41 results about "Glucuronolactone" patented technology

Esterifying and crystallizing process for preparing glucuronolactone is carried out by oxidizing by starch acid, hydrolyzing, one-stage concentration dewatering for oxidized starch hydrolysate, two-stage dewatering for one-stage concentrate, adding two-stage concentrate into acetic acid to esterify at 65~70 degrees C, distilling to remove weak acid, third-stage dewatering, lowering temperature, crystallizing by dynamic gradient at 25+-5 degrees C, 1~2 degrees C / hr speed ratio and <=40hrs, filtering to obtain crude product. It is cheap, has less consumption, shorter crystallizing time and more output.

The object of the present invention is to provide a microorganism having an excellent ability to specifically oxidize the hydroxymethyl group of glucose, and a method of producing glucuronic acid and / or glucuronolactone by using such a microorganism to directly oxidize glucose, and the invention is directed at a microorganism which produces glucuronic acid directly from glucose and a mutant strain which is capable of specifically oxidizing the hydroxymethyl group of glucose and in which a DNA nucleotide sequence corresponding to 16S rRNA has the nucleotide sequence of SEQ ID NO: 1 in the sequence listing, and the invention is also directed at a method of producing glucuronic acid and / or glucuronolactone by specifically oxidizing the hydroxymethyl group of glucose using the mutant strain, and this invention enables D-glucuronic acid and / or D-glucuronolactone to be produced and furnished easily and safely at a high yield and a low cost.

The invention discloses a beverage with a function of quick physical energy recovery and a method for preparing the beverage with the function of quick physical energy recovery.The beverage is mainly prepared from taurine, inositol, L-tyrosine, AAKG, potassium salt, magnesium salt, citrulline malate, guarana extract, glucuronolactone, maltodextrin, D-ribose, citric acid, potassium sorbate, flavoring agents and the balance purified water.The method includes: dissolving sweeteners into an appropriate amount of purified water and filtering; adding the taurine, the inositol, the L-tyrosine, the AAKG, the potassium salt, the magnesium salt, the citrulline malate, the guarana extract, the glucuronolactone and the like into purified water, dissolving completely, and filtering; well mixing the two solutions, adding the citric acid, the potassium sorbate and the flavoring agents, well mixing, and performing high-temperature sterilization and filling to obtain finished products.The beverage with the function of quick physical energy recovery is capable of not only regulating body fluid equilibrium and improving exercise tolerance but also enhancing anti-fatigue ability and promoting fatigue recovery after exercises.

The invention discloses a solid beverage containing N(2)-L-alanyl-L-glutamine, which is prepared from the following raw materials: N(2)-L-alanyl-L-glutamine, sucrose, taurine, arginine aspartate, lysine hydrochloride, ornithine hydrochloride, vitamin B3, vitamin B6, vitamin C, vitamin B12, sodium citrate, glucuronolactone, potassium chloride, DHA (docosahexaenoic acid) and sweetening agent. The solid beverage can supplement energy, enhance vigor and resist senility and fatigue, is composed of amino acids, vitamins, additives, microelements and the like, and is a functional beverage preparation for regulating the human functions; and the solid beverage is suitable for travel enthusiasts, athletes, manual workers and brain workers to drink.

The invention belongs to the field of Chinese medicinal preparations for livestock, and specifically relates to a Chinese medicinal compound preparation for protecting liver and removing mildew and a preparation method of the Chinese medicinal compound preparation. The Chinese medicinal compound preparation comprises 10-20 parts of pseudo-ginseng, 10-20 parts of schisandra, 10-15 parts of silybum marianum, 10-20 parts of licorice, 10-15 parts of red-rooted salvia root, 20-30 parts of yeast cell wall, 5-10 parts of vitamin C and 2-5 parts of glucuronolactone. The Chinese medicinal compound preparation can be used for cleaning toxin inside the livestock while removing mildew, and can also improve the immunity of the body so as to strengthen the disease resistance; and all components are safe and non-residual, so the effect is significant.

The invention provides a normal temperature crystallization method of glucuronolactone. The method comprises the following steps: adding an glacial acetic acid and an acetic oxide to obtain a reactant after carrying out enzymolysis and fermentation on oxidized starch; firstly, agitating the reactant at the rotating speed of 30-100 r / min at room temperature, and then agitating the reactant at a constant speed for 8-12 hours; continuing to agitate at the constant speed of 50-80 r / min for 48-52 hours, and then stewing for 4-6 hours; carrying out vacuum filtration after stewing, so as to obtain a glucuronolactone crude product; washing the glucuronolactone crude product by using absolute ethyl alcohol, and then drying into constant weight. The defects that equipment in freezing crystallization is high in investment, high in energy consumption, and difficult to separate crystal are avoided by normal temperature agitating crystallization. By adopting the normal temperature agitating crystallization method provided by the invention, (1) undercooled melt is not needed again, so that an energy source consumed for producing the undercooled melt is saved; (2) soluble or insoluble impurities in the glucuronolactone are fully utilized, so that formation and growth of glucuronolactone crystal are facilitated by taking the soluble or insoluble impurities as crystal nucleus.

The invention discloses a high performance fiberboard. The prepared board has superior bending property and impact property, and is better in mechanical properties. By reasonably compounding camphor wood powder, birch wood powder and maple wood powder, the fiberboard is enabled to be uniform in size and density and better in harmony; the wood powder is subjected to modification treatment by using glucuronolactone, acetaminophen and polyvinyl alcohol, so that the fiberboard is enabled to contain multiple active groups, the gluing effect between the fiberboard and an adhesive component is facilitated; furthermore; furthermore, the compatibility of the fiberboard with modified basalt fibers is promoted, so that the mechanical properties of the board are improved; diatomaceous earth and tapioca flour are used for modifying basalt fibers, and a porous interface is formed on the surface of basalt, so that the interaction between the basalt fibers and wood fibers as well as between the basalt fibers and an adhesive is promoted, and a framework effect is achieved; therefore, the bending strength and impact toughness of the board are remarkably improved.

The invention relates to a method for cleaning and producing glucuronolactone, which comprises the steps: firstly, corn starch and water are mixed to prepare corn starch milk to be adjusted, stirred and heated up, and then the mixture is added with an evocating agent and dripped with an oxidizer to react for obtaining oxidized starch; the oxidized starch is mixed with water to prepare emulsion, pH value is adjusted to control the temperature for pasting, and alpha-amylase is added to complete liquefaction; the temperature of reaction liquid is quickly lowered and is added with maltogenic amylase for heat preservation reaction and filtration, and undissolved substance is filtered out to obtain hydrolyzate which is decompressed and distilled, so that concentrated hydrolyzate is obtained; the concentrated hydrolyzate is added with a small quantity of glacial acetic acid and acetic anhydride for the reaction of lactonization for 1h and then is added with absolute ethyl alcohol, glucurolactone which is separated out is filtered, washed and dried, and the finished products are obtained. By adopting the method for producing the glucuronolactone, the productive rate is improved by 2%; as no materials which can cause pollution is used in the course of production, and no substance that forms pollution exists, so that the pollution problem in the process of producing the traditional glucuronolactone is solved fundamentally, thus reducing the production cost.

An effervescent tablet of glucuronolactone for protecting liver contains glucuronolactone, pharmacologically acceptable acid-base pairs, additive, adhesive, lubricant, sweetening agent and flavouring. Its preparing process is also disclosed.

The object of the present invention is to provide a microorganism having an excellent ability to specifically oxidize the hydroxymethyl group of glucose, and a method of producing glucuronic acid and / or glucuronolactone by using such a microorganism to directly oxidize glucose, and the invention is directed at a microorganism which produces glucuronic acid directly from glucose and a mutant strain which is capable of specifically oxidizing the hydroxymethyl group of glucose and in which a DNA nucleotide sequence corresponding to 16S rRNA has the nucleotide sequence of SEQ ID NO: 1 in the sequence listing, and the invention is also directed at a method of producing glucuronic acid and / or glucuronolactone by specifically oxidizing the hydroxymethyl group of glucose using the mutant strain, and this invention enables D-glucuronic acid and / or D-glucuronolactone to be produced and furnished easily and safely at a high yield and a low cost.

The invention discloses a western medicine composition for treating liver cirrhosis, and the western medicine composition comprises the following main raw materials by weight: 20-35 parts of ademetionine, 35-45 parts of glucuronolactone, 4-8 parts of harmol, 17-22 parts of vasicinone, 4-9 parts of notoginsenoside R2, 1-4 parts of baicalein-7-methyl ether, 1-4 parts of Bavachinin A, 7-13 parts of Lucidin, 8-15 parts of oryzanol and 2-6 parts of amitriptyline. The raw materials of the western medicine composition for treating liver cirrhosis are strictly selected according to the understanding of the mechanism of the liver cirrhosis, the purpose of comprehensive rehabilitation can be achieved, and the western medicine composition has the characteristics of quick in effect, stable in effect, convenient to use and carry, and no toxic and side effects after long-term use.

The invention relates to a premix for reducing diarrhea of lactating piglets and a preparation method and application of the premix. The premix is mainly prepared from, by mass, 5-15 parts of potassium sulfate, 25-70 parts of zeolite, 5-15 parts of beneficial microorganisms, 5-10 parts of selenium yeast, 10-20 parts of glucuronolactone and 5-15 parts of arginine. The preparation method comprises the step that all the raw materials are mixed and stirred. The premix is simple in raw material, the intestinal health of sows is remarkably improved, the detoxification function of the liver is improved, and toxins are discharged out of the body more quickly, so that the influence of the toxins in sow bodies on the health of the lactating piglets is reduced, diarrhea of the piglets is reduced, and the health condition and growth performance of animals are improved.

The invention discloses a preparation technology of glucuronolactone, and belongs to the field of medicine raw material production. According to the preparation technology, acid pickling and water washing are mainly carried out on oxidized starch to remove impurities in the oxidized starch, the liquification and saccharification of the oxidized starch are faciliated, glycuronic acid, glucose, disaccharide and trisaccharide are obtained after the saccharification of the oxidized starch; by virtue of the property that glycuronic acid is easy to dissolve in ethyl alcohol (alcohol), but the glucose, disaccharide and trisaccharide are insoluble in alcohol, the glycuronic acid is subjected to separation and purification, so that the fermentation and impurity-removal technology is eliminated, and the production period is shortened by 72 h. The technology is simple in operation, short in reaction time, and low in requirements for equipment; the glucuronolactone prepared by the technology is high in yield and high in purity.

The invention discloses a dairy product and a preparation method thereof. In the preparation method, glucuronolactone is adopted as a fermentation agent. By adopting the method to prepare the dairy product, the problem that products in different batches are nonuniform in quality due to the fact that strain activity is instable in the process of fermentation can be solved, and the problem that theproducts are too high in viscosity due to the fact that strain fermentation is adopted can be avoided, so that low-viscosity drinking yogurt is prepared.

An object of the invention is to provide a method capable of producing D-glucuronic acid and D-glucuronolactone easily and safely in high yield and at low cost. The invention provides a method for producing glucuronic acid and / or glucuronolactone characterized by oxidizing sucrose to form sucrose carboxylic acid (and a salt thereof) (glucuronyl-fructoside, ss-D-fructosyl-(2-1)-a-D-glucuronic acid and a salt thereof), adding yeast or the like thereto to hydrolyze and assimilate the fructose moiety of the sucrose carboxylic acid (and the salt thereof) and collecting produced glucuronic acid and / or glucuronolactone.

The invention discloses a formula milk powder for reducing neonatal jaundice. The formula milk powder comprises the following components in parts by weight: 8 parts of whey protein powder, 60 parts ofglucose syrup, 18 parts of mixed vegetable oil, 1 part of medium chain triglyceride, 0.1 part of DHA algal oil, 0.1 part of arochidonic acid oil, 2 parts of albumen peptide, 0.1 part of glucuronolactone, 0.2 part of multivitamin, and 0.5 part of complex mineral. The invention further discloses a preparation method of the formula milk powder. The formula milk powder can promote metabolism of bilirubin in newborns, provides nutrition support for jaundice period of infants, relieves the jaundice symptom, and helps remission of jaundice.

Compositions comprising:saligenin or derivatives thereof or Salix ssp extracts containing from 10 to 50% of saligenin;substantially pure andrographolide or andrographolide enriched Andrographis paniculata extract containing from 5 to 30% of andrographolide;optionally N-acetyl-glucosamine and / orglucuronic acid or glucuronolactone.

The invention relates to the technical field of food biological fermentation, and particularly relates to a method for producing pumpkin sauce by fermentation technique. The method includes steps of filling fermentation liquor containing lactobacillus pentosus to a pumpkin cavity by an injector to perform the fermentation treatment before picking the pumpkin; after picking off the pumpkin, attaching a layer of bentonite slurry on the surface of the pumpkin and then curing by microwave; mixing the cured pumpkin and obtaining the pumpkin paste; adding glucuronolactone to the pumpkin paste; drying by vacuum microwave. The pumpkin sauce produced by the process is in the form of transparent colloid, the color is golden and attractive; the stability is extremely good; after coating on bread or biscuit, the softening and deliquescent phenomenon of the breast and biscuit cannot be appeared for water seepage.

The invention provides a low-fish-meal compound feed for turbots. The compound feed is prepared from 12.5-24.5% of Peru steam fish meal, 35-50% of soy protein concentrate, 2.5-4% of enzymolysis fish meal, 1.0-2.0% of mussel meat, 1.0-2.0% of scallop brims, 12-25% of high gluten flour, 0.5-1.0% of soya bean lecithin, 4.5-10% of fish oil, 4.5-10% of soya-bean oil, 0.7-2.1% of taurine, 0.2-0.6% of L-carnitine, 0.1-0.2% of a non-starch polysaccharide enzyme, 0.05-0.15% of phytase, 0.05-0.15% of glucuronolactone, 2.5-3.3% of a compound amino acid mixture, 0.5-1.0% of monocalcium phosphate, 0.1-0.2% of multivitamins for sea fishes and 0.4-0.8% of compound minerals for sea fishes. Compared to a common compound feed for turbots, the feed cost can be more effectively lowered, so that the economical cost of turbot cultivation is lowered. Moreover, the pollution on the water body caused by nitrogen and phosphorus discharge is remarkably reduced.

The invention relates to the field of high polymer materials, in particular to a low-temperature-resistant pneumatic hammer tube which comprises a PVC inner layer and a PVC outer layer, and the PVC outer layer is prepared from, by weight, HG-2500 type PVC; a tackifying resin; a first plasticizer; DOS cold-resistant plasticizer; glucuronolactone; a first stabilizer; a wear-resistant agent; a first lubricant. The invention discloses a production process of the low-temperature-resistant pneumatic hammer tube. The production process comprises the following steps: S1, preparing the PVC inner layer; S2, winding a network cable; S3, preparing a tackifying layer; S4, preparation of the PVC outer layer; S5, piercing. Gluconolactone and DOS cold-resistant plasticizer are compounded for use, so that the cold resistance of the PVC inner layer is remarkably improved, the PVC inner layer is not prone to embrittlement and cracking at low temperature, meanwhile, the low-temperature toughness of the PVC inner layer is improved, and workers can conveniently install the PVC inner layer at low temperature.

The invention discloses a postpartum antiphlogostic and edema-eliminating pharmaceutical composition for gynaecology and obstetrics. The postpartum antiphlogistic and edema-eliminating pharmaceutical composition is prepared from, by weight parts, ailanthus altissima swingle, citrus aurantium, hydrocotyle vulgaris, rhizoma acori graminei, leonurus, euphorbia kansui, abelmoschus manihot, mussaenda philippica Richard, semen lepidii, herba centellae, eclipta alba, tithonia diversifolia, oxygraphis glacialis, helwingia himalaica, clematis root, creeping mallotus root leaf, poria, elsholtzia ciliata hyland, cogongrass rhizome, angelica sinensis, dendrobium nobile, cuttlebone, maltose, glucuronolactone, alpha-pinene, linolenic acid, vitamin C, vitamin D, vitamin E, pantothenic acid, citric acid and cellulose. The postpartum antiphlogistic and edema-eliminating pharmaceutical composition combines clinical experience according to the traditional Chinese medicine, the compatibility of selected medicinal materials is reasonable, the ratio is appropriate, and various components are complementary to each other to collectively achieve the effects of clearing heat and removing toxicity, eliminating stasis and subduing swelling, promoting blood circulation to arrest pain, tonifying qi and restoring vital energy, fighting bacterium and diminishing inflammation, removing liver heat, invigorating spleen-stomach and replenishing qi and soothing the liver and regulating qi.

The invention relates to a protein adsorption-resistant capillary column. The capillary inner wall is modified with a number of protein adsorption-resistant covalently bonded coatings. The protein adsorption-resistant covalently bonded coating is formed through a photo-curing cross-linking reaction of photosensitive diazoresin and glucuronolactone under UV light irradiation. Each protein adsorption-resistant covalently bonded coating has thickness of 1.1-1.8 nm. The coating can be prepared in a water phase through a self-assembling method. The preparation process is simple and fast. The chemical bonding of the coating is realized through the photo-curing cross-linking reaction of photosensitive diazoresin and glucuronolactone so that the quality problem such as capillary blocking is reduced. The preparation method is simple and environmentally friendly and realizes high production efficiency and a low production cost. The protein adsorption-resistant capillary electrophoresis covalently bonded coated column has good quality.

The invention relates to a preparation method of ethyl glucuronide and ethyl sulfate of ethyl alcohol non-oxidative metabolite, and belongs to the field of compound preparation. According to the preparation method, glucuronolactone is used as a basic reaction raw material, the ethyl glucuronide of the ethyl alcohol non-oxidative metabolite can be obtained by reacting under ultrasonic, water bath heating and other conditions through a triacetyl bromide glucuronic acid methyl ester intermediate, and the preparation method has the advantages of low environmental factors, simple operation and easyrealization; and in addition, absolute ethyl alcohol and sulfuric acid are used as raw materials, and the ethyl sulfate of the ethyl alcohol non-oxidative metabolite is obtained through heating, filtration, precipitation, water bath evaporating and other operations, and the preparation method has the advantages of wide source of raw materials, low requirements for environmental factors, simple operation and easy realization.

The invention discloses a medicine composition for treating bartholinitis and a preparation method thereof, and relates to the technical field of medicaments of the obstetrics and gynecology department. The medicine composition for treating bartholinitis is prepared from lettuce seeds, machilus grifsii Hance, colla carapacis trionycis, roots and leaves of affined conehead, rhizomes of sorghumpro pinquum (Kunth) Hitehc., lip-fern, roots of long pepper, wood of largeleaf dogwood, herba rubiae yunnanensis, helwingia japonica (Thunb.) Dietr., roots of Szechwan-Yunnan sanicle, semen nigellae, dendrobe, lemons, maltose, glucuronolactone, an amino acid mixture, alpha-pinene, biotin, niacin, mineral matter and an antibacterial agent. The medicine composition is prepared according to the theory of traditional Chinese medicine in combination with clinical experience, the selected medicinal materials are reasonable in compatibility and appropriate in proportion, all the ingredients supplement one another and jointly achieve the effects of clearing away heat and toxic materials, dispersing stasis and diminishing swelling, promoting blood circulation and alleviating pain, tonifying Qi and reinforcing deficiency, resisting bacteria and diminishing inflammation, clearing away liver heat, tonifying middle-Jiao and Qi and tonifying the stomach and promoting fluid, and the medicine composition can effectively treat bartholinitis and thoroughly remove the disease and is significant in treatment effect, not likely to cause medicine resistance and small in side effect.

The invention provides a polypropylene plastic mold for a concrete member. The polypropylene plastic mold is prepared from the following raw materials in parts by weight: 50 to 100 parts of polypropylene injection molding grade material, 5 to 30 parts of compatilizer, 10 to 30 parts of flexibilizer, 5 to 15 parts of beta-crystal form nucleating agent, 20 to 40 parts of antioxidant and 10 to 40 parts of basalt fiber, 5-10 parts of a diatomite composite oil-based modified material is also added; the invention relates to a diatomite composite oil-based modified material, wherein a modified solution comprises hexamethylsiloxane, an acetone solvent, glucuronolactone and polyethylene glycol. The toughening agent and the fiber are added into the polypropylene, so that the toughness and rigidity of a polypropylene mold can be improved, the impact strength and the tensile strength are higher, the basalt fiber has the effect of preventing thermal degradation, the heat resistance of the mold is improved, the mold is not easy to damage and deform, and the mold is more durable, and a certain amount of auxiliaries are selected in the formula components, so that the production cost is reduced. The stability of the polypropylene resin can be improved, and a certain effect on demolding of a mold is also achieved.

The invention discloses a method for preparing 1,2-O-isopropylidene-alpha-D-glucofuranuronic acid-3-lactone. The method comprises the following steps: successively completing glucose mono-propyliden protection; catalytically oxidizing platinum carbon into mono-propyliden glucuronic acid; extracting, concentrating and lactonizing by using an organic solvent A; gradually cooling and crystallizing in an organic solvent B, thus obtaining the 1,2-O-isopropylidene-alpha-D-glucofuranuronic acid-3-lactone. The 1,2-O-isopropylidene-alpha-D-glucofuranuronic acid-3-lactone disclosed by the invention is prepared by adopting a one-pot method, the technological steps are simple, an intermediate is not required to be purified, the operation is convenient, solvents are few, and the yield is high.

The invention provides a method for preparing glucuronolactone by using a glycyrrhetinic acid fermentation waste liquid. The method comprises the following steps: inoculating a strain culture containing highly active beta-glucuronidase into a fermentation culture medium containing glycyrrhetate, fermenting to obtain a glycyrrhetinic acid precipitate, carrying out ion exchange resin recovery on glucuronic acid in the obtained fermentation liquid, and lactonizing to prepare glucuronolactone. The method mainly has the advantages of realization of the comprehensive utilization of fermentated glycyrrhizic acid, obtaining of glycyrrhetinic acid and the byproduct glucuronolactone, low energy consumption, no use of strong oxidants polluting the environment, simple steps, no byproducts, omitting of a decolorization process, and good product quality.