573 results about "Adjunctive treatment" patented technology

The invention provides an expectoration auxiliary control method and device. The method comprises the steps that audio signals of breathing sounds and cough sounds at multiple positions of the chest of a patient are collected through an audio sensor array, and a standardized audio feature data set is obtained through noise reduction, segmentation and feature extraction; a dynamic weighted graph model is constructed, and a random edge sampling algorithm and a parallel batch processing dynamic algorithm are combined to analyze and obtain a sputum viscosity index and a sputum distribution position map; based on the result, mapping the vibration parameter space into an unweighted disk diagram, and obtaining a personalized vibration treatment scheme by using a shortest path algorithm; in combination with the real-time breathing cycle of the patient, working parameters of the sound wave vibrator and the negative pressure suction device are synchronously controlled, and a coordinated and consistent multi-mode treatment execution instruction is obtained; and collecting real-time feedback data in treatment, and dynamically adjusting working parameters through reinforcement learning to obtain an optimized expectoration adjuvant therapy scheme. Intelligent adjustment can be achieved based on the real-time breathing state and sputum characteristics of the patient, the expectoration efficiency is improved, and discomfort of the patient is reduced.

The invention discloses injectable hydrogel for photo-thermal adjuvant therapy of periodontitis and a preparation method, and belongs to the technical field of high polymer material preparation, the preparation method comprises the following steps: reacting MXene dispersion liquid with epigallocatechin gallate and MgSO4; then sequentially carrying out ultrasonic treatment, centrifugation, washing and freeze-drying to obtain a multifunctional nanosheet MP-Mg; adding the multifunctional nanosheet MP-Mg into an oxidized gellan gum aqueous solution, and carrying out a mixed reaction to obtain a solution A; mixing the quaternary ammonium salt chitosan aqueous solution and the carboxymethyl chitosan aqueous solution in equal volume, and reacting to obtain a solution B; and mixing the solution A and the solution B in equal volume for reaction. The hydrogel prepared by the preparation method disclosed by the invention has injectability, photo-thermal responsiveness, biological membrane penetrability, synergistic antibacterial property and long-acting anti-inflammatory property, and an innovative and practical photo-thermal adjuvant therapy platform is provided for clinical treatment of periodontitis.

The invention discloses a system and method for performing cranial nerve stimulation based on olfaction, hearing and synchronous magnetomotive stimulation, and the system comprises a magnetic therapy bearing main body which is a magnetic therapy helmet, serves as a basic bearing structure of the system, and is used for installing all functional assemblies, providing magnetic therapy physical auxiliary stimulation, and achieving the cooperation of magnetic therapy and multi-mode stimulation; the olfactory stimulation subsystem is used for providing olfactory stimulation with precise regulation and control; the auditory stimulation subsystem is used for providing personalized audio stimulation; the magnetomotive stimulation subsystem is used for providing magnetomotive stimulation; the nerve stimulation cooperation subsystem is used for planning multi-mode stimulation as a whole and achieving regulation and control. Through the synergistic effect of olfactory stimulation, auditory stimulation and magnetomotive stimulation, three major neural pathways of olfactory, auditory and somatosensory can be activated at the same time, multi-dimensional nerve resonance is formed, the brain wave synchronization degree is remarkably improved, and the adjuvant therapy effect on Alzheimer's disease, cognitive impairment and other diseases is superior to that of single-mode stimulation.

The invention provides a micro-catheter shaping method and system for adjuvant therapy of aneurysm and related equipment, and relates to the technical field of image processing, and the micro-catheter shaping method for adjuvant therapy of aneurysm comprises the steps: obtaining an aneurysm to be treated and an image corresponding to a blood vessel where the aneurysm is located; according to the image, performing overall modeling on the aneurysm and a blood vessel where the aneurysm is located to obtain a corresponding global model, the global model including an aneurysm model and a blood vessel model; according to the global model, first key parameters corresponding to the aneurysm model and second key parameters corresponding to the blood vessel model are obtained, the micro catheter is shaped based on the first key parameters and the second key parameters, physical laws and the shaping form of the head end of the aneurysm can be considered, it can be guaranteed that the head end of the micro catheter is fed into the aneurysm, and the shaping accuracy is improved. And the in-place rate and the stability of the operation are improved.

The invention belongs to the technical field of biological medicines, and relates to application of Ackermann muciniphile or its external vesicles in preparation of a drug for treating schistosomiasis. The anti-infection immunity of a host is enhanced by adjusting intestinal flora balance (recovering diversity and composition) and improving immune response (adjusting macrophage, CD8 + T cell recruitment and Th1 / Th2 balance); meanwhile, the intestinal barrier function is improved, and pathogen invasion and inflammation are reduced; hepatic granuloma and hepatic fibrosis caused by schistosome infection are obviously relieved, and the liver function is improved; the key effect of the MIF gene in immunoregulation is disclosed, and a new direction is provided for schistosomiasis immunotherapy. Besides, the probiotics are high in treatment safety and free of obvious side effects, can be combined with chemotherapy to enhance the curative effect and reduce the side effects and drug resistance of chemical drugs, provides a lasting and comprehensive adjuvant therapy scheme for the schistosomiasis, and has important clinical application potential.

The invention belongs to the field of nano-medicine and traditional Chinese medicine, and particularly discloses an antioxidant nano-material based on self-assembly of traditional Chinese medicine and copper ions and a preparation method thereof.The nano-material is prepared from BPCu nano-particles formed by self-assembly of berberine and procyanidine B2 under induction of the copper ions, the BPCu nano-particles are further subjected to surface modification through polyvinylpyrrolidone, and the antioxidant nano-material is prepared. And the stably dispersed PVP-coated BPCu nano structure is obtained. The material is small in particle size, uniform in distribution, good in water solubility and storage stability, excellent in free radical scavenging capacity and catalase-like activity and suitable for adjuvant therapy of oxidative stress related diseases, and the preparation method is easy and convenient to operate, does not need an organic solvent and has good industrialization and disease treatment potential.

1. The name of this design product: Handheld red light therapy device for pain. 2. Purpose of this design product: This design product is used for auxiliary treatment of soft tissue injuries and chronic pain. 3. The key point of the design of this product lies in its shape. 4. The picture or photo that best illustrates the design points: Stereoscopic drawing 1.

The invention belongs to the technical field of microorganisms, and particularly relates to application of bifidobacterium longum in improving immunity and preparing products for preventing, treating and / or assisting in treating rhinitis. The preservation number of the bifidobacterium longum is GDMCC No: 65969, and the bifidobacterium longum can reduce the levels of MDA and NO in serum of mice and improve the activity of SOD and CAT and the content of GSH so as to relieve oxidative stress injury; inflammatory cell infiltration of nasal mucosa is reduced, and lung tissue inflammatory mediator level and inflammation-related gene expression are reduced to inhibit inflammation; th1 / Th2 immune balance is regulated, Th2 type cytokines are reduced, Th1 type cytokines are increased, and the high-dosage effect is close to that of loratadine. The strain has a treatment effect on allergic rhinitis through multiple mechanisms, and a new choice is provided for treatment of the strain.

The invention relates to the technical field of medical instruments, in particular to a multi-mode biological feedback ear vagus nerve self-adaptive stimulation device and method.The device comprises a host, a stimulation electrode, a signal collection bracelet and an electroencephalogram collection module, and the host comprises core hardware configuration and a power management system; the signal acquisition bracelet comprises an ECG module, a PPG module, a GSR module, a six-axis acceleration sensor and the like. The ear vagus nerve stimulation parameter can be dynamically adjusted through real-time analysis of multi-mode data such as electrocardio, electroencephalogram, heart rate variability, respiration-heart rate synchronism and emotional state, personalized precise treatment is achieved, meanwhile, the wearing comfort and the durability of the device are improved, and the application range is wide. The traditional Chinese medicine composition can be used for auxiliary treatment of various diseases such as inflammatory bowel disease, epilepsy, chronic insomnia, depression, chronic pain, anxiety disorder, post-traumatic stress disorder and autonomic nerve dysfunction, and the functions of a nervous system are adjusted and the symptoms of a patient are improved by accurately stimulating the vagus nerve in the auricular concha area.

The invention relates to application of bifidobacterium animalis in preparation of a product for preventing, treating or adjunctively treating pneumonia, and belongs to the technical field of microorganisms. The invention aims to solve the technical problem that the existing treatment of acute lung injury (ALI) / acute respiratory distress syndrome (ARDS) is mainly based on supportive means and lacks special-effect treatment drugs. According to the key point of the technical scheme, a new strain, namely the Bifidobacterium animalis ORG01 is provided, the preservation number is GDMCC NO: 67122, and the strain has good technical effects in the aspects of improving the acute lung injury effect, the strain stability, the product application convenience and the like. According to an experimental test, the bifidobacterium animalis ORG01 disclosed by the invention can be used for remarkably recovering the lung organ index of an LPS-induced acute lung injury model mouse, the TNF-alpha content in serum and the mRNA expression level of IL-6 in lung tissues to normal levels.

The invention provides a kidney cancer recurrence risk prediction method based on a deep learning model, and relates to the technical field of deep learning, and the method comprises the steps: collecting an image data set for kidney cancer high recurrence risk prediction; carrying out registration on the collected multi-stage enhanced CT image; constructing and training a kidney tumor automatic detection and segmentation model; carrying out ROI positioning cutting and quality control; and constructing a deep learning model for renal cancer recurrence risk prediction based on the multi-modal convolutional neural network, and realizing renal cancer recurrence risk prediction through the constructed prediction network model. According to the method, the multi-phase enhanced CT image of the kidney cancer patient is analyzed through the deep learning model, the tumor postoperative recurrence risk is predicted, an objective basis is provided for a clinician to make an individualized follow-up visit scheme and an auxiliary treatment decision, and excessive treatment of a low-risk patient and insufficient treatment of a high-risk patient are avoided.

The invention relates to the technical field of dental intelligent adjuvant therapy, and discloses an adjuvant therapy system and method for difficult-to-inverse suppurative periapical periodontitis, and the system comprises a multi-modal image fusion module which fuses CT / OCT images to generate a three-dimensional diagram, segments an infected region through a lightweight CNN, and outputs a probability diagram; the reinforcement learning debridement navigation module is used for optimizing the dentin injury risk by combining a biological membrane thickness dynamic planning path on the basis of a DDPG algorithm; the intelligent medicine control module is used for positioning a catheter according to an infection map, triggering medicine release by a pH / enzyme sensor and adjusting delivery pressure by PID; the biosensor monitoring module is used for detecting inflammatory factors, predicting the recurrence risk through LSTM, and triggering image rescanning and path updating when a threshold value is exceeded. Through multi-modal image fusion, reinforcement learning dynamic debridement navigation, microenvironment response type drug control and time sequence prediction closed-loop feedback, accurate elimination and relapse active inhibition of periapical periodontitis focuses are realized.

The invention relates to a dynamic intelligent fixing device for lower limb rehabilitation, which belongs to the technical field of medical instruments and comprises a dynamically adjustable leg supporting structure, a self-adaptive foot fixing device, a multi-modal stimulation system, a double-shaft linkage movement mechanism and an intelligent regulation and control system. The dynamic adjusting structure and the self-adaptive fixing device can adapt to different leg circumferences, foot types and joint motion ranges, and comfortable fixing and standard movement of a patient are guaranteed; the multi-mode stimulation system is combined with mechanical movement, pneumatic massage and myoelectricity stimulation to synergistically promote blood circulation of the lower limbs; the intelligent regulation and control system collects multi-dimensional physiological data in real time and dynamically optimizes motion parameters and stimulation intensity. The device solves the problems that an existing device is poor in adaptability, single in stimulation, lagged in regulation and control and the like, individualized precise adjuvant therapy is achieved, the lower limb rehabilitation effect and clinical benefits of postoperative lower limb fixation and VTE prevention are effectively improved, and meanwhile the operation complexity of medical staff is reduced.

The invention provides a radix asparagi homogeneous acidic polysaccharide. The radix asparagi homogeneous acidic polysaccharide contains pectic polysaccharide which is shown as a formula 1, takes rhamnogalacturonidan I (RG-I) as a core and has a homopolygalacturonic acid (HG) structural domain. The invention further provides a preparation method and application of the radix asparagi homogeneous acidic polysaccharide. The asparagi pectin polysaccharide with a new structure is found for the first time, and the asparagi pectin polysaccharide has the effect on acute lung injury. The acidic polysaccharide disclosed by the invention has the advantage of anti-ALI activity, realizes synergistic protection of intestine-lung double target regions, has anti-inflammatory and anti-oxidation double activities, is natural in source and high in biological safety, and is suitable for long-term adjuvant therapy of acute lung injury.

The invention relates to the technical field of medical instruments, in particular to a constipation adjuvant therapy appliance and a using method thereof.The constipation adjuvant therapy appliance comprises an insertion tube, a vibration sleeve is arranged at the inner end of the insertion tube, and a vibration motor is arranged in the vibration sleeve; the outer end of the insertion pipe is connected with a medium pipeline used for inputting or outputting a medium into or out of a pipe cavity of the insertion pipe. A plurality of protruding blocks are arranged on the pipe wall of the outer side of the insertion pipe. Through mechanical pressure generated by expansion of the insertion tube and the adjusting cavity of the insertion tube and local stimulation of the outer side protruding block on the rectum wall, low-frequency vibration of the vibration motor in the vibration sleeve is combined, a rectum wall mechanical receptor and a nerve conduction path are cooperatively activated in a multi-mode mode, defecation reflex is triggered, and therefore targeted intervention on defecation reflex disorder of a constipation patient is achieved. The defect that a traditional therapy does not touch a neural mechanism is overcome, and a comprehensive solution from physiological reflex activation to mechanical power enhancement is provided for constipation treatment.

The invention discloses a composite combined preparation for synergistically treating and conditioning diabetes, relates to the technical field of foods, health foods or dietary supplements for adjuvant therapy and health care of diabetes, and in particular relates to a composite combined preparation for synergistically treating and conditioning diabetes. The preparation comprises albumin peptide, saussurea involucrata culture, vitamin B1, vitamin B2, wheat oligopeptide, corn oligopeptide, collagen peptide, mulberry leaf extract, rhizoma polygonati extract, sea-buckthorn extract, isomaltitol, maltodextrin, ginseng extract and bitter gourd extract. Through the synergistic effect of all the components, comprehensive auxiliary conditioning on diabetes is realized from multiple targets of maintaining colloid osmotic pressure and nutrition, regulating glycolipid metabolism in multiple ways, protecting pancreatic beta cell functions, enhancing insulin sensitivity, preventing nerve and blood vessel complications, meeting special diet requirements and the like. The composition can be prepared into food, health-care food or dietary supplement and other dosage forms.

The invention discloses application of a combination of probiotics GOLDGUT-M520 and GOLDGUT-LR99 in preparation of a product for relieving depression, and belongs to the technical field of biological medicines. The probiotics disclosed by the invention can be used for relieving depressive symptoms, improving related symptoms, assisting in treating depression and preventing depression, and also can be used as a nutritional supplement to help maintain the balance of intestinal microflora and promote intestinal health.

A distributed healthcare network system stores intervention, context, and communication rules in databases, defining responses to patient-related events. Context includes factual circumstances tied to the patient. The system constructs a distributed ledger for each patient, incorporating their profile, therapeutic events, and context indicators based on predefined rules. Interventions are selected according to patient context and communicated to relevant network nodes, with records added to the ledger. AI models trained on patient data help identify subtle scenarios from context indicators and suggest alternative actions. Intervention rules rely on fixed thresholds and AI-driven analysis to determine appropriate responses. The ledger, distributed across the network, ensures transparency, enhances communication among patients, providers, and payers, and streamlines healthcare transactions. This method enables efficient decision-making, ensures accurate documentation, and improves healthcare coordination by maintaining an immutable, accessible record of patient interactions, interventions, and contextual factors.

1. Name of the product in this design: Percutaneous endoscopic discectomy. 2. Purpose of this design: This design is used for observation, diagnosis and adjunctive treatment of spinal parts such as intervertebral foramina and intervertebral discs. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: a 3D model.

The invention relates to a plasma lipid isomer biomarker for predicting survival benefit of neoadjuvant therapy of breast cancer and application of the plasma lipid isomer biomarker. The plasma lipid isomer biomarker is PC 17: 1 (n-8) 18: 1 (n-7), PC 18: 018: 1 (n-7), PC 14: 018: 1 (n-10), PE 16: 018: 1 (n-7), PE 14: 018: 1 (n-7) and PC 16: 1 (n-7) 18: 1 (n-9). The invention also constructs a breast cancer NAT survival benefit prediction model. According to the method, the survival benefit probability of the patient can be accurately evaluated, and a scientific basis for personalized treatment decision is provided for clinic, so that a more accurate treatment scheme is realized, the treatment effect of the patient is optimized, and excessive treatment or insufficient treatment is avoided.

This invention discloses a grape seed protein peptide with ACE inhibitory activity and its preparation method, belonging to the field of comprehensive utilization of wine fermentation by-products. This invention provides a grape seed protein peptide with ACE inhibitory activity, wherein the grape seed protein peptide is FFYPL, SGMFPFP, or WFFPGPR. The grape seed protein peptide of this invention can be used in pharmaceuticals; it has broad application prospects in the pharmaceutical field as a preventive or adjunctive treatment for patients with hypertension, or those with obesity, cardiovascular and cerebrovascular diseases, and other chronic metabolic disorders.

The application belongs to the technical field of medicine or cosmetics, and particularly relates to a composition for treating atopic dermatitis and application thereof. The composition is composed of polysaccharide of Arnebia euchroma and naphthoquinone of Arnebia euchroma, and the mass ratio of the polysaccharide of Arnebia euchroma to the naphthoquinone of Arnebia euchroma is 250-500:1. The polysaccharide of Arnebia euchroma and the naphthoquinone of Arnebia euchroma are compounded according to a specific ratio, and the two components have a synergistic effect, can significantly inhibit secretion of inflammatory factors, and promote expression of key proteins of a skin barrier, so that atopic dermatitis is treated from two paths of 'anti-inflammation' and 'barrier repair', and the effect is significantly better than that of a single component. The composition of the application is derived from natural plant ingredients, has high safety, can be prepared into various dosage forms, is used for auxiliary treatment or daily care of atopic dermatitis, and has a good application prospect.

1. The name of the design product: ultrasonic therapeutic instrument. 2. The use of the design product: for the auxiliary treatment of cardiovascular and cerebrovascular diseases, soft tissue contusion, and nervous system disease rehabilitation. 3. The design points of the design product: the combination of shape and pattern. 4. The picture or photo that best indicates the design points: perspective view 1.

The utility model relates to the technical field of eye treatment, and discloses a medicine applying device for eye treatment, which comprises a medicine applying instrument, a massage device and a medicine applying device, the medicine applying instrument comprises a machine shell, the front ends of the outer walls of the two sides of the machine shell are fixedly connected with adjusting bandages, the massage device is arranged in the machine shell, the massage device comprises a sliding cavity, and the sliding cavity is communicated with the machine shell. A sliding cavity is formed in the center in the machine shell, a motor box is fixedly connected to the inner bottom face of the sliding cavity, a servo motor is fixedly connected to the inner bottom face of the motor box, the output end of the servo motor penetrates through the motor box and is fixedly connected with an eccentric cam, and a plurality of reset springs are fixedly connected to the inner wall of the rear end of the sliding cavity. A medicine applying device is arranged in the middle of the upper surface of the machine shell and comprises a joint block, and a liquid injection opening is formed in the middle of the upper surface of the machine shell. According to the utility model, during medicine application, personalized auxiliary treatment of massage and hot compress can be provided according to specific treatment requirements of different patients, so that the treatment effect is improved.

The invention belongs to the field of traditional Chinese medicine biological medicine, and particularly relates to a medicinal and edible traditional Chinese medicine composition and a preparation method, a traditional Chinese medicine preparation and application thereof. The invention provides a medicinal and edible traditional Chinese medicine composition which comprises the following components in parts by weight: ginseng, lily, Chinese yam, angelica sinensis, poria cocos, pericarpium citri reticulatae, ginkgo, radix polygonati officinalis, rhizoma zingiberis and honey-fried licorice root. The preparation method comprises the following steps: mixing the raw materials, adding water for soaking, extracting with water, filtering an extracting solution, concentrating filtrate, and collecting paste to obtain a semi-solid extract or a liquid extract; and further drying the obtained semi-solid extract or liquid extract to obtain the solid extract of the traditional Chinese medicine composition. The traditional Chinese medicine composition provided by the invention adopts an all-medicine-food homologous formula, has no toxic or side effect, is suitable for being taken by various people for a long time, has definite functionality, and is creatively compatible aiming at chronic respiratory system diseases, especially chronic obstructive pulmonary disease in a stable phase complex pathogenesis; the traditional Chinese medicine composition can be applied to health-care products for adjuvant therapy of chronic obstructive pulmonary disease or drugs for treatment of chronic obstructive pulmonary disease.

The utility model relates to finger flexor tendon rehabilitation auxiliary equipment, and relates to the technical field of rehabilitation. The finger flexor tendon rehabilitation auxiliary apparatus comprises a seat body and a fingerstall assembly. A sliding groove is formed in the base body. The fingerstall assembly comprises a sliding piece and a belt body, and the sliding piece is slidably installed in the sliding groove; two limiting pieces are arranged on the face, away from the sliding groove, of the sliding piece in a spaced mode. The belt body sequentially penetrates through the two limiting pieces, a cavity is formed between the two limiting pieces, and the belt body and the limiting pieces can be relatively fixed. When the finger flexor tendon rehabilitation auxiliary equipment is used, training can be carried out according to different positions of different fingers of a patient, the limiting and fixing of the equipment on the fingers in the training process are reliable, and the position fixing is accurate. A therapist does not need to carry out auxiliary treatment on a patient, the work intensity of the therapist is reduced, and the risk that the therapist suffers from related hand occupational diseases is also reduced.

1. Name of the product in this design: Microneedle Ear Patch. 2. Application of this design: In the field of medical and nursing devices, it is mainly used in hospitals, clinics, traditional Chinese medicine clinics and home care scenarios for ear acupoint application, ear acupoint stimulation and daily health care, which can meet the needs of clinical auxiliary treatment, rehabilitation care and health management. 3. The key design features of this product are the combination of shape and pattern. 4. The image or photograph that best illustrates the design's key points: a 3D model. 5. This design is for a thin product; other views are omitted.

The invention provides a pulmonary nodule targeting food and medicine homologous composition based on metabonomics screening and application thereof. By analyzing a pulmonary nodule specific metabolic profile, active components, namely platycodin D, mogroside V, oyster active peptide and fermented cordycepin, which can cooperatively regulate and control an arachidonic acid inflammation pathway, a glutathione antioxidant pathway and a tricarboxylic acid cycle energy pathway are reversely screened out. Animal experiments prove that the composition can reduce the volume of pulmonary nodules by 58.3%, human body application shows that the nodules of 76.7% of subjects are reduced, and liver and kidney toxicity is avoided. The composition can be prepared into tablets, capsules and other dosage forms, can be used as functional food or adjuvant therapy drugs for high risk groups of pulmonary nodules, and realizes accurate nutrition intervention.

The invention discloses an intelligent high-precision weighing device for dietary therapy food materials of diabetics and gestational patients, which can provide balanced and reasonable structured diet recipes for the diabetics and gestational patients in a high-standard manner and accurately provide high-precision evaluation levels for various food materials. An accurate analysis data basis is provided for subsequent related therapy or nutriology research; the food materials eaten by the diabetes mellitus and gestational patients can be guaranteed to be sound in structure and balanced in multi-dimensional information with high precision; comprehensive recipes which can be adopted by the diabetes mellitus and gestational patients and are different in height, weight and other information can be output; replaceable similar food materials can be provided according to different types; according to the high-precision food material weighing device, diabetes mellitus and gestational patients can be prevented from eating improper and even taboo food materials, the accurate weight of each type of food materials can be known and determined, recipes can be intelligently changed according to blood sugar changes and disease development, complications can be prevented, and treatment can be assisted.

The application discloses a compression hemostat, and relates to the technical field of medical devices, and the compression hemostat comprises a pressing device, a fixing part and a temperature adjusting module, the pressing device comprises a pressing part and an adjusting mechanism for adjusting the contact pressure of the pressing part, the pressing device is installed on the fixing part, the fixing part is used for being fixed on a patient, so that the pressing device is kept fixed with the patient's limbs when the pressing device works, and the temperature adjusting module is used for adjusting the temperature of the pressing part, and the temperature adjusting module comprises a display screen used for displaying at least one kind of information in temperature, pressure and bleeding state, through the adjustment of the temperature of the pressing part, the patient can upgrade passive hemostasis to active auxiliary treatment according to the sensitivity and feeling of cold and heat.