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756 results about "Adjunctive treatment" patented technology

The purpose of adjunctive therapy, often called complementary therapy, is to increase the benefits of the initial treatment of a disorder by prescribing additional medications and/or treatments. Several examples of disorders and diseases that are generally treated with adjunctive therapy include cancer,...

Auxiliary expectoration control method and device

The invention provides an expectoration auxiliary control method and device. The method comprises the steps that audio signals of breathing sounds and cough sounds at multiple positions of the chest of a patient are collected through an audio sensor array, and a standardized audio feature data set is obtained through noise reduction, segmentation and feature extraction; a dynamic weighted graph model is constructed, and a random edge sampling algorithm and a parallel batch processing dynamic algorithm are combined to analyze and obtain a sputum viscosity index and a sputum distribution position map; based on the result, mapping the vibration parameter space into an unweighted disk diagram, and obtaining a personalized vibration treatment scheme by using a shortest path algorithm; in combination with the real-time breathing cycle of the patient, working parameters of the sound wave vibrator and the negative pressure suction device are synchronously controlled, and a coordinated and consistent multi-mode treatment execution instruction is obtained; and collecting real-time feedback data in treatment, and dynamically adjusting working parameters through reinforcement learning to obtain an optimized expectoration adjuvant therapy scheme. Intelligent adjustment can be achieved based on the real-time breathing state and sputum characteristics of the patient, the expectoration efficiency is improved, and discomfort of the patient is reduced.
Owner:THE FIRST AFFILIATED HOSPITAL ZHEJIANG UNIV COLLEGE OF MEDICINE

Injectable hydrogel for photo-thermal adjuvant therapy of periodontitis and preparation method of injectable hydrogel

The invention discloses injectable hydrogel for photo-thermal adjuvant therapy of periodontitis and a preparation method, and belongs to the technical field of high polymer material preparation, the preparation method comprises the following steps: reacting MXene dispersion liquid with epigallocatechin gallate and MgSO4; then sequentially carrying out ultrasonic treatment, centrifugation, washing and freeze-drying to obtain a multifunctional nanosheet MP-Mg; adding the multifunctional nanosheet MP-Mg into an oxidized gellan gum aqueous solution, and carrying out a mixed reaction to obtain a solution A; mixing the quaternary ammonium salt chitosan aqueous solution and the carboxymethyl chitosan aqueous solution in equal volume, and reacting to obtain a solution B; and mixing the solution A and the solution B in equal volume for reaction. The hydrogel prepared by the preparation method disclosed by the invention has injectability, photo-thermal responsiveness, biological membrane penetrability, synergistic antibacterial property and long-acting anti-inflammatory property, and an innovative and practical photo-thermal adjuvant therapy platform is provided for clinical treatment of periodontitis.
Owner:JILIN UNIVERSITY

Virtual reality training system and method for fireman stress disorder adjuvant therapy

The invention provides a virtual reality training system and method for fireman stress disorder adjuvant therapy, the fireman training system and method based on virtual reality are provided by utilizing the development of the virtual reality technology and the heart rate variability monitoring technology, the virtual reality environment is selected and adjusted in combination with multiple dimensions, and the fireman stress disorder adjuvant therapy effect is improved. On one hand, the fire-fighting task processing capability of the firefighter can be trained, and on the other hand, the post-traumatic stress disorder of the firefighter can be treated in an auxiliary manner, so that the firefighter is helped to overcome the fear of trauma and high pressure in the fire-fighting task, and the post-traumatic stress disorder is prevented and treated in an auxiliary manner; the cure rate of the stress disorder of the group of firemen is effectively improved, and the prevalence rate of the stress disorder is reduced. Moreover, according to the scheme, through multi-level personalized adjustment, it is ensured that the adjuvant therapy training scheme better meets the unique requirements of each fireman according to individual characteristics, individual differences, psychological states and physiological states, and the training effect is effectively improved.
Owner:HANGZHOU XINJING TECH CO LTD

System and method for performing cranial nerve stimulation based on olfactory, auditory and synchronous magnetomotive stimulation

The invention discloses a system and method for performing cranial nerve stimulation based on olfaction, hearing and synchronous magnetomotive stimulation, and the system comprises a magnetic therapy bearing main body which is a magnetic therapy helmet, serves as a basic bearing structure of the system, and is used for installing all functional assemblies, providing magnetic therapy physical auxiliary stimulation, and achieving the cooperation of magnetic therapy and multi-mode stimulation; the olfactory stimulation subsystem is used for providing olfactory stimulation with precise regulation and control; the auditory stimulation subsystem is used for providing personalized audio stimulation; the magnetomotive stimulation subsystem is used for providing magnetomotive stimulation; the nerve stimulation cooperation subsystem is used for planning multi-mode stimulation as a whole and achieving regulation and control. Through the synergistic effect of olfactory stimulation, auditory stimulation and magnetomotive stimulation, three major neural pathways of olfactory, auditory and somatosensory can be activated at the same time, multi-dimensional nerve resonance is formed, the brain wave synchronization degree is remarkably improved, and the adjuvant therapy effect on Alzheimer's disease, cognitive impairment and other diseases is superior to that of single-mode stimulation.
Owner:RONGCHEN (HEFEI) BIOTECHNOLOGY CO LTD

Microcatheter shaping methods, systems and related devices for adjuvant treatment of aneurysms

The invention provides a micro-catheter shaping method and system for adjuvant therapy of aneurysm and related equipment, and relates to the technical field of image processing, and the micro-catheter shaping method for adjuvant therapy of aneurysm comprises the steps: obtaining an aneurysm to be treated and an image corresponding to a blood vessel where the aneurysm is located; according to the image, performing overall modeling on the aneurysm and a blood vessel where the aneurysm is located to obtain a corresponding global model, the global model including an aneurysm model and a blood vessel model; according to the global model, first key parameters corresponding to the aneurysm model and second key parameters corresponding to the blood vessel model are obtained, the micro catheter is shaped based on the first key parameters and the second key parameters, physical laws and the shaping form of the head end of the aneurysm can be considered, it can be guaranteed that the head end of the micro catheter is fed into the aneurysm, and the shaping accuracy is improved. And the in-place rate and the stability of the operation are improved.
Owner:UNION STRONG (BEIJING) TECH CO LTD

Application of ackermann muciniphile or external vesicles thereof in preparation of drugs for treating schistosomiasis

The invention belongs to the technical field of biological medicines, and relates to application of Ackermann muciniphile or its external vesicles in preparation of a drug for treating schistosomiasis. The anti-infection immunity of a host is enhanced by adjusting intestinal flora balance (recovering diversity and composition) and improving immune response (adjusting macrophage, CD8 + T cell recruitment and Th1 / Th2 balance); meanwhile, the intestinal barrier function is improved, and pathogen invasion and inflammation are reduced; hepatic granuloma and hepatic fibrosis caused by schistosome infection are obviously relieved, and the liver function is improved; the key effect of the MIF gene in immunoregulation is disclosed, and a new direction is provided for schistosomiasis immunotherapy. Besides, the probiotics are high in treatment safety and free of obvious side effects, can be combined with chemotherapy to enhance the curative effect and reduce the side effects and drug resistance of chemical drugs, provides a lasting and comprehensive adjuvant therapy scheme for the schistosomiasis, and has important clinical application potential.
Owner:HUBEI UNIV OF MEDICINE

Anti-oxidation nano material based on self-assembly of traditional Chinese medicine and copper ions and preparation method of anti-oxidation nano material

The invention belongs to the field of nano-medicine and traditional Chinese medicine, and particularly discloses an antioxidant nano-material based on self-assembly of traditional Chinese medicine and copper ions and a preparation method thereof.The nano-material is prepared from BPCu nano-particles formed by self-assembly of berberine and procyanidine B2 under induction of the copper ions, the BPCu nano-particles are further subjected to surface modification through polyvinylpyrrolidone, and the antioxidant nano-material is prepared. And the stably dispersed PVP-coated BPCu nano structure is obtained. The material is small in particle size, uniform in distribution, good in water solubility and storage stability, excellent in free radical scavenging capacity and catalase-like activity and suitable for adjuvant therapy of oxidative stress related diseases, and the preparation method is easy and convenient to operate, does not need an organic solvent and has good industrialization and disease treatment potential.
Owner:LULIANG PEOPLES HOSPITAL (LÜLIANG HOSPITAL AFFILIATED TO SHANXI MEDICAL UNIV ELEVENTH CLINICAL COLLEGE OF SHANXI MEDICAL UNIV)

Hemodialysis fatigue patient-oriented health monitoring and propaganda treatment system

The embodiment of the invention provides a hemodialysis fatigue patient-oriented health monitoring and propaganda treatment system, which comprises a cloud server and a first communication device, the patient holds the first communication device, and the cloud server comprises a health data collection module used for obtaining subjective health data and objective health data of the patient; the objective health recognition module is used for determining a first health state of the patient according to the objective health data; the subjective health recognition module is used for recognizing emotion information of the patient according to the objective health data; the reminding propaganda and education module is used for determining a pushing time point according to the living habits of the patient, the first health state and a preset treatment scheme, and pushing treatment reminding and health propaganda and education data to the first communication equipment at the pushing time point in combination with the emotion information of the patient; according to the system provided by the invention, an omnibearing and intelligent health management and adjuvant therapy platform is provided, help can be provided for the patient physiologically and psychologically at the same time, and the compliance of the patient to treatment is improved.
Owner:ZUNYI MEDICAL UNIV ZHUHAI CAMPUS

Handheld red light pain therapy device

ActiveCN309469692SPain therapyPhysical medicine and rehabilitation
1. The name of this design product: Handheld red light therapy device for pain. 2. Purpose of this design product: This design product is used for auxiliary treatment of soft tissue injuries and chronic pain. 3. The key point of the design of this product lies in its shape. 4. The picture or photo that best illustrates the design points: Stereoscopic drawing 1.
Owner:WUHAN ZJZK TECHNOLOGY CO LTD

Medical bed for adjuvant therapy

The utility model belongs to the technical field of medical equipment, and provides a medical bed for adjuvant therapy, which comprises a base, a bed board component and a lifting mechanism, and the lifting mechanism is used for connecting the base with the bed board component and driving the bed board component to lift; the lifting mechanism comprises at least three lifting pieces which are distributed in an axial symmetry mode with the gravity center of the medical bed as the center. The bed board assembly comprises a bed board supporting frame, the bed board supporting frame comprises a plurality of pieces of angle aluminum, a frame structure is formed through the multiple pieces of angle aluminum, and at least one piece of angle aluminum is used for providing a horizontal sliding rail. The medical bed is simple in structure, high in structural reliability and light in product weight, manufacturing, transporting and installing processes can be simplified, the transporting space requirement and the installing position bearing requirement for a user are lowered, and the acceptability of the user is improved.
Owner:CHONGQING HAIFU (HIFU) TECHNOLOGY CO LTD

Grape seed protein peptide with ACE inhibitory activity and preparation method thereof

The invention discloses a grape seed protein peptide with ACE inhibitory activity and a preparation method thereof, and belongs to the field of comprehensive utilization of wine fermentation byproducts. The invention provides a grape seed protein peptide with ACE (Angiotensin Converting Enzyme) inhibitory activity. The grape seed protein peptide is FFYPL, SGMFPFP or WFFPGPR. The grape seed protein peptide disclosed by the invention can be used for medicines, health-care products or dietary supplements, or can be used as a food base material to be added into common foods such as drinks, dairy products and the like; as used for prevention or auxiliary treatment of hypertensive patients or people suffering from chronic metabolic comprehensive disorder diseases with diseases such as obesity and heart and cerebral vessels, the product has a wide application prospect in the fields of functional foods, medicines, health care products and the like.
Owner:JIANGNAN UNIV

Application of bifidobacterium longum in improving immunity and preparing product for preventing, treating and / or adjunctively treating rhinitis

The invention belongs to the technical field of microorganisms, and particularly relates to application of bifidobacterium longum in improving immunity and preparing products for preventing, treating and / or assisting in treating rhinitis. The preservation number of the bifidobacterium longum is GDMCC No: 65969, and the bifidobacterium longum can reduce the levels of MDA and NO in serum of mice and improve the activity of SOD and CAT and the content of GSH so as to relieve oxidative stress injury; inflammatory cell infiltration of nasal mucosa is reduced, and lung tissue inflammatory mediator level and inflammation-related gene expression are reduced to inhibit inflammation; th1 / Th2 immune balance is regulated, Th2 type cytokines are reduced, Th1 type cytokines are increased, and the high-dosage effect is close to that of loratadine. The strain has a treatment effect on allergic rhinitis through multiple mechanisms, and a new choice is provided for treatment of the strain.
Owner:THANKCOME BIOLOGICAL SCI & TECH CO LTD

Multi-mode biofeedback ear vagus nerve adaptive stimulation device and method

The invention relates to the technical field of medical instruments, in particular to a multi-mode biological feedback ear vagus nerve self-adaptive stimulation device and method.The device comprises a host, a stimulation electrode, a signal collection bracelet and an electroencephalogram collection module, and the host comprises core hardware configuration and a power management system; the signal acquisition bracelet comprises an ECG module, a PPG module, a GSR module, a six-axis acceleration sensor and the like. The ear vagus nerve stimulation parameter can be dynamically adjusted through real-time analysis of multi-mode data such as electrocardio, electroencephalogram, heart rate variability, respiration-heart rate synchronism and emotional state, personalized precise treatment is achieved, meanwhile, the wearing comfort and the durability of the device are improved, and the application range is wide. The traditional Chinese medicine composition can be used for auxiliary treatment of various diseases such as inflammatory bowel disease, epilepsy, chronic insomnia, depression, chronic pain, anxiety disorder, post-traumatic stress disorder and autonomic nerve dysfunction, and the functions of a nervous system are adjusted and the symptoms of a patient are improved by accurately stimulating the vagus nerve in the auricular concha area.
Owner:YANCHENG HOSPITAL OF TRADITIONAL CHINESE MEDICINE

A cervical spine assisted treatment device for pain department nursing

The present invention discloses a cervical spine auxiliary treatment device for pain department nursing, which relates to the technical field of medical auxiliary instruments and includes: a main body mechanism, on one side of the inner wall of the main body mechanism, an auxiliary treatment mechanism is fixedly installed, the auxiliary treatment mechanism includes a nursing frame, an internal motor is fixedly inserted inside the nursing frame, the rotating end of the internal motor is fixedly connected to a threaded rod, and two internal gears are thread-driven on the outer surface wall of the threaded rod. In the present invention, through the coordinated work within the rotation speed control component, the rotation speed of the internal motor can be precisely controlled, and then the motion states of the massage roller and the staggered extrusion roller can be accurately adjusted. It can flexibly adjust parameters such as treatment intensity and frequency according to the conditions and needs of different patients, meet the personalized treatment requirements, not only improve the treatment effect, but also can adjust the treatment according to the conditions of different patients, improve the adaptability of the device, and avoid the problem of secondary injury to patients caused by inaccurate adjustment.
Owner:CHENGDU MILITARY GENERAL HOSPITAL OF PLA

Application of bifidobacterium animalis in preparation of product for preventing, treating or adjunctively treating pneumonia

The invention relates to application of bifidobacterium animalis in preparation of a product for preventing, treating or adjunctively treating pneumonia, and belongs to the technical field of microorganisms. The invention aims to solve the technical problem that the existing treatment of acute lung injury (ALI) / acute respiratory distress syndrome (ARDS) is mainly based on supportive means and lacks special-effect treatment drugs. According to the key point of the technical scheme, a new strain, namely the Bifidobacterium animalis ORG01 is provided, the preservation number is GDMCC NO: 67122, and the strain has good technical effects in the aspects of improving the acute lung injury effect, the strain stability, the product application convenience and the like. According to an experimental test, the bifidobacterium animalis ORG01 disclosed by the invention can be used for remarkably recovering the lung organ index of an LPS-induced acute lung injury model mouse, the TNF-alpha content in serum and the mRNA expression level of IL-6 in lung tissues to normal levels.
Owner:THANKCOME BIOLOGICAL SCI & TECH CO LTD

Kidney cancer recurrence risk prediction method based on deep learning model

PendingCN120707942AImage enhancementImage analysisNetwork modelKidney tumor
The invention provides a kidney cancer recurrence risk prediction method based on a deep learning model, and relates to the technical field of deep learning, and the method comprises the steps: collecting an image data set for kidney cancer high recurrence risk prediction; carrying out registration on the collected multi-stage enhanced CT image; constructing and training a kidney tumor automatic detection and segmentation model; carrying out ROI positioning cutting and quality control; and constructing a deep learning model for renal cancer recurrence risk prediction based on the multi-modal convolutional neural network, and realizing renal cancer recurrence risk prediction through the constructed prediction network model. According to the method, the multi-phase enhanced CT image of the kidney cancer patient is analyzed through the deep learning model, the tumor postoperative recurrence risk is predicted, an objective basis is provided for a clinician to make an individualized follow-up visit scheme and an auxiliary treatment decision, and excessive treatment of a low-risk patient and insufficient treatment of a high-risk patient are avoided.
Owner:ZHONGSHAN HOSPITAL FUDAN UNIV

Auxiliary treatment system and method for difficult-to-reverse suppurative periapical periodontitis

ActiveCN120661268AImage enhancementImage analysisInflammatory factorsPeriapical disease
The invention relates to the technical field of dental intelligent adjuvant therapy, and discloses an adjuvant therapy system and method for difficult-to-inverse suppurative periapical periodontitis, and the system comprises a multi-modal image fusion module which fuses CT / OCT images to generate a three-dimensional diagram, segments an infected region through a lightweight CNN, and outputs a probability diagram; the reinforcement learning debridement navigation module is used for optimizing the dentin injury risk by combining a biological membrane thickness dynamic planning path on the basis of a DDPG algorithm; the intelligent medicine control module is used for positioning a catheter according to an infection map, triggering medicine release by a pH / enzyme sensor and adjusting delivery pressure by PID; the biosensor monitoring module is used for detecting inflammatory factors, predicting the recurrence risk through LSTM, and triggering image rescanning and path updating when a threshold value is exceeded. Through multi-modal image fusion, reinforcement learning dynamic debridement navigation, microenvironment response type drug control and time sequence prediction closed-loop feedback, accurate elimination and relapse active inhibition of periapical periodontitis focuses are realized.
Owner:FOURTH MILITARY MEDICAL UNIVERSITY

Lactobacillus paracasei and application thereof

The invention belongs to the technical field of microorganisms, and particularly discloses lactobacillus paracasei and application thereof, the lactobacillus paracasei is named as lactobacillus paracasei Jlus66, the lactobacillus paracasei is preserved in China General Microbiological Culture Collection Center on March 31, 2021, the preservation address is No.3, No.1 Yard, Beichen West Road, Chaoyang District, Beijing, and the preservation number is CGMCC No.22101. The lactobacillus paracasei is named as lactobacillus paracasei Jlus66. The lactobacillus paracasei Jlus66 has the obvious beneficial effects in the treatment of the alopecia areata, and the obvious beneficial effects comprise the immune regulation, the anti-oxidation and anti-inflammatory effects and the optimization of the intestinal tract-skin axis. In addition, the medicine is high in safety and small in side effect, so that the medicine becomes a promising adjuvant therapy means.
Owner:JILIN UNIVERSITY

Dynamic intelligent fixing device for lower limb rehabilitation

The invention relates to a dynamic intelligent fixing device for lower limb rehabilitation, which belongs to the technical field of medical instruments and comprises a dynamically adjustable leg supporting structure, a self-adaptive foot fixing device, a multi-modal stimulation system, a double-shaft linkage movement mechanism and an intelligent regulation and control system. The dynamic adjusting structure and the self-adaptive fixing device can adapt to different leg circumferences, foot types and joint motion ranges, and comfortable fixing and standard movement of a patient are guaranteed; the multi-mode stimulation system is combined with mechanical movement, pneumatic massage and myoelectricity stimulation to synergistically promote blood circulation of the lower limbs; the intelligent regulation and control system collects multi-dimensional physiological data in real time and dynamically optimizes motion parameters and stimulation intensity. The device solves the problems that an existing device is poor in adaptability, single in stimulation, lagged in regulation and control and the like, individualized precise adjuvant therapy is achieved, the lower limb rehabilitation effect and clinical benefits of postoperative lower limb fixation and VTE prevention are effectively improved, and meanwhile the operation complexity of medical staff is reduced.
Owner:THE FIRST AFFILIATED HOSPITAL OF ARMY MEDICAL UNIV

Radix asparagi homogeneous acidic polysaccharide as well as preparation method and application thereof

PendingCN121449776AAntipyreticDigestive systemNatural sourcePectic polysaccharide
The invention provides a radix asparagi homogeneous acidic polysaccharide. The radix asparagi homogeneous acidic polysaccharide contains pectic polysaccharide which is shown as a formula 1, takes rhamnogalacturonidan I (RG-I) as a core and has a homopolygalacturonic acid (HG) structural domain. The invention further provides a preparation method and application of the radix asparagi homogeneous acidic polysaccharide. The asparagi pectin polysaccharide with a new structure is found for the first time, and the asparagi pectin polysaccharide has the effect on acute lung injury. The acidic polysaccharide disclosed by the invention has the advantage of anti-ALI activity, realizes synergistic protection of intestine-lung double target regions, has anti-inflammatory and anti-oxidation double activities, is natural in source and high in biological safety, and is suitable for long-term adjuvant therapy of acute lung injury.
Owner:CHENGDU INST OF CHINESE HERBAL MEDICINE +1

Constipation auxiliary treatment appliance and use method thereof

PendingCN120859827ACavity massageVibration massageReflexRectum wall
The invention relates to the technical field of medical instruments, in particular to a constipation adjuvant therapy appliance and a using method thereof.The constipation adjuvant therapy appliance comprises an insertion tube, a vibration sleeve is arranged at the inner end of the insertion tube, and a vibration motor is arranged in the vibration sleeve; the outer end of the insertion pipe is connected with a medium pipeline used for inputting or outputting a medium into or out of a pipe cavity of the insertion pipe. A plurality of protruding blocks are arranged on the pipe wall of the outer side of the insertion pipe. Through mechanical pressure generated by expansion of the insertion tube and the adjusting cavity of the insertion tube and local stimulation of the outer side protruding block on the rectum wall, low-frequency vibration of the vibration motor in the vibration sleeve is combined, a rectum wall mechanical receptor and a nerve conduction path are cooperatively activated in a multi-mode mode, defecation reflex is triggered, and therefore targeted intervention on defecation reflex disorder of a constipation patient is achieved. The defect that a traditional therapy does not touch a neural mechanism is overcome, and a comprehensive solution from physiological reflex activation to mechanical power enhancement is provided for constipation treatment.
Owner:JIANGSU CHONGHENG MEDICAL TECH CO LTD

Composite combined preparation for synergistically treating and conditioning diabetes mellitus

The invention discloses a composite combined preparation for synergistically treating and conditioning diabetes, relates to the technical field of foods, health foods or dietary supplements for adjuvant therapy and health care of diabetes, and in particular relates to a composite combined preparation for synergistically treating and conditioning diabetes. The preparation comprises albumin peptide, saussurea involucrata culture, vitamin B1, vitamin B2, wheat oligopeptide, corn oligopeptide, collagen peptide, mulberry leaf extract, rhizoma polygonati extract, sea-buckthorn extract, isomaltitol, maltodextrin, ginseng extract and bitter gourd extract. Through the synergistic effect of all the components, comprehensive auxiliary conditioning on diabetes is realized from multiple targets of maintaining colloid osmotic pressure and nutrition, regulating glycolipid metabolism in multiple ways, protecting pancreatic beta cell functions, enhancing insulin sensitivity, preventing nerve and blood vessel complications, meeting special diet requirements and the like. The composition can be prepared into food, health-care food or dietary supplement and other dosage forms.
Owner:SHANDONG JIEDIAO CARBON SINK CONSTRUCTION ENGINEERING GROUP CO LTD

Gridding and attention mechanism-based point cloud complementation tumor three-dimensional reconstruction system

The invention discloses a point cloud complementation tumor three-dimensional reconstruction system based on gridding and an attention mechanism, and relates to the technical field of medical image processing, and the system comprises a data acquisition module, an image preprocessing module, and a model reconstruction module. The data acquisition module is used for collecting and acquiring two-dimensional CT image data; the image preprocessing module is used for preprocessing the two-dimensional CT image; and the model reconstruction module is used for performing three-dimensional reconstruction on the preprocessed two-dimensional CT image data to generate a three-dimensional medical image and a point cloud completion network comprising grids and geometric perception Transformer, extracting contour information from the two-dimensional segmentation mask, and predicting and reconstructing complete surface shapes of the liver and the tumor from the contour information. Therefore, in order to solve the problems existing in existing medical images, more accurate three-dimensional liver and tumor morphological reconstruction is provided for clinic, the accuracy of disease diagnosis and formulation of an auxiliary treatment scheme are improved, risks in an operation are reduced, and the success rate of the operation is improved.
Owner:CHINA UNIV OF PETROLEUM (EAST CHINA)

Airway stent

The invention provides an airway stent, and relates to the technical field of airway stents. Ozone gas is contained in the storage bottle body, the internal space of the storage bottle body is in a circular ring shape, and a sealing bottle cap is buckled on the top of the storage bottle body; the memory metal support is located in the annular space in the storage bottle body. A rubber sealing ring is installed in the sealing bottle cap, the storage bottle body is sleeved with a movable sleeve shell, and the top of the movable sleeve shell is connected with the sealing bottle cap. A spring is connected into the movable sleeve shell and connected with the storage bottle body. When the memory metal stent is placed in the airway of a patient, the melt degradation film is degraded by body fluid, the inhibition medicine is slowly released from the slow release micropores, and granulation hyperplasia in the airway is inhibited for a long time. The problems that an existing medical airway stent mostly adopts a coating film drug-containing mode for adjuvant therapy, due to the fact that an outer side coating film is thin, the drug content is small, the drug contained in the coating film can be completely released in a short time, and the effect is not long enough are solved.
Owner:FOURTH MILITARY MEDICAL UNIVERSITY

System and method for ai assisted therapeutic micro-interventions in care at home

PendingUS20250292914A1Medical communicationMedical data miningHome care nursingNetworked system
A distributed healthcare network system stores intervention, context, and communication rules in databases, defining responses to patient-related events. Context includes factual circumstances tied to the patient. The system constructs a distributed ledger for each patient, incorporating their profile, therapeutic events, and context indicators based on predefined rules. Interventions are selected according to patient context and communicated to relevant network nodes, with records added to the ledger. AI models trained on patient data help identify subtle scenarios from context indicators and suggest alternative actions. Intervention rules rely on fixed thresholds and AI-driven analysis to determine appropriate responses. The ledger, distributed across the network, ensures transparency, enhances communication among patients, providers, and payers, and streamlines healthcare transactions. This method enables efficient decision-making, ensures accurate documentation, and improves healthcare coordination by maintaining an immutable, accessible record of patient interactions, interventions, and contextual factors.
Owner:LIFEGUARD HEALTH NETWORKS

Application of sea cucumber polysaccharide in process of assisting anti-PD-1 in treating colon cancer

The invention discloses application of sea cucumber polysaccharide in the process of assisting anti-PD-1 in treating colon cancer, and belongs to the technical field of medicine. The SCP pretreatment is combined with the anti-PD-1 immunotherapy, so that the curative effect of the anti-PD-1 immunotherapy is remarkably enhanced. Researches show that single use of the SCP has no significant inhibition effect on tumor growth, but the SCP can significantly enhance the anti-tumor effect of anti-PD-1 treatment. The SCP combined with anti-PD-1 treatment can increase the number of CD8 < + > T lymphocytes, especially IFN-gamma < + > cytotoxic CD8 < + > T cells, and reduce the proportion of regulatory CD4 < + > T cells at the same time. The SCP improves the immunotherapy effect by adjusting intestinal flora and increasing the relative abundance of beneficial bacteria such as bifidobacteria and fecal bacillus, and fecal flora transplantation experiments show that the tumor immunotherapy enhancing effect of the SCP is at least partially mediated by the intestinal flora.
Owner:DALIAN POLYTECHNIC UNIVERSITY

Neurotransmitter-entrapped ginsenoside liposome as well as preparation method and application thereof

The invention provides a neurotransmitter-entrapped ginsenoside liposome and a preparation method thereof, the neurotransmitter-entrapped ginsenoside liposome is prepared from the following raw materials: ginsenoside, neutral phospholipid and acetylcholine, and the mass ratio of ginsenoside to neutral phospholipid to acetylcholine is (6-10): (10-20): (10-15). The lipidosome can effectively inhibit intestinal inflammation reaction, relieve intestinal inflammation damage, repair damaged ENS and improve intestinal functions, is suitable for being used as a treatment or adjuvant treatment mode of IBD, especially for regulation and control of an intestinal mucosa immune system of an IBD patient and protection and repair effects on nerves, improves treatment targeting, and has a good application prospect. The preparation method is simple and convenient, high in safety and excellent in economic benefit and social benefit.
Owner:AFFILIATED HUSN HOSPITAL OF FUDAN UNIV

Intervertebral foramen mirror

1. Name of the product in this design: Percutaneous endoscopic discectomy. 2. Purpose of this design: This design is used for observation, diagnosis and adjunctive treatment of spinal parts such as intervertebral foramina and intervertebral discs. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: a 3D model.
Owner:JIANGXI MICRO VISION OPTICAL TECH CO LTD

Plasma lipid isomer biomarker for predicting survival benefit of neoadjuvant therapy of breast cancer and application of plasma lipid isomer biomarker

The invention relates to a plasma lipid isomer biomarker for predicting survival benefit of neoadjuvant therapy of breast cancer and application of the plasma lipid isomer biomarker. The plasma lipid isomer biomarker is PC 17: 1 (n-8) 18: 1 (n-7), PC 18: 018: 1 (n-7), PC 14: 018: 1 (n-10), PE 16: 018: 1 (n-7), PE 14: 018: 1 (n-7) and PC 16: 1 (n-7) 18: 1 (n-9). The invention also constructs a breast cancer NAT survival benefit prediction model. According to the method, the survival benefit probability of the patient can be accurately evaluated, and a scientific basis for personalized treatment decision is provided for clinic, so that a more accurate treatment scheme is realized, the treatment effect of the patient is optimized, and excessive treatment or insufficient treatment is avoided.
Owner:CANCER INST & HOSPITAL CHINESE ACADEMY OF MEDICAL SCI +1