77 results about "Continuous crystallization" patented technology

The invention provides a dynamic cooling structure and a dynamic cooling method of a triazole continuous crystallizer, and relates to the technical field of triazole crystallization, the dynamic cooling structure comprises a cooling jacket, the cooling jacket comprises an inner attaching layer, a middle cooling liquid cavity and an outer heat preservation layer, the middle cooling liquid cavity is provided with a spiral plate, and the inner attaching layer is in contact with the crystallizer; a plurality of first thermometers are axially arranged in the crystallizer, the middle-layer cooling liquid cavity is connected with a water inlet pipe and a water outlet pipe in a penetrating mode, an electromagnetic flow valve is arranged on the water inlet pipe, a controller is arranged on the crystallizer, and the controller is electrically connected with the first thermometers and the electromagnetic flow valve. The inner attaching layer is tightly attached to the crystallizer, so that the heat conduction path is shortened; a spiral plate in the middle-layer cooling liquid cavity can guide cooling water to form ordered turbulent flow, so that the temperature dead angle of a traditional cooling cavity is reduced, and the heat exchange area and the heat exchange efficiency are greatly increased; the temperature field in the crystallizer is uniformly distributed, and the overall service life of the crystallizer is prolonged.

The application discloses a production process of electroplating grade potassium pyrophosphate, which uses potassium carbonate and diaphosphorus pentoxide as raw materials, and adds a catalyst to react in a high-pressure reaction kettle. After the reaction is completed, water is added for dissolution, and the pH value of the slurry is controlled to be 9.0-10.0. After being filtered through a precision filter, the slurry is punched into a slurry storage tank, and the slurry storage tank is maintained at 75-95 DEG C. The slurry in the storage tank is punched into an evaporation and concentration device for concentration, and then the concentrated liquid is punched into a continuous crystallization device for continuous crystallization operation. After centrifugal treatment, the filtrate is recycled into the evaporation and concentration device. The potassium pyrophosphate crystals are subjected to vacuum drying treatment in a vacuum drying equipment, and then are packaged into finished products after being crushed and sieved. The potassium pyrophosphate crystals obtained by the application have high purity, less caking phenomenon, and stable and controllable product quality.

The invention discloses a continuous crystallization method and system of copper sulfate pentahydrate and a copper sulfate pentahydrate crystal, and the method comprises the following steps: S1, tangentially adding a supersaturated solution of copper sulfate pentahydrate from the bottom of a cyclone fluidized bed crystallizer to form a rotationally rising flow field in the crystallizer; s2, adding a copper sulfate pentahydrate seed crystal to enable the seed crystal to be in a suspended and fluidized state and grow; s3, mixing the copper sulfate pentahydrate mother liquor with supplemented fresh feed liquid, treating to form a supersaturated solution of the copper sulfate pentahydrate again, and returning to the step S1 for circulation; s4, process parameters of continuous crystallization are controlled, and the ratio of the feeding flow Qm to the mother liquor circulation flow Qc is not larger than 3.56%; s5, maintaining the void ratio epsilon of the bed layer to be 0.7 or above by leading out a crystal product; according to the invention, stable and continuous operation can be realized, crystal breakage and secondary nucleation are reduced, and high-purity copper sulfate pentahydrate crystals with large particle size, uniform particle size distribution and regular morphology are obtained; the production efficiency is high and the energy consumption is low.

The utility model discloses an auger type continuous crystallization device which comprises a melting kettle, the melting kettle is provided with a stirring device, the top end of the melting kettle is provided with a material inlet and a solvent inlet, the outer wall of the melting kettle is provided with a clamping sleeve I, an inner coil pipe I is arranged in the clamping sleeve I, and a heating medium is arranged in the inner coil pipe I and communicated with a heating medium circulating device; a discharging port is formed in the bottom of the melting kettle and communicated with at least one transversely-arranged packing auger through a pump machine, a driving motor is arranged on one side of the packing auger, the power output end of the driving motor is connected with a shaft of the packing auger, blades are fixed to the shaft, a crystal mush outlet is formed in the discharging end of the packing auger, a second clamping sleeve is arranged on the outer wall of the packing auger, and a second inner coil pipe is arranged in the second clamping sleeve. And a refrigerant is arranged in the inner coil pipe II which is communicated with the refrigerant circulating device. The scheme can effectively prevent crystals from hanging on the wall and being accumulated and blocked, and improves the crystallization process efficiency.

The application provides a continuous crystallization mother liquor concentration regulation and impurity removal device and method, and belongs to the technical field of continuous crystallization equipment. A suction circulating pipe is designed outside the crystallization tank to ensure that the mother liquor fully flows in the whole continuous crystallization system, the concentration of the crystallization mother liquor is homogenized, and local supersaturation and thermal crystallization are avoided. A first inner pipe is arranged above the working liquid level in the crystallization tank to draw out the upper impurities and the accumulated light component mother liquor of the crystallization tank. In combination with the design of the open mother liquor and the impurity separation device, not only can the crystallization rate be reduced due to the too low local concentration, but also the impurities enriched at the top of the crystallization tank can be discharged, so that the influence of the impurities on the crystal quality is greatly reduced. In combination with the mother liquor parameter monitoring device arranged on the outer circulating pipe, the parameters of the crystallization mother liquor can be monitored in real time, the mother liquor extraction and circulation amount are more controllable, the crystallization environment stability is improved, and the efficient and stable generation of large particle crystals is facilitated.

The present application relates to a method for improving the grade of potassium chloride in the process of preparing potassium chloride by using a vacuum crystallizer, comprising a potassium chloride crystallization step (S1), a fine potassium mother liquor is introduced into a DTB vacuum crystallizer for crystallization, part of small particle nuclei enter the circulating channel, are dissolved and then returned to the DTB vacuum crystallizer, and a slurry containing large particle nuclei is discharged to obtain a large particle crystal slurry; a screening step (S2), the large particle crystal slurry is screened by a first screening device to obtain a first screen oversize and a first screen undersize, a second screening device is used to screen the first screen undersize to obtain a second screen oversize and a second screen undersize; a large particle size nucleus treatment step (S3), the first screen oversize is dissolved with fresh water to obtain a targeted mother liquor, and the targeted mother liquor is returned to the circulating channel and then into the DTB vacuum crystallizer for continuous crystallization; and a small particle size nucleus treatment step (S4), the second screen undersize is returned to the inside of the DTB vacuum crystallizer for continuous crystallization. The present application can improve the grade of potassium chloride.

The utility model relates to the technical field of pharmaceutical equipment, in particular to continuous crystallization temperature control equipment for tilpotide. According to the technical scheme, the temperature control device comprises a temperature control machine and further comprises a rotating groove formed in the top of the temperature control machine, and an oil filling port is formed in the inner bottom wall of the rotating groove; the refueling funnel is rotationally connected into the rotating groove; the rotating rod is fixedly connected to the outer wall of the middle of the oil filling funnel, and a rotating groove is formed in the temperature control machine. Through cooperation of the rotating groove, the oil filling port, the oil filling funnel, the rotating groove, the rebounding mechanism, the anti-reversion mechanism and other structures, the temperature controller and the oil filling funnel are integrally designed, during oil filling, an oil inlet of the oil filling funnel can be rotated to be overlapped and communicated with the oil filling port, and the funnel does not need to be additionally taken and placed; after use, the anti-reversion mechanism is opened, and the rebound mechanism automatically resets to close the funnel, so that residual oil is prevented from being exposed, the cleaning requirement is reduced, and the problems of cleaning, pollution and equipment operation risks caused by the use of additional refueling equipment are solved from the source.

A continuous phosphate crystallization system and a phosphate manufacturing method. The continuous phosphate crystallization system comprises a monoammonium phosphate production system (100), an integrated continuous crystallizer (7), a crystallization circulation pump (9), a crystallization heater (10), a crystallization vacuum condensation system (11), a crystallization material pump (12), a thickener (13), and a centrifuge (15), wherein a raw material input end of the integrated continuous crystallizer (7) is configured to be connected to a raw material phosphoric acid of a second concentration and an ammonia gas, or to be connected to a monoammonium phosphate slurry output end of the monoammonium phosphate production system (100), a circulating material output end of the integrated continuous crystallizer (7) is connected to a circulating material input end by means of the crystallization circulation pump (9) and the crystallization heater (10) in sequence, a crystallized material output end is connected to an input end of the centrifuge (15) by means of the crystallization material pump (12) and the thickener (13) in sequence, and the centrifuge (15) outputs a phosphate to be dried. The method comprises: delivering a raw material phosphoric acid of a first concentration in the range of 40-58% to the monoammonium phosphate production system (100) to obtain flash steam and a monoammonium phosphate slurry, and delivering the monoammonium phosphate slurry into the integrated continuous crystallizer (7) to obtain a crystallized material; or, delivering a raw material phosphoric acid of a second concentration in the range of 75-85% and an ammonia gas into the integrated continuous crystallizer (7) to obtain a crystallized material; and sequentially performing thickening, centrifugation and drying on the crystallized material to obtain a phosphate.

The invention provides a method for continuously crystallizing 4, 4 '-diaminodiphenylmethane. The method comprises the following steps: mixing a 4, 4 '-diaminodiphenylmethane crude product with a solvent, enabling the mixture to sequentially pass through a 1 # crystallization kettle, a 2 # crystallization kettle, a 3 # crystallization kettle, a 4 # crystallization kettle and a 5 # crystallization kettle at a set flow rate, and finally enabling the mixture to enter a centrifugal machine for solid-liquid separation to obtain the high-purity 4, 4'-diaminodiphenylmethane. The kettle-type continuous crystallization is realized, the crystallization efficiency is improved, the crystallization temperature change can be effectively controlled, the product crystal form is good, and the product purity is high.

This invention discloses an apparatus and method for detecting anomalies in a continuous crystallization process. These are corresponding solutions, in which: image analysis methods are used to extract the color information of each pixel in the crystallization image; based on the color attributes of each pixel in the image, principal component analysis is used to extract principal components; these principal components comprehensively consider the correlation between the color attributes of different pixels and can reflect the essential features of the image; based on the principal components, a multivariate statistical process control model can be constructed, thereby enabling real-time detection of the state of new continuous crystallization process images. Overall, the above-mentioned solutions provided by this invention can effectively support the automation and intelligent development of continuous crystallization process state detection.

The invention relates to the technical field of crystallization equipment, in particular to centrifugal anti-blocking gas-liquid separation continuous crystallization equipment. According to the technical scheme, the device comprises an evaporative crystallization system and a gas-liquid separation system integrated in a scrubber tank. A high-speed rotating centrifugal separation mechanism is adopted to replace a traditional wire mesh demister, efficient gas-liquid-solid separation is achieved through centrifugal force, and the problem of blockage caused by crystal attachment is fundamentally solved. The gas-liquid separation system is provided with a mechanical liquid discharge structure which can be automatically opened and closed and has a self-dredging function, and a differential adjusting mechanism which can generate a rotating speed difference to realize online scale scraping and blockage clearing. The device realizes continuous, efficient and stable purification of crystal-containing steam, effectively protects key equipment such as a compressor, ensures complete closed-loop recovery of mother liquor, has the advantages of strong anti-clogging performance, high separation efficiency, automatic operation and convenient maintenance, and is suitable for the continuous crystallization process of Bayer process mother liquor and other high-difficulty materials.

The application discloses a kind of azoxystrobin continuous crystallization method, belong to pesticide fungicide technical field.It includes the following steps: first crystallizer, second crystallizer, third crystallizer, fourth crystallizer head-to-tail sequentially interconnect, and from top to bottom are set, the crystal slurry in the crystallizer utilizes height difference self-flow discharge;First, the concentration is 25-30% mass concentration of butyl acetate solution containing azoxystrobin is carried out to crystal operation;After the crystal of butyl acetate solution containing azoxystrobin is precipitated, butyl acetate solution containing azoxystrobin is added to first crystallizer, temperature control is at 53-57 ℃ temperature, stays for a certain time;Then the crystal slurry is overflowed or pumped into second crystallizer, third crystallizer, fourth crystallizer in sequence and is cooled and crystallized, the crystal slurry in fourth crystallizer is overflowed or pumped into transfer tank or centrifuge, and the product is obtained after the crystal slurry is post-treated.The particle size uniformity of the crystalline crystal obtained by the continuous crystallization method provided by the application.

The utility model discloses a device for preparing ammonium polyvanadate by continuously crystallizing a sodium vanadate solution. The device comprises a premixing tank, a liquid storage tank, a reaction kettle and a filter press, the premixing tank is provided with a sodium vanadate solution inlet, an ammonium sulfate inlet and a sulfuric acid inlet, an outlet of the premixing tank is communicated with an inlet of the liquid storage tank, an outlet of the liquid storage tank is communicated with an inlet of the reaction kettle, and an outlet of the reaction kettle is communicated with an inlet of the filter press; the reaction kettle is provided with a heating structure and a sulfuric acid inlet. According to the device, the pre-mixing tank is independently arranged, the process in the pre-mixing tank is controlled in the use process, so that no crystal precipitate is generated in the pre-mixed vanadium liquid, and the crystallization process is performed in the reaction kettle through the transition of the liquid storage tank, so that the stability of the ammonium polyvanadate crystallization process can be improved, and the particle size of the ammonium polyvanadate can be increased to reduce the cleaning difficulty; the stability and purity of the ammonium polyvanadate in the crystallization process are improved, and meanwhile the particle size of the ammonium polyvanadate is increased.

The invention provides continuous crystallization equipment for polyaluminum chloride. The continuous crystallization equipment comprises a solution tank, the crystallization barrel is erected on the solution pool, the crystallization barrel comprises a crystallization shell, a heating shell, a first fixing plate, a sealing plate and heat preservation cotton, the heating mode of the crystallization barrel is heat transfer from inside to outside, and solution crystallization is conducted on the outer side face of the crystallization shell; the material scraping device comprises a first support fixed on the solution tank, a second fixing plate is arranged on the first support, the second fixing plate is connected with a material scraping plate, and the material scraping plate is in contact connection with the outer side surface of the crystallization shell; the crystallization conveying device comprises a spiral conveying device arranged on the side face of the solution pool, and a discharging hopper is arranged at one end of the spiral conveying device, the crystallization of the polyaluminum chloride can be achieved, and energy is saved due to the fact that a cylinder heating mode from inside to outside is adopted.

The invention belongs to the technical field of electrolyte materials, and provides a lithium hexafluorophosphate continuous crystallization process method and a process device.The process method adopts a continuous crystallization mode, the crystallization process is divided into three continuous sections, and feeding and discharging are conducted at the same time, so that a lithium hexafluorophosphate solution continuously flows through all reaction chambers; performing crystal growth in the crystal expansion reaction chamber, and stabilizing the crystal form in the aging reaction chamber; meanwhile, by controlling the flowing time of the lithium hexafluorophosphate solution in each reaction chamber, the continuously flowing lithium hexafluorophosphate solution reaches a specific reaction state in each reaction chamber, so that the obtained crystal product is large in particle, uniform in distribution, good in fluidity, few in wrapping impurities, low in acid content, low in insoluble substance content, low in metal impurity content and high in yield; and the production efficiency can be improved.

The invention relates to the technical field of continuous crystallization and purification of sodium cromoglycate, and provides continuous crystallization and purification equipment and a continuous crystallization and purification process of sodium cromoglycate, the continuous crystallization and purification equipment comprises a preheater body, a first crystallizer body, a centrifugal separator body, a cleaning machine body and a second crystallizer body which are communicated in sequence, and the continuous crystallization and purification equipment further comprises a driving motor, an assembly cylinder, an embedded plate and a stirring paddle plate. When a sodium cromoglycate solution in the crystallizer is stirred and mixed through the stirring paddle plate, the sodium cromoglycate solution can be prevented from being attached and crystallized on the surface of the stirring paddle plate by supplying heating gas into the assembly cylinder, and the sodium cromoglycate solution is heated through the stirring paddle plate, so that fine crystals in crystal slurry are completely dissolved, and only part of larger crystals are dissolved; more growth space and supersaturation degree are provided for residual crystals, and the sodium cromoglycate solution is continuously cooled and crystallized through the crystallizer, so that the average particle size of the product is increased, the crystallization effect of the crystallizer is improved, and the use is convenient.

1. The name of the design product: titanium crystal production line. 2. The use of the design product: for controlling and adjusting the size of titanium crystals, continuously crystallizing titanium alloy products, and continuously transporting titanium alloy products from the waiting crystallization area to the crystallization area to complete the crystallization process. To achieve the function of continuous crystallization. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view 1. 5. Other circumstances that need to be explained: A, B, C, D, E, F, and G are enlarged views of the main view, the left view, the right view, and the perspective view.

The present invention provides a continuous crystallization method of tris(2,4-di-tert-butylphenyl) phosphite. The method comprises: a) a melting pretreatment step, b) a crystallization step and c) a washing and drying step. The method of the present invention allows a significant reduction of solvent residual amount: at the same time increasing product purity and production efficiency, and reducing production energy consumption.

The utility model provides a kind of sodium glutamate continuous crystallization equipment, including one-effect heater, two-effect heater, three-effect heater and gas cylinder, the top of one-effect heater, two-effect heater and three-effect heater is separately installed with one-effect separation chamber, two-effect separation chamber and three-effect separation chamber, the gas cylinder is connected with one-effect heater by first gas pipe, and the one-effect heater is connected with two-effect heater by second gas pipe.The sodium glutamate continuous crystallization equipment, with solubility in one-effect heating process, some capillary crystals are dissolved, so that a part of nucleation crystal is effectively and quickly grown and uniform, continues to evaporate and concentrates in the inside of two-effect heater, and under the transmission of circulating pump, material is circulated in the inside of circulating pipe and is flashed in separation chamber, until the volume of crystal meets the requirement, in the process of continuous crystallization, sodium glutamate can be fully crystallized and grown, and sodium glutamate meeting large volume standard can be produced.

This invention relates to a continuous crystallization method for glyphosate based on spherical seed crystal regulation. The continuous crystallization method includes the following steps: (1) continuously adding an acidic aqueous solution of glyphosate to a primary crystallizer and continuously adding an alkaline solution to control the pH at 1.0-1.8 to obtain a suspension containing primary crystals; (2) continuously adding the suspension obtained in step (1) to a secondary crystallizer and continuously adding an alkaline solution to control the pH at 1.9-3.0 to obtain a suspension containing spherical seed crystals; (3) continuously adding the suspension obtained in step (2) to a tertiary crystallizer, and obtaining glyphosate crystal products through crystal growth. This invention effectively reduces the intensity of secondary nucleation by segmented coupling control of nucleation, morphology regulation and crystal growth during continuous crystallization, and obtains glyphosate crystal products with narrow particle size distribution, large average particle size and good filtration performance.

This utility model relates to the field of high-purity gallium production technology, specifically a continuous crystallization apparatus for high-purity gallium production. It includes a boat-shaped crucible with a crystallization tank and a crystal storage tank at its top. A crystallization retrieval mechanism is installed on the boat-shaped crucible, comprising a movable frame and a rotating belt. The movable frame includes a pair of parallel support plates, and several rows of retrieval rods are fixed to the outer surface of the rotating belt. This continuous crystallization apparatus for high-purity gallium production, through its flip-up crystallization retrieval mechanism, allows the retrieval rods fixed to the outer surface of the rotating belt to promptly transfer the crystallized gallium crystals from the crystallization tank to the crystal storage tank, enabling continuous retrieval of the crystallized gallium crystals. This avoids the formation of large crystal clumps due to prolonged residence in liquid gallium, facilitating subsequent gallium quality testing.

The utility model provides a kind of continuous back extraction crystallization's device, belong to hydrometallurgy extraction and crystallization technical field, including a kind of continuous back extraction crystallizer, crystallizer inside is provided with fixed flow guide barrel, adjustable flow guide barrel and crystallization barrel, for the back extraction and solution crystallization of load organic phase.The utility model is by designing a new type of organic back extraction automatic continuous crystallization device by load organic phase pipe, circulating back extraction liquid pipe, flow guide barrel, crystallization barrel, crystal collection barrel, organic phase overflow weir tank, flow partition plate etc. Component constitutes, can realize the ion of organic load high-efficiently, fast continuous direct generation as corresponding metal salt crystal, dispense with traditional evaporation crystallization procedure, greatly save steam and electric energy, with good development prospect.

This invention relates to the field of crystallization technology, specifically disclosing a continuous crystallization apparatus for the preparation of sodium 2B, comprising a tank body, a guide pipe fixedly connected to the tank body via a limiting plate, a first power component fixedly connected to the top of the tank body, a first rotating shaft rotatably connected to the first power component, the first rotating shaft being equipped with a turbine, and uniformly distributed first and second liquid guide pipes fixedly connected to the tank body, the first and second liquid guide pipes being used to transport refrigerant, and both uniformly distributed first and second liquid guide pipes being connected to an inlet pipe and a outlet pipe. This invention utilizes the method of guiding a saturated solution at a uniform speed through the refrigerant area, causing crystals to precipitate uniformly within the saturated solution. Simultaneously, the precipitated crystals flow away from the refrigerant area with the saturated solution, facilitating further crystal precipitation in subsequent saturated solutions and improving crystal precipitation efficiency.

The utility model discloses an ammonium perchlorate continuous crystallization preparation device, and relates to the technical field of ammonium perchlorate production equipment. The continuous crystallization preparation device for ammonium perchlorate comprises an ammonium perchlorate crystallizing tank, the crystallizing tank cleaning assembly comprises a second driving motor, the output end of the second driving motor extends into the ammonium perchlorate crystallizing tank and is fixedly connected with a movable frame, and the movable frame is rotationally connected with the ammonium perchlorate crystallizing tank; a movable ring is rotationally connected to the interior of the ammonium perchlorate crystallizing tank, four connecting rods and four spiral blades are fixedly connected between the movable frame and the movable ring, and filtering holes and through grooves are formed in the surface of the movable ring. By means of the structure, ammonium perchlorate crystals attached to the inner wall of the ammonium perchlorate crystallizing tank can be scraped away conveniently, the situation that ammonium perchlorate crystal residues affect the follow-up crystallizing process of an ammonium perchlorate solution is avoided, and the yield of the ammonium perchlorate crystals is increased.

This invention belongs to the field of herbicide technology and aims to solve the problems of complex preparation processes for dichloroisoxaflubenzuron, high equipment requirements, and environmental disadvantages. To this end, this invention provides a green synthetic method for preparing dichloroisoxaflubenzuron and the application of the prepared product in herbicides. The method includes reacting 5-hydroxymethylfurfural with hydroxylamine hydrochloride to generate an oxime product, followed by the direct addition of a propynic acid derivative, and cyclization under a first bifunctional catalyst and a hydrogen atmosphere to generate intermediate I; dissolving or dispersing intermediate I in a chloride-containing electrolyte and anolyzing it to generate a dichloro intermediate II; reacting dichloro intermediate II with an acrylate compound under light conditions and a catalyst in a one-pot conversion reaction to directly obtain crude dichloroisoxaflubenzuron; and finally, introducing the crude product into a continuous crystallization and separation device to obtain a high-purity dichloroisoxaflubenzuron product. This invention features a simple process, reduces equipment requirements, and is environmentally friendly.

The invention relates to the technical field of image processing, and discloses a method for processing a three-dimensional microscopic image in a stevioside crystallization process. The systematic defects of crystal identity breakage, grain number statistics distortion and insufficient tracing precision in the prior art are overcome, and triple spanning from static tracing to dynamic spectrum, from batch tracing to event positioning and from open-loop observation to closed-loop correction is realized. An explainable, verifiable and optimizable intelligent analysis means is provided for the continuous crystallization process, so that the crystal identification accuracy and the quality tracing efficiency are substantially improved, and an event-level accurate regulation and control basis is provided for process optimization.

This utility model belongs to the field of reaction vessels, specifically relating to a continuous crystallization reaction vessel for aluminum hydroxide. It includes a crystallization vessel, a heating jacket fixedly connected to the outside of the crystallization vessel, a guide cover fixedly connected to the outside of the heating jacket, a bracket fixedly connected to the upper end of the guide cover, a motor fixedly mounted in the middle of the upper end of the bracket, the motor's shaft passing through the bracket and rotatably connected to it, a discharge mechanism provided on the motor's shaft, and a discharge cylinder fixedly connected inside the crystallization vessel. The lower end of the discharge cylinder is threadedly connected to an end cap. This utility model uses a motor to drive a support shaft to rotate, which in turn causes a perforated spiral cutter to rotate, thereby conveying the crystals through a flow channel into the guide cover and out, allowing the device to continuously add reagents for crystallization.

The invention discloses a method for realizing continuous synthesis and crystallization control of HMX by a continuous flow multi-stage stirring reactor. The method comprises the following steps: preparing a mixed material I from urotropine and acetic acid, and preparing a mixed material II from fuming nitric acid and ammonium nitrate; setting the reaction temperature and the vibration frequency of the continuous flow multi-stage stirring reactor; respectively introducing the mixed material I, the mixed material II and acetic anhydride into a first-section reactor; introducing a part of the mixed material II and acetic anhydride into a second-section reactor; and introducing water into the third-section reactor. According to the invention, continuous synthesis of HMX is realized, the problem that a solid product is separated out to block a pipeline is solved, the reaction time is shortened, the highest yield of the product is 67%, and the highest liquid chromatographic purity of the product is greater than 99%; continuous crystallization and particle size control of HMX are realized, and accurate particle size control of the product can be realized by adjusting conditions of the reactor; the liquid holdup of the reaction is greatly reduced, the safety of the reaction is improved, and a foundation is laid for large-scale production.