576 results about "Kinetic analysis" patented technology

A method of distinguishing nucleotide sequences for different nucleic acid molecules including the steps of (a) mixing a plurality of different nucleic acid molecules with polymerase molecules and nucleotide molecules, wherein the different nucleic acid molecules are attached to a surface in the form of an array of nucleic acid features; (b) determining a transient state of the polymerase molecules at the nucleic acid features; and (c) identifying a subset of nucleic acid features that correctly incorporate the nucleotide molecules based on the transient state of the polymerase molecules at the nucleic acid features, thereby distinguishing the nucleotide sequences for the different nucleic acid molecules.

A method and system for patient-specific computational modeling and simulation for coupled hemodynamic analysis of cerebral vessels is disclosed. An anatomical model of a cerebral vessel is extracted from 3D medical image data. The anatomical model of the cerebral vessel includes an inner wall and an outer wall of the cerebral vessel. Blood flow in the cerebral vessel and deformation of the cerebral vessel wall are simulated using coupled computational fluid dynamics (CFD) and computational solid mechanics (CSM) simulations based on the anatomical model of the cerebral vessel.

An apparatus and method for the kinetic analysis of tear interference is disclosed. The apparatus includes a light source for illuminating a tear film of a cornea, an optical train for modifying the light before it reaches the cornea and after it is the carrier of an image from the cornea, an image recorder to record a series of images of the illuminated tear film, and an image output for providing the series of images to a display; the series of images illustrating a tear film dispersion pattern indicative of a tear stability condition. The method includes the steps of illuminating the film on a cornea of said eye with light, recording a series of images of the illuminated film, and outputting the series of images to a display. The series of images illustrating at least one of a lipid film spread and a tear film dispersion pattern indicative of a tear stability condition.

The invention discloses a method for optimally designing dynamic property of a complete machine tool, which comprises the following steps of: establishing a complete machine tool entity parameterized model, simplifying the structure according to the analysis requirement on the dynamics and the structure characteristic of the machine tool; and guiding the simplified entity model into a finite element analyzing software ANSYS / Workbench for grid division to obtain a complete machine finite element model. The statics analysis is carried out through the ANSYS / Workbench to obtain a complete machine prestress field, and the mode of the complete machine tool under the prestress field is obtained through the mode analysis. The complete machine tool dynamics response of a main shaft, caused by a cutting force, under different rotating speeds is obtained through resonance response analysis on the complete machine tool, and the reference is provided for the searching of the dynamics thin link and the optimization design. Finally, by using the parameterized analysis method, the rule of influencing the complete machine tool dynamic property by the structure quality and the rigidity parameter is obtained, and the dynamic rigidity thin link is obtained and optimally designed.

A method of distinguishing nucleotide sequences for different nucleic acid molecules including the steps of (a) mixing a plurality of different nucleic acid molecules with polymerase molecules and nucleotide molecules, wherein the different nucleic acid molecules are attached to a surface in the form of an array of nucleic acid features; (b) determining a transient state of the polymerase molecules at the nucleic acid features; and (c) identifying a subset of nucleic acid features that correctly incorporate the nucleotide molecules based on the transient state of the polymerase molecules at the nucleic acid features, thereby distinguishing the nucleotide sequences for the different nucleic acid molecules.

The invention relates to a multi-body dynamic quick analysis modeling method for a rotary steering drilling system. The method comprises the following steps of: (1) establishing a structural unit mechanical model according to structural information of the drilling system; (2) establishing constraint models which comprises a speed constraint model, an angular velocity constraint model, a rigid body-beam clamped constraint model and a beam-beam clamped constraint model; (3) establishing an acting force model; (4) establishing a drilling system parameterized model; and (5) importing a computation model file into a multi-body dynamic simulation program to perform dynamic analysis of the drilling system so as to finish modeling. Since the mechanical model of the drilling system is established on the basis of a multi-body dynamic basic principle, rotary motion and dynamic analysis of rotary steering whole well drill string system are realized, and a well bore path is dynamically predicted. The method can be widely applied to the fields of oil-gas fields and coal bed methane exploitation.

The invention relates to a brain vascular blood circulation dynamic analysis method and the apparatus thereof. According to the cerebral circulation vascular bed anatomical model, an equivalent network model which comprises 12 pipeline units simulating the brain circulation blood dynamics is built, and the relevant parameter calculation formulas are confirmed, by utilizing the formulas, the flow rate waveform and the value inside the cartid artery, the pressure waveform, the blood pressure of the body, the diameter of the blood vessel, the flow rate waveform and the valve of the vertebral artery and the front, the middle and the rear parts on two sides inside the skull, and the characteristic and the parameter of the cartid artery and each blood vessel section inside the skull can be determined, the apparatus designed by the invention can be performed, the detecting system comprises the vessel diameter detecting of the cartid artery outside the skull, the blood pressure detecting, theblood flow rate detecting of the cartid artery outside the skull, the pressure waveform detecting of the cartid artery outside the skull, and the blood flow rate detecting on the artery inside the skull; the control system comprises a control module and a power supply module; the calculation and analysis system comprises a host computer, a peripheral equipment, and an analog-digital converter, the invention can fully analyze the brain circulation dynamic characteristic, thereby having notable effect on the early stage and the ultra early stage diagnosis and therapy of the brain vascular illness.

The invention provides a dynamics performance parameter optimizing method of a high-speed train, relates to the field of parameter design optimizing based on the dynamics simulation analysis of the high-speed train, and aims at effectively replacing a dynamics simulation model of the high-speed train by a comprehensive target neural network agent model and combining the design analysis and the multi-target optimization algorithm of the high-speed train in the multi-disciplinary field to analyze and optimize the dynamics simulation approximation model of the high-speed train. The method specifically comprises the steps of building a multi-rigidity dynamics simulation model for the high-speed train; determining related important input / output design spaces; selecting sampling strategy to obtain a design space sample set suitable for the dynamics performance analysis of the high-speed train; improving the generalization accuracy of the comprehensive target neural network by the bayesian regularization method; adjusting the number of nodes in a hidden layer to build the comprehensive target neural network agent network model of which the error is controlled to be within a certain of range; performing multi-target optimization through the intelligent differential evolution algorithm by using the improved comprehensive target neural network agent network model to obtain the optimized high-speed train design parameters. The method is mainly applied to the dynamics analysis and design optimization of the high-speed train.

The invention provides a coaxial rigid rotor coupling pneumatic elastic response analysis method, and belongs to a helicopter kinetic analysis technology. The method is characterized in that according to the operation and control characteristics of a coaxial rigid rotor helicopter, a balance equation optimization solution method is built, and an optimization solution is found according to the given target and constraint conditions. According to the characteristic of complicated coaxial rigid rotor flow field environment, a rotor flow field is calculated by using a computational fluid dynamic method based on an Euler / N-S equation; and then, the coupling pneumatic elastic response is calculated by using a computational fluid dynamic / computational structural dynamic loose coupling analysis method. The coaxial rigid rotor coupling pneumatic elastic analysis method has the advantage that when the analysis method is used, balance operation and control parameters, blade response, rotor loads and the like of the coaxial rigid rotor helicopter can be calculated. The method has good analysis precision and engineering applicability; the relying of the development process on the test can be reduced; and the design period and the development cost can be greatly reduced.

A football having a prolate spheroidal shape including longitudinally spaced apart first and second ends. The football is capable of being analyzed under computational fluid dynamics analysis, and includes upper and lower central regions. Each positioned between first and second upper and lower end regions, respectively. The football further includes a bladder, a cover, a plurality of boundary layer trip mechanisms coupled to the upper and / or lower central regions, and a lacing coupled to the upper central region. The analysis includes first and second configurations. The first configuration is conducted on the football with the trip mechanisms, and the second configuration is conducted on the football without the trip mechanisms. The first and second configurations provide first and second drag coefficients, respectively. The first coefficient is at least 3 percent lower than the second coefficient. The length of the upper and lower central regions is defined by the lacing.

The invention provides a method for reliability modeling and evaluation of a dynamic cascade coupling electromechanical system. The method is based on a physical background of a complex electromechanical system and is capable of carrying out research on reliability of the electromechanical system based on a dynamics response model, and an established reliability network model of the electromechanical system is capable of more accurately describing the characteristics of dynamic, cascading and coupling of the complex electromechanical system, so that reliability of the electromechanical system, which is obtained based on the network model, is more accurate and credible; meanwhile, by utilizing a method of combining dynamics analysis and uncertainty analysis, transfer of uncertain information from a bottom layer to a top layer of the network model is described, and the difficulties that an aerospace mechanism system has a response uncertainty character and system reliability information cannot be obtained through experiment measures due to large experimental expenses, long period, large technical difficulty and expensive product cost are solved.

An RNN-based gene regulatory network construction and dynamic differential analysis method comprises the first step of gene dynamic regulation network construction based on a deepRNN, the second step of time-sequence variation and evolution analysis based on an intra-subtype dynamic regulation network, and the third step of network differential evolution analysis based on an inter-subtype dynamic regulation network, wherein the evolution analysis of different subtype networks comprises kinetic analysis, differential analysis and perturbation analysis. The RNN-based gene regulatory network construction and dynamic differentiation analysis method is high in precision.

The invention relates to a modal synthesis dynamic modeling and analysis method for an automobile driving axle system. The method is characterized by comprising the steps that 1, a finite element model of all components of a driving axle is established, boundary nodes are defined according to the connecting relation between the components, a modal synthesis model of all the components is established, and a modal synthesis rigidity matrix and a mass matrix of all the components are obtained; 2, a connecting relation model of all the components is established; 3, the modal synthesis rigidity matrix and the mass matrix of all the components are assembled according to the connecting relation, a complete modal synthesis dynamic model of the driving axle system is established, and a rigidity matrix and a mass matrix of the driving axle system are obtained; 4, natural vibration frequency and a regular vibration mode of the dynamic model of the driving axle system are calculated, and a mode superposition method is adopted to calculate the dynamic response of the driving axle system under excitation of dynamic engaging force of gears of a main reducing gear. In the whole modeling process, high universality and calculating efficiency are achieved, and the method can be widely applied to dynamic analysis of a gear transmission system.

The invention comprises systems, methods and arrays for identification and optimization of novel peptide binders to protein targets. Embodiments include steps of peptide binder discovery, core peptide maturation, N-terminal and C-terminal extension and kinetics analysis of the final peptide binder.

The invention discloses an analysis method of motor crank dynamics, which includes that: in Hypermesh software, a crank system is divided by finite element mesh generation into a crank, a flywheel, a belt pulley, a timing gear and a main bearing seat etc.; use Nastran software to execute the reduction solving of a finite element substructure; in EXCITE software, construct a model of the crank system dynamics, and exert the corresponding boundary condition on elements to implement simulation calculation; use the Nastran software to implement restoration solving of dynamic stress on the crank, perform post-processing and execute fatigue analysis on dangerous points; reasonably evaluate the crank system according to the results, and if the structure is not reasonable, the structure optimization is still needed. The method uses EXCITE calculation technique to execute dynamics analysis on the motor crank, obtains the strength and the fatigue parameters of the motor crank, and further evaluates the structure parameters of the crank and the related parts of the motor reasonably, therefore, making the improvement thereof.

The invention provides a polyhedron collision dynamics analysis method for the process of a space manipulator grabbing a non-cooperative target. The method comprises the following steps of (1) establishing a dynamical model of a space manipulator; (2) expressing the tail end of the space manipulator as a combination of multiple polyhedrons, and expressing the non-cooperative target as a polyhedron; conducting collision detection on the polyhedron expressing the non-cooperative target through the multiple polyhedrons expressing the tail end of the space manipulator, and detecting whether two different polyhedrons collide or not; if not, repeating the step (2), and if yes, detecting the collision intersection point of the two different polyhedrons; (3) solving collision force in the process of the space manipulator grabbing the non-cooperative target through a non-linear damping model according to the collision intersection point of the two different polyhedrons; and (4) substituting the collision force into a dynamical equation to obtain the collision response in the grabbing process. The polyhedron collision dynamics analysis method is reasonable in design, simple in implementation, high in analytical calculation fidelity and closer to the practical situation.

The invention provides a fast and reliable artificial bone prosthesis manufacturing method which includes: using the CT or MRI scanning technology to obtain the image data of all bones of a human body under a healthy state, and a building a database of the image data; generating three-dimensional models of the bones by the bone image data in the database; performing optimization design and analysis, which includes constructions of bone cavities, bone scaffolds and bone micropore basal bodies and virtual simulation analysis such as statics analysis, kinematics analysis and kinetics analysis, on the three-dimensional models of the bones; using additive manufacturing to manufacture artificial bone prosthesis on the basis of the optimized three-dimensional models of the bones; performing bioactivity treatment on the manufactured artificial bone prosthesis; performing quality inspection on the artificial bone prosthesis after the bioactivity treatment. By the method, the artificial bone prosthesis high in reliability can be manufactured fast aiming at each patient, disability possibility of the patient is lowered, and material waste is avoided.

The invention discloses a high-speed elevator operating parameter monitoring method based on kinetic analysis, and belongs to the field of elevator lift car safety control systems. The high-speed elevator operating parameter monitoring method based on kinetic analysis is realized by the following technical scheme that (1) a vibration acceleration sensor is installed in an elevator lift car, vibration signals are collected and remotely transmitted to a CPU, and a vibration displacement diagram is obtained through integral preliminary calculation; (2) a tension detection device is installed on load bearing beam of an elevator, and a tension unbalance coefficient B of an elevator traction steel wire rope is calculated according to a formula (1); (3) an elevator balance coefficient Kping is calculated; (4) the braking distance of a brake is measured; and (5) a noise sensor is arranged in an elevator lift car and used for collecting noise signals. By detecting a series of parameters relatedto vibration and noise of the elevator lift car and monitoring and evaluating real-time operating characteristics of the elevator lift car, a decision and a guarantee are provided for safe operationof the high-speed elevator.

The invention discloses a method for automatically converting data between dynamics analysis software and finite element analysis software, comprising the following steps of: starting the finite element analysis software to perform model flexiblization and outputting a modal neutral file (MNF); starting the dynamics analysis software, loading a virtual prototype model, reading the MNF, performing kinematics and dynamics analysis and outputting a load file; applying a load in the load file to a flexible body, performing stress and strain analysis on the flexible body and outputting stress and strain data; and circularly performing the steps and outputting an optimal operating condition and the stress and strain data. The method for automatically converting data can really integrate the powerful finite element function of the finite element analysis software and the powerful dynamics analysis function of the dynamics analysis software for combined application and provide an automatic, simple, convenient, high-efficiency and reliable realization means for achieving the mechanical property analysis and the operating condition analysis of a mechanical system.

The invention discloses a bidirectional fluid-solid coupling three-dimensional numerical simulation method for a high-speed pantograph. The method comprises the following steps: firstly, constructinggeometric models of a fluid domain and a solid domain of the high-speed pantograph; secondly, according to the model constructed in the first step, conducting grid division on a pantograph fluid domain and a pantograph solid domain respectively; then setting material parameters, initial conditions and boundary conditions of a fluid domain and a solid domain; adding a pantograph fluid-solid coupling data exchange surface, and performing bidirectional fluid-solid coupling numerical analysis of the high-speed pantograph; and finally, obtaining a pantograph displacement cloud picture and a stresscloud picture according to a kinetic analysis result in the step 4, and obtaining an aerodynamic time-history curve of each part of the pantograph according to a hydrodynamic analysis result. On the basis of the bidirectional fluid-solid coupling theoretical model, the change of the operation posture of the pantograph under the aerodynamic force effect is considered, aerodynamic characteristic calculation and stress deformation research of the pantograph under the high-speed airflow effect are achieved through numerical simulation, and the nature of the aerodynamic characteristics of the pantograph can be reflected more objectively.

The invention relates to a position attitude control method of a four-rotor unmanned aerial vehicle with unbalance loads, and belongs to the technical field of control of unmanned aerial vehicles, which aims at solving the problem of the unmanned aerial vehicle failing to continue to stably run due to unknown center of gravity and uncertainty in installation position in the process of loading unbalanced load. The position attitude control method comprises the following steps of firstly, deriving a kinematics model and a dynamics model before and after the unbalance load is loaded on the four-rotor unmanned aerial vehicle by coordinate conversion and dynamics analysis; obtaining the measuring data of a sensor in the flight process, utilizing a Kalman filtering method to obtain the high-precision and non-lagging flight state, and distinguishing the approximate location of center of gravity by the flight states; designing a position attitude controller and a position controller of the four-rotor unmanned aerial vehicle, and improving the controller by compensating the rotation speed of a propeller, so as to offset the additional rotary movement and linear movement due to location change of center of gravity. The position attitude control method is suitable for estimating the location of the center of gravity in the takeoff and hovering process of the four-rotor unmanned aerial vehicle, and establishing a compensation controller.

The invention discloses a high-speed angular contact ball bearing damage fault dynamic analysis method which is characterized by including the steps of (1) building a high-speed angular contact ball bearing dynamic model, (2) building a high-speed angular contact ball bearing damage fault model, (3) integrating the damage fault model with the high-speed angular contact ball bearing dynamic model to build a high-speed angular contact ball bearing damage fault dynamic model, and (4) carrying out numerical solution to obtain a dynamic response of a bearing under a fault situation and achieving dynamic analysis of a high-speed angular contact ball bearing damage fault. According to the method, three-dimensional motions, relative sliding and lubricating traction effects of the bearing element are taken into consideration, a comprehensive model of the damage fault is built in terms of mutual approach quantity, Hertz contact stiffness and contact load functions, analysis accuracy is improved, and the method for high-speed angular contact ball bearing damage fault dynamic researches is accurate.

The invention discloses a cyanobacterial bloom predicting method based on a non-linear kinetic time-series model, which belongs to the water environment predicting field. The method comprises the following steps: using the blue algae growth rate as a time-varying parameter; creating a non-linear kinetic time-series model for the cyanobacteria growth with double nutrient salt cycling; using the combination of the numerical algorithm and the intelligent evolutionary algorithm, optimizing the constant parameters in the non-linear kinetic time-series model for the cyanobacteria growth; through setting the multivariate time-series model to realize the prediction of the time-varying parameter and the cyanobacteria biomass and through using the bifurcation theory and the central manifold theory to make a nonlinear kinetic analysis of the cyanobacteria growth time-varying system, obtaining the outbreak conditions for a cyanobacteria bloom so as to make an early warning of the bloom outbreak. The method proposed by the invention not only determines the conditions for a cyanobacteria bloom outbreak, but also improves the bloom prediction accuracy, providing an effective reference for an environmental protection department and governance decisions for water environment treatment.

The invention relates to a spot-welding connection failure value simulation system in the car bodywork manufacturing engineering field. In the invention, a circle-stress failure criterion generating module obtains nugget circle stress distribution form according to the failure mode of the spot-welding connection in a strike process to generate the circle stress failure criterion; a failure extreme value stress and an index-parameter obtaining module obtain welding-spot critical failure stress extreme values and dimensionless stress sub-item index initial values under the condition of the peak values of four exterior loads; four types of sample value models which are pulling-cutting, pulling-extending, pulling-bending and pulling-twisting are established in a welding-spot connection value simulation module; an explicit dynamics analysis module couples circle stress failure criteria and obtains the continuous distributed inner stress of a welding-spot unit model and an extreme value stress borne by the welding-spot unit during failure time by simulation; a welding-spot failure material databank module stores the critical failure stress extreme values and the dimensionless stress sub-item index initial values of each stress component. The system not only can enhance the impact simulation precision without impact on the calculation efficiency, but also can reduce the design and exploitation cost.

The invention discloses a method for converting data between ADAMS software and Pro / E software, which comprises the following steps: firstly, performing kinematics and kinetics analysis by using an ADAMS, and when dimension parameters of a part model need to be changed according to the analysis result or design requirement, using ADAMS macro command and operating system batch processing command statements to directly start three-dimensional parameter modeling software Pro / E from the ADAMS; secondly, finishing automatic modification, reconstruction and virtual assembly of a three-dimensional complete machine or the part model in the Pro / E, applying constraint by using an interface module MECH / Pro, and finally adopting a command statement of Pro / TOOLKIT to automatically return to the ADAMS from the Pro / E; thirdly, performing the kinematics and kinetics analysis again, outputting a result if the requirement is satisfied, otherwise, repeating the steps until the requirement is satisfied; and fourthly, in the ADAMS software, outputting and storing dimension data of a module to be modified in the form of an independent data file. The method provides an automatic, simple and convenient, highly-efficient and reliable solution for mechanical design and analysis, and improves the design precision and the design efficiency of products.

The invention provides a global-local hybrid unmanned ship path planning method based on dynamic constraints. The global-local hybrid unmanned ship path planning method comprises the steps of: S1, constructing an unmanned ship kinematics model, and conducting kinetic analysis; S2, considering a safety range of an unmanned ship, realizing the planning of a global path of the unmanned ship by adopting a storage node mode, and constraining the safe driving of the unmanned ship by optimizing the generated path points; S3, for a dynamic unpredictable environment, constructing a hierarchical structure based on an FDM fuzzy decision module and an FDW precise dynamic window module, and realizing the planning of a local path of the unmanned ship, precisely taking drivable forward, heading angular velocities and acceleration into account in the planning of the local path, and generating a traceable path that enables real-time local collision avoidance; S4, and fusing a global path planning scheme and a local path planning scheme of the unmanned ship to form a global-local hybrid obstacle avoidance strategy. According to the global-local hybrid unmanned ship path planning method, virtual pathpoints are inserted into the global optimal path, so that global and local path planning is perfectly combined, and the whole path tracking task is completed.

The invention relates to a method for calculating rotor dynamics performance of a multi-parallel-axis system. The method comprises the steps specifically as follows: step (1), selecting an analysis object and a calculation type, inputting parameters of a bearing-rotor system, finishing pre-processing operations like discretization of the rotor system; step (2), calling a bearing calculation program, calculating dynamic and static characteristic parameters of each bearing, forming a rotor dynamics equation of a parallel axis system which gives consideration to gear engagement according to the selected analysis object and calculation type; and step (3), calling a solving function to calculate a feature value and a feature vector of a dynamics differential equation, converting the feature value and the feature vector into dynamics characteristic result data through dimension so as to finish calculation and analysis of system stability, critical rotation speed, forced vibration response and vibration mode. According to the method disclosed by the invention, calculation and analysis means for dynamics performance of the multi-parallel-axis system, which can be applied to actual engineering, are developed on the basis of solid theoretical research; the calculated rotor system comprises supports of various types; therefore, combination of bearing calculation and rotor system dynamics analysis is implemented better.

The invention discloses a method for automatically converting data among kinetic analysis, three-dimensional modeling and finite-element analysis software, which comprises the steps of: starting mechanical system kinetic analysis software, and loading a virtual prototype to carry out kinematics and dynamics simulation; generating a CMD command file recognized by the mechanical system kinetic analysis software in the three-dimensional modeling software by using relevant plug-ins; deriving a mode neutral file corresponding to a model in the finite-element analysis software; reading the generated CDM command file and the mode neutral file by using the mechanical system kinetic analysis software and carrying out rigid-flexible mixed simulation; circularly correcting and flexing the model, and displaying a better result on screen and storing data files. The method for automatically converting the data is applied to complex mechanical system design and analysis, which can improve the design accuracy and the design efficiency of products.

A method for tire parameter derivation, tire cornering characteristic calculation and tire design is used with a tire dynamic model constituted by using a plurality of tire dynamic element parameters including stiffness and friction coefficient and parameter defining a distribution of contact pressure of the tire. The parameters and tire cornering characteristic are derived by using the combined sum of squared residuals being obtained by weighted addition of a first sum of squared residuals of lateral force and a second sum of squared residuals of self-aligning torque. The tire dynamic model is a model for calculating a lateral force and for calculating a self-aligning torque separately as a lateral force-based torque component generated by the lateral force applied on a contact patch of the tire and a longitudinal force-based torque component generated by a longitudinal force applied on the contact patch of the tire.