Patents
Literature
3 results about "Acyl-CoA" patented technology
Efficacy Topic
Property
Owner
Technical Advancement
Application Domain
Technology Topic
Technology Field Word
Patent Country/Region
Patent Type
Patent Status
Application Year
Inventor
Acyl-CoA is a group of coenzymes that metabolize fatty acids. Acyl-CoA's are susceptible beta oxidation, forming, ultimately, acetyl-CoA. The acetyl-CoA enters the citric acid cycle, eventually forming several equivalents of ATP. In this way, fats are converted to ATP, the universal biochemical energy carrier.
Substituted benzyl-4-phenyl-thiazolyl carbamoyl compound
The invention relates to a compound of formula (I): where A is an optionally substituted heteroaryl; useful for treating disorders mediated by acyl coA-diacylglycerol acyl transferase 1 (DGAT1), e.g. metabolic disorders. The.invention also provides compositions comprising the compound for treating such disorders.
Owner:NOVARTIS AG
Method for simultaneously measuring acyl CoA and acyl carnitine
The invention relates to the technical field of biomedicine, and provides a method for simultaneously measuring acyl CoA and acyl carnitine. The method comprises the following steps: adding monopotassium phosphate, magnesium chloride and glacial acetic acid into isopropanol to form an extraction buffer solution; wherein the extraction buffer solution is used for performing a first round of extraction on a kidney sample; and mixing chloroform and methanol according to a preset volume to obtain a first solvent, pouring the first solvent into the object subjected to the first round of extraction, and carrying out two-phase extraction to obtain the extract for mass spectrometry. The invention provides a scheme for analyzing acyl CoA and acyl carnitine in a kidney sample, which does not need a special instrument and can be operated on a traditional LC-MS / MS system, so that the detection cost can be effectively reduced, and the detection efficiency is guaranteed.
Owner:XIEHE HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI & TECH UNIV
Retilitermes formosanus nucleic acid interferon and application thereof in prevention and control of
The invention discloses a reticulitermes formosanus nucleic acid interferon and application thereof in preventing and controlling termites, the three interferons are respectively designed from a Catalase gene, a Medium chain acyl CoA ligand gene and a c47753 gene in a reticulitermes formosanus body, and DNA (deoxyribonucleic acid) sequences are respectively SEQ 1A, SEQ 1B and SEQ 1C. DsRNA of CAT, ACSF2 and c47753, namely SEQ 3A, SEQ 3B and SEQ 3C, are respectively synthesized through a T7 in-vitro transcription system, and the dsRNA is the interferon of the three genes. The CAT, ACSF2 and c47753 gene interferon obtained by the invention can weaken the physiological defense capability of termites, obviously improve the control effect of metarhizium anisopliae on termites, and provide a new target gene for environment-friendly termite control.
Owner:HENAN AGRICULTURAL UNIVERSITY