The invention discloses a reticulitermes formosanus
nucleic acid interferon and application thereof in preventing and controlling termites, the three interferons are respectively designed from a
Catalase gene, a Medium chain
acyl CoA ligand
gene and a c47753
gene in a reticulitermes formosanus body, and
DNA (deoxyribonucleic acid) sequences are respectively SEQ 1A, SEQ 1B and SEQ 1C. DsRNA of CAT, ACSF2 and c47753, namely SEQ 3A, SEQ 3B and SEQ 3C, are respectively synthesized through a T7 in-vitro transcription
system, and the dsRNA is the
interferon of the three genes. The CAT, ACSF2 and c47753 gene
interferon obtained by the invention can weaken the physiological defense capability of termites, obviously improve the
control effect of
metarhizium anisopliae on termites, and provide a new
target gene for environment-friendly termite control.