1 results about "Malonyl Coenzyme A" patented technology

The application provides a genetically engineered bacterium with high yield of dihydroquercetin, a preparation method and application thereof, relates to the technical field of genetic engineering, and comprises a malonyl coenzyme A synthesis module, a tyrosine deaminase expression module, a naringenin synthesis module and a dihydroquercetin post-modification module. The enzymatic property of the fusion protein is increased by about 50% of the enzyme activity before fusion, the activity of converting naringenin into dihydroquercetin is greatly improved, and finally the yield of dihydroquercetin expressed in cyanobacteria is greatly improved. Meanwhile, BauA, MCR-C, Sam8, 4CL, CHS, CHI and expression fusion protein N33'H are expressed in cyanobacteria. The yield of dihydroquercetin is greatly increased under seawater culture conditions. The technical problem that the yield of biosynthetic dihydroquercetin is low and cannot meet the requirements of industrial application in the prior art is solved.