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145 results about "Glucose production" patented technology
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When the body produces glucose from something other than carbohydrates, the process is called gluconeogenesis. Most gluconeogenesis occurs in the liver, but a small amount also takes place in the kidneys and small intestine. ... Glucose production relies on a variety of nutrients, but biotin is one of the most important for gluconeogenesis. Biotin is needed to make the enzyme that triggers the first step of gluconeogenesis in the liver.
Regulation of food intake and glucose production by modulation of long-chain fatty acyl-coa levels in the hypothalamus
Methods of reducing food intake and glucose production in a mammal, or restoring hepatic autoregulation are provided. The methods involve increasing long-chain fatty acyl-Co-A (LC-CoA) levels in the hypothalamus, or stimulating efferent fibers in the hepatic branch of the vagus nerve. Also provided are methods of increasing food intake and glucose production in a mammal. The methods involve decreasing long-chain fatty acyl-Co-A (LC-CoA) levels in the hypothalamus of the mammal.
Owner:NAT INST OF HEALTH REPRESENTED BY THE SEC OF THE DEPT OF HEALTH & HUMAN SERVICES NAT INST OF HEALTH
Crystalline glucose producing process based on whole membrane method
ActiveCN1810994AImprove qualityNo pollution in the processInvert sugar productionGlucose productionUltrafiltration
Owner:SANDA FILM SCI & TECH XIAMEN
Method for glucose production using endoglucanase core protein for improved recovery and reuse of enzyme
The present invention pertains to a method of converting cellulose to glucose by treating a pretreated lignocellulosic substrate with an enzyme mixture comprising cellulase enzyme and endoglucanase core proteins, wherein the endoglucanase core proteins are present in the enzyme mixture at an amount relative to all endoglucanases from about 35 wt. % to about 100 wt. % and wherein the endoglucanase cellulase enzymes are present in the enzyme mixture at an amount relative to the amount of CBH and EG enzymes from about 2 wt. % to about 50 wt. %. The pretreated lignocellulosic substrate is selected from the group consisting of agricultural residues, residues after starch or sugar removal, dedicated ethanol crops, forestry products, and pulp and paper products, or combinations thereof.
Owner:IOGEN ENERGY CORP
Estimation of insulin sensitivity from CGM and subcutaneous insulin delivery in type 1 diabetes
ActiveUS9486172B2Easy to implementQuality improvementHealth-index calculationDrug and medicationsGlucose utilizationGlucose production
In a method of determining insulin sensitivity in a patient, glucose level is sensed continuously. A first area under the curve representing the glucose level over time is calculated. An amount of insulin that has been administered to the patient is sensed. An estimation of insulin on board the patient is calculated based on the glucose level and the amount of insulin administered to the patient. A second area under the curve representing the insulin on board over time is calculated. Patient data indicative of at least one patient physical parameter is received. Information indicative of amount of glucose ingested by the patient during a meal is received. An insulin sensitivity output indicative of ability of insulin to stimulate glucose utilization and inhibit glucose production in the patient based on the first and second area under the curve, the patient data and the meal information is generated.
Owner:MAYO FOUND FOR MEDICAL EDUCATION & RES +1
Disposable multi-channel electrochemical immunosensor with high sensitivity
InactiveCN102053161AEasy to operateHigh detection throughputBiological testingElectronic transmissionCarbon nanotube
The invention relates to a disposable multi-channel electrochemical immunosensor with high sensitivity. A prussian blue composite, nanogold and a capture antibody are assembled layer by layer on a disposable printing electrode array to obtain a multi-channel immunosensor. Enzyme and secondary antibody in great proportion are assembled on a carbon nano tube loading gold nanoparticles and a novel glucose oxidase functional nano composite probe is designed for sandwich immunoassay. The nano composite probe is combined with the multi-channel immunosensor to realize double signal amplification and high sensitive immunodetection of protein. The prussian blue, as electronic transmission media, catalyzes and reduces hydrogen peroxide generated by glucose oxidation under the catalysis of glucose oxidase on oxygen so as to obtain current signal. The method avoids the interference of dissolved oxygen in the detection solution and deoxidization is not required in process of amperometric detection. The invention has the advantages of wide detection concentration range, good repeatability, accurate results and the like and has a certain clinical application value.
Owner:NANJING UNIV +2
System, Method and Computer Simulation Environment For In Silico Trials in Pre-Diabetes and Type 2 Diabetes
ActiveUS20120130698A1Provide informationIneffective treatmentMedical simulationMedical data miningGlucose utilizationModel dynamics
An electronic system is provided that simulates a glucose-insulin metabolic system of a T2DM or prediabetic subject, wherein the system includes a subsystem that models dynamic glucose concentration in a T2DM or prediabetic subject, including an electronic module that models endogenous glucose production (EGP(t)), or meal glucose rate of appearance (Ra(t>>, or glucose utilization (U(t)), or renal excretion of glucose (B(t)), a subsystem that models dynamic insulin concentration in said T2DM or prediabetic subject, including an electronic module that models insulin secretion (S(t)), an electronic database containing a population of virtual T2DM or prediabetic subjects, each virtual subject having a plurality of metabolic parameters, and a processing module that calculates an effect of variation of at least one metabolic parameter value on the glucose insulin metabolic system of a virtual subject by inputting the plurality of metabolic parameter values.
Owner:UNIV OF VIRGINIA ALUMNI PATENTS FOUND
Estimation of insulin sensitivity from cgm and subcutaneous insulin delivery in type 1 diabetes
ActiveUS20130211220A1Improving control therapyEasy to implementHealth-index calculationDrug and medicationsGlucose utilizationGlucose production
In a method of determining insulin sensitivity in a patient, glucose level is sensed continuously. A first area under the curve representing the glucose level over time is calculated. An amount of insulin that has been administered to the patient is sensed. An estimation of insulin on board the patient is calculated based on the glucose level and the amount of insulin administered to the patient. A second area under the curve representing the insulin on board over time is calculated. Patient data indicative of at least one patient physical parameter is received. Information indicative of amount of glucose ingested by the patient during a meal is received. An insulin sensitivity output indicative of ability of insulin to stimulate glucose utilization and inhibit glucose production in the patient based on the first and second area under the curve, the patient data and the meal information is generated.
Owner:MAYO FOUND FOR MEDICAL EDUCATION & RES +1
Horizontal continuous crystallization method adopting return current technique
InactiveCN101109021AIncrease the amount of seedHigh yieldGlucose productionGlucose productionReturn current
The invention provides a horizontal continuous crystallization applied with returning technology, which belongs to an improvement of a crystallized glucose production method. The invention adopts a plurality of horizontal crystallization pots in series to carry out continuous crystallization process. The following is the introduction of the process. Firstly starch milk is liquefied, saccharified, filtered and bleached, evaporated and concentrated to get sugar solution. Secondly the sugar solution is sent into a first horizontal pot and continuously sent to the next horizontal pot for crystallization to get crystal slurry. Most of the crystal slurry flows out from the discharging outlet of the last crystallization pot while the small part of the slurry returns into the first horizontal crystallization pot from the discharging outlet of the last one. As the seed of the first crystallization, the small part of the slurry then mixes with the sugar solution in the first horizontal crystallization pot. Changing the traditional way of simple adding crystal seed, the technical scheme uses part of crystal slurry returning into the first horizontal crystallization pot as the seed and increases the crystal seed in the horizontal crystallization pot, thereby improves the crystallized glucose output rate and quality.
Owner:SHANDONG XIWANG SUGAR
Application of needle nano-hydroxy apatite in tooth-paste
InactiveCN1751678AFix teeth wellGood anti-caries effectCosmetic preparationsToilet preparationsGlucose productionApatite
An application of the acicular hydroxyapatite nanoparticles in preparing toothpaste for repairing and strengthening tooth and preventing decayed tooth is disclosed.
Owner:JIAMUSI UNIVERSITY
Preparation method of RS5 wheat resistant starch
InactiveCN109588695APromote decompositionEasy dischargeFood thermal treatmentFood ingredient functionsGlucose productionMoisture
The invention discloses a preparation method of RS5 wheat resistant starch. The preparation method comprises the following steps: firstly performing de-branching treatment on wheat starch through pullulanase to obtain de-branched wheat starch; then compounding the de-branched wheat starch and glycerin monostearate; finally improving the content of the wheat resistant starch through heat-moisture treatment. The content of the resistant starch in wheat starch is more than 70 percent. The wheat resistant starch prepared by the preparation method disclosed by the invention has the characteristicsof being stable in property, high in safety, blood glucose production index and the like, and easily realizes the industrial production.
Owner:HEFEI UNIV OF TECH
Cells genetically modified to comprise pancreatic islet glucokinase and uses thereof
The present invention relates generally to a population of cells genetically modified to comprise pancreatic islet glucokinase and capable of producing insulin in a glucose responsive manner and uses thereof. More particularly, the present invention relates to a population of cells so genetically modified capable of producing insulin in response to physiologically relevant levels of glucose and uses thereof. The cells of the present invention are useful in a wide variety of applications, in particular in the context of therapeutic and prophylactic regimes directed to the treatment of diabetes and / or the amelioration of symptoms associated with diabetes, based on the transplantation of the cells of the present invention into mammals requiring treatment. Also facilitated is the design of in vitro based screening systems for testing the therapeutic effectiveness and / or toxicity of potential adjunctive treatment regimes.
Owner:UNIV OF TECH SYDNEY +1
Fluorescent enzyme-linked immunoassay method for detection of galectin-4
ActiveCN106248951AGood biocompatibilityExcellent photophysical propertiesBiological testingFluorescence/phosphorescenceOxygenFluorescence spectrometer
The invention relates to a fluorescent enzyme-linked immunoassay method for detection of galectin-4. According to the method, glucose oxidase on an enzyme labeled complex combined through a target substance catalyzes glucose to generate hydrogen peroxide, then a ferrous ion solution is added to generate reactive oxygen for quenching fluorescence of a gold nanocluster solution, and fluorescence change is determined by a fluorescence spectrometer for quantitative detection of a target molecule. Fluorescent gold nanoclusters used in the method have stable luminescence and are sensitive to response to the reactive oxygen, and are more stable in controllability and more convenient to operate when used as a detection probe. The detection system constructed by the method has the advantages of simple synthesis, low cost, and high sensitivity and stability, and is expected to be more widely applied and extended in clinical biomolecular detection.
Owner:FUZHOU HOSPITAL FOR INFECTIOUS DISEASE
Method for Producing Glucuronic Acid by Glucuronic Acid Fermentation
The object of the present invention is to provide a microorganism having an excellent ability to specifically oxidize the hydroxymethyl group of glucose, and a method of producing glucuronic acid and / or glucuronolactone by using such a microorganism to directly oxidize glucose, and the invention is directed at a microorganism which produces glucuronic acid directly from glucose and a mutant strain which is capable of specifically oxidizing the hydroxymethyl group of glucose and in which a DNA nucleotide sequence corresponding to 16S rRNA has the nucleotide sequence of SEQ ID NO: 1 in the sequence listing, and the invention is also directed at a method of producing glucuronic acid and / or glucuronolactone by specifically oxidizing the hydroxymethyl group of glucose using the mutant strain, and this invention enables D-glucuronic acid and / or D-glucuronolactone to be produced and furnished easily and safely at a high yield and a low cost.
Owner:ENSUIKO SUGAR REFINING
Isolation and purification of human insulin producing cells for the treatment of insulin dependent diabetes
InactiveUS20060148079A1Pancreatic cellsGenetically modified cellsHigh concentrationInsulin dependent diabetes
A method for producing an ex vivo population of human insulin-producing cells that produce insulin in response to glucose from a patient is disclosed. The population of insulin producing cells is derived from human epithelial cells by causing those epithelial cells to differentiate into insulin producing cells. In one embodiment, the epithelial cells are derived from human mesenchymal stem cells (MSCs). The MSCs can be cultured from human bone marrow. In one embodiment, a culture of epithelial cell linage is generated by cultivating a sample of human cells containing a mixed culture containing human MSCs to produce an enriched culture of MSCs having a higher concentration of MSCs than the sample; and then differentiating cells from the enriched culture into cells of the epithelial cell lineage.
Owner:PAUNESCU VIRGIL +3
Preparation method of self-energy-providing glucose inspection electrochemical sensor based on ZnxBi2S3+x sensitized NiTiO3
The invention relates to a preparation method of a self-energy-providing glucose inspection electrochemical sensor based on ZnxBi2S3+x sensitized NiTiO3. The method successfully enables ZnxBi2S3+x tobe modified in situ to NiTiO3 surface through a continuous ion layer adsorption mode, thereby making up for the problem of low utilization efficiency of NiTiO3 for visible light; and meanwhile, through a matched band-gap structure and excellent sensitization, photoelectric conversion efficiency is greatly improved, and good photoelectric response is obtained. Glucose oxidase is modified on an electrode and catalyzes glucose to be detected in an electrolyte solution to produce gluconic acid and hydrogen peroxide, wherein the latter serves as an electron donor and can be combined with photogenerated holes generated by the ZnxBi2S3+x, thereby well hindering combination of photo-induced electron-holes, further promoting transfer and transmission of photo-induced electrons and improving sensitivity of the optoelectronic signal and the prepared sensor; by catalyzing different concentrations of glucose, different degrees of photoelectric response is generated, and detection of glucose is realized; and limit of detection is 0. 35 muM.
Owner:UNIV OF JINAN
Multifunctional clostridium bifermentans and application thereof
ActiveCN107217023AMay alter metabolic pathwaysEnhanced acetate pathwayBacteriaMicroorganism based processesMetaboliteBacterial strain
The invention belongs to the technical field of microorganisms, and specifically relates to multifunctional clostridium bifermentans and application thereof in producing hydrogen through fermentation and increasing the yield of acetic acid. A bacterial strain is clostridium bifermentans EZ-1, and the preservation number is CGMCC (China General Microbiological Culture Collection Center) NO. 13913. The multifunctional clostridium bifermentans is capable of generating clean fuel hydrogen and metabolites such as acetic acid and butyric acid by utilizing glucose. Due to addition of nano magnetite and ferrihydrite in appropriate concentrations, a metabolism path of the multifunctional clostridium bifermentans can be regulated, so that the yield of the acetic acid can be increased. By microbial fuel cell detection, the situation that the bacterial strain has power generation ability is discovered, and the maximum current output density can be up to 6.3 mA / m<2>. The bacterial strain is first multifunctional novel clostridium bifermentans which is reported at present, can be applied to biological products of hydrogen, acetic acid and butyric acid generated through biomass fermentation, has power generation potential and has a wide application prospect.
Owner:YANTAI INST OF COASTAL ZONE RES CHINESE ACAD OF SCI
Method of producing high fructose corn syrup and glucose in same production line
InactiveCN109527523AIncrease liquefaction jet concentrationReduce water consumptionSugar food ingredientsSugar derivativesHigh concentrationProduction line
The invention provides a method of producing high fructose corn syrup and glucose in a same production line. A certain amount of glucose syrup is added into a mother liquor so that the mixture can meet the requirements of monosaccharide components of F42 high fructose corn syrup; the mixture is subjected to isomerization so as to convert glucose into fructose after isomerization; and then discoloring, ion exchanging, concentrating, and packaging are performed to produce F42 fructose syrup. A conventional glucose production technology is optimized, a high concentration liquefying production method is adopted; high fructose corn syrup and glucose are co-produced; the byproducts of glucose are recovered and reutilized; investment, water resources, and energy are saved, and energy saving and emission reduction are realized.
Owner:河南飞天生物科技股份有限公司
High-purity and high-polymerization-degree glucose production method
InactiveCN104844725AProcess Condition Improvement and AdjustmentEfficient removalGlucose productionIon exchange
The invention belongs to the technical field of glucose production and particularly relates to a high-purity and high-polymerization-degree glucose production method. The method comprises the steps of material mixing, polymerization, reaction ending, decoloration, membrane separation, ion exchange, concentration and spray drying. By the aid of the method, the production program is simplified greatly, material are not in contact with the outside, secondary pollution and cross pollution of human factors to finished products are prevented or reduced, the product quality is good, and the production cost is low.
Owner:SHANDONG MINQIANG BIOTECH
Systems and methods to estimate nutritional needs of human and other patients
ActiveUS8927490B2Hydroxy compound active ingredientsPeptide/protein ingredientsGlucose productionMedicine
Systems, techniques and methods for estimating the metabolic state or flux, e.g., the body energy state (“BES”) of a patient, are disclosed. The BES provides deep insight into the nutritional needs of the patient, thus allowing for a sort of exquisite glycemic control with regard to the patient. The invention discloses systems and methods for estimating fractional gluconeogenesis, which is the % of glucose production that comes from gluconeogenesis (“GNG”), as opposed to glycogenolysis (“GLY”), the other form of glucose production. Nutritional formulations, materials, cocktails and methods for feeding patients by parenteral and other means are disclosed. The amount, type and rate of such nutritional feeding are typically based upon the above estimating. The invention discloses formulations that contain labels, such as deuterium, for medical diagnostics, such as for estimating BES and fractional gluconeogenesis. The invention is suitable for any sort of patient, including those who are injured, such as with traumatic brain injury, ill, or have other conditions that stress the metabolic system.
Owner:RUN THEM SWEET
Method for improving bagasse enzymolysis efficiency through delignification pretreatment and addition of additive
PendingCN109355331AReduce manufacturing costImprove enzymatic hydrolysis efficiencyFermentationGlucose productionCellulase
The invention provides a method for improving the bagasse enzymolysis efficiency through delignification pretreatment and addition of an additive. The method comprises the steps of delignification pretreatment of a bagasse raw material, enzymolysis and the like. The air-dried and smashed bagasse raw material is mixed with a sodium hydroxide solution with a certain concentration or an acid sodium chlorite solution with a certain concentration, a reaction is conducted at the temperature of 20-180 DEG C for 0.5-12 hours for pretreatment, and pretreated residues rich in cellulose are obtained; cellulase and the additive are added into the residues for enzymolysis, so that the enzymolysis efficiency is improved. According to the method, through sodium hydroxide or sodium hypochlorite pretreatment and addition of the additive in the enzymolysis stage, the enzymolysis efficiency is improved, the enzymolysis time is shortened, the glucose production cost is reduced, and the method has a good application prospect.
Owner:SOUTH CHINA AGRI UNIV
Bacillus licheniformis high-temperature alpha-amylase mutant and application thereof
ActiveCN105802940AIncrease contentReduce contentMicroorganism based processesFermentationBacillus licheniformisNucleotide
Provided are a bacillus licheniformis high-temperature alpha-amylase mutant and application thereof.A nucleotide sequence of the high-temperature alpha-amylase mutant is shown as SEQ ID NO.1, and an amino acid sequence of the high-temperature alpha-amylase mutant is shown as SEQ ID NO.2.The mutant is obtained by conducting protein engineering improvement and selection on high-temperature alpha-amylase from bacillus licheniformis, the glucose content in a product of hydrolyzed starch can be improved and the dextrin and oligosaccharide content can be reduced by applying mutant enzyme in the hydrolyzed starch, the glucose content in syrup obtained through separate starch hydrolysis is 72%, the using amount of saccharifying enzyme in the follow-up further glucose production can be decreased, and reduction of the production costs is promoted.
Owner:GUANGXI UNIV
Method for preparing isomalto-oligosaccharide from glucose BD liquor
ActiveCN104561193ANo pollution in the processNo pollution, zero emissionsFermentationChromatographic separationGlucose production
The invention discloses a method for preparing isomalto-oligosaccharide from glucose BD liquor. The method comprises the following steps: (1) glucose BD liquor preparation,(2) decolorization and filtration, (3) ion exchange, (4) glucoside conversion, (5) enzyme deactivation, (6) filtration, (7) decolorization, (8) ion exchange and (9) steaming: a discharged material after ion exchange in the step (8) is pumped into a five-effect falling-film evaporator for evaporation and concentration until the mass percent concentration of the material is 70-75% to prepare isomalto-oligosaccharide, wherein the discharge temperature ranges from 80 DEG C to 85 DEG C. Compared with the prior art, the method has the benefits that waste liquor (BD liquor) after chromatographic separation of glucose mother liquor in a crystal glucose production process is taken as a raw material, so that local materials are used, wastes are turned into wealth, and the glucose mother liquor in the crystal glucose production process is comprehensively utilized by 100%; the effects of no pollution and zero emission are achieved; the added value of a product is increased.
Owner:河南飞天生物科技股份有限公司
Concentration evaporation method for producing glucose
The invention belongs to the technical field of glucose production, and particularly relates to a concentration evaporation method for producing glucose. The method mainly solves the technical problems of high cost, short service life and narrow concentration range of the concentration evaporation method in conventional glucose production. The invention adopts the technical scheme that: steam is conveyed to an effect I evaporator, an effect II evaporator and an effect III evaporator through outer pipes; the secondary gas generated in the effect I evaporator, the effect II evaporator and the effect III evaporator is separated from syrup through an effect I separation chamber, an effect II separation chamber and an effect III separation chamber; and the separated secondary gas is sequentially compressed in two turbine compression fans and heated to form secondary steam, and the secondary steam is recycled in the effect I, II and III evaporators and provides heat for the effect I, II and III evaporators. The method has the advantages of low evaporation concentration cost, long service life and wide concentration range.
Owner:长治市金泽生物工程有限公司
Wastewater treatment method in starch glucose production
InactiveCN103304110AEasy to handleEfficient removalWater/sewage treatment by centrifugal separationMultistage water/sewage treatmentTreatment effectOxygen
Owner:NORTH CHINA PHARMA KANGXIN
Method for reclaiming and utilizing saccharified residue from production of glucose
InactiveCN1879496ASolve the source of pollutionFood processingAnimal feeding stuffGlucose productionFiltration
Owner:SHANDONG XIWANG SUGAR
Recombinant microorganism having ability to produce [lactate-co-glycolate] copolymer from glucose, and method for preparing [lactate-co-glycolate] copolymer using same
There is provided a recombinant microorganism having producibility of poly(lactate-co-glycolate) from glucose, and more particularly, a recombinant microorganism having producibility of poly(lactate-co-glycolate) without adding an exogenous glycolate precursor, and a method of preparing [poly(preparing lactate-co-glycolate)] using the same. According to the present invention, the poly(lactate-co-glycolate) in which the concentration of the glycolate fraction is high may be prepared at a high concentration without supplying exogenous glyoxylate. Therefore, the present invention may be effectively used for treatment.
![Recombinant microorganism having ability to produce [lactate-co-glycolate] copolymer from glucose, and method for preparing [lactate-co-glycolate] copolymer using same](https://images-eureka.patsnap.com/patent_img/7ed3ae65-9542-4b1b-a76f-bac290887279/US20140030775A1-20140130-D00001.png "Recombinant microorganism having ability to produce [lactate-co-glycolate] copolymer from glucose, and method for preparing [lactate-co-glycolate] copolymer using same")
![Recombinant microorganism having ability to produce [lactate-co-glycolate] copolymer from glucose, and method for preparing [lactate-co-glycolate] copolymer using same](https://images-eureka.patsnap.com/patent_img/7ed3ae65-9542-4b1b-a76f-bac290887279/US20140030775A1-20140130-D00002.png "Recombinant microorganism having ability to produce [lactate-co-glycolate] copolymer from glucose, and method for preparing [lactate-co-glycolate] copolymer using same")
![Recombinant microorganism having ability to produce [lactate-co-glycolate] copolymer from glucose, and method for preparing [lactate-co-glycolate] copolymer using same](https://images-eureka.patsnap.com/patent_img/7ed3ae65-9542-4b1b-a76f-bac290887279/US20140030775A1-20140130-D00003.png "Recombinant microorganism having ability to produce [lactate-co-glycolate] copolymer from glucose, and method for preparing [lactate-co-glycolate] copolymer using same")
Owner:KOREA ADVANCED INST OF SCI & TECH +1
Method of preparing cytidine disodium triphosphate and application
The invention relates to a manufacturing method of disodium cytidine triphosphate, which comprises the following steps: proceeding enzymatic conversation with CMP material; proceeding ion exchange column chromatography; separating and purifying. The enzymatic conversation reaction principle is that: brewers' yeast gets the needed enzyme liquid of the enzymatic conversation reaction; brewers' yeast produces a plurality of biological enzyme as sugar glycolysis enzyme and phosphorylase with high sugar glycolysis ability; the biological energy produced by glycolysis glucose with sugar glycolysis enzyme is transferred to cytidine monophosphate by ATP; cytidine monophosphate and phosphate radical combines to form cytidine triphosphate with the effect of phosphorylase. The method shapes low cost, simple operation, high production, high product purity by optimization, which comprises the following steps: getting enzyme liquid; proceeding enzymatic conversation by adding the main material cytidine monophosphate, monobasic potassium phosphate of proper quantity and glucose; getting product by deposition, ion exchange column chromatography, segregation, purification, refining and vacuum drying.
Owner:BEIJING SL PHARMA
Saccharizing process in glucose production
The saccharizing process for glucose production includes the following steps: setting crystallized glucose mother liquid or the mixture of crystallized glucose mother liquid and starch emulsion into saccharifying tank; and saccharifying via adding enzyme of 0.4-0.5 L / T at pH 4.2-4.5 and 60-62 deg.c for 40-60 hr. The process has raised crystallized glucose mother liquid utilizing rate, disaccharide, trisaccharide and other oligosaccharides converted into glucose, DE value up to 91-96 %, raised glucose yield and low production cost.
Owner:SHANDONG XIWANG SUGAR
Glucose production process for reducing steam consumption
InactiveCN101748220ASolve the problem of high usageReduce dosageGlucose productionGlucose productionIon exchange
The invention relates to a glucose production process, in particular to a glucose production process for reducing steam consumption. The invention aims at providing the glucose production process which fully utilizes the material temperature difference of the glucose processes to exchange material heat for reducing the steam consumption and saving energy and reducing comsumption. The technical scheme of the invention is as follows: the glucose production process for reducing steam consumption comprises: decoloration, ion exchange, and evaporation procedure; a heat exchanging system is arranged before decoloration, and through the heat exchanging system, the steam condensate is used for heating glucose solution. The benefits of the invention are as follows: the problem of high steam consumption in the current glucose production procedure is solved. The steam consumption for producing per ton of finished product of glucose is reduced by 0.28 t, and the production cost is reduced by 29.4 RMB.
Owner:XIWANG GROUP
A preparing method of a tumor catalytic nanometer reactor based on graphene quantum dots and application of the reactor
ActiveCN108998014AIncrease lethalityNon-toxicMaterial nanotechnologyCarbon active ingredientsAbnormal tissue growthBiocompatibility Testing
A preparing method of a tumor catalytic nanometer reactor based on graphene quantum dots and application of the reactor are disclosed. The method includes (1) preparing graphene quantum dots (Py-GQDs)having peroxidase activity; and (2) activating, with carbodiimide / N-hydroxysuccinimide, carboxyl ends of the Py-GQDs prepared in the step (1) at room temperatures, and covalently linking the Py-GQDsprepared in the step (1) o amino ends of glucose oxidase (Gox) through amidation to prepare the tumor catalytic nanometer reactor PyG-Gox. The reactor is advantageous in that the prepared reactor, ina tumor slightly acid environment, firstly degrades glucose in the environment to generate a large amount of hydrogen peroxide and further degrades the hydrogen peroxide into hydroxyl free radicals, thus generating obvious killing effects for tumor cells, and therefore, the reactor can be applied for preparing antitumor medicines. In addition, the reactor is extremely low in catalytic efficiency in neutral conditions so that the reactor shows extremely good biocompatibility and does not poison normal tissues.
Owner:WENZHOU MEDICAL UNIV
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