35 results about "Biowarfare Agents" patented technology

The invention provides a soil pollution intelligent monitoring and early warning method based on coupling of source accurate prevention and control and enhanced natural restoration, and relates to the technical field of pollution hidden danger investigation and source tracing. According to the method, toxic and harmful substances are identified through data collection, interview and reconnaissance, a key monitoring list is constructed, troubleshooting and leakage detection are carried out, hidden danger judgment and grading are completed, a rectification strategy is matched to generate a bioremediation scheme, biological agent injection or biological pile construction is carried out on a remediation area, and remediation effect evaluation is carried out. And setting monitoring factors and arranging monitoring point positions after the restoration reaches the standard, collecting monitoring data and inputting the monitoring data into a monitoring and early warning system, and realizing abnormal alarm through threshold triggering. According to the method, a closed-loop process from source identification, restoration implementation to long-term monitoring is constructed, and the accuracy and early warning efficiency of pollution treatment are improved.

The invention relates to a biological agent, in particular to a preparation method of the biological agent, which comprises the following steps: S1, injecting a cultured biological bacterium culture solution into a centrifugal space formed by a plurality of separation rings and a plurality of separation cavities; s2, a plurality of separation rings and a plurality of separation cavities are driven to rotate, and a plurality of water spraying holes spray liquid from top to top to impact the biological bacteria; s3, the biological bacteria with large mass are left on the lower side, and the biological bacteria with small mass are flushed to the upper side by the liquid; s4, after the biological bacteria are separated according to the mass, a plurality of separation rings rotate to discharge the liquid; s5, the biological bacteria are left in the centrifugal space; s6, pressure gas is introduced into a plurality of separation cavities, and an elastic inclined plate is inclined and expands to separate the biological bacteria according to the mass; and the biological bacteria can be centrifugally classified according to different masses.

This invention belongs to the field of biological control technology for agricultural pests. Specifically, this invention relates to a gene that regulates the growth and development of the common thrips and its application. Through extensive research, this invention discovered a key gene, Mu10, that regulates the growth and development of the common thrips (Megalurothrips usitatus Bagnall). Based on this, an interference fragment and dsRNA targeting the Mu10 gene were obtained. A method for targeting and regulating the Mu10 gene and a corresponding biological agent were established. Results show that the method and agent of this invention can inhibit the growth and development of the common thrips and significantly reduce its survival rate, providing new ideas and technical support for inhibiting the growth and development of the common thrips and solving its pesticide resistance problem.

The application discloses a biological agent storage device which comprises a storage outer box, a test tube placing rack and a cleaning assembly, the storage outer box comprises an outer box body, a box cover and an inner box, the top end of the outer box body is provided with an opening, the box cover is rotationally arranged at the opening end of the outer box body, the inner box is arranged in the outer box body, the test tube placing rack and the cleaning assembly are arranged in the inner box, the cleaning assembly comprises a cleaning ring and a cleaning rubber strip, the cleaning ring is horizontally arranged in the inner box, the cleaning rubber strip is arranged on the outer ring wall of the cleaning ring, and the cleaning rubber strip is arranged in close contact with the inner wall of the inner box. The application has the effect of realizing stable storage of biological agents.

1. The name of the design product: fungus cube. 2. The use of the design product: for the storage and release of biological agents in the environment of ornamental fish, ensuring the safe and convenient use of the agents and maintaining the health of the water body. 3. The design points of the design product: the combination of shape and pattern. 4. The picture or photo that best shows the design points: perspective view.

This invention relates to the field of bio-infectious agent metabolites, and discloses a bio-infectious agent metabolite for the safe improvement of agricultural products and its preparation method. The bio-infectious agent metabolite is obtained by fermenting a fermentation raw material composed of a carbon source and a nitrogen source with an immobilized composite microbial agent on an organic-inorganic composite carrier. The organic-inorganic composite carrier immobilized composite microbial agent is prepared by immobilizing the composite microbial agent onto a chitosan-sodium alginate organic embedding carrier and an inorganic adsorbent carrier using immobilization loading technology. The composite microbial agent consists of *Bacillus circinus*, *Bacillus licheniformis*, *Bacillus amyloliquefaciens*, and *Bacillus subtilis*. This invention provides a method for preparing bio-infectious agent metabolites, and yields a bio-infectious agent metabolite containing carbohydrate compounds, amino acid compounds, organic acid compounds, and plant hormones, which has a quality-improving effect on agricultural products.

The application discloses an application of a nuclear receptor target gene in preparation of a biological preparation for blocking activation of diapause larvae, and relates to the field of biotechnology and parasite prevention and control. According to two nuclear receptor targets of Haemonchus contortus HCON_00101910 (regulating activity of worms) and HCON_00023750 (regulating development of larvae), the two nuclear receptor targets are combined with host progesterone and estradiol and are activated, constitute a key signal path in the spring activation process of diapause larvae, and have no homologous genes in mammals, and the safety is excellent. By constructing specific shRNA lentivirus vectors (the silencing efficiency is all greater than or equal to 60%) targeting the two genes, single target or double target synergistic intervention is realized, and the activity-development double key links of worms in the host body can be specifically blocked. The application provides a new paradigm of preventive prevention and control with high specificity and green safety, and provides core technical support for solving the seasonal epidemic problem of blood fluke disease.

Provided herein is an automation device for identifying and collecting biological agents, which improves user convenience and enhances operational efficiency by integrating the collection and identification processes. The automation device includes: a collection unit including a movable filter tray; and an identification unit disposed apart from the collection unit and configured to wash and store collected biological agents, where a filter assembly may be mounted on the filter tray, the filter assembly being configured to collect biological agents by passing external air through a filter, and the filter coupled inside the filter assembly may be configured to automatically rotate as the filter tray moves to the identification.

In various examples, the subject matter of this disclosure relates to developing and using machine learning models to predict biological activity profiles based on multimodal datasets. An example method of predicting biological activity profiles includes: providing a multimodal dataset comprising a plurality of distinct dataset modalities (including at least one chemical structure dataset) to a foundation model, training a foundation model by applying contrastive learning to the multimodal dataset, creating a learned representation of each dataset modality, training a predictive model based on the learned representation of the chemical structure dataset modality and a classifier function that assigns modulation status for the biological target, and introducing an agent to the predictive model to predict modulation of the biological target.

The utility model provides a biological agent feeding device for repairing organic contaminated soil, which belongs to the technical field of microbial strains and comprises a base, a push handle is fixedly arranged at the leftmost end of the base, a liquid storage tank and an intelligent controller are fixedly mounted on one side, close to the push handle, of the upper surface of the base, and a stirring device is arranged at the center of the top of the liquid storage tank; a through groove is formed in the upper surface, away from the push handle, of the base, a baffle is fixedly installed in the through groove and divides the through groove into a pesticide spraying groove and a soil turning groove, a pesticide storage box is arranged on the left edge of the pesticide spraying groove, and a sprinkler head is fixedly installed on the outer side face of the pesticide storage box; a rotating shaft is mounted in the soil turning groove, and soil turning plow claws are uniformly and annularly mounted on the rotating shaft; the other end of the rotating shaft penetrates through the inner wall of the through groove to be connected with the output end of a second motor, and the second motor is connected with an intelligent controller through an electric wire. The soil plowing and biological agent feeding device integrates the functions of soil plowing and biological agent feeding, time and labor cost are saved, the soil plowing and biological agent feeding device is suitable for large-area soil remediation, and working efficiency is improved.

The invention relates to the technical field of pest control equipment, and discloses a forest nursery stock pest biological agent spraying device which solves the problem that the spraying effect of a biological agent is poor due to the fact that the angle of an existing spray head is mostly fixed, the forest nursery stock pest biological agent spraying device comprises a base, and a plurality of universal wheels are arranged at the bottom of the base at equal angles; a liquid storage tank and a push rod are fixedly mounted at the top of the base, a liquid inlet pipe is fixedly connected to the top of the liquid storage tank, an angle adjusting mechanism and a lifting mechanism are arranged on the outer side of the liquid storage tank, a power mechanism is arranged at the top of the base, the angle adjusting mechanism comprises a mounting plate located on the outer side of the liquid storage tank, and a U-shaped frame is fixedly connected to the side, away from the liquid storage tank, of the mounting plate; the inner side of the U-shaped frame is rotationally connected with a first inner shaft, and the outer side of the first inner shaft is fixedly sleeved with a first support. According to the device, the inclination angle of each nozzle II can be conveniently changed, so that the angles of the nozzle I and the nozzle II can be conveniently adjusted according to requirements to improve the spraying effect of the biological agent.

The present invention relates to a device for receiving and processing cartridges for releasing biological agents, developed to integrate efficiently with the cartridges already known in the prior art, improving the handling, operation, and implementation thereof, wherein the device comprises integrated mechanisms for loading and aligning the cartridges, activation systems for releasing the contents thereof, and, optionally, a control system configured for manual, semi-automatic, or automatic operation.

Infectious diseases have been sources of large-scale epidemics and pandemics resulting in millions of casualties worldwide. Detection of these biological agents normally involves several lab processes including sample preparation, nucleic acid separation and amplification, and diagnostic analysis. These steps, either performed manually or automated by high-throughput machinery, are tedious, expensive, and highly susceptible to cross-contamination. The present system is an integrated lab-on-a-device designed, developed, and tested in compatibility with a mechanical fixture for sample-to-answer biological analysis of infectious diseases.

This invention discloses a liquid temperature-controlled system for phage preparations, belonging to the field of biological agent storage and transportation. The liquid temperature-controlled system for phage preparations includes a housing, a temperature regulation unit, an energy storage and power supply unit, a solar power generation unit, an environmental sensing unit, an intelligent control unit, and a monitoring, control, and data acquisition unit. This invention solves the problems of existing temperature-controlled storage equipment relying on mains power, insufficient energy management efficiency, and susceptibility to failure due to energy depletion in outdoor or unstable power environments. Through solar self-powering and intelligent energy prediction management, this invention enables long-term self-sustaining operation of the system in complex environments. Furthermore, by employing a multi-mode switching and adaptive temperature control strategy based on energy prediction, it can improve the system's environmental adaptability and energy utilization efficiency while ensuring the core temperature requirement for phage preparation activity.

1. Name of the product in this design: Biological Agent Storage Rack. 2. Purpose of this design: This design is for the temporary storage of biological agents. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: 3D view 1.

Method and system for the demilitarization of conventional ammunition of all types and calibers as well as chemical and biological weapons in which takes place the automated detection of each type via an Artificial Intelligence (AI) system, their instantaneous destruction and the immediate separation of the chemical-biological agent, the explosive material and the metallic mass within a co-rotating pulsed vortex environment under controlled electromagnetic field, which is applied by entering into a specialized feeding apparatus (1), a bipolar rotational vortex chamber (2), a metal parts separator (3), a metal mass processing unit (4), a configured annular drainage and separation apparatus (5), an electric arc unit (6), an off gases treatment unit originating from the electric arc unit, a gaseous pollutants treatment unit (8), a closed-loop type A and B emulsion supply-recycling system and a emulsion treatment system via E / M pulse application (111), while the whole operation is controlled by a control and operation unit (9).

The application discloses a non-toxic genetically engineered toxoid molecule antigen vaccine based on a protective antigen functional domain structure and a preparation method and application thereof. It is determined that botulinum toxin and tetanus toxin both have two key protective antigen molecules, i.e. a receptor binding region Hc and a light chain-transmembrane region L-HN. Based on the important role of the functional domain in immunoprotective efficacy, a non-toxic genetically engineered toxoid or chimeric toxoid multivalent vaccine molecule is designed and prepared by using a biosynthesis technology. The vaccine has two important protective antigens of biological toxins, can produce strong complete protection at a low dose and a small number of immunization times, and can be used as a high-efficiency genetically engineered toxoid vaccine to replace formaldehyde inactivated toxoids for biological toxin prevention. The vaccine has important protective antigens of two different biological toxins, can produce protective efficacy against a plurality of different toxin biological agents, and can be used as a broad-spectrum multivalent vaccine for biological toxin prevention.

The disclosure provides microbial signalers that increase the plant growth-promoting function of target microbes present in commercial biological agents. The plant-growth promoting functions may include plant pathogen inhibiting functions, zinc solubilizing functions, or phosphate solubilizing functions. The disclosure further relates to compositions, comprising: the microbial signalers, and to methods of using the compositions to produce improved soil for plant growth.

The application provides a low-permeability contaminated stratum fracturing and biodegradation remediation system and method, and the remediation system comprises a casing, a hydraulic fracturing device, a biological agent injection device, a cross resistivity monitoring device, a pH driving device, a thermal resistance driving device and an online monitoring and control system, wherein the hydraulic fracturing device is used for manufacturing cracks in the soil to provide a channel for biological agent delivery; the biological agent injection device is used for delivering the biological agent to the contaminated soil through the cracks; the cross resistivity monitoring device is used for monitoring resistivity changes in real time to adjust the injection amount and injection process of the biological agent; the pH driving device and the thermal resistance driving device are used for changing the soil pH and temperature, respectively; and the online monitoring and control system is connected with the above five devices to monitor and control the operation of the whole remediation system. The application has the advantages of simple process, environmental friendliness, low cost, good remediation effect, accurate and rapid remediation and large-scale remediation.

1. Name of the product in this design: Integrated Nuclear, Biological and Chemical System. 2. Purpose of this design: For the detection of nuclear radiation, chemical agents, and biological agents. 3. The key design features of this product are the combination of shape and pattern. 4. The image or photograph that best illustrates the design's key points: a 3D model.

The present technology provides a threshold sensing device including an inductor, a ferroelectric varactor, and a resonator sensitive to a selected parameter of interest. The unbiased varactor has a memory window that grows proportionally with the partial switching of the varactor's ferroelectric domains. A DC voltage is generated across the varactor which, above a parameter threshold sensed by the resonator, drives the ferroelectric switching of the varactor. A nonvolatile shift in a radio frequency readout signal serves as a memory of an exceeded parameter threshold detected by the resonator. The sensor device can be used to detect temperature violations in a cold chain or the presence of a chemical or biological agent and is capable of battery-less operation.

The invention relates to the technical field of biological medicine sub-packaging equipment, in particular to a biological preparation sub-packaging device. Comprising a supporting table, a position adjusting mechanism is arranged on the supporting table, a containing frame used for containing medicament bottles is arranged on the position adjusting mechanism, the position adjusting mechanism is used for adjusting the position of the containing frame, a first motor is installed on the supporting table, and a rotating table is connected to an output shaft of the first motor. Through the design of the rotary table, after one biological agent is subpackaged, the storage and subpackaging assemblies on the two sides can be shifted by rotating by 180 degrees and switched to the other side to continue subpackaging the other biological agent, shutdown for cleaning is not needed, the continuous operation capacity and production efficiency of the device are remarkably improved, the device is provided with a cleaning system, and the cleaning efficiency is improved. When one biological agent is subpackaged, the storage frame, the input pipe, the output pipe and the positioning pipe on the other side can be automatically cleaned, residues are effectively removed, cross contamination is avoided, and the manual cleaning strength is reduced.

1. Name of the product in this design: Biological Detection Box. 2. Purpose of this design: for the detection and storage of biological agents. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: a 3D model.

The application relates to the field of agricultural pest control, in particular to a facility tomato pest control device and method, which discloses a facility tomato pest control device and method, and aims to solve the technical problem of low survival rate and colonization rate of natural enemy insects in existing biological control technology due to unsuitable facility environment conditions. The device comprises: an environment sensing module for collecting environment parameter data in a facility greenhouse in real time; a main control unit for receiving and processing the environment parameter data and generating a control decision; a microclimate regulation subsystem for forming a local suitable microenvironment area in the facility greenhouse; a multi-stage intelligent release subsystem for accurately releasing natural enemy insects or biological agents to key positions of plant canopies; an air flow regulation subsystem for optimizing air flow field distribution to promote active diffusion of the natural enemy insects; and a pest dynamic tracking module for real-time monitoring and prediction of pest occurrence dynamics. Through the synergistic effect of the above technical solutions, the survival rate and colonization rate of the natural enemy insects can be significantly improved, the control effect is stable and controllable, and technical support is provided for green and safe production of the facility tomatoes.

The utility model discloses a biological preparation ultrafiltration device convenient to clean, which comprises an ultrafiltration cylinder, a backwashing assembly, an ultrafiltration assembly and a top cover, the backwashing assembly comprises a washing pipe arranged on the ultrafiltration cylinder, a vertical pipe arranged on the right side of the washing pipe and a connecting pipe arranged on the right side of the vertical pipe, the ultrafiltration assembly comprises an ultrafiltration membrane inserted in the ultrafiltration cylinder in a penetrating manner, a mounting seat arranged at the top of the ultrafiltration membrane, a liquid inlet pipe arranged at the top of the mounting seat and a handle arranged on the liquid inlet pipe, and the top cover is rotationally connected with the mounting seat through a bearing and is in threaded connection with the top of the ultrafiltration cylinder; and the top cover is in threaded connection with an adjusting rod. According to the utility model, the backwashing assembly, the ultrafiltration assembly and the top cover are arranged, so that under the condition that the ultrafiltration device is not disassembled for use, the effect of convenient cleaning is realized, time and labor are saved, and meanwhile, the sealing assembly is arranged, so that the leakage-proof effect is realized, and the use is convenient.

The utility model relates to the technical field of filtering devices, in particular to a filtering device for biological agents, which comprises a filtering box shell and a sealing cover, a sealing structure is arranged on the edge of the sealing cover, the sealing cover is fixedly connected to the upper end of a filtering barrel through the sealing structure, and after the sealing cover and the filtering barrel are connected in a buckled mode, a first sealing ring is extruded to achieve the sealing effect. A filtering structure is arranged at the lower end of the sealing cover, the lower end of the filtering structure is inserted into the upper end of the filtering barrel, the filtering structure is lower than the horizontal height of the overflow opening, an exhaust structure is arranged in the middle of the filtering structure, and the upper end of the exhaust structure communicates with the outside; the filter box has the beneficial effects that the filter box shell, the sealing cover and the filter barrel are connected into a whole through fence plate buckle connection and bolt close fit, meanwhile, replacement and cleaning are convenient, when liquid enters the filter box shell, the sealing cover and the filter barrel, precipitation and recycling work is completed through the double-layer cavity, then the purpose of re-filtering is achieved through the three filter adsorption layers, and the integrated filter function is achieved.

The utility model discloses a biological medicament extraction device, including extraction container main part, press-down subassembly, extraction container main part top thread connection is equipped with the top cover, press-down subassembly includes fixed block, motor no. 1, sawtooth batten, fixed block lower surface and top cover middle part upper surface installation, motor no. The output end of the first motor is fixedly sleeved with a gear, the outer edge of a sawtooth strip plate is slidably mounted on the inner edge of the middle of the fixing block and slidably mounted on the inner surface of the middle of the top cover, the sawtooth strip plate is meshed with the gear, and a double-layer pressing filter plate is fixedly mounted at the bottom end of the sawtooth strip plate. The outer edge of the double-layer pressing filter plate is movably sleeved with the inner edge of the extraction container main body, and an auxiliary mixing assembly is arranged at the top of the double-layer pressing filter plate; by means of the downward pressing assembly, the plant components go deep into the extraction solvent, the contact effect of the plant components and the extraction solvent is improved, and then the extraction effect of the plant biological agent is improved.

This utility model relates to the technical field of biomedical engineering and discloses a gradient dilution positioning rack for biological agents. It includes a chassis, a rotating shaft fixedly connected to the top center of the chassis, a protective mechanism at the top of the rotating shaft, and a limiting shell fixedly connected to the top of the chassis. A heating component is provided on the inner wall of the limiting shell. The protective mechanism includes a chuck, the bottom of which is fixedly connected to the top of the rotating shaft, and multiple fixing slots on the top of the chuck. In this utility model, the valve cap closes naturally to prevent liquid leakage; the anti-contamination plate isolates adjacent test tubes, reducing cross-contamination; and the protective cap, after rotating and closing, forms a closed space with the chuck, which, combined with the cleaning component, allows for further cleaning. This effectively prevents liquid leakage and aerosol diffusion, solving the problem of contamination prevention that existing technologies cannot achieve, and improving the safety and reliability of sample processing.

The utility model discloses a proportioning device for an insecticidal and degerming biological agent, which relates to the technical field of proportioning devices and comprises a box body, a motor and a mixing shaft, the mixing shaft is rotatably and obliquely arranged on the box body, an output shaft of the motor is connected with a driving gear, and the mixing shaft is fixedly connected with a driven gear meshed with the driving gear; according to the utility model, the unique revolution and rotation combined motion mode of the mixing shaft enables the mixing blades to stir raw materials in all directions and at multiple angles, so that the innovative design greatly improves the mixing uniformity, and ensures that the raw materials with different densities, particle sizes and properties in biological agents are in full contact and are uniformly mixed; the accuracy and the stability of the preparation ratio are powerfully guaranteed, and the product quality is further improved.