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962 results about "Adjunctive treatment" patented technology

The purpose of adjunctive therapy, often called complementary therapy, is to increase the benefits of the initial treatment of a disorder by prescribing additional medications and/or treatments. Several examples of disorders and diseases that are generally treated with adjunctive therapy include cancer,...

Use of reboxetine to treat narcolepsy

ActiveUS12246023B2Organic active ingredientsNervous disorderPharmaceutical drugNarcolepsy with cataplexy
Described herein are methods of treating narcolepsy with cataplexy, comprising administering reboxetine to a human being in need thereof. Reboxetine may also be used in the manufacture of a medicament for the treatment of narcolepsy with cataplexy. Also disclosed herein are kits comprising a pharmaceutical composition comprising reboxetine and instructions to use the pharmaceutical composition to treat narcolepsy with cataplexy in a human being.
Owner:AXSOME THERAPEUTICS INC

Auxiliary expectoration control method and device

The invention provides an expectoration auxiliary control method and device. The method comprises the steps that audio signals of breathing sounds and cough sounds at multiple positions of the chest of a patient are collected through an audio sensor array, and a standardized audio feature data set is obtained through noise reduction, segmentation and feature extraction; a dynamic weighted graph model is constructed, and a random edge sampling algorithm and a parallel batch processing dynamic algorithm are combined to analyze and obtain a sputum viscosity index and a sputum distribution position map; based on the result, mapping the vibration parameter space into an unweighted disk diagram, and obtaining a personalized vibration treatment scheme by using a shortest path algorithm; in combination with the real-time breathing cycle of the patient, working parameters of the sound wave vibrator and the negative pressure suction device are synchronously controlled, and a coordinated and consistent multi-mode treatment execution instruction is obtained; and collecting real-time feedback data in treatment, and dynamically adjusting working parameters through reinforcement learning to obtain an optimized expectoration adjuvant therapy scheme. Intelligent adjustment can be achieved based on the real-time breathing state and sputum characteristics of the patient, the expectoration efficiency is improved, and discomfort of the patient is reduced.
Owner:THE FIRST AFFILIATED HOSPITAL ZHEJIANG UNIV COLLEGE OF MEDICINE

Back cushion type ultraviolet therapeutic apparatus

ActiveCN119792819ALight therapyVitamin supplementationControl system
The invention belongs to the technical field of ultraviolet therapeutic instruments, and particularly relates to a back cushion type ultraviolet therapeutic instrument which comprises a phototherapy module, a handle, a supporting module and a control system, the phototherapy module is arranged on the supporting module, the phototherapy module is electrically connected with the control system, and the control system is electrically connected with the handle. According to the back cushion type ultraviolet therapeutic apparatus, vitamin D is supplemented through irradiation of ultraviolet light, the back cushion type ultraviolet therapeutic apparatus is placed on a sofa, a seat and a back of a user during use, through the unique structural design and the advanced narrow-spectrum ultraviolet light technology, generation of the vitamin D can be efficiently promoted, other diseases can be prevented and treated in an auxiliary mode, and the treatment effect is good. And meanwhile, the device has the advantages of high safety, simplicity and convenience in operation, economy, practicability and the like, and provides better treatment experience for users.
Owner:SHANXI GUANGYISHENG TECHNOLOGY CO LTD

Preparation method and application of lactic acid bacteria metagen

The invention belongs to the technical field of microorganisms, and particularly relates to probiotic characteristics of lactic acid bacteria and a relieving effect of a metagen of the lactic acid bacteria on pulmonary fibrosis. The invention discloses pediococcus pentosaceus ZFML001, and the preservation number of the pediococcus pentosaceus ZFML001 is CCTCC (China Center for Type Culture Collection) NO: M 2024601. The invention also provides a metagen prepared from the pediococcus pentosaceus ZFML001 at the same time, and provides an application of the metagen in preparation of a medicine for relieving or assisting in treatment of pulmonary fibrosis. The invention further provides the application of the metagen in preparation of a medicine for relieving or assisting in treatment of pulmonary fibrosis.
Owner:ZHEJIANG GONGSHANG UNIVERSITY

Injectable hydrogel for photo-thermal adjuvant therapy of periodontitis and preparation method of injectable hydrogel

The invention discloses injectable hydrogel for photo-thermal adjuvant therapy of periodontitis and a preparation method, and belongs to the technical field of high polymer material preparation, the preparation method comprises the following steps: reacting MXene dispersion liquid with epigallocatechin gallate and MgSO4; then sequentially carrying out ultrasonic treatment, centrifugation, washing and freeze-drying to obtain a multifunctional nanosheet MP-Mg; adding the multifunctional nanosheet MP-Mg into an oxidized gellan gum aqueous solution, and carrying out a mixed reaction to obtain a solution A; mixing the quaternary ammonium salt chitosan aqueous solution and the carboxymethyl chitosan aqueous solution in equal volume, and reacting to obtain a solution B; and mixing the solution A and the solution B in equal volume for reaction. The hydrogel prepared by the preparation method disclosed by the invention has injectability, photo-thermal responsiveness, biological membrane penetrability, synergistic antibacterial property and long-acting anti-inflammatory property, and an innovative and practical photo-thermal adjuvant therapy platform is provided for clinical treatment of periodontitis.
Owner:JILIN UNIVERSITY

Virtual reality training system and method for fireman stress disorder adjuvant therapy

The invention provides a virtual reality training system and method for fireman stress disorder adjuvant therapy, the fireman training system and method based on virtual reality are provided by utilizing the development of the virtual reality technology and the heart rate variability monitoring technology, the virtual reality environment is selected and adjusted in combination with multiple dimensions, and the fireman stress disorder adjuvant therapy effect is improved. On one hand, the fire-fighting task processing capability of the firefighter can be trained, and on the other hand, the post-traumatic stress disorder of the firefighter can be treated in an auxiliary manner, so that the firefighter is helped to overcome the fear of trauma and high pressure in the fire-fighting task, and the post-traumatic stress disorder is prevented and treated in an auxiliary manner; the cure rate of the stress disorder of the group of firemen is effectively improved, and the prevalence rate of the stress disorder is reduced. Moreover, according to the scheme, through multi-level personalized adjustment, it is ensured that the adjuvant therapy training scheme better meets the unique requirements of each fireman according to individual characteristics, individual differences, psychological states and physiological states, and the training effect is effectively improved.
Owner:HANGZHOU XINJING TECH CO LTD

Clinical gastrointestinal decompression equipment for digestive system department

The invention provides clinical gastrointestinal decompression equipment for the digestive system department, and belongs to the technical field of adjuvant therapy. Comprising a mounting mechanism; a connecting arm is fixedly connected to the front face of the mounting mechanism, a power mechanism is mounted on the side, away from the mounting mechanism, of the connecting arm through bolts, and a rail frame is fixedly mounted on the side, away from the mounting mechanism, of the power mechanism. Through the arrangement, the equipment can be installed on the side edge of a sickbed during use, can adapt to different occasions, can adjust the height to meet the requirements of different patients, realizes the transverse and longitudinal synchronous displacement of the massage mechanism on the abdomen of the patient through the motor driving of the power and linkage mechanism, is large in massage range and excellent in massage effect, can replace manual massage, is not influenced by the external environment, and is suitable for popularization and application. The massage decompression mechanism can be used for hot compress massage, the temperature can be adjusted, the pressure of the gastrointestinal tract is further relieved, and better treatment experience is brought to a patient.
Owner:中国人民解放军总医院第八医学中心

System and method for performing cranial nerve stimulation based on olfactory, auditory and synchronous magnetomotive stimulation

The invention discloses a system and method for performing cranial nerve stimulation based on olfaction, hearing and synchronous magnetomotive stimulation, and the system comprises a magnetic therapy bearing main body which is a magnetic therapy helmet, serves as a basic bearing structure of the system, and is used for installing all functional assemblies, providing magnetic therapy physical auxiliary stimulation, and achieving the cooperation of magnetic therapy and multi-mode stimulation; the olfactory stimulation subsystem is used for providing olfactory stimulation with precise regulation and control; the auditory stimulation subsystem is used for providing personalized audio stimulation; the magnetomotive stimulation subsystem is used for providing magnetomotive stimulation; the nerve stimulation cooperation subsystem is used for planning multi-mode stimulation as a whole and achieving regulation and control. Through the synergistic effect of olfactory stimulation, auditory stimulation and magnetomotive stimulation, three major neural pathways of olfactory, auditory and somatosensory can be activated at the same time, multi-dimensional nerve resonance is formed, the brain wave synchronization degree is remarkably improved, and the adjuvant therapy effect on Alzheimer's disease, cognitive impairment and other diseases is superior to that of single-mode stimulation.
Owner:RONGCHEN (HEFEI) BIOTECHNOLOGY CO LTD

Microcatheter shaping methods, systems and related devices for adjuvant treatment of aneurysms

The invention provides a micro-catheter shaping method and system for adjuvant therapy of aneurysm and related equipment, and relates to the technical field of image processing, and the micro-catheter shaping method for adjuvant therapy of aneurysm comprises the steps: obtaining an aneurysm to be treated and an image corresponding to a blood vessel where the aneurysm is located; according to the image, performing overall modeling on the aneurysm and a blood vessel where the aneurysm is located to obtain a corresponding global model, the global model including an aneurysm model and a blood vessel model; according to the global model, first key parameters corresponding to the aneurysm model and second key parameters corresponding to the blood vessel model are obtained, the micro catheter is shaped based on the first key parameters and the second key parameters, physical laws and the shaping form of the head end of the aneurysm can be considered, it can be guaranteed that the head end of the micro catheter is fed into the aneurysm, and the shaping accuracy is improved. And the in-place rate and the stability of the operation are improved.
Owner:UNION STRONG (BEIJING) TECH CO LTD

Application of ackermann muciniphile or external vesicles thereof in preparation of drugs for treating schistosomiasis

The invention belongs to the technical field of biological medicines, and relates to application of Ackermann muciniphile or its external vesicles in preparation of a drug for treating schistosomiasis. The anti-infection immunity of a host is enhanced by adjusting intestinal flora balance (recovering diversity and composition) and improving immune response (adjusting macrophage, CD8 + T cell recruitment and Th1 / Th2 balance); meanwhile, the intestinal barrier function is improved, and pathogen invasion and inflammation are reduced; hepatic granuloma and hepatic fibrosis caused by schistosome infection are obviously relieved, and the liver function is improved; the key effect of the MIF gene in immunoregulation is disclosed, and a new direction is provided for schistosomiasis immunotherapy. Besides, the probiotics are high in treatment safety and free of obvious side effects, can be combined with chemotherapy to enhance the curative effect and reduce the side effects and drug resistance of chemical drugs, provides a lasting and comprehensive adjuvant therapy scheme for the schistosomiasis, and has important clinical application potential.
Owner:HUBEI UNIV OF MEDICINE

Anorectal disease auxiliary treatment monitoring system and method based on Lingshen extract

The invention relates to the technical field of adjuvant therapy monitoring, in particular to an anorectal disease adjuvant therapy monitoring system and method based on a radix scrophulariae extract. The method comprises two stages of system initialization and adjuvant therapy monitoring, in the initialization stage, initialization setting is completed, and a dynamic monitoring code is generated to guarantee data transmission security; in the auxiliary treatment stage, baseline data are collected, abnormal values are removed, then personalized baselines are generated, the drug dosage and the release rate are adjusted according to the baseline data, meanwhile, pressure, temperature, blood flow and electrophysiological data are monitored in real time, key indexes are calculated, monitoring labels are generated, the physiological indexes are standardized, the treatment effect is comprehensively evaluated, and classification is conducted. The dynamic trend is analyzed by adopting a polynomial fitting method, an evaluation result is generated, the drug release rate and dosage are dynamically optimized in combination with real-time monitoring data and patient feedback, and fine treatment is further performed by adopting a feedback adjustment mechanism. According to the invention, efficient auxiliary treatment and intelligent monitoring of anorectal diseases are realized.
Owner:CHANGCHUN UNIV OF CHINESE MEDICINE

Anti-oxidation nano material based on self-assembly of traditional Chinese medicine and copper ions and preparation method of anti-oxidation nano material

The invention belongs to the field of nano-medicine and traditional Chinese medicine, and particularly discloses an antioxidant nano-material based on self-assembly of traditional Chinese medicine and copper ions and a preparation method thereof.The nano-material is prepared from BPCu nano-particles formed by self-assembly of berberine and procyanidine B2 under induction of the copper ions, the BPCu nano-particles are further subjected to surface modification through polyvinylpyrrolidone, and the antioxidant nano-material is prepared. And the stably dispersed PVP-coated BPCu nano structure is obtained. The material is small in particle size, uniform in distribution, good in water solubility and storage stability, excellent in free radical scavenging capacity and catalase-like activity and suitable for adjuvant therapy of oxidative stress related diseases, and the preparation method is easy and convenient to operate, does not need an organic solvent and has good industrialization and disease treatment potential.
Owner:LULIANG PEOPLES HOSPITAL (LÜLIANG HOSPITAL AFFILIATED TO SHANXI MEDICAL UNIV ELEVENTH CLINICAL COLLEGE OF SHANXI MEDICAL UNIV)

Ankle joint fixator capable of massaging

The utility model discloses an ankle joint fixator capable of massaging, which comprises a sole supporting part and a leg supporting part, and belongs to the technical field of medical auxiliary treatment equipment. According to the utility model, the massage device is arranged on the leg supporting part, so that the legs of a patient can be heated and massaged, and blood circulation is promoted; a plurality of air holes are formed in the leg supporting part, so that air circulation can be increased, and local ventilation and dryness are kept; the foot sole supporting part and the leg supporting part are movably connected, the angle between the foot sole supporting part and the leg supporting part can be controlled by adjusting the length of the telescopic rod during wearing, and a patient is better helped to play a fixing and supporting role.
Owner:SHANDONG LIANGSHI CHONGDETANG MEDICAL TECH CO LTD

Hemodialysis fatigue patient-oriented health monitoring and propaganda treatment system

The embodiment of the invention provides a hemodialysis fatigue patient-oriented health monitoring and propaganda treatment system, which comprises a cloud server and a first communication device, the patient holds the first communication device, and the cloud server comprises a health data collection module used for obtaining subjective health data and objective health data of the patient; the objective health recognition module is used for determining a first health state of the patient according to the objective health data; the subjective health recognition module is used for recognizing emotion information of the patient according to the objective health data; the reminding propaganda and education module is used for determining a pushing time point according to the living habits of the patient, the first health state and a preset treatment scheme, and pushing treatment reminding and health propaganda and education data to the first communication equipment at the pushing time point in combination with the emotion information of the patient; according to the system provided by the invention, an omnibearing and intelligent health management and adjuvant therapy platform is provided, help can be provided for the patient physiologically and psychologically at the same time, and the compliance of the patient to treatment is improved.
Owner:ZUNYI MEDICAL UNIV ZHUHAI CAMPUS

Breathing movement assisting device for young pulmonary tuberculosis patient

The invention discloses a respiratory movement assisting device for young pulmonary tuberculosis patients, which comprises a rectangular fixing band, an elastic band, a first elastic band and a second elastic band, the breathing assisting structure is arranged on one side of the fixing belt, the breathing assisting structure comprises a round machine shell and an oxygen tank, a compressor is fixedly installed in the round machine shell, and an electric control valve is fixedly installed at the top of the oxygen tank; according to the breathing assisting device, under the action of the breathing assisting structure, the oxygen tank is matched with the mask to assist breathing of a patient in the movement process, and meanwhile, under the action of the compressor matched with the atomized liquid frame, the patient can be prevented from breathing in the movement process, so that the patient does not feel comfortable in the movement process. By means of the device, the medicine capable of breathing stably can be inhaled for auxiliary treatment, so that in the strong exercise process of young patients, unsmooth breathing and dyspnea caused by lung function damage are avoided, and overall exercise is safer.
Owner:HEILONGJIANG POLYTECHNIC

Handheld red light pain therapy device

ActiveCN309469692SPain therapyPhysical medicine and rehabilitation
1. The name of this design product: Handheld red light therapy device for pain. 2. Purpose of this design product: This design product is used for auxiliary treatment of soft tissue injuries and chronic pain. 3. The key point of the design of this product lies in its shape. 4. The picture or photo that best illustrates the design points: Stereoscopic drawing 1.
Owner:WUHAN ZJZK TECHNOLOGY CO LTD

Medical bed for adjuvant therapy

The utility model belongs to the technical field of medical equipment, and provides a medical bed for adjuvant therapy, which comprises a base, a bed board component and a lifting mechanism, and the lifting mechanism is used for connecting the base with the bed board component and driving the bed board component to lift; the lifting mechanism comprises at least three lifting pieces which are distributed in an axial symmetry mode with the gravity center of the medical bed as the center. The bed board assembly comprises a bed board supporting frame, the bed board supporting frame comprises a plurality of pieces of angle aluminum, a frame structure is formed through the multiple pieces of angle aluminum, and at least one piece of angle aluminum is used for providing a horizontal sliding rail. The medical bed is simple in structure, high in structural reliability and light in product weight, manufacturing, transporting and installing processes can be simplified, the transporting space requirement and the installing position bearing requirement for a user are lowered, and the acceptability of the user is improved.
Owner:CHONGQING HAIFU (HIFU) TECHNOLOGY CO LTD

Grape seed protein peptide with ACE inhibitory activity and preparation method thereof

The invention discloses a grape seed protein peptide with ACE inhibitory activity and a preparation method thereof, and belongs to the field of comprehensive utilization of wine fermentation byproducts. The invention provides a grape seed protein peptide with ACE (Angiotensin Converting Enzyme) inhibitory activity. The grape seed protein peptide is FFYPL, SGMFPFP or WFFPGPR. The grape seed protein peptide disclosed by the invention can be used for medicines, health-care products or dietary supplements, or can be used as a food base material to be added into common foods such as drinks, dairy products and the like; as used for prevention or auxiliary treatment of hypertensive patients or people suffering from chronic metabolic comprehensive disorder diseases with diseases such as obesity and heart and cerebral vessels, the product has a wide application prospect in the fields of functional foods, medicines, health care products and the like.
Owner:JIANGNAN UNIV

Lactobacillus crispatus capable of efficiently inhibiting alpha-glucosidase and application of lactobacillus crispatus

The invention discloses lactobacillus crispatus capable of efficiently inhibiting alpha-glucosidase and application of the lactobacillus crispatus. The lactobacillus crispatus JQH7 strain provided by the invention is separated and identified from human excrement, has relatively strong self-aggregation capability which can reach about 96% in 24 hours, can be better adhered to biological or non-biological surfaces, and is beneficial to effective colonization in an intestinal environment. Meanwhile, the JQH7 strain has certain antioxidant capacity, and the scavenging rate of a bacterial suspension of the JQH7 strain on DPPH free radicals is 49.18%; the JQH7 strain has the capability of efficiently inhibiting alpha-glucosidase, the effect of the JQH7 strain is equivalent to that of a clinical medicine acarbose, and compared with the acarbose, the JQH7 strain is safe in source, free of side effects, low in price, easy to obtain and easy to prepare. The invention provides more sources and choices for preparing preparations for efficiently inhibiting alpha-glucosidase and hypoglycemic products, provides a new thought for adjuvant therapy of diabetes, and is beneficial to improving and controlling the blood sugar of diabetics.
Owner:HUNAN CARE-U BIOTECHNOLOGY CO LTD

Minimally invasive flexible piezoelectric-triboelectric hybrid nanometer nerve stimulation device and application thereof

The invention discloses a minimally invasive flexible piezoelectric-triboelectric hybrid nanometer nerve stimulation device and application thereof.The middle layer of the nerve stimulation device is a PVDF / TMCM-MnCl3 composite nanofiber membrane, Au electrodes are evaporated on the two faces of the PVDF / TMCM-MnCl3 composite nanofiber membrane, two gold wire or copper wire electrodes are connected with the Au electrodes respectively, and the two gold wire or copper wire electrodes are connected with the Au electrodes respectively. The surface of the Au electrode is subjected to primary packaging by adopting a PU waterproof film, and the surface of the PU waterproof film is subjected to secondary packaging by adopting PDMS. The nerve stimulation device is used for conventional treatment of SIRS. The vagus nerve stimulator can generate an adjustable current up to 0.85 mA under programmable ultrasonic driving, and can be directly used for VNS. The PTNG is ultrasonically driven in vitro to assist the VNS in treating lipopolysaccharide-induced SIRS rats, release of inflammatory factors such as TNF-alpha, IFN-gamma and IL-1beta can be effectively reduced, cytokine storm is relieved, and multi-organ tissue damage and dysfunction are relieved, so that the survival hope is improved.
Owner:TONGJI HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI TECH

Application of bifidobacterium longum in improving immunity and preparing product for preventing, treating and / or adjunctively treating rhinitis

The invention belongs to the technical field of microorganisms, and particularly relates to application of bifidobacterium longum in improving immunity and preparing products for preventing, treating and / or assisting in treating rhinitis. The preservation number of the bifidobacterium longum is GDMCC No: 65969, and the bifidobacterium longum can reduce the levels of MDA and NO in serum of mice and improve the activity of SOD and CAT and the content of GSH so as to relieve oxidative stress injury; inflammatory cell infiltration of nasal mucosa is reduced, and lung tissue inflammatory mediator level and inflammation-related gene expression are reduced to inhibit inflammation; th1 / Th2 immune balance is regulated, Th2 type cytokines are reduced, Th1 type cytokines are increased, and the high-dosage effect is close to that of loratadine. The strain has a treatment effect on allergic rhinitis through multiple mechanisms, and a new choice is provided for treatment of the strain.
Owner:THANKCOME BIOLOGICAL SCI & TECH CO LTD

Application of BACE2 inhibitor and composition in preparation of medicine for treating arteriovenous fistula stenosis after renal failure

The invention belongs to the technical field of biological medicines, and particularly relates to application of a BACE2 inhibitor and a composition in preparation of a medicine for treating arteriovenous fistula stenosis after renal failure. The invention provides an application of a BACE2 inhibitor and a composition thereof in preparation of drugs for prevention, adjuvant therapy or treatment of arteriovenous fistula stenosis after renal failure. According to the medicine, by reducing the expression level of BACE2 and reducing the content of soluble sVEGFR3, construction of a lymphatic network on the surface of arteriovenous fistula after renal failure is promoted, inflammation infiltration is relieved or neointima production is relieved, and the effects of prevention, adjuvant therapy or treatment of arteriovenous fistula stenosis after renal failure are achieved. The BACE2 inhibitor composition provided by the invention is simple in preparation method, can play a role in slow release of the BACE2 inhibitor, and is an effective intervention means for preventing and treating arteriovenous fistula stenosis after renal failure.
Owner:ZHEJIANG UNIV +1

A breast auxiliary treatment positioning puncture device

The present invention provides a breast auxiliary treatment positioning puncture device, which belongs to the technical field of breast surgical treatment, and comprises a support seat and a puncture needle. An angle adjustment component is arranged on the outside of the support seat, and the angle adjustment component comprises a fixed seat. An electric push rod is fixedly connected to the front of the fixed seat, and a fixed frame is fixedly connected to the end of the electric push rod away from the fixed seat. The breast auxiliary treatment positioning puncture device can adjust the insertion depth of the puncture needle as required by setting a needle insertion adjustment component and using a baffle frame to cooperate with a limiting tube. When the clamping component is used to limit the deviation of the puncture needle, the movement of the baffle frame is limited by the cooperation of the fixed column and the positioning hole, so as to accurately control the puncture depth. By setting the angle adjustment component and providing a fine-tuning structure in the angle adjustment component, the coarse adjustment and fine-tuning of the puncture angle of the puncture needle can be realized, so as to improve the accuracy of the puncture angle of the puncture needle.
Owner:AFFILIATED HOSPITAL OF JINING MEDICAL UNIV

Multi-modal knowledge decomposition-based rectal cancer neoadjuvant therapy curative effect prediction method and system

The invention belongs to the technical field of medical data processing, and discloses a rectal cancer neoadjuvant therapy curative effect prediction method and system based on multi-modal knowledge decomposition. The invention provides a multi-modal data fusion algorithm based on multi-modal knowledge decomposition, which decomposes multi-modal data into a plurality of independent modal knowledge, and does not lose important inter-modal complementary information while reducing redundant information. According to the method, the unsupervised clustering algorithm and the supervised CNN algorithm are used at the same time, and compared with a traditional image selection method only using unsupervised random selection or based on information entropy, the interference of noise data on image screening can be reduced, so that representative enteroscope images and CT images can be selected.
Owner:UNIV OF ELECTRONICS SCI & TECH OF CHINA

Multi-mode biofeedback ear vagus nerve adaptive stimulation device and method

The invention relates to the technical field of medical instruments, in particular to a multi-mode biological feedback ear vagus nerve self-adaptive stimulation device and method.The device comprises a host, a stimulation electrode, a signal collection bracelet and an electroencephalogram collection module, and the host comprises core hardware configuration and a power management system; the signal acquisition bracelet comprises an ECG module, a PPG module, a GSR module, a six-axis acceleration sensor and the like. The ear vagus nerve stimulation parameter can be dynamically adjusted through real-time analysis of multi-mode data such as electrocardio, electroencephalogram, heart rate variability, respiration-heart rate synchronism and emotional state, personalized precise treatment is achieved, meanwhile, the wearing comfort and the durability of the device are improved, and the application range is wide. The traditional Chinese medicine composition can be used for auxiliary treatment of various diseases such as inflammatory bowel disease, epilepsy, chronic insomnia, depression, chronic pain, anxiety disorder, post-traumatic stress disorder and autonomic nerve dysfunction, and the functions of a nervous system are adjusted and the symptoms of a patient are improved by accurately stimulating the vagus nerve in the auricular concha area.
Owner:YANCHENG HOSPITAL OF TRADITIONAL CHINESE MEDICINE

Medicinal and edible beverage for adjuvant therapy of diabetes

The invention is applicable to the technical field of adjuvant therapy of diabetes mellitus, and provides a medicinal and edible beverage for adjuvant therapy of diabetes mellitus, which comprises the following components: astragalus extract, kudzu vine root extract, corn stigma extract, ginseng extract, momordica grosvenori sugar substitute concentrated juice and hydrogen. The hydrogen is dissolved in the beverage; preferably, the radix astragali extract is radix astragali polysaccharide, the radix puerariae extract is radix puerariae flavone, the corn stigma extract is corn stigma peptide, and the ginseng extract is ginsenoside. According to the present invention, the effective component extracts, the targeted extracts and the hydrogen additive are adopted, such that the blood sugar can be effectively prevented and controlled, the significant treatment effect on the diabetes mellitus can be provided, and the prepared food-grade beverage can be used for a long time without any side effect on the human body.
Owner:HUNAN MAXSEE BIOTECHNOLOGY CO LTD

Precise nutritional composition for improving cognitive function

The invention provides a composition. The composition consists of spirulina, astaxanthin, vitamin C and health food or food acceptable auxiliary materials. The composition has the advantages that the composition has a synergistic effect, and can effectively relieve cognitive impairment of a tested object and improve learning and memory functions, so that the composition can be used for preventing or adjunctively treating the Alzheimer's disease and can also be used for precise nutritional supplement of specific people. In addition, the multi-component compound form of the product can obviously improve the taking compliance of users, and the total use cost is saved.
Owner:SHENZHEN AUSA PHARMA +2

A cervical spine assisted treatment device for pain department nursing

The present invention discloses a cervical spine auxiliary treatment device for pain department nursing, which relates to the technical field of medical auxiliary instruments and includes: a main body mechanism, on one side of the inner wall of the main body mechanism, an auxiliary treatment mechanism is fixedly installed, the auxiliary treatment mechanism includes a nursing frame, an internal motor is fixedly inserted inside the nursing frame, the rotating end of the internal motor is fixedly connected to a threaded rod, and two internal gears are thread-driven on the outer surface wall of the threaded rod. In the present invention, through the coordinated work within the rotation speed control component, the rotation speed of the internal motor can be precisely controlled, and then the motion states of the massage roller and the staggered extrusion roller can be accurately adjusted. It can flexibly adjust parameters such as treatment intensity and frequency according to the conditions and needs of different patients, meet the personalized treatment requirements, not only improve the treatment effect, but also can adjust the treatment according to the conditions of different patients, improve the adaptability of the device, and avoid the problem of secondary injury to patients caused by inaccurate adjustment.
Owner:CHENGDU MILITARY GENERAL HOSPITAL OF PLA

Local advanced rectal cancer neoadjuvant therapy curative effect prediction system based on AI

The invention relates to the technical field of rectal cancer, and discloses an AI-based local advanced rectal cancer neoadjuvant therapy curative effect prediction system, which comprises a data collection and processing module, a prediction model construction and training module, a prediction model verification and optimization module and a clinical application module, the data collecting and processing module is used for collecting clinical data, image data, radiotherapy target area data, radiotherapy dose data, radiobiology data and genomics data of a patient and then transmitting the data to the prediction model building and training module, and the prediction model building and training module extracts and selects key features in the data. And constructing a tumor segmentation multi-modal fusion and calibration network prediction model based on the PET / CT image. According to the invention, the data of the patient is collected through the data collection and processing module, so that the accuracy of radiotherapy effect and side reaction prediction is improved through the constructed prediction model, and the problem of feature capture limitation caused by a single center and a single mode of an existing AI model is solved.
Owner:CHINESE PEOPLES LIBERATION ARMY ARMY SPECIAL MEDICAL CENTER

Application of cynarin as cGAS-STING signaling pathway inhibitor in preparation of anti-inflammatory drugs

The invention belongs to the technical field of biological medicine, and particularly relates to application of cynarin as a cGAS-STING signal channel inhibitor in preparation of anti-inflammatory drugs. It is found for the first time that cynarin can inhibit phosphorylation of STING and translocation of STING by influencing the stability of STING spatial conformation, so that channel downstream protein activation is inhibited, nuclear translocation of IRF3 is hindered, expression of a series of interferon-induced related genes such as IFN-beta, CXCL10 and ISG15 is inhibited, finally secretion of IFN-beta can be hindered, cGAS-STING inflammatory response can be inhibited by targeting STING, and the application of cynarin in inhibiting cGAS-STING inflammatory response is achieved. A new thought and a new means are provided for developing an auxiliary treatment method aiming at STING related inflammations.
Owner:GUANGZHOU MEDICAL UNIV