133 results about "Biowarfare Agents" patented technology

The invention belongs to the technical field of environment, and particularly relates to an environment-friendly biological agent for repairing and treating petroleum polluted water and soil and a preparation method of the environment-friendly biological agent. The biological agent is prepared by mixing a compound microbial agent, a biological surfactant and an auxiliary material in parts by mass, has the characteristics of high efficiency, environment friendliness and no secondary pollution, can remarkably improve the remediation efficiency of petroleum-contaminated soil, and has a wide application prospect.

The invention provides a soil pollution intelligent monitoring and early warning method based on coupling of source accurate prevention and control and enhanced natural restoration, and relates to the technical field of pollution hidden danger investigation and source tracing. According to the method, toxic and harmful substances are identified through data collection, interview and reconnaissance, a key monitoring list is constructed, troubleshooting and leakage detection are carried out, hidden danger judgment and grading are completed, a rectification strategy is matched to generate a bioremediation scheme, biological agent injection or biological pile construction is carried out on a remediation area, and remediation effect evaluation is carried out. And setting monitoring factors and arranging monitoring point positions after the restoration reaches the standard, collecting monitoring data and inputting the monitoring data into a monitoring and early warning system, and realizing abnormal alarm through threshold triggering. According to the method, a closed-loop process from source identification, restoration implementation to long-term monitoring is constructed, and the accuracy and early warning efficiency of pollution treatment are improved.

The present disclosure provides for devices and systems for detecting biological agents (e.g., virus such as coronavirus) using nanotriangles having a capture agent. The present disclosure also includes methods of detecting the presence and amount of the biological agent in a sample, such as saliva, blood, or urine. In addition, the present disclosure provides for a detecting module and a method of making the detecting module, where the detecting module includes the nanotriangles having the capture agent bonded thereto that has an affinity for the biological agent.

The invention discloses a prevention and control method for tobacco soil-borne diseases based on a mushroom waste substrate and application. Belongs to the technical field of tobacco soil-borne disease prevention and control. According to the method, the tobacco soil-borne diseases are prevented and controlled by combining the mushroom waste substrate with the biological agent, the added mushroom waste substrate can increase the antibacterial activity of biocontrol bacteria, the control effect of the biocontrol bacteria is remarkably improved, the application direction of the mushroom waste substrate is widened, and maximum utilization of mushroom waste substrate resources is achieved on the premise of environment friendliness.

The invention discloses a method for preventing dsRNA bacterial liquid from being degraded by ultraviolet, a biological preparation for preventing and controlling bemisia tabaci and a prevention and control method, and belongs to the technical field of pest prevention and control. The method for preventing the dsRNA bacterial liquid from being degraded by ultraviolet comprises the following steps: mixing the dsRNA bacterial liquid with a UV protective agent to prepare a mixed solution of the UV protective agent and the dsRNA bacterial liquid; the UV protective agent is one of potassium humate and sodium humate. The UV protective agent provided by the invention can effectively avoid degradation of dsRNA bacterial liquid, so that the dsGawky can give full play to the fatal effect on bemisia tabaci, and the target of pest control is accurately achieved. The method is efficient, wide in application, easy to formulate, high in insecticidal efficiency and environment-friendly, has the advantages of promoting plant growth and the like, and has a very good application prospect.

A portable, automated, single-use filter cart system for continuous or batch replaceable biologics production processes is disclosed.

The invention relates to the technical field of biological function prediction, in particular to a biological reagent function prediction method and system. The method comprises the following steps: carrying out biomolecule information acquisition on a biological reagent public database to obtain a biological reagent biomolecule information set; performing biological characteristic analysis on the biological reagent biomolecule information set to obtain biological reagent protein sequence comparison characteristics, biological reagent molecular structure domain characteristics and biological reagent specific molecular function domain characteristics; constructing a biological reagent function prediction network framework and performing function prediction model training construction to generate a biological reagent function prediction model; obtaining molecular characteristics of the biological reagent to be predicted and performing target function prediction to obtain a target biological reagent function prediction result; and performing function verification optimization according to the target biological reagent function prediction result to generate a target biological reagent function optimization result. According to the invention, effective pre-judgment and screening of biological reagent functions can be realized.

The invention provides bacillus velezensis BVDT-1 and application thereof, and belongs to the technical field of biological agents. The bacillus velezensis BVDT-1 strain is obtained through separation and identification, has an inhibition effect on various plant pathogenic fungi such as waxberry wilting germs, persimmon colletotrichum gloeosporioides and persimmon leaf spot germs, provides a new resource for biological prevention and control of related fruit tree diseases, and compared with part of similar strains, the bacillus velezensis BVDT-1 strain has the advantages that the antibacterial effect of the plant pathogenic fungi is not mentioned, and the bacillus velezensis BVDT-1 strain has a good application prospect. The strain is excellent in genome characteristic, high in degradation capacity, low in drug-resistant gene risk and large in secondary metabolite synthesis potential, can secrete unknown antibiotics possibly, provides powerful support for application in the fields of biological control and microbial fertilizer, and has wide application prospects in the aspects of biological control, agricultural production and the like.

The invention provides a multi-temperature-zone intelligent regulation and control medical cold chain system aiming at the problems of differentiated temperature requirements and biological safety in medicine cold chain transportation. The system is based on a multi-stage semiconductor refrigeration technology and a PCMS composite thermal insulation structure, a plurality of temperature zones which can be independently managed are arranged in the same box body, and a multi-source sensor array and an improved thermal coupling equation are combined; partitioned temperature fine control and cooperative energy consumption management are carried out on biological agents (such as vaccines, plasma and pathogen specimens) with different sensitivities and storage and transportation requirements. Layered energy storage and energy release are carried out in multiple temperature intervals through the phase change materials, self-adaptive compensation is carried out on factors such as box vibration, inclination and environment sudden change through a main control algorithm, and the medicine failure risk caused by temperature chain scission and overshoot is remarkably reduced. On the basis, the invention also provides a cloud big data analysis and remote scheduling mechanism, information such as real-time temperature curves, energy consumption indexes and pre-estimated residual cooling capacity of multiple temperature zones can be synchronously uploaded, potential faults and route congestion are automatically identified by means of a distributed algorithm, and then an energy-saving or emergency cooling instruction is issued to the box body. For extreme cryogenic requirements and high-risk pathogen scenes, the stability and the isolation protection level of a cryogenic area can be enhanced through the additional refrigerant circulating unit and the biological safety isolation cabin, and it is ensured that stable low temperature and high safety can still be kept in long-time cross-regional transportation.

The invention belongs to the technical field of plant protection and biological prevention and control, and particularly relates to a biological preparation for efficiently preventing and controlling red spiders. The biological agent for efficiently preventing and controlling red spiders, provided by the invention, is prepared from the following raw materials in parts by mass: 5 to 10 parts of lactic acid, 10 to 15 parts of ethanol, 8 to 15 parts of chitosan, 12 to 25 parts of marigold extract, 3 to 8 parts of clove extract, 1 to 3 parts of cationic surface active agent, 1 to 3 parts of VC and 30 to 60 parts of deionized water. The invention has a triple action mechanism of charge repulsion, biological inhibition and physical plugging, and can efficiently prevent and control red spider pests.

The invention relates to a biological agent, in particular to a preparation method of the biological agent, which comprises the following steps: S1, injecting a cultured biological bacterium culture solution into a centrifugal space formed by a plurality of separation rings and a plurality of separation cavities; s2, a plurality of separation rings and a plurality of separation cavities are driven to rotate, and a plurality of water spraying holes spray liquid from top to top to impact the biological bacteria; s3, the biological bacteria with large mass are left on the lower side, and the biological bacteria with small mass are flushed to the upper side by the liquid; s4, after the biological bacteria are separated according to the mass, a plurality of separation rings rotate to discharge the liquid; s5, the biological bacteria are left in the centrifugal space; s6, pressure gas is introduced into a plurality of separation cavities, and an elastic inclined plate is inclined and expands to separate the biological bacteria according to the mass; and the biological bacteria can be centrifugally classified according to different masses.

A biological agent releasing receptacle for releasing a biological agent in proximity of vegetation to be treated is provided. The biological agent releasing receptacle includes an elongated body with a receptacle wall defining a receptacle cavity configured to receive the biological agent therein. The elongated body includes a soil-contacting portion configured to be inserted into soil and a biological agent releasing portion located opposite the soil-contacting portion and configured to extend outwardly from the soil, away from the soil-contacting portion. One or more biological agent releasing opening is defined in the receptacle wall of the biological agent releasing portion to release the biological agent received in the receptacle cavity in proximity of the vegetation to be treated. Methods for preparing the biological agent releasing receptacle, as well as methods for installing the biological agent releasing receptacle, for instance in a crop, are also provided.

The invention discloses a microcapsule for preventing dsRNA bacterial liquid from being degraded by ultraviolet, a biological preparation for preventing and controlling bemisia tabaci and a method for preventing and controlling the bemisia tabaci, and belongs to the technical field of pest prevention and control. The invention discloses a microcapsule for preventing dsRNA (double-stranded ribonucleic acid) bacterial liquid from being degraded by ultraviolet. The dsRNA bacterial liquid is embedded into the microcapsule by adopting dopamine or dopamine and chitosan. The dsRNA bacterial liquid microencapsulation can effectively prevent the degradation of the dsRNA bacterial liquid, so that the dsGawky can give full play to the fatal effect on bemisia tabaci, and the target of pest prevention and control is accurately achieved. The invention has the advantages of controlled release, improvement of targeting and drug stability, wide application, high insecticidal efficiency, environmental friendliness and the like, and has a good application prospect.

This invention belongs to the field of biological control technology for agricultural pests. Specifically, this invention relates to a gene that regulates the growth and development of the common thrips and its application. Through extensive research, this invention discovered a key gene, Mu10, that regulates the growth and development of the common thrips (Megalurothrips usitatus Bagnall). Based on this, an interference fragment and dsRNA targeting the Mu10 gene were obtained. A method for targeting and regulating the Mu10 gene and a corresponding biological agent were established. Results show that the method and agent of this invention can inhibit the growth and development of the common thrips and significantly reduce its survival rate, providing new ideas and technical support for inhibiting the growth and development of the common thrips and solving its pesticide resistance problem.

The application discloses a biological agent storage device which comprises a storage outer box, a test tube placing rack and a cleaning assembly, the storage outer box comprises an outer box body, a box cover and an inner box, the top end of the outer box body is provided with an opening, the box cover is rotationally arranged at the opening end of the outer box body, the inner box is arranged in the outer box body, the test tube placing rack and the cleaning assembly are arranged in the inner box, the cleaning assembly comprises a cleaning ring and a cleaning rubber strip, the cleaning ring is horizontally arranged in the inner box, the cleaning rubber strip is arranged on the outer ring wall of the cleaning ring, and the cleaning rubber strip is arranged in close contact with the inner wall of the inner box. The application has the effect of realizing stable storage of biological agents.

1. The name of the design product: fungus cube. 2. The use of the design product: for the storage and release of biological agents in the environment of ornamental fish, ensuring the safe and convenient use of the agents and maintaining the health of the water body. 3. The design points of the design product: the combination of shape and pattern. 4. The picture or photo that best shows the design points: perspective view.

The utility model relates to the technical field of circulating water quality detection devices, and particularly discloses an industrial circulating water simulation device for testing the scale and corrosion inhibition performance of a biological agent. The heating assembly can heat the circulating cooling water in the first water tank; a to-be-detected pipeline quick connector is sleeved in the water supply pipe; the spraying assembly is communicated with one end of the water supply pipe fitting and is used for spraying circulating cooling water into the first water tank; a water inlet of the delivery pump is communicated with the first water tank, and a water outlet of the delivery pump is communicated with one end, away from the spraying assembly, of the water supply pipe; the hanging piece assembly is provided with a plurality of metal pieces, and the metal pieces are located below the water outlet of the spraying assembly; and the biological membrane frame is filled with a bacteria-containing carrier, is immersed in the first water tank, and can simulate different production environments and test the scale and corrosion inhibition performance of the biological agent.

The utility model discloses a biological agent full-automatic hard capsule filling machine which comprises a capsule filling machine and a blast purging mechanism, the capsule filling machine comprises a machine body, a capsule sowing mechanism and a filling mechanism, and the capsule sowing mechanism and the filling mechanism are arranged in the machine body; the air guiding hose is connected with the air exhaust end of the air blower and penetrates into the machine body, the transverse pipe is connected with the end, located in the machine body, of the air guiding hose, and a plurality of air nozzles are installed on the surface of the side, away from the air guiding hose, of the transverse pipe. On the basis of the full-automatic hard capsule filling machine, the air blowing purging mechanism is arranged in the filling cabin area of the machine body, external air is filtered by the filter plate and the air filter element through the air blower and then is discharged into the air nozzle on the transverse pipe, and the air pressure produced by the air blower is matched with the air nozzle, so that the air blowing purging mechanism is used for purging hard capsules. The capsule filling machine can blow out waste materials or waste capsule shells in a cabin through high-speed flowing airflow during cleaning operation, and the problem that waste materials at the corners of equipment are difficult to clean is solved.

A system and method for controlling application rate of biological agents is disclosed. A dispersal device having a variable rate, such as a drum with a variable rotation speed, is coupled to a weight sensor and processor. The weight of biological agents in the dispersal device is thereby measured and used to calculate application rate. The dispersal device may then be operated according to one of several modes, including automated control of the dispersal device by the processor to maintain a target application rate.

This invention relates to the field of bio-infectious agent metabolites, and discloses a bio-infectious agent metabolite for the safe improvement of agricultural products and its preparation method. The bio-infectious agent metabolite is obtained by fermenting a fermentation raw material composed of a carbon source and a nitrogen source with an immobilized composite microbial agent on an organic-inorganic composite carrier. The organic-inorganic composite carrier immobilized composite microbial agent is prepared by immobilizing the composite microbial agent onto a chitosan-sodium alginate organic embedding carrier and an inorganic adsorbent carrier using immobilization loading technology. The composite microbial agent consists of *Bacillus circinus*, *Bacillus licheniformis*, *Bacillus amyloliquefaciens*, and *Bacillus subtilis*. This invention provides a method for preparing bio-infectious agent metabolites, and yields a bio-infectious agent metabolite containing carbohydrate compounds, amino acid compounds, organic acid compounds, and plant hormones, which has a quality-improving effect on agricultural products.

The utility model relates to the technical field of preparation of biological agents, and discloses a portable mixer for preparation of biological agents, which comprises a carrying device and a mixing device which form the mixer. Biological agents can be prepared through the mixing device, the mixed biological agents can be collected through the collecting assembly, the mixer can be pushed to move through the telescopic assembly, the moving effect of pushing the mixer can be improved through the moving assembly, and materials for preparing the biological agents or the biological agents can be stored through the storage assembly. Electric energy can be provided for a motor through two storage batteries, a prepared biological agent can be filtered through a filter plate, the effects that impurities of the prepared biological agent can be immediately filtered, and the mixer does not need to be carried all the time for carrying and moving are achieved, and the problems that arms are too tired and ache when the mixer is carried for a long time; and the mixed biological agent cannot be immediately filtered to treat impurities.

The application discloses an application of a nuclear receptor target gene in preparation of a biological preparation for blocking activation of diapause larvae, and relates to the field of biotechnology and parasite prevention and control. According to two nuclear receptor targets of Haemonchus contortus HCON_00101910 (regulating activity of worms) and HCON_00023750 (regulating development of larvae), the two nuclear receptor targets are combined with host progesterone and estradiol and are activated, constitute a key signal path in the spring activation process of diapause larvae, and have no homologous genes in mammals, and the safety is excellent. By constructing specific shRNA lentivirus vectors (the silencing efficiency is all greater than or equal to 60%) targeting the two genes, single target or double target synergistic intervention is realized, and the activity-development double key links of worms in the host body can be specifically blocked. The application provides a new paradigm of preventive prevention and control with high specificity and green safety, and provides core technical support for solving the seasonal epidemic problem of blood fluke disease.

A system and method for controlling application rate of biological agents is disclosed. A dispersal device having a variable rate, such as a drum with a variable rotation speed, is coupled to a weight sensor and processor. The weight of biological agents in the dispersal device is thereby measured and used to calculate application rate. The dispersal device may then be operated according to one of several modes, including automated control of the dispersal device by the processor to maintain a target application rate.

Provided herein is an automation device for identifying and collecting biological agents, which improves user convenience and enhances operational efficiency by integrating the collection and identification processes. The automation device includes: a collection unit including a movable filter tray; and an identification unit disposed apart from the collection unit and configured to wash and store collected biological agents, where a filter assembly may be mounted on the filter tray, the filter assembly being configured to collect biological agents by passing external air through a filter, and the filter coupled inside the filter assembly may be configured to automatically rotate as the filter tray moves to the identification.

In various examples, the subject matter of this disclosure relates to developing and using machine learning models to predict biological activity profiles based on multimodal datasets. An example method of predicting biological activity profiles includes: providing a multimodal dataset comprising a plurality of distinct dataset modalities (including at least one chemical structure dataset) to a foundation model, training a foundation model by applying contrastive learning to the multimodal dataset, creating a learned representation of each dataset modality, training a predictive model based on the learned representation of the chemical structure dataset modality and a classifier function that assigns modulation status for the biological target, and introducing an agent to the predictive model to predict modulation of the biological target.

The utility model discloses a filtering device for biological agent production, which relates to the technical field of biological agent production and comprises a collecting box, a filter screen frame is arranged above the collecting box, one side of the filter screen frame is rotatably connected with a rotating frame, a plurality of wavy strips positioned in the filter screen frame are fixed on one side of the rotating frame, and sliding seats are arranged in front of and behind the filter screen frame. And a sliding frame is arranged in the sliding seat. The inclined vibrating screen structure is adopted, product liquid is accelerated to pass through a filtering surface through high-frequency vibration, the filtering efficiency is greatly improved, and compared with a traditional slender cylindrical filter, the device has a wider filtering surface and can quickly treat a large amount of biological product liquid; according to the design of the device, the rapid replacement and automatic liquid discharging functions of the filter membrane are considered, automatic discharging of product liquid is achieved through the motor driving device, meanwhile, the cleaning twisting strip is communicated to clean the inner wall of the product tank, the influence of residues on the product quality is effectively avoided, and the production efficiency and the management level of product purity are greatly improved.

The utility model provides a biological agent feeding device for repairing organic contaminated soil, which belongs to the technical field of microbial strains and comprises a base, a push handle is fixedly arranged at the leftmost end of the base, a liquid storage tank and an intelligent controller are fixedly mounted on one side, close to the push handle, of the upper surface of the base, and a stirring device is arranged at the center of the top of the liquid storage tank; a through groove is formed in the upper surface, away from the push handle, of the base, a baffle is fixedly installed in the through groove and divides the through groove into a pesticide spraying groove and a soil turning groove, a pesticide storage box is arranged on the left edge of the pesticide spraying groove, and a sprinkler head is fixedly installed on the outer side face of the pesticide storage box; a rotating shaft is mounted in the soil turning groove, and soil turning plow claws are uniformly and annularly mounted on the rotating shaft; the other end of the rotating shaft penetrates through the inner wall of the through groove to be connected with the output end of a second motor, and the second motor is connected with an intelligent controller through an electric wire. The soil plowing and biological agent feeding device integrates the functions of soil plowing and biological agent feeding, time and labor cost are saved, the soil plowing and biological agent feeding device is suitable for large-area soil remediation, and working efficiency is improved.

In one example, a method of producing a concrete test coupon comprises: separating a coarse aggregate from a concrete mix to obtain a fine cementitious material; combining the fine cementitious material with water to obtain a wet concrete slurry; pouring the wet concrete slurry into a tray having one or more cavities to produce one or more concrete pieces; air drying the one or more concrete pieces in the tray; removing the one or more concrete pieces from the tray; carbonating the one or more concrete pieces to produce one or more carbonated concrete pieces; washing the one or more carbonated concrete pieces; and sterilizing the one or more carbonated concrete pieces.

The utility model discloses an anti-flatulence liquid microbial agent storage device which comprises a storage tank for storing a liquid microbial agent and a tank cover, a material opening communicated with an inner cavity of the storage tank is formed in the top of the storage tank, and the tank cover is detachably connected to the material opening; a sealing plate is arranged in the tank cover and abuts against the top face of the material opening, and a plurality of first exhaust holes communicating with the material opening are formed in the sealing plate. A limiting hole is formed in the middle of the sealing plate in a penetrating mode, a sliding rod is slidably connected into the limiting hole, a circular baffle is fixedly connected to the top end of the sliding rod, the baffle and the inner wall of the tank cover are arranged in a clearance mode, and an elastic assembly is connected to the top face of the baffle and used for driving the baffle to abut against the top face of the sealing plate. According to the storage tank, flatulence can be effectively prevented, the exhaust hole is blocked when air is not exhausted, and external impurities are prevented from entering the storage tank to pollute liquid biological agents.

The present disclosure relates to a screening system configured to identify biological agents, biological variances, pathogens, and / or genetic variances. The screening system may include an incubation zone having an incubation station for incubating multiple samples and a detector for detecting electromagnetic radiation emitted simultaneously or quasi-simultaneously from the multiple samples. The screening system may also include an optional, replaceable incubator unit housed within the incubation station. The incubation station may also include an optically based datum system used as a reference point for orienting an image of the incubation station captured by the detector and, optionally, for assisting in synchronizing the capture of spectral images corresponding to the output of a test for a pathogen or genetic variance.