114 results about "Hydroxyapatite composite" patented technology

The invention relates to the field of anticorrosive paint, in particular to anticorrosive paint containing lanthanum cerium oxide and a preparation method of the anticorrosive paint. The invention relates to an anticorrosive coating containing lanthanum cerium oxide. The anticorrosive coating is prepared from the following raw materials: 28 to 45 parts of ultraviolet stable composite film forming matter, 5 to 10 parts of composite rare earth filler, 6 to 12 parts of supported synergistic antirust agent, 18 to 30 parts of mixed solvent, 0.8 to 2.5 parts of dispersing agent, 2.7 to 5.3 parts of functional additive and 0.5 to 1.2 parts of nano montmorillonite, the composite rare earth filler is lanthanum cerium oxide-hydroxyapatite composite powder with a core-shell structure, wherein lanthanum cerium oxide is used as a core, hydroxyapatite is used as a shell, and the thickness of the shell layer is 10-20 nm; the ultraviolet stable composite film forming substance comprises epoxy resin and ultraviolet grafting modified polyurethane in a weight ratio of 1: (0.6-2.2); the supported synergistic antirust agent is a mixture of mesoporous silica supported benzotriazole and zinc molybdate. And the obtained coating is high in adhesive force and long in service life.

The invention discloses a titanium-based hydroxyapatite composite coating and a preparation method thereof. The problems that a traditional coating is weak in interface bonding, single in porosity and mismatched in drug sustained release are solved. The composite coating comprises a gradient component layer and a bionic porous outer layer which are sequentially stacked on the surface of a titanium substrate, wherein the gradient component layer comprises a bottom layer (a titanium-based hydroxyapatite transition layer, 70-80% of HA and bonded through Ti-O bonds) and a middle layer (an HA / bioglass composite layer, 50-70% of HA and 10-20% of bioglass); the bionic porous outer layer is a porous HA layer, the porosity is 40-60%, the porosity is gradually increased in a gradient mode in the direction away from the titanium substrate, surface layer pores are loaded with anti-infection drugs, and inner layer pores are loaded with bone growth factors. The method realizes improvement of the interface bonding strength of the coating, consideration of mechanical and biological activity and staged slow release of the medicine, and is suitable for the field of bone joint implantation.

The invention discloses a natural plant-based spinning yarn and a preparation method thereof, and relates to the technical field of spinning yarns. When the natural plant-based spinning yarn is prepared, palm fibers are pretreated with a sodium chlorite solution and a sodium hydroxide solution, and pretreated palm fibers are prepared; reacting the pretreated palm fibers with ammonium dihydrogen phosphate to prepare phosphorylated modified palm fibers; reacting the phosphorylated modified palm fibers with calcium nitrate, diammonium hydrogen phosphate and allylphosphonic acid to grow hydroxyapatite in situ, so as to prepare hydroxyapatite composite palm fibers; 4-allyl thiosemicarbazide reacts with salicylaldehyde to prepare an antibacterial agent intermediate, and the antibacterial agent intermediate is complexed with copper ions to prepare an antibacterial agent; grafting an antibacterial agent and an anti-aging agent on the hydroxyapatite composite palm fibers to prepare modified palm fibers; and spinning the modified palm fiber to obtain the natural plant-based spun yarn. The prepared natural plant-based spinning yarn has the advantages of being high in breaking strength, antibacterial, flame-retardant and anti-aging.

The invention relates to a flame-retardant polyester fiber based on modified hydroxyapatite and a preparation method of the flame-retardant polyester fiber, and belongs to the technical field of functional fibers. The preparation method comprises the following steps: S1, adding hydroxyapatite into a monophenyl phosphate solution, and carrying out ultrasonic treatment and heating reaction to obtain modified hydroxyapatite; s2, granulating the modified hydroxyapatite and the polyester powder to obtain a flame-retardant polyester master batch; s3, spinning the flame-retardant polyester master batch and the polyester chips to obtain the flame-retardant polyester fiber based on the modified hydroxyapatite. Phosphate groups and calcium ions in the flame-retardant polyester fiber can form a protective carbon layer in the pyrolysis process, and combustion of the polyester fiber is inhibited; and aromatic groups can promote char formation, so that the flame-retardant effect and the anti-dripping effect are further improved. Through the synergistic effect of the three components, the modified hydroxyapatite composite material shows relatively high efficiency and stability in flame retardance.

The present invention belongs to the technical field of material preparation, and specifically relates to the preparation and application of a hydroxyapatite microsphere composite injection. The present invention first provides a method for preparing hydroxyapatite composite microspheres, wherein the hydroxyapatite composite microspheres are modified hydroxyapatite microspheres with amino groups and carboxylic acid groups, and the method comprises preparing hydroxyapatite microspheres, preparing modified hydroxyapatite microspheres with amino groups, and preparing modified hydroxyapatite microspheres with amino groups and carboxylic acid groups. Without introducing a toxic crosslinking agent, the electrostatic adsorption between the groups is utilized to achieve uniform dispersion of the hydroxyapatite microspheres in an aqueous solution.

The invention relates to the technical field of biological tissue adhesives, in particular to a biological tissue adhesive composition. The biological tissue adhesive composition comprises a powder A, a powder B and a powder C, wherein the powder A is obtained by curing calcium silicate and acidic calcium phosphate in a curing liquid, curing, drying and crushing; powder B: bivalent metal salt; powder C: phosphorylated amino acid; and an aqueous solvent; the biological tissue adhesive is used for bone adhesion and bone repair. According to the biological tissue adhesive composition provided by the invention, a silicate / hydroxyapatite composite material with a bone induction function is synthesized through optimized bone cement reaction, a curing liquid is added to react with phosphorylated amino acid, and a bone adhesive material is obtained through organic and inorganic material coordination reaction; the bone repairing and regenerating capability and the bone bonding capability are good.

The invention relates to a silicon-doped hydroxyapatite (at) MnO2 composite material and a preparation method and application thereof.The preparation method comprises the following steps that a permanganate solution is added into a silicon-doped hydroxyapatite suspension for a reaction, and the mass ratio of silicon-doped hydroxyapatite to permanganate is (5-8.75): (0.01-0.024); and after the reaction is finished, carrying out post-treatment to obtain the silicon-doped hydroxyapatite (at) MnO2 composite material. According to the preparation method, the permanganate solution is doped into the silicon-doped hydroxyapatite suspension for reaction, the permanganate solution can be decomposed and grow on the silicon-doped hydroxyapatite, a core-shell structure with the silicon-doped hydroxyapatite as a core and MnO2 as a shell is formed, and the obtained silicon-doped hydroxyapatite and MnO2 composite material is uniform in morphology, high in specific surface area and high in specific surface area. And a uniform shell layer is formed by controlling the dosage ratio of the permanganate to the silicon-doped hydroxyapatite, so that low cytotoxicity or even no cytotoxicity is ensured, and remarkable thermal response performance is achieved.

The invention discloses a preparation method of a composite alveolar bone repair stent. The method comprises the following steps: mixing nano-scale hydroxyapatite powder and medical-grade PLA plastic powder according to a mass ratio of 10-20%: 1, melting and drawing wires to obtain a PLA / HAP wire for 3D printing, setting 3D printing parameters, introducing a bone repair scaffold three-dimensional model, starting printing to obtain a PLA / HAP composite material bone repair scaffold, soaking the scaffold in a 1-3mg / mL BMP bone morphological protein solution, and carrying out 3D printing to obtain the bone repair scaffold with the PLA / HAP composite material bone morphological protein / PLA / HAP composite material bone morphological protein / PLA / HAP composite material bone morphological protein / PLA / HAP composite material bone morphological protein composite material. The BMP-PLA / HAP composite material bone repair scaffold is obtained. The hydroxyapatite / PLA composite material prepared by adopting a 3D printing technology, taking the nano-scale hydroxyapatite powder and the medical-grade PLA plastic powder as raw materials and loading the BMP bone growth factor with high biological inductivity has high strength, high hardness and impact resistance, and can be used for preparing the medical-grade hydroxyapatite / PLA composite material. The invention aims to provide a safer and more effective bone graft material for clinically repairing alveolar bone defects.

The invention provides a preparation method of a hydroxyapatite nanowire, a polyether-ether-ketone / hydroxyapatite composite material and a preparation method of the polyether-ether-ketone / hydroxyapatite composite material, and belongs to the field of bone repair. The invention provides a preparation method of a hydroxyapatite nanowire, which comprises the following steps: mixing monohydroxy alcohol, an aliphatic template agent, an alkaline compound, calcium salt, phosphate and water to obtain a suspension; the suspension liquid is subjected to a hydrothermal reaction, and the hydroxyapatite nanowire is obtained; the temperature of the hydrothermal reaction is 160-240 DEG C, and the time is 12-48 hours. According to the preparation method disclosed by the invention, by selecting a proper template (aliphatic template agent) and optimizing the temperature and time of a hydrothermal reaction, the hydroxyapatite nanowire which has a specific shape and a high length-diameter ratio, keeps the inherent biological activity and also shows excellent mechanical properties is prepared. The hydroxyapatite nanowire is used as a filler to be doped into the polyether-ether-ketone, so that the biological activity of the material can be improved on the basis of not reducing the mechanical property of a matrix.

The invention provides a method for preparing a modified hydroxyapatite gel drug sustained-release material, and belongs to the field of hydroxyapatite application. The preparation method comprises the following steps: firstly, carrying out ball milling on a high-molecular polymer and hydroxyapatite to carry out structure modification on the hydroxyapatite, so as to improve the load rate of the hydroxyapatite on a medicine and improve the wettability of the hydroxyapatite in a PVP (Polyvinyl Pyrrolidone) aqueous solution, thereby preparing a high-stability modified hydroxyapatite dispersion liquid; and then adding PVA (Polyvinyl Alcohol) to obtain the modified hydroxyapatite composite gel drug sustained-release material. PVP and PVA are cross-linked to form a gel system, coating of hydroxyapatite is achieved, the stability of hydroxyapatite in an acid environment is improved, and stable release of drugs is achieved. The technology is simple, efficient, low in comprehensive cost and suitable for industrial production.

The invention provides a composite sun-screening agent based on an encapsulation technology as well as a preparation method and application of the composite sun-screening agent. The preparation method of the composite sun-screening agent comprises the following steps: fully dispersing hydroxyapatite nanoparticles in an alkaline solvent, adding a dopamine monomer, and carrying out oxidative polymerization reaction, centrifugal washing and drying to obtain HAP-PDA composite nanoparticles; and fully dispersing the HAP-PDA composite nanoparticles in a solvent, adding a mixed solution of a chemical sun-screening agent and an antioxidant and a surfactant, and performing encapsulation reaction and centrifugation to obtain the product. According to the invention, a polydopamine and hydroxyapatite composite encapsulation technology is innovatively adopted, so that the stability and biocompatibility of the sun-screening agent and the antioxidant are remarkably improved, the sun-screening effect is enhanced, and the product is endowed with a lasting sun-screening effect and excellent oxidation resistance. According to the invention, the limitation of a traditional sunscreen product is broken through, and safer, more efficient and more comfortable sunscreen experience can be provided for consumers.

Provided herein are chromatography media comprising a porous solid substrate (such as a membrane, a metal, or a metal alloy) coated with hydroxyapatite (HA). Also provided are chromatography media comprising the HA coated substrate, and uses thereof. Thus, the present disclosure provides chromatographic media comprising a porous solid substrate coated with HA, such as a membrane, metal, or metal alloy. Also provided are chromatography media comprising the HA coated substrate, and uses thereof. A method of preparing the HA coated substrate is also provided.

The invention relates to the technical field of orthopedic repair materials, in particular to a polycaprolactone and nano-hydroxyapatite composite bone repair implant and a preparation method thereof.The preparation method comprises the steps that PCL-PLA serves as a shell material, citric acid serves as a core material, and n-HA degradation accelerator microcapsules are prepared; the preparation method comprises the following steps: weighing the following raw materials in parts by mass: n-HA, PCL, CNW, PEG and n-HA degradation accelerator microcapsules; the implant prepared through the preparation method is excellent in mechanical property, has the performance of replacing an existing steel plate and an existing steel nail and is applied to bone repair, compared with natural degradation, the degradation rate is increased by 2.1 times, the degradation period of n-HA can be greatly shortened through the n-HA degradation accelerator micro-capsules, the situation that the difference between the degradation periods of PCL and n-HA is large is avoided, and the degradation efficiency of the implant is greatly improved. After the later-stage PCL degradation and implant material mechanical failure, the n-HA has a large number of residual particles, and bone remodeling is affected.

The present application relates to a kind of bone repair compositions and its preparation method, belong to biological medicine technical field, pharmaceutical composition includes acid anhydride bovine beta-lactoglobulin peptide, casein phosphopeptide, yak bone peptide, loquat leaf extract, pterostilbene, honeysuckle chlorogenic acid and cyperus rotundus extract;Acid anhydride bovine beta-lactoglobulin peptide is prepared using special enzymolysis method.Acid anhydride bovine beta-lactoglobulin peptide, casein phosphopeptide and yak bone peptide are loaded using carboxymethyl chitosan-hydroxyapatite composite microspheres, then using sodium alginate-sodium carboxymethyl cellulose containing loquat leaf extract, pterostilbene, honeysuckle chlorogenic acid and cyperus rotundus extract one coating, then using sodium alginate-sodium carboxymethyl cellulose secondary coating.The present application develops high-efficiency pharmaceutical combination component, using polymer material to coat drug to form sustained-release system, improve bioavailability, using granular carrier to increase the stability and solubility of drug, promote intestinal absorption, improve bone repair process.

The invention discloses a shapeable bone repair material capable of being implanted in a positioning manner and a preparation method thereof. The interior of the bone repair material is a core layer made of a gelatin, gallic acid and hydroxyapatite particle composite material, and the exterior of the bone repair material is a porous spongy collagen wrapping layer; the density of the wrapping layer is 20-100mg / cm < 3 >; the density of the core layer is 100-800 mg / cm < 3 >; and the particle size of the hydroxyapatite particles is 0.1-2 mm. The collagen sponge on the outer layer of the material wraps the gelatin / hydroxyapatite composite material, so that the problems of loose structure, weak binding force and displacement and powder falling after implantation of bone meal or collagen bone meal composite materials are solved, stimulation and trauma of bone meal particles to surrounding tissues can be avoided, and the conditions of bone meal discharge, bone grafting part collapse and the like are avoided. And in the self tissue regeneration process, the collagen component is degraded and absorbed, and the hydroxyapatite is fused with the new bone, so that bone regeneration is realized, and the success rate of tooth implantation can be improved.

The invention discloses a micron-sized gelatin-hydroxyapatite composite fiber material and a preparation method thereof. The preparation method comprises the following steps: (a) dissolving or dispersing gelatin in a volatile acid solution to obtain a gelatin solution; adding a cross-linking agent into the gelatin solution for in-situ cross-linking, and then adding hydroxyapatite nanoparticles for dispersion to obtain a mixed solution; the mass ratio of the hydroxyapatite nano particles to the gelatin is 0.30 to 1.50; (b) performing centrifugal spinning on the mixed solution, and drying to obtain a gelatin-hydroxyapatite composite fiber precursor; and (c) carrying out secondary crosslinking treatment on the gelatin-hydroxyapatite composite fiber precursor to obtain the gelatin-hydroxyapatite composite fiber material. The interference of HA particles on an electric field can be avoided, the uniformity of fibers is ensured, the production efficiency is higher, and the method is suitable for large-scale industrial production; by optimizing the formula of the mixed solution, the bone conduction performance of the composite fiber is effectively enhanced.

The invention discloses a porous oil-containing hydroxyapatite knuckle bearing surface preparation method based on electrochemical deposition, which is combined with surface texture design to improve the binding force of porous hydroxyapatite and is applied to a composite surface of a titanium alloy knuckle bearing. The method is specifically implemented according to the following steps that 1, the titanium alloy knuckle bearing micro-arc coating is prepared; step 2, surface texture design and laser etching; 3, hydroxyapatite is electrochemically deposited to form a porous liquid storage coating structure, and a hydroxyapatite composite lubricating interface is prepared on the outer surface of the inner ring of the knuckle bearing. The composite surface can improve the lubricating performance, the wear resistance and the storage and conveying capacity of lubricating liquid, and is particularly suitable for a knuckle bearing working under the conditions of high load, high speed and extreme temperature.

The invention provides a method for predicting the friction performance of a titanium alloy surface coating based on image features. The method comprises the following steps: preparing an electroplating solution; the Ti6Al7Nb titanium substrate is subjected to pretreatment; a titanium substrate is used as a cathode, a copper rod is used as an anode, and the copper and nano-hydroxyapatite composite coating is obtained through a jet electrodeposition process; collecting a coating surface image, and obtaining a coating surface friction coefficient through a friction test; extracting image features and carrying out normalization processing on test data; obtaining the most significant factors influencing the friction coefficient of the coating according to a grey correlation analysis method; and establishing a prediction model of the average friction coefficient with respect to image features based on a multiple regression algorithm, and performing reliability analysis. According to the method, the surface friction coefficient can be effectively predicted through the surface image features on the premise that the integrity of the titanium alloy coating is not damaged.

A biodegradable magnesium metal fixation pin for oral tissue fixation and its preparation method are disclosed. The fixation pin includes a pin head and a pin body. The entire fixation pin is made of 99.9-99.99% high-purity magnesium substrate, with no alloying elements added and an impurity content ≤0.01%. The surface of the fixation pin is sequentially coated with an oxide film layer and a polydopamine / hydroxyapatite composite coating. The oxide film layer has a thickness of 5-15 μm and a porous structure with pore sizes of 1-5 μm. The oxide film layer is prepared by a micro-arc oxidation process. The polydopamine / hydroxyapatite composite coating has a thickness of 10-20 μm, wherein the mass fraction of hydroxyapatite is 30-50%. This biodegradable magnesium metal fixation pin for oral tissue fixation features a reasonable structural design, excellent mechanical properties, and controllable degradation behavior.

The invention provides a magnesium alloy-hydroxyapatite composite bone prosthesis and a preparation method thereof.The preparation method of the magnesium alloy-hydroxyapatite composite bone prosthesis comprises the following steps that a target bone is scanned through CT, and a three-dimensional model containing an appearance structure and an internal structure is obtained; simplifying the appearance structure of the bone prosthesis, simulating an internal porous structure of the bone prosthesis, and designing a three-dimensional structure of the bone prosthesis; preparing hydroxyapatite printing slurry; printing a hydroxyapatite bracket by using a three-dimensional photocuring technology; carrying out cleaning, degreasing and high-temperature sintering on the hydroxyapatite scaffold; injecting molten magnesium alloy into the hydroxyapatite stent by using a pressureless permeation technology; and removing redundant materials by adopting a cutting tool, and grinding and polishing to obtain the magnesium alloy-hydroxyapatite composite bone prosthesis. The prepared magnesium alloy-hydroxyapatite composite auditory ossicle prosthesis has the advantages of being stable in positioning, not prone to shifting and disengaging, high in sound conduction efficiency, controllable in cost and capable of achieving personalized customization.

The present invention relates to a recombinant humanized type III collagen-hydroxyapatite composite bone repair material and its preparation method and application. At present, the industry has always expected to achieve efficient production of macromolecular humanized collagen or whole human collagen, which is a technical difficulty that is difficult to completely break through. The molecular weight of the recombinant humanized type III collagen of the present invention is close to that of natural collagen; at the same time, its encoding gene is optimized to achieve efficient and secretory expression of recombinant collagen with high yield. The composite bone repair material prepared with the collagen of the present invention has a more uniform microstructure than the products prepared with commercially available natural collagen or type III human collagen, and achieves the combination of hydroxyapatite grains and collagen fibers at the nanoscale. At the same time, there is a multi-scale pore structure inside the material, which achieves the purpose of better biomimetic natural bone composite material preparation. Therefore, this product can be widely used in dental (jaw) bone defects, as well as dental or bone surgery such as filling and repair of bone defects, nonunion, delayed bone healing or nonunion caused by various reasons, so that more patients can benefit from it.

The invention discloses a collagen and hydroxyapatite composite bone scaffold as well as a preparation method and application thereof, and relates to the technical field of bone scaffolds. The preparation method of the collagen and hydroxyapatite composite bone scaffold comprises the following steps: dissolving collagen in an acid solution to obtain a collagen solution with the concentration of 10-80 mg / L, mixing the collagen solution with hydroxyapatite, and stirring to obtain a compound; freeze-drying the compound, and cross-linking to obtain a primary product; washing the primary product with water to remove acid residues, and then freeze-drying to obtain the collagen and hydroxyapatite composite bone scaffold. The composite bone scaffold is spongy, has relatively high porosity, is beneficial to bone conduction and bone induction, is not easy to disintegrate and slag when being wetted, and is relatively good in supporting property.

The application relates to the field of anticorrosive coatings, in particular to an anticorrosive coating containing lanthanum cerium oxide and a preparation method thereof. The anticorrosive coating containing lanthanum cerium oxide comprises the following raw materials: 28-45 parts of ultraviolet stable type composite film forming substances, 5-10 parts of composite rare earth fillers, 6-12 parts of supported type synergistic antirust agents, 18-30 parts of mixed solvents, 0.8-2.5 parts of dispersants, 2.7-5.3 parts of functional additives and 0.5-1.2 parts of nano montmorillonite. The composite rare earth fillers are core-shell structure lanthanum cerium oxide-hydroxyapatite composite powders with lanthanum cerium oxide as the core and hydroxyapatite as the shell, and the shell thickness is 10-20 nm. The ultraviolet stable type composite film forming substances comprise epoxy resin and ultraviolet graft modified polyurethane with a weight ratio of 1: (0.6-2.2). The supported type synergistic antirust agent is a mixture of mesoporous silica loaded benzotriazole and zinc molybdate. The obtained coating has strong adhesion and long service life.

The invention belongs to the field of biomedical materials, and discloses a preparation method of a zinc phosphate / hydroxyapatite composite coating, which comprises the following steps: pretreating the surface of a titanium alloy; putting the pretreated sample into a conversion solution for galvanic induced chemical conversion; hydroxyapatite is sprayed on the surface of the conversion coating (transition layer zinc phosphate); according to the invention, zinc phosphate is used as a transition layer to spray hydroxyapatite, so that the bonding strength of the coating can be improved, and the hydroxyapatite layer is prevented from peeling off. The preparation process is simple, quick, simple and convenient to operate and easy to popularize and apply.

The application provides a multilayer polymer biomimetic membrane for dura mater repair and a preparation method thereof. The biomimetic membrane comprises a three-layer biomimetic nanofiber composite structure: a cell adhesion inner layer on the side facing the brain tissue, an anti-adhesion outer layer on the side facing the skull, and an intermediate reinforcing layer between the cell adhesion inner layer and the anti-adhesion outer layer. The cell adhesion inner layer is a PCL / chitosan / collagen composite fiber layer, the intermediate reinforcing layer is a PCL / hydroxyapatite composite fiber layer, and the anti-adhesion outer layer is a PCL / polylactic acid-hydroxyacetic acid copolymer (PLGA) layer. The method comprises cell adhesion inner layer preparation, intermediate reinforcing layer preparation, anti-adhesion outer layer preparation, and continuous production processing. The application obtains a multilayer artificial dura mater with strong interlayer bonding, high adhesion, and biomimetic mechanical properties.

The invention relates to a hydroxyapatite injection and a preparation method thereof, belongs to the field of bionic bioremediation materials, and particularly relates to a self-assembled polypeptide, a nano-scale hydroxyapatite composite injection and a preparation method thereof, the hydroxyapatite which can be used for injection is obtained by modifying and compounding hydroxyapatite. The composite material has the advantages of injectable permeability, strong biomimetic mineralization capability, cell adhesion promotion and the like, overcomes the defects of microsphere fillers in the prior art, and has a remarkable bone repair promotion effect and a good clinical application prospect.

The invention belongs to the technical field of catalysts, and particularly relates to a metal palladium immobilized hydroxyapatite composite catalyst as well as a preparation method and application thereof. A solution impregnation method is adopted, hydroxyapatite serves as a solid carrier, metal palladium serves as an active component, a hydroxyapatite solution and a palladium salt solution are heated in a water bath at the temperature of 40-80 DEG C, so that the metal palladium is fixed to the hydroxyapatite, and the metal palladium immobilized hydroxyapatite composite catalyst is obtained. The prepared metal palladium immobilized hydroxyapatite composite catalyst is high in catalytic activity and easy to recycle and reuse, and has efficient adsorbability and selective activity when being applied to dehydrogenation self-coupling reaction of styrene. The preparation method is simple, convenient and easy to operate, the process complexity and the production cost are reduced, and industrial large-scale production is facilitated.

The invention discloses a degradable composite polyethylene plastic and a preparation method thereof in the field of plastic technology. The degradable composite polyethylene plastic comprises the following components in parts by weight: 80-100 parts of low-density polyethylene, 8-12 parts of starch, 5-8 parts of dopamine-modified microcrystalline cellulose, 10-15 parts of polyetheretherketone / hydroxyapatite composite material, 15-20 parts of chitosan / nano-silica aerogel, 2-3 parts of polyethylene wax, and 3-5 parts of glycerol. The invention proposes that dopamine-modified microcrystalline cellulose, polyetheretherketone / hydroxyapatite composite material and chitosan / nano-silica aerogel are added to polyethylene to improve the degradability and mechanical properties of polyethylene plastic.

The present invention relates to a silk fibroin / hydroxyapatite composite material, and a preparation method therefor and an application thereof. A uniform mixture of hydroxyapatite nanoparticles, silk fibroin, and hexafluoroisopropanol is maintained at a temperature range from 50° C. to 60° C. for at least 1 hour to obtain a silk fibroin / hydroxyapatite solution; the silk fibroin / hydroxyapatite solution is poured into a long cylindrical mold, two ends of the long cylindrical mold being respectively an end A and an end B; at room temperature, the end A is opened and the end B is closed, and the mold is vertically immersed in methanol with the opening facing up and let stand for at least 2 days; the mold is turned upside down, the end A is closed and the end B is opened, and the mold is vertically immersed in the methanol with the opening facing up and let stand for at least 2 days; the mold is removed, and ventilation and drying are performed to obtain a silk fibroin / hydroxyapatite composite material. The silk fibroin / hydroxyapatite composite material prepared in the present invention has uniform strength, good mechanical properties, and significant osteoinductivity.

The invention relates to a chiral hydroxyapatite composite biological material with a multilayer structure as well as preparation and application of the chiral hydroxyapatite composite biological material. The biological material is prepared from a CS / CA-CMHAP composite scaffold and silver ions (Ag < + >) loaded on the CS / CA-CMHAP composite scaffold, wherein the CS / CA-CMHAP composite scaffold is obtained by compounding CS, CA and a hydroxyapatite nanosheet CMHAP. Compared with the prior art, the biological material provided by the invention has a remarkable healing promoting effect on old-age infected skin wounds in an in-vivo experiment, and can effectively reduce inflammatory response, promote tissue regeneration and the like by regulating and controlling an immune microenvironment.