructose, Thaumatin, vitamin A, vitamin C, vitamin D, isoleucine, lysine, threonine, tryptophan, iron element, manganese element, chromium element, copper element, ethyl-furfuryl fumarate, potassium inosinate, potassium guanylate, sodium L-glutamate, 9-cycloheptadecanone, hydroxycitronellal, ionone and vanillin. The drink provided by the invention can effectively break down alcohol, thus relieving damage of alcohol to the nervous system, etc.