The invention discloses an anti-
hemolysis hydrogel coating as well as a preparation method and application thereof, a micron-sized porous structure and a hydrophilic
silane bonding layer are constructed on the surfaces of various base materials, and the
adhesive force of the
hydrogel coating and the base materials is remarkably enhanced through a physical topology winding and
covalent bond connection method. Through the methods of spraying, dipping,
coating, mold forming and the like, the device can be suitable for blood contact
medical instruments with different shapes and materials; by adjusting the formula and preparation process parameters of the hydrogel, the special requirements of different
medical instruments can be met, and the hydrogel has wide applicability and good expandability. Through optimized materials and design, the anti-
hemolysis hydrogel coating disclosed by the invention has remarkable technical advantages in the aspects of reducing
hemolysis risk, improving
biocompatibility, simplifying the structure of
medical equipment and the like.