9results about How to "Non-toxic" patented technology

This invention discloses a method for preparing a thermally conductive and insulating coating, comprising the following steps: taking a base resin, adding an active diluent, reducing the viscosity of the base resin and mixing it evenly under heating and stirring conditions, and then stopping the heating; sequentially adding modified hexagonal boron nitride nanosheets and nano-Al 2 O 3 The thermally conductive and insulating coating is prepared by dispersing coupling agent, leveling agent, initiator, stabilizer, curing agent, and defoamer for several hours. The modified hexagonal boron nitride nanosheets are hexagonal boron nitride nanosheets modified with amino acids. The thermally conductive and insulating coating prepared by the method provided by this invention has good thermal conductivity and good insulation properties on circuit boards, exceeding 25kV / mm. The entire production process is pollution-free, non-toxic, and more environmentally friendly, and the entire process is relatively simple.

The application provides a heterocyclic quaternary acid and a preparation method and application thereof. The heterocyclic quaternary acid has a structure shown in formula I, wherein Y is selected from a substituted or unsubstituted heterocyclic group, R1 and R2 are independently selected from a linear or branched alkyl group with 1-6 carbon atoms or a substituted or unsubstituted aromatic ring. 10 The heterocyclic quaternary acid has the advantages of good biological compatibility and low toxicity due to the presence of an amide bond, and is suitable for synthesizing a low-toxicity plasticizer.

This invention belongs to the field of probiotic screening and application technology, specifically relating to a strain of *Lactobacillus paracasei* and its application in the prevention and treatment of colonic polyps and colon cancer. The *Lactobacillus paracasei*, named *Lactobacillus paracasei* V85, was deposited on January 15, 2026, at the China Center for Type Culture Collection (CCTCC), Wuhan University, China, with accession number CCTCC NO: M2026124. The *Lactobacillus paracasei* V85 provided by this invention is sensitive to common antibiotics and has good biosafety; it possesses strong antioxidant function and a strong inhibitory effect on hemolytic streptococci; it can produce a strong agglutination effect with hemolytic streptococci, which is beneficial for inhibiting the colonization of hemolytic streptococci in the intestine, reducing the risk of colonic polyps and colon cancer caused by hemolytic streptococci, and can promote the proliferation of *Akkermansia myxophilus*. It can be used to prevent and treat colonic polyps and colon cancer caused by hemolytic streptococci, and has broad application prospects.

The invention provides a preparation method and application of a citric acid modified Cd-MOF material, and belongs to the technical field of metal organic framework materials. The citric acid modified beta-cyclodextrin metal organic framework (CA-beta-CD-MOF) is synthesized by adopting a chemical grafting and steam diffusion method, and the adsorption performance and the reusability of the citric acid modified beta-cyclodextrin metal organic framework (CA-beta-CD-MOF) are systematically researched. Parameters such as concentration, dosage, pH and the like of citric acid are associated, the adsorption effect of the citric acid on heavy elements in a portable solution is investigated, and the adsorption capacities of the citric acid on anionic dye Congo red (CR) and heavy metal ions (Cu < 2 + >) are as high as 900.9 and 287.4 mg.g <-1 > respectively. The citric acid modified beta-cyclodextrin metal organic framework (CA-beta-CD-MOF) obtained by the invention has the characteristics of being simple, green, environment-friendly and reusable, has excellent adsorption performance, and can be used for simultaneously removing organic dye and heavy metal ion pollution in water.

The application discloses a kind of preparation auricularia auricular polysaccharide / casein emulsion gel and its preparation method and application.The preparation method of the application includes the following steps: 1) auricularia auricular polysaccharide aqueous solution is mixed with casein aqueous solution, to obtain protein-polysaccharide complex solution;2) water phase is mixed into oil phase, the water phase is the protein-polysaccharide complex solution, and the obtained mixture is ultrasonically homogenized, to obtain emulsion;3) gluconic acid-delta-lactone is added to the emulsion and mixed, incubated, to obtain auricularia auricular polysaccharide / casein emulsion gel.The auricularia auricular polysaccharide / casein emulsion gel disclosed in the application is applied to curcumin encapsulation.After adding auricularia auricular polysaccharide, the gel performance of casein emulsion gel is significantly improved;After adding auricularia auricular polysaccharide, the loading rate of curcumin loaded in casein emulsion gel is significantly increased.

This invention discloses an antimicrobial 10-peptide, characterized by the sequence: w-k-r-w-r-r-w-w-r-r(dTrp-dLys-dArg-dTrp-dArg-dArg-dTrp-dTrp-dArg-dArg), where all amino acids are D-type amino acids. The antimicrobial peptide provided by this invention exhibits good antimicrobial activity against a variety of pathogenic bacteria. This antimicrobial peptide can be synthesized using the Fmoc solid-phase chemical method, which is easy to synthesize and exhibits good in vivo antimicrobial activity. This antimicrobial peptide exhibits broad-spectrum killing activity against multidrug-resistant Acinetobacter baumannii, carbapenem-resistant Pseudomonas aeruginosa, as well as standard strains of Acinetobacter baumannii, Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli, Enterobacter cloacae, methicillin-resistant Staphylococcus aureus, and Staphylococcus aureus. It has low hemolytic toxicity, and at low to medium concentrations (2 μg / mL to 32 μg / mL), the cell survival rate can reach more than 50%. It has no toxic effect on cells, good stability, strong operability, and low cost.

The application discloses a kind of fluorine-containing amphiphilic block polymers, its preparation method and application, a kind of fluorine-containing amphiphilic block polymer structure is: Wherein, R1It is hydrophilic group, R2It is fluorine-containing hydrophobic group, n, m are polymerization degree.The fluorine-containing amphiphilic block polymer of the application is synthesized by controllable polymerization method from hydrophilic material polyethylene glycol and hydrophobic material fluorine-containing acrylate, can freely change the proportion of hydrophilic material and hydrophobic material, maximum limit load hydrophobic material perfluoro crown ether;The fluorine-containing amphiphilic block polymer of the application synthesis process is simple, can be self-assembled into spherical particles in aqueous solution, can stably exist in blood, reach tumor area by infrared light illumination to produce reactive oxygen, under the condition of not being illuminated, cell has no toxic effect.

This invention belongs to the field of photo-evaporation desalination of water, specifically relating to a composite photoevaporator for photo-evaporation desalination and its preparation method. Carbon nanotubes, which possess excellent light absorption and water transport capabilities, are dispersed in biomass materials. Simultaneously, a layer of copper acetate is sprayed onto the surface of the biomass materials containing carbon nanotubes, forming copper particles after carbonization. The photoevaporator prepared by this invention combines metal, carbon nanotubes, and biomass materials, exhibiting contrasting hydrophilic and hydrophobic properties and strong salt resistance.

The utility model discloses a thin film for food, which relates to the field of thin films, and has the technical scheme that the thin film comprises a plurality of sections, adjacent sections are divided by tooth lines, any section is provided with a round sheet, the round sheet and the sections are divided by the tooth lines, a plurality of extension sections are integrally formed at the edge of the round sheet, and the extension sections and the sections are divided by the tooth lines. The contact area of the film and a food container is increased through the extension sections, so that the connection strength of the film and the container is improved, the sealing effect of the film is guaranteed, the polypropylene film has the advantages of being light in weight, non-toxic, odorless, moisture-proof and the like, the drawing force borne by the wafer is more uniform through the two extension sections, wrinkles are further reduced, and the service life of the film is prolonged. Meanwhile, the material utilization rate is ensured.