30results about How to "Reserved function" patented technology

The invention discloses a curcumin-loaded brain-targeted drug delivery system as well as a preparation method and application thereof. The delivery system comprises a carrier macrophage and a curcumin drug, the curcumin nano-drug is prepared by encapsulating curcumin with a lipoic acid modified cyclodextrin conjugate, then macrophages and the curcumin nano-drug are mixed, and co-incubation is carried out, so that the curcumin nano-drug is constructed. The brain-targeted macrophage drug delivery system loaded with curcumin is a multifunctional composite drug with brain targeting property for treatment of cerebral arterial thrombosis. A brain-targeted macrophage drug delivery system loaded with the curcumin nano-drug gathers in cerebral apoplexy tissues, phenotypic transformation of inflammatory microglial cells is promoted, and a pro-inflammatory microenvironment is improved; the oxidative stress pressure of the stroke part is improved; the two effects promote each other, the stroke microenvironment is improved, the functions of neuronal cells are saved, the synergistic nerve protection effect can be achieved in the aspect of treating ischemic cerebral apoplexy, and potential safety hazards are reduced.

This invention discloses a fully decentralized multi-committee attribute-based encryption method, belonging to the field of information security. It modifies the attribute organization into a committee composed of multiple nodes and designs the committee initialization, attribute key issuance and verification, and encryption and decryption algorithms. The committee uses the DKG protocol to generate public and private keys between nodes, while ensuring that the committee can tolerate 1 / 2 Byzantine nodes. An attribute key verification algorithm is designed to allow users to filter out invalid keys issued by Byzantine nodes. This invention applies X-ABE to implement the Decentralized Access Control Protocol (DACCS) in cloud storage scenarios, applying X-ABE to the stages of issuing user attribute keys and encrypting session keys to achieve encrypted data transmission. Combined with a sharded blockchain architecture, intra-shard consensus is used to ensure consistency among committee nodes during key issuance. User attribute information, ciphertext hash values, and other information are recorded on the blockchain.

The utility model discloses a handrail assembly and a vehicle, and the handrail assembly comprises a handrail, a first connecting piece and a second connecting piece, the cup stand mechanism is arranged on the handrail; and the foldable table plate is rotatably connected with the handrail through a first rotating shaft so as to rotate in and out of the storage groove. Therefore, through the arrangement of the armrest assembly, on the basis that the functions of an armrest and a cup stand are reserved, the opening and closing states of the foldable table plate can be flexibly switched to provide a platform for placing articles and working for a driver and passengers, so that the multifunctionality of the armrest assembly is effectively improved, and the multi-purpose requirement of a user is met.

The present application belongs to the field of disease treatment and immunology, in particular, the present application discloses an antibody or antigen-binding fragment thereof against CD73, a nucleic acid molecule encoding the same, an immunoconjugate, a bispecific molecule and a pharmaceutical composition comprising the same, and the use thereof for enhancing an immune response and / or treating a tumor.

The utility model relates to a batch rectification device for recovering centrifugal mother liquor, which structurally comprises a batch rectification reaction kettle, a rectification tower, a condenser, an intermediate tank, a heavy phase product tank and a light phase product tank, a fourth switch valve is arranged on a pipeline between the top outlet of the rectifying tower and the inlet of the condenser, a bypass pipeline is connected between a pipeline between the fourth switch valve and the inlet of the condenser and a pipeline between the second switch valve and the outlet of the rectifying reaction kettle, and a third switch valve is arranged on the bypass pipeline; and a sixth switch valve is arranged on a branch pipeline between the outlet of the condenser and the inlet of the intermediate tank. The batch rectification device has the advantages that the control valve is additionally arranged in the batch rectification device, and each stage of batch rectification / distillation is controlled through the operation state of the valve; and an intermediate tank is additionally arranged at the top of the tower, and a system containing a free water phase or other two liquid phases is extracted through a decanted phase, so that the high-quality requirement of a product is met.

The invention provides an interaction system and method for controlling an intelligent support through a mobile phone, the interaction system is arranged on the mobile phone, the mobile phone is connected to the intelligent support, the interaction system comprises a user interface, a Bluetooth connection module, a camera connection module, a control module and a central processing unit, the central processing unit is connected to the Bluetooth connection module, the camera connection module and the control module and is used for receiving, calling, analyzing and processing various data information of the mobile phone and the intelligent support, the mobile phone is used as a main brain to control the intelligent support, and the intelligent support is controlled through a camera, a microphone, an acceleration sensor and a gyroscope of the mobile phone. Information and emotion interaction between the user and the intelligent support is achieved, operation is easy, and use is convenient.

This invention discloses a backdoor attack method, system, and medium based on multi-object semantic coexistence in text-to-image diffusion models. This method utilizes the perspective of multi-object semantic coexistence in text-to-image diffusion models to develop MOBA backdoor attack schemes. First, by constructing a trigger alignment dataset and optimizing backdoor implantation and semantic preservation in parallel, the attack success rate and visual concealment are effectively improved, reducing the impact of semantic corruption on attack effectiveness. Second, during model training, an attention-based decoupling backdoor enhancement mechanism is adopted. By decoupling the attention regions of different objects, the semantic integrity of the input prompt is maintained while the backdoor is activated and the attention distribution is reasonably adjusted to reduce the impact of generation bias on attack concealment. The method of this invention ensures both visual concealment and model performance under benign input while achieving efficient backdoor attacks.

The invention discloses a variable Qinchuan flute, which is characterized in that a conventional Qinchuan flute is improved in design, and in order to relieve the playing burden and enable a player or a learner to better perform the emotion of music, the following modifications are made on a musical instrument: a rotary copper sleeve is arranged between a first hole and a fourth hole, so that the function of the conventional flute is reserved; when music similar to Qinchuan is required to be learned and played, the positions of the holes are changed, the copper sleeves are rotated, the sizes of the two holes are changed into an ellipse with the long axis of 6.9 mm and the short axis of 5.4 mm, the positions are moved, the central points of the holes move 7.6 mm towards the direction of the first hole, and the intonation of the three holes is influenced after the two holes are shrunk and move backwards, so that under the condition that the sizes of the three holes are not changed, the four holes of the net move 2.6 mm towards the direction of the four holes, and the intonation of the three holes is influenced. And intonation and performance of each hole are ensured.

The invention relates to the technical field of cosmetics and preparations thereof, and discloses a heat-resistant liquid crystal emulsion system based on acetylated sodium hyaluronate as well as a preparation method and application thereof, the heat-resistant liquid crystal emulsion system comprises the following components in parts by weight: 1-6 parts of a liquid crystal emulsifier, 0.01-0.2 part of acetylated sodium hyaluronate, 5-60 parts of grease, 0.1-1 part of a thickening agent, 0.1-1 part of a preservative and the balance of water, totaling 100 parts. The preparation method comprises the following steps: respectively preheating the oil phase and the water phase according to the ratio, emulsifying under high-speed homogenization, and stirring and cooling at a controlled temperature. The core of the invention is that acetylated sodium hyaluronate is introduced into a liquid crystal system as a structural stabilizer, and the thermal stability of a liquid crystal structure is remarkably improved through the anchoring effect of the acetylated sodium hyaluronate and a liquid crystal layer; after the emulsion is stored at 40 DEG C for a long time, the liquid crystal texture is kept complete, and the emulsion has excellent long-acting moisturizing performance and can be used as an ideal carrier of high-end cosmetics and external medicine preparations.

This invention belongs to the field of biomedical technology, specifically relating to the application of phyllanthin (PHY) in the preparation of drugs for the treatment or prevention of colitis. The technical problem this invention aims to solve is to provide a new option for the treatment of colitis. The technical solution of this invention is the application of phyllanthin (PHY) in the preparation of drugs for the treatment or prevention of colitis, ulcerative colitis, or Crohn's disease. This invention is applicable to the treatment or prevention of colitis, providing a treatment solution with both "anti-inflammatory" and "barrier repair" functions.

The embodiment of the utility model discloses an integrated flow measuring and fire fighting device, and belongs to the technical field of metering equipment. The fire hydrant comprises a fire hydrant main body, the fire hydrant main body comprises a hydrant body, the side face of the hydrant body is provided with a water outlet and a water suction port which are buckled through a blank cap in threaded connection, the middle position of the hydrant body is provided with a valve rod penetrating into the bottom of the hydrant body, the valve rod abuts against a valve clack buckled at a valve seat, and the top of the valve rod is connected with a starting rod arranged outside the hydrant body; the monitoring main body comprises a main body pipe fitting, an elbow connecting seat is arranged on the side surface of the main body pipe fitting, a valve seat of the bolt body is mounted on the elbow connecting seat, a flow meter is arranged in the middle of the main body pipe fitting, a detection end exceeds the bottommost surface of the main body pipe fitting, the flow meter extends upwards out of the main body pipe fitting, and a data connector is arranged at the top of the flow meter. By arranging the lateral monitoring structure, the monitoring structure directly monitors the flow of the water supply pipe, and the purposes that the water volume of the water supply pipe network and the fire-fighting water flow can be monitored in real time, fire-fighting work is not affected, and the overall structure of the fire hydrant is not changed are achieved.

The utility model relates to the technical field of ultrasonic welding machines, and discloses an ultrasonic welding machine which comprises a bottom plate, an ultrasonic welding machine assembly is arranged on one side of the top of the bottom plate, a feeding assembly is arranged on the other side of the top of the bottom plate, and the feeding assembly comprises a stepping motor. The ultrasonic welding machine assembly is arranged, the welding machine body, the ultrasonic welding head and the welding base are adopted to form the ultrasonic welding machine, the normal function of the ultrasonic welding machine is guaranteed, the feeding assembly is additionally arranged, and an electric push rod is controlled to stretch to push a pressing plate to move downwards; two objects needing to be welded can be fixed and limited, the top of the positioning plate and the top of the welding base are located on the same horizontal plane, the objects can be driven to move by controlling the stepping motor to rotate forwards, the objects are moved to the welding base, the bottoms of the objects are attached to the welding base, and welding is facilitated; the stepping motor is controlled to rotate reversely to bring back the object, and the object can be taken down conveniently.

The application relates to a key control circuit, method, device, equipment, storage medium and remote controller, and relates to the technical field of electronics. The key control circuit comprises a key module, a power supply module, a control module and a power supply control module; the key module is used for simultaneously turning on a passage between the power supply module and the control module and a key code signal triggering passage when the key module is operated; the control module is used for starting timing and outputting a first control signal to the power supply control module when a power supply signal is acquired in a power-off state, the first control signal is used for controlling the power supply control module to be turned on, so that the control module is powered by the power supply module within a preset delay time length; when the key module is not operated within the preset delay time length, a second control signal is output to the power supply control module, the second control signal is used for controlling the power supply control module to be turned off, so that the control module is stopped being powered by the power supply module. The application is used for solving the problem that the power consumption of the remote controller is large in standby mode.

The utility model belongs to the technical field of laser cutting machines, and particularly relates to a waste trolley of a high-power laser cutting machine, which comprises a trolley body, and a high-aluminum ceramic refractory fiberboard, a graphite plate and a protective plate are sequentially arranged at the bottom of the trolley body upwards. According to the waste trolley, the size of the trolley is increased based on an original waste trolley, meanwhile, fire-resistant and high-temperature-resistant materials are added, and damage of laser to a waste trolley body is prevented. According to the waste trolley, the functions of an original waste trolley are reserved, and the waste trolley is convenient to assemble, push, pull and overturn. And meanwhile, some heat-resistant and heat-insulating materials are added, so that the waste trolley can work intact and normally under the working condition of high-power laser cutting parts.

The present application provides siRNA delivery nanomaterials targeting M2 macrophages, which are mannosylated bovine serum albumin nanoparticles encapsulating siRNA interfering with KLK12. The mannose coating of the materials of the present application can provide targeting effect on M2 macrophages, and the siRNA released after endocytosis of the materials can silence the expression of KLK12 and its downstream MMPs genes, reduce the degradation of collagen fibers in lung tissues, thereby controlling the number and volume of pulmonary tuberculosis granulomas, preventing the occurrence of active tuberculosis, and providing a new option for the treatment of tuberculosis.

The invention relates to a functional decellularized tissue engineering tracheal graft compounded with a cervical latissimus flap lining, and belongs to the technical field of tissue engineering and regenerative medicine. The invention provides a functional decellularized tissue engineering tracheal graft compounded with a cervical latissimus flap lining, the graft comprises a cervical latissimus flap, a banded muscle and a decellularized tracheal stent, the cervical latissimus flap lining is arranged on the decellularized tracheal stent, the subcutaneous tissue side of the cervical latissimus flap is attached to the inner wall of the decellularized tracheal stent, and the banded muscle lining is arranged on the inner wall of the decellularized tracheal stent. The banded muscle wraps the outer side of the decellularized tracheal stent. The decellularized tracheal stent used by the graft is perforated at multiple points, is lined with the latissimus latipes flap and is externally covered with the banded muscle, so that the advantages of an autologous flap tissue trachea, allograft tracheal transplantation and a tissue engineering trachea are effectively combined, the structure and the function of an original trachea can be reserved, and the graft has good biomechanical properties and growth potential and is suitable for being used in the field of medical treatment. An immunosuppressive agent does not need to be used, and revascularization and internal and external blood transportation can be quickly realized.

The invention relates to the technical field of aeronautical part manufacturing, and particularly discloses a directional solidification hollow turbine blade ceramic core head treatment method which comprises the following steps: S1, respectively measuring the thermal expansion rates of a ceramic core and a mold shell which are slowly heated from room temperature to 1550 DEG C, and calculating the amount of a gap which needs to be reserved between the mold shell and the ceramic core when the mold shell is heated to a pouring temperature; s2, a method for limiting the ceramic core in the mold shell and freely expanding / shrinking the ceramic core is given, namely, a counter bore structure is arranged on the ceramic core, the surface of the ceramic core is pre-filled with a coating and a wax sheet, and a gap between the ceramic core and the mold shell is formed; and S3, a crystal growth channel is arranged in a gap between the mold shell and the ceramic core head, and mixed crystals are prevented from being formed in the gap between the ceramic core and the mold shell. The method not only thoroughly solves the problem of disordered crystal grains of the core head at the fixed end of the directional solidification hollow blade, but also can keep the function of fixing the relative position of the ceramic core in the mold shell by the core head at the fixed end, and has a remarkable effect on improving the production qualification rate of the directional solidification hollow turbine blade.

The present application relates to the technical field of medical devices, in particular to a lumbar spondylolisthesis reduction device, comprising pedicle screws for providing fixation, the pedicle screws being detachably connected with anchor seats, further comprising a degradable ring, an elastic element and a connecting piece; the connecting piece is fixedly connected with the anchor seat, and is used for being connected on the spinous process of the lower adjacent segment of the spondylolytic vertebral body, and a reduction force is applied to the spondylolytic vertebral body by tightening the connecting piece; the elastic element is fixedly connected with the connecting piece, and the degradable ring is fixedly connected with the elastic element; the degradable ring is used for locking the tightening length of the connecting piece in an initial state, so that the connecting piece is in a fixed state; the elastic element is used for being constrained in an invariable state when the degradable ring is complete, and is released after the degradable ring degrades to a predetermined threshold, so that the connecting piece obtains an elastic displacement space. The present application is used for reserving a certain physiological activity degree between the vertebral bodies; the transition from fixation to dynamic stabilization is realized, and the reduction effect and function reservation are taken into account.

The steering wheel connecting plate comprises a first fixing plate, a second fixing plate and a supporting plate, the first fixing plate and the second fixing plate are oppositely arranged, and mounting holes are formed in the first fixing plate and the second fixing plate; the supporting plate is perpendicular to the first fixing plate and the second fixing plate, the two ends of the supporting plate are connected with the first fixing plate and the second fixing plate respectively, and a hole is formed in the supporting plate. Wherein the first fixing plate is provided with a bending part which is bent towards the inner wall of the supporting plate, the second fixing plate is also provided with a bending part which is bent towards the inner wall of the supporting plate, and the bending parts are parallel to the supporting plate. The steering wheel connecting plate is adopted, lossless rapid installation is achieved, and the function of an original directional wheel is reserved. According to the water scraper, the supporting plate is adopted, so that the types of grounds which can be matched with the water scraper are increased, meanwhile, the bending part is adopted to effectively prevent shaking, good stability is achieved, and the water absorption effect is improved.

This invention discloses a novel use of Artemisia annua seeds, a medicinal and edible compound composition for relieving hangovers and protecting the liver, chewable tablets, and their preparation process. This invention is the first to discover that the mucilage in Artemisia annua seeds slows down ethanol diffusion through a dual mechanism of physical adsorption and three-dimensional network blockage, thus slowing down the rate of ethanol absorption in the digestive tract, reducing the peak blood plasma concentration, and delaying or prolonging the time of intoxication. Therefore, it can be used in the preparation of health products / functional foods that protect the stomach, prevent intoxication, and delay alcohol absorption. Based on this discovery, this invention provides a medicinal and edible compound composition for relieving hangovers and protecting the liver, composed of 10-15 parts by weight of Pueraria lobata, 10-15 parts by weight of Hovenia dulcis, 8-10 parts by weight of Lilium brownii, 4-8 parts by weight of Poria cocos, 4-8 parts by weight of Dioscorea opposita, and 4-8 parts by weight of Artemisia annua seeds. Furthermore, to balance rapid effectiveness and compliance, it is formulated as a chewable tablet. This chewable tablet can significantly prolong the time of intoxication and shorten the sobering-up time, and is significantly superior to the group lacking Artemisia annua seeds in terms of antioxidant indicators (SOD, GSH, MDA) and hangover relief effect.

The utility model provides a charging circuit and a charging control circuit thereof, and the charging circuit comprises a first power converter, the input end of which is connected with an AC input voltage, and the output end of which outputs a first DC power supply voltage and a first DC power supply current; the first end of the second power converter is connected with the output end of the first power converter through a first switch; the battery pack is connected with the second end of the second power converter; the at least one output branch is connected with an intermediate node of the first power converter and the second power converter, and each output branch comprises an output port connected with external equipment and a second switch connected between the intermediate node and the output port; and the charging control circuit is used for controlling the charging path of the charging circuit according to the protocol parameters of the equipment connected to the at least one output port and the working state of the first power converter, so that the travel charger and the mobile power supply are combined together, and the convenience of a user is greatly improved.

Provided are an anti-CLDN18.2 antibody or antigen-binding fragment thereof, a nucleic acid molecule encoding the same, an immunoconjugate, bispecific molecule, chimeric antigen receptor and pharmaceutical composition comprising the same. The antibody or antigen-binding fragment thereof is used for preventing and / or treating a tumor. Fig. 1A Fig 1A

The utility model relates to a deck transport ship which comprises a deck, and a cargo blocking coaming is arranged on an original walking platform installation area on the deck; the walking platform is arranged on the top of the cargo blocking coaming and located on the side face close to the ship side, and the walking platform is located over the original walking platform installation area. The cargo blocking coaming is expanded to the original walking platform installation area, the walking platform is reserved and moved to the position above the original walking platform installation area and is connected with the side face, close to a ship side, of the cargo blocking coaming, unnecessary space occupation is reduced, the space occupied by a walking channel on the gunwale is reduced to the maximum extent, and therefore the cargo storage area is enlarged; by means of the design, expansion of the cargo hold area is achieved, the function of the walking platform is reserved, and the cargo transportation efficiency is improved.

The present disclosure relates to the technical field of water irrigation; specifically relates to a water scheduling system and a water scheduling method thereof; the system comprises a reservoir, has a flood discharge building and a water release tower; the water release tower is provided with a first diversion pipeline and a second diversion pipeline; a regulating reservoir is provided with a liquid inlet pipeline and a liquid outlet pipeline, and the second diversion pipeline is communicated with the liquid inlet pipeline; a plurality of irrigation systems, one irrigation system corresponding to at least one farmland; each irrigation system is communicated with the liquid outlet pipeline of the regulating reservoir; the first diversion pipeline is communicated with each irrigation system at the end far from the water release tower; the system and the method can consider flood control and irrigation, and improve the utilization rate of water.

The utility model relates to the technical field of recuperating equipment, in particular to a cervical vertebra pillow with a traditional Chinese medicine bag, which comprises an upper cervical vertebra pillow and two cervical vertebra side limiting pillows, a lower cervical vertebra pillow is fixedly arranged at the bottom of the upper cervical vertebra pillow, a semicircular neck and back groove is arranged at the bottom of the lower cervical vertebra pillow, and the two cervical vertebra side limiting pillows are respectively positioned on the left side and the right side. Latex inflation holding balls are arranged in the middle of the bottom face of the cervical vertebra side limiting pillow, traditional Chinese medicine bags are installed in the upper cervical vertebra pillow and the lower cervical vertebra pillow, and a supporting plate is arranged in the cervical vertebra side limiting pillow. According to the cervical vertebra pillow provided with the traditional Chinese medicine bag, after the heightening plate is additionally arranged in the side pillow and matched with the inflatable ball, the height and thickness of the side pillow can be adjusted, different cervical vertebra auxiliary supporting and limiting functions can be provided according to different conditions, the comfort degree in the using process can be improved through the sweat-proof pad, and meanwhile the traditional Chinese medicine bag can be placed in the medicinal material inserting bag arranged inside; and the traditional Chinese medicine bag is convenient to replace by matching with the zipper.

The invention provides a curing device for a printed circuit board after surface mounting, and particularly relates to the technical field of printed circuit board processing equipment.The curing device comprises a T-shaped machine body, a radiation curing unit is fixed in a curing box body, the radiation curing unit comprises an inner suspension body, a top cover, a lampshade body and a UV lamp body, and the UV lamp body is installed in the lampshade body; according to the printed circuit board surface-mounted post-curing device, the dynamic thermal field adjusting mechanism is independently arranged below each lampshade body, and the dynamic thermal field adjusting mechanisms are matched with the temperature detection parts corresponding to the dynamic thermal field adjusting mechanisms and the dynamic driving assemblies installed on the outer walls of the two sides of the bearing frame body; the electronic control linkage of the three parts is realized, and the adjusting mechanism performs the angle adjusting action according to the temperature measuring signal, so that the technical defects that the curing temperature of the PCB surface is not uniform and the dynamic adjustment is lacked from the radiation field level in the traditional curing device after the printed circuit board is mounted are solved, the active dynamic regulation and control of the PCB curing thermal field are realized, and the production efficiency is improved. The overall uniformity of a PCB curing thermal field is guaranteed, and the curing quality of the PCB after surface mounting is improved.

The application discloses a device for monitoring the pressure of confined water in a borehole in real time and a testing method, and belongs to the technical field of hydrogeological exploration and geotechnical engineering testing, and the technical points are as follows: the device comprises an orifice sealing cover, a pipeline shunt adapter, a mechanical pressure gauge, a control valve, a pressure-temperature integrated sensor, a data transmission assembly, a data acquisition conversion module and a data processing terminal. The orifice sealing cover is sealingly connected with a borehole orifice sleeve, the mechanical pressure gauge and the pressure-temperature integrated sensor are respectively communicated with the pipeline shunt adapter, the pressure-temperature integrated sensor is connected with the data processing terminal through the data transmission assembly and the data acquisition conversion module, and when testing, the control valve is opened, the mechanical pressure gauge and the pressure-temperature integrated sensor start reading the water pressure and temperature, the pressure and the temperature are synchronously collected as two measurement indexes, and the pressure / temperature-time change curve is displayed, stored and generated in real time.

The invention relates to the technical field of wine brewing processes, in particular to a preparation method of aroma-enhanced antioxidant wild blueberry wine, the brewing process needs multiple steps of crushing, fermentation, ageing and the like, and in order to ensure the quality of the wine, methods of low-temperature fermentation, addition of a proper amount of auxiliary materials, fermentation time control and the like are generally adopted. The process optimization measures are helpful for improving the taste and oxidation resistance of the wine. On the basis of not destroying the original white spirit and wild blueberry components, the taste of the wine is improved, the bitterness of the blueberry wine is effectively improved, the fruit fragrance of the wine is added, and the effects of protecting eyesight, resisting cancer, delaying senescence and the like of the wild blueberries are well reserved. The wild blueberry wine contains a large amount of anthocyanin, and the natural antioxidant can effectively remove free radicals in the body, slow down cell aging and delay the aging process. In addition, anthocyanin also has the effects of protecting eyesight and preventing cardiovascular diseases.

The invention discloses a melody flute which comprises a flute body, a blowing hole, a membrane hole, a sixth hole, a fifth hole, a fourth hole, a third hole, a second hole, a first hole, a fundamental tone hole, a first auxiliary hole and a second auxiliary hole are sequentially formed in the flute body, a first variable device is arranged between the fourth hole and the sixth hole, and a second variable device is arranged between the first hole and the fourth hole. The flute not only can keep the function of a conventional flute, but also can be used for playing the small-two-degree music according to needs.