37 results about "Bone graft materials" patented technology

The utility model discloses an absorbable net-shaped device for fixing bone grafting materials, and relates to the technical field of medical oral cavity, the absorbable net-shaped device comprises a woven net and bone nails, the woven net is made of absorbable biological materials, tightening ropes are arranged at four corners of the woven net, and each tightening rope is correspondingly wound on one bone nail. The bone nail is rotationally nailed into the dentale, the woven net is tightened to fix the bone grafting material, meanwhile, the woven net is an absorbable biological material and does not need to be taken out through a special operation in the later period, and the pain of a patient and the medical burden are greatly relieved.

[Solution] An expandable intervertebral spacer system has upper and lower plates forming a cage. The top, bottom, and sides of the cage have openings for receiving bone graft material. At least one angled section extends from the upper or lower plate into the cage. The upper and lower plates are connected to each other by a hinge at the proximal end of the cage. The cage is expanded by inserting a push rod from the proximal end of the cage against the angled section, forcing the upper and lower plates apart at a desired angle. A locking mechanism at the distal end of the cage uses a ratcheting mechanism to secure the plates apart. In this ratcheting mechanism, a torsion spring biases a movable strut against a fixed strut, which cooperates with sawtooth engagement on the movable and fixed struts to secure the upper and lower plates apart.

The utility model relates to the technical field of medical instruments, in particular to a bone graft material forming and cutting device. A bone graft material forming and cutting device comprises a shell, an observation plate, a sealing door, guide plates, a loading frame, a first electric sliding rail and the like, a hollow cavity is formed in the shell from the left side to the middle, the observation plate is installed on the front side of the shell, the sealing door is rotationally connected to the left side of the shell, and the guide plates are fixedly connected to the bottom of the cavity in a bilateral symmetry mode; a loading frame is slidably connected to the upper portion of the guide plate, and first electric sliding rails are installed on the rear side wall of the cavity in a bilateral symmetry mode. A three-dimensional motion system composed of the first electric sliding rail, the second electric sliding rail and the third electric sliding rail is arranged, automatic control is achieved in cooperation with the controller, the high-precision non-contact cutting effect on bone graft materials is achieved, the closed design is adopted, the pollution risk possibly caused by traditional mechanical cutting is reduced, and the cutting efficiency is improved. And the quality and the safety of the material are ensured.

The invention relates to a preparation method of a plastic bone grafting material and the plastic bone grafting material.The preparation method comprises the following steps that a, phenyl phosphate lithium salt is dissolved in a phosphoric acid buffer salt solution to obtain a mixed solution, and Ge MA is dissolved in the mixed solution to obtain a Ge MA gel solution; b, bone meal and the Ge MA gel solution are subjected to a cross-linking effect, so that the bone meal and the Ge MA gel solution are fully mixed, then light source irradiation is conducted, the bone meal hydrogel bone grafting material is obtained, and the particle size of the bone meal is 0.25-0.5 mm. According to the preparation method of the plastic bone grafting material, provided by the invention, the bone meal and the Ge MA gel solution are subjected to cross-linking and then subjected to light source irradiation, so that the bone meal and the hydrogel are uniformly mixed, the compatibility of an organic phase and a bone meal particle interface is good, and the prepared plastic bone grafting material is relatively high in plasticity and good in osteoinductivity; and the cell adhesion rate is high.

One embodiment of the present specification provides a method for preparing a low-crystallinity calcium phosphate-based antibacterial bone graft material, comprising the steps of: (a) adding a calcium precursor and a phosphate precursor at one time to synthesize calcium phosphate; (b) putting the calcium phosphate into an antibacterial substance precursor solution to react; (c) a step of freeze-drying the product of step (b); (d) a step of mixing the product of step (c) with a shape control agent and performing press molding to prepare a molded body; and (e) a step in which the shape control agent of the molded body is removed in a solvent having a temperature equal to or higher than the boiling point and then dried.

The invention discloses a digital auxiliary PRF bone meal complex preparation method applied to periodontal minimally invasive surgery, belongs to the technical field of PRF bone meal complex preparation, and overcomes the defects that in the prior art, PRF bone meal complex and minimally invasive surgery combination is ineffective, and MIST curative effect improvement is limited due to poor adaptability of bone grafting materials. The method comprises the following steps: constructing a matched three-dimensional oral cavity model according to multi-source oral cavity data of a patient; reconstructing and cutting the three-dimensional oral cavity model to obtain an operation area surface data model; performing optimization and manufacturing adaptation processing on the surface data model of the operation area to obtain a three-dimensional digital model of the subbony pocket form female die; according to the three-dimensional digital model, preparing a subosseous pocket form female die, and preparing the PRF bone powder complex matched with the subosseous pocket in the subosseous pocket form female die.

The invention discloses a traditional Chinese medicine ingredient modified bone graft material and a preparation method thereof, and relates to the technical field of bone graft materials. The feed additive is prepared from the following raw materials: calcined bone meal and a traditional Chinese medicine extract, the traditional Chinese medicine extract comprises a radix salviae miltiorrhizae extract and / or a radix scutellariae extract. The preparation method comprises the following steps: preparing calcined bone meal, preparing simulated body fluid and preparing the modified bone graft material. The product material can be applied to a dental bone grafting material. The traditional Chinese medicine extract is loaded on the bone material, and the bone material is modified, so that the bone graft material with good biocompatibility, osteogenesis promoting capability and better osteogenesis induction potential can be obtained.

The utility model provides an interbody fusion cage which comprises a body and threads formed on the outer surface of the body, and is characterized in that the interbody fusion cage is provided with an opening groove used for containing bone grafting materials, the opening groove is spirally arranged along the outer surface of the interbody fusion cage, the interbody fusion cage comprises a front end portion and a rear end portion, the front end portion is in a circular truncated cone shape, and the rear end portion is in a circular truncated cone shape. The rear end part is cylindrical, the threaded teeth of the front end part are provided with front end threaded tooth tips pointing to the front end, and the threaded teeth of the rear end part are provided with rear end threaded tooth tips pointing to the rear end. Therefore, the correct distance between the upper vertebral body and the lower vertebral body is guaranteed, and meanwhile bony fusion between the vertebral bodies is effectively promoted.

Disclosed herein are components, systems, and methods delivery bone graft material to a treatment site. Specifically, embodiments of a bone graft delivery system are disclosed that include a cannula defining a lumen, and a sled defining a channel. A first portion of the sled forms a lateral opening extending into the channel perpendicular to a length of the sled, and a second portion of the sled includes an injector coupler. The sled is operably couplable to the cannula such that the first sled portion is positioned within the lumen and the second sled portion is positioned outside the lumen. Embodiments of the bone graft delivery system include a plunger sized to be insertable into the lumen through the channel, and a push step that slidably receives the plunger. Also disclosed are methods of use of the bone graft delivery system.

A maxillofacial device includes a substructure with a shape that is custom made to a patient's maxillofacial area; a framework coupled to the substructure, the framework and substructure being made of a single continuous material or a combination of materials, the framework having a plurality of grid elements; and one or more plate fixations coupled to the substructure. The framework has a shape that is custom made to fit the patient's maxillary sinus area. The framework is configured to be surrounded by a bone graft material, wherein the substructure and framework provide rigidity and stiffness for the bone graft material.

A system for performing posterior spinal fusion at a zygopophyseal joint comprises an implant device (1) and a fixture device (2) thereof. The implant device (1) is in the form of an element comprising an opening (12) for receiving bone graft material, intended to be inserted into a pre-prepared lacuna (5) at a zygopophysis joint to be fixed, while the fixation device is in the form of a transarticular screw (2) for pressurizing the implant device (1) in the lacuna, comprising a threaded distal end portion (20) intended to be screwed into at least the bone material (3) downstream of the implant device (1), the proximal end portion (21) of which is shaped to abut against or be screwed into the bone material (4) upstream of the implant device (1).

Provided herein are formulations for treating bone graft materials prior to implantation. Treating the bone graft materials with the formulations disclosed herein can restore the physiological and biochemical characteristics of bone. The bone graft can be a bone allograft. Also provided herein are methods for preparing the formulations and methods for preparing a bone graft for transplantation.

Disclosed are a method and an apparatus for examining bone formation of alveolar bone using an oral scanner having a tomographic function. The bone formation inspection method for alveolar bone comprises: a step of filling a bone graft material into an alveolar bone to be subjected to bone graft, suturing gingiva, and then acquiring a surface shape image of a portion where the alveolar bone is formed by using a surface shape acquisition optical system; a step for acquiring an internal cross-sectional image showing the state of the alveolar bone and the bone graft by means of an internal cross-sectional acquisition optical system at a predetermined position in the acquired surface shape image; a step of moving the oral scanner to acquire a gingival surface shape after a predetermined period of time has elapsed, and when the gingival surface shape at a position at which the internal cross-sectional image was previously acquired is detected, acquiring an internal cross-sectional image showing the state of the alveolar bone and the bone graft at the position using an internal cross-sectional acquisition optical system of the oral scanner; and a step for comparing the internal cross-sectional images acquired at predetermined intervals.

The present application relates to the technical field of orthopedic surgery, more specifically to a drilling and bone scraping device used in the transpedicular approach and a method for using the same; the method is: verifying the puncture position under fluoroscopy during the operation; connecting the inclined angle connector in the operating room, gradually expanding the bone channel by adjusting the drilling and bone scraping device; using the drilling and bone scraping device with different angles to reach the intervertebral space through the bone channel, and preferentially scraping off the hardened bone; controlling the drilling and bone scraping device and the drilling guard frame to align the position for drilling or scraping the bone channel; blocking the foreign matter around the drilling position by the drilling guard frame, recycling the bone debris during the drilling process, and completing the drilling of the bone channel; placing the funnel designed into the target intervertebral space through the bone channel, and knocking the bone graft material into the intervertebral space; the present application solves the problem of being unable to automatically punch at a specified angle and depth during the transpedicular approach.

The invention relates to an injectable (not requiring pre-molding), biodegradable, and porous high internal phase emulsion composition prepared using solvent-free, photo- crosslinkable, low molecular weight, three-arm polycaprolactone methacrylate-based high internal phase emulsions (3PCLMA HIPE) for use as a bone graft, and to the method for preparing the same. The composition according to the invention is produced using the emulsion templating technique.

A bone graft delivery kit includes a hollow tube having a proximal end and a distal end, an implant and a plunger. The hollow tube is configured to be connected to the implant, and to convey bone graft material to a graft receiving area in a patient. The plunger is configured to facilitate moving the bone graft material through the hollow tube. The implant includes openings configured for passage of the bone graft material therethrough, and internal ramps configured to direct the bone graft material to the openings.

A bone graft material includes a shielding film configured to cover an upper surface of a bone defect and separate the bone defect from an external environment and impregnated with a bone morphogenetic protein-2 (BMP-2) solution, and a filler that contacts a lower surface of the shielding film and is configured to fill the bone defect. The bone graft material is designed such that, by impregnating the BMP-2 solution into the shield film so as to form a bone cover of the bone defect, and the filler at the bottom of the shield film can sufficiently form bone in the cover.

The invention discloses an intelligent control system and method for the sterilization process of a bone graft material, and the system comprises a heating / cooling module which is used for heating or cooling a heating cavity according to the instruction of a control module; the temperature sensor module is used for monitoring the temperature of the heating cavity and the interior; the control module comprises a processor and a memory, a computer program is stored in the memory, and the processor is configured to execute the computer program to realize the following steps: system self-inspection; detecting whether the sterilization container is in place in the heating cavity; executing an intelligent sterilization program, wherein the program at least comprises a heating stage, a constant temperature stage based on a preset target core temperature and the shortest holding time, and a cooling stage; automatically recording sterilization process data and generating a sterilization protocol; safety monitoring and alarming are provided; the man-machine interaction module is used for displaying the system state, parameters and alarm information and receiving a user instruction; and the data output module is used for outputting a sterilization protocol and process data.

This invention provides a novel bone graft retention structure that can securely fix the bone graft material during the healing period, and during or after the healing period, the bone graft fixing component is safely absorbed into the body through a bioabsorption reaction without the need to remove it from the body through additional surgery, and is then safely excreted from the body. [Solution] A holding structure for granular material, wherein the granular material is a bone graft material in the shape of fine particles that fill the gap between the root of an implant embedded in the living body and the bone of the living person opposite the root, and a mesh-like material having a mesh structure holds and fixes the bone graft material in all directions.

A decortication and grafting device for lumbar fusion procedures includes a distal decortication tip and a tubular portion extending to a proximal handle. The tubular portion is configured to receive and allow passage of a bone graft material therethrough. A graft injection device coupled to the proximal handle of the decortication and grafting device injects graft material into the tubular portion which is then deposited on a bony surface decorticated by the decortication tip. A system for decortication and grafting further includes an access portal device defining a first lumen configured to slidably couple to an anchor device, such as a k-wire, and a second lumen configured to accommodate passage of various surgical instruments, such as a dilation device and the decortication and grafting device, and guide the instruments to a targeted surgical site.

A transparent bone grafting funnel is directly arranged in a protective sheath in the endoscopic surgery bone grafting step, the transparent bone grafting funnel comprises a bone grafting part and a bone grafting push rod which is used for being matched with the bone grafting part and can pass through an inner hole of the endoscope, and an opening matched with the intervertebral space in size is formed in the bottom of the bone grafting part. The bone grafting part comprises a first bone grafting part, the first bone grafting part comprises a first pipe body, one end of the first pipe body is connected with a first funnel, and the first pipe body and the first funnel are integrally formed. And placing the prepared small bone graft into a bone graft funnel, and pushing the bone graft or bone graft material into the intervertebral space of the spine by using a bone graft push rod under direct view.

Methods and apparatus are disclosed for distracting tissue. The devices and methods may include insertion of first and second elongated members into the space between two tissue layers, with an augmenting elongated member inserted therebetween to form a distraction device between the tissues to be distracted. The distraction device defines a generally annular configuration, with a locking member secured to one of the elongated members at a plurality of locations to maintain the distraction device in the generally annular configuration. The augmenting elongated member may be shorter than the first and second elongated members such that a window is defined between the proximal and distal ends of the augmenting elongated member when the distraction device and the first and second elongated members are in the generally annular configuration. Bone graft material or bone filler may be introduced into the interior of the distraction device through the window.

Embodiments herein are generally directed to spinal implants, systems, apparatuses, and components thereof that can be used in spinal fusion and / or stabilization procedures, as well as methods of installation. The spinal implants may be expandable. In some embodiments, the spinal implants may be configured to be backfilled with bone graft material after insertion.

The invention discloses bone transplantation minimally invasive equipment and a bone taking method thereof, and belongs to the field of medical instruments. The hollow drill bit is used for drilling bone tissue, meanwhile, the drilled bone tissue and bone marrow are collected through negative pressure suction, the purpose of fully automatically obtaining autogenous bone and bone marrow through a minimally invasive channel is achieved, and effective separation and independent collection of solid bone tissue and bone marrow are achieved. According to the invention, the drilled bone tissue material is directly adsorbed and collected into the first collecting cavity under negative pressure, so that mechanical damage and thermal damage to the bone tissue in the process of collecting and conveying the bone tissue material by adopting a spiral conveying mechanism and other mechanical mechanisms are avoided. According to the bone taking method implemented by adopting the bone transplantation minimally invasive equipment, effective bioactive components such as stem cells and growth factors in the separated bone marrow can be quickly enriched in artificial bones or autogenous bones in the process of obtaining bone transplantation materials, so that the biological activity of the artificial bones or the autogenous bones is achieved; the synchronous implementation of the biological activity recovery of the artificial bone and the acquisition of the bone tissue material is realized.

An expandable interbody spacer for spinal fusion includes opposing upper and lower end plates. An actuator moves the upper and lower end plates heightwise relative to one another to expand the height of the expandable interbody spacer. An end plate fastener secures the upper and lower end plates to one another and enables the upper and lower end plates to heightwise move relative to one another. The upper and lower end plates and the at least one end plate fastener are integrally formed as a single, one-piece, monolithic component. An expandable interbody space may include upper and lower end plates with overlapping anterior and posterior walls that define openings in communication with an internal chamber. An expandable interbody spacer may include a barrel nut defining a window to enable bone graft to pass therethrough and into an internal chamber.

The present invention relates to a two-stage sintering method for preparing a porous biphasic calcium phosphate ceramic from calcium-containing biological waste, wherein hydroxyapatite prepared from calcium-containing waste is mixed with a foaming agent to prepare a bone graft material having medicinal use through two-stage sintering.

The application discloses a preparation method of a deer antler-DCB@EVsABPCs bone graft material, and specifically comprises the following steps: step 1, preparing an Antler-DCB support; step 2, preparing a 10% HAMA hydrogel and ABPCs-EVs; step 3, mixing; step 4, taking the Antler-DCB and immersing it into the HAMA hydrogel containing the ABPCs-EVs; and step 5, exposing to 405 nm ultraviolet light for 30 seconds to obtain the bone graft material. The application further discloses the deer antler-DCB@EVsABPCs bone graft material. The deer antler-DCB@EVsABPCs bone graft material and the preparation method thereof disclosed by the application have a strong ability to regulate osteogenesis, angiogenesis, neurogenesis and immune response, thereby providing a potential therapeutic intervention measure for treating serious bone defects.

The utility model discloses a total endoscopic fusion cage device for bone grafting. The total endoscopic fusion cage device comprises a pushing and injecting part, an injecting part and an injecting outer shell which are sequentially connected in a sleeved mode from inside to outside. The injection part and the injection outer shell are detachably connected through a connecting part; the injection device further comprises a retractable embedded bag body which is detachably connected with the injection outer shell body. The injection part comprises a first injection part and a second injection part which are sequentially matched with the injection outer shell for use, and an open hole matched with the filling opening of the embedded bag body is formed in the side face of the top of the first injection part; the top end of the second injection part is of an opening structure; the injection outer shell is provided with a side opening and a top opening which are matched with the first injection part and the second injection part respectively. According to the embedded capsule structure, the embedded capsule structure can be unfolded through implantation of pushing and injecting bone cement, the bone cement is matched with the embedded capsule to be implanted into gaps of vertebral bodies, accurate control over implementation positions and angles is achieved, and the technical requirement for uniform distribution of bone grafting materials is met.

The present invention relates to a method of preparing a bone graft composition, comprising the steps of: (1) preparing a bone morphogenetic protein solution by mixing a solvent and a bone morphogenetic protein; (2) mixing the bone morphogenetic protein solution with porous bone graft material powder having an average particle diameter of 200 μm to 5,000 μm, and performing centrifugal separation using a refrigerated centrifuge in a cold temperature state of 5°C or less to cause the bone morphogenetic protein to be physically adsorbed to the surface or inside the pores of the porous graft material powder; (3) mixing and stirring 1 part by weight of the graft material powder having the bone morphogenetic protein adsorbed thereto and 0.3 parts by weight to 3 parts by weight of hydroxypropyl methylcellulose powder based on 1 part by weight of the graft material powder to form a gel; and (4) forming a sponge-like structure in which the graft material powder is fixed within a high-molecular network formed by the hydroxypropyl methylcellulose by freeze-drying the gel under vacuum.

A method for examining alveolar bone formation includes filling an alveolar bone with a bone grafting material, suturing gums so as to cover the bone grafting material, and then obtaining a surface shape image using a surface shape acquisition optical system; obtaining an internal cross-sectional image showing a state of the alveolar bone and the bone grafting material at a predetermined location of the obtained surface shape image; obtaining an internal cross-sectional image showing the state of the alveolar bone and the bone grafting material at a corresponding location when a gum surface shape at the location where the internal cross-sectional image was previously obtained is detected while obtaining gum surface shapes by moving the intraoral scanner after a predetermined period has elapsed; and comparing the internal cross-sectional images obtained at a predetermined time interval.