40results about How to "Promote bone fusion" patented technology

A pair of flat support plates in a spinal fusion implant device contact and rest against the softer, central cancellous bone portion of respective endplates of adjacent vertebrae. Each support plate has a front template that is orthogonal to the plate and is bent to communicate with the anterior surface of the hard cortical endplate the vertebrae. A wedge-shaped support strut in a central channel between the two plates is configured to vary the distance between the support plates such that the height of the device proximate the anterior end is greater than the height of the device at the posterior end to maintain the natural lordosis of the spine. Channels formed on either side of the support strut are filled with bone graft material and contact the endplates of the vertebrae through large openings in the flat support plates to facilitate fusion.

This invention relates to a spinal implant for promoting fusion of adjacent vertebrae and restoration of normal disc height. The spinal implant includes an upper and lower surface adapted to engage cancellous bone tissue in the vertebral bodies. The spinal implant also includes at least two opposing bearing surfaces adapted to bear against cortical bone tissue in the endplates of adjacent vertebrae. This invention also provides an instrumentation to prepare the intervertebral space to receive the spinal implant and techniques for treating patents in need of corrective spinal surgery.

A multi-density polymeric interbody spacer formed from biocompatible material for osteoconductivity includes multiple density regions of different porosity to provide both strength and osteoconductivity. An interface region is formed between the density regions to provide both direct adhesion and mechanical interlocking between the different density regions to increase the strength of the multi-density polymeric interbody spacer. A method for forming the multi-density polymeric interbody spacer includes curing a first density region to achieve a first target porosity. A second density region may then be molded to the first density region to achieve a second target porosity. A portion of the second density region partially flows into pores of the first density region, providing direct adhesion and mechanical interlocking between the first and second density regions.

An improved technique for spinal fusion including administration of an HMG-CoA reductase inhibitor to the fusion site. The HMG-CoA reductase inhibitor is preferably delivered to the site by a carrier. More preferably, the HMG-CoA reductase inhibitor is delivered to the site by a noncompressible delivery vehicle. The invention is suitable for promoting non-anatomic or heterotopic bone growth between any bony surfaces where bone growth is desired but does not naturally occur.

A multi-density polymeric interbody spacer formed from biocompatible material for osteoconductivity includes multiple density regions of different porosity to provide both strength and osteoconductivity. An interface region is formed between the density regions to provide both direct adhesion and mechanical interlocking between the different density regions to increase the strength of the multi-density polymeric interbody spacer. A method for forming the multi-density polymeric interbody spacer includes curing a first density region to achieve a first target porosity. A second density region may then be molded to the first density region to achieve a second target porosity. A portion of the second density region partially flows into pores of the first density region, providing direct adhesion and mechanical interlocking between the first and second density regions.

A hollow non-load-bearing spinal implant having a hollow body and an attachment device for attaching the implant. A method of inserting a non-load-bearing spinal implant by inserting the laminoplasty implant into a prepared space in a spine, positioning the implant within the prepared space and affixing the implant to the spine.

The invention discloses a suspended customized assembly total sacrum prosthesis and a customization method. The suspended customized assembly total sacrum prosthesis comprises a prosthesis body, a right ilium wing fastener and a left ilium wing fastener. The suspended customized assembly total sacrum prosthesis has the advantages that the suspended customized assembly total sacrum prosthesis can rapidly promote bone cell generation and bone fusion, restore sacrum functions and achieves reconstructed waist sacroiliac joint stability.

The interverterbral fusion implement for cervical vertebra anterior operation is one hollow column with polygonal or circular cross section, holes on side wall and sharp teeth on the upper and the lower surfaces. It is made of polymer material capable of being absorbed by human body, poly(DL-lactic acid), poly(L-lactic acid), polyglycolic acid or their copolymer. It has determined early-stage locking effect, late-stage bone fusion effect, good biocompatibility and proper mechanical structure, and may be self-degraded after being fused with vertebra. It results in no rejection and may be also used in thoracic vertebra and lumbar vertebra operation.

A method for performing a spinal fusion procedure between the transverse processes of two adjacent vertebra is disclosed. The method includes creating a vascularized bone flap at each of the transverse processes and introducing a bone graft delivery device to the site between the transverse processes and the vascularized bone grafts. A novel bone graft delivery system and device is also disclosed.

The invention discloses an anterior cervical interbody fusion cage which comprises a main body and a development needle arranged on the main body, wherein the main body is a hollow tetrahedron; the cross section of the hollow periphery of the tetrahedron is ladder-shaped; the cross section of the hollow inner circumference of the tetrahedron is square or rectangular; the main body comprises a front wall, a rear wall, a left side wall and a right side wall; and the front wall is connected with the rear wall through the left side wall and the right side wall. The shape of the main body confirms to the anatomic form of the cervical intervertebral disc of a normal human body; while the safe implantation is ensured, the main body can be in tight contact with end plates of an upper cervical vertebral body and a lower cervical vertebral body under the compression state to create a good condition for bone fusion; and the cross section of the hollow inner circumference of the main body is square or rectangular, so that the contact surface of the main body and the end plates of the cervical vertebral bodies is increased to the greatest extent, the bone implementation amount is increased, and the fusion is speeded up.

A pair of flat support plates in a spinal fusion implant device contact and rest against the softer, central cancellous bone portion of respective endplates of adjacent vertebrae. Each support plate has a front template that is orthogonal to the plate and is bent to communicate with the anterior surface of the hard cortical endplate the vertebrae. A wedge-shaped support strut in a central channel between the two plates is configured to vary the distance between the support plates such that the height of the device proximate the anterior end is greater than the height of the device at the posterior end to maintain the natural lordosis of the spine. Channels formed on either side of the support strut are filled with bone graft material and contact the endplates of the vertebrae through large openings in the flat support plates to facilitate fusion.

The invention discloses a porous titanium interbody fusion cage. The porous titanium interbody fusion cage is a structural component, and titanium alloy materials are integrally printed by the aid of a 3D (three-dimensional) printer to form the structural component. The porous titanium interbody fusion cage comprises a support structure and a pore structure. The support structure is used for bearing external load, and the pore structure is used for guiding new bone ingrowth. The volume of the support structure ranges from 5% to 20% of the total volume of the porous titanium interbody fusion cage. The pore structure is outwardly exposed on the upper side, the lower side, the front side, the rear side and the right side of the porous titanium interbody fusion cage in an open manner, and open growth spaces can be provided for effective growth of bones and the like. The porous titanium interbody fusion cage has the advantages that laser power, the scanning speeds and the scanning interval are controlled when a method for preparing the porous titanium interbody fusion cage is implemented, and accordingly the porous titanium interbody fusion cage can be integrally formed, has appropriate pore diameters and is high in porosity and good in strength; functions of two functional components of the porous titanium interbody fusion cage can be independently implemented by the functional components, the two functional components further can be matched with each other, and accordingly interbody therapy effects can be realized.

The invention provides a multi-hole tantalum rod, and belongs to the technical field of human implant materials. The multi-hole tantalum rod comprises a threaded portion and a multi-stage hole portion, wherein three-dimensional circular holes penetrate through the threaded portion and the multi-stage hole portion; the apertures of the circular holes are distributed in a gradient mode from small tolarge from the threaded portion to the multi-stage hole portion. The multi-hole tantalum rod prepared by a 3D printing process of powder bed melting is provided with the circular holes distributed inthe gradient mode; the multiple holes in the tantalum rod are distributed uniformly and are controllable, so that bone conduction and bone fusion are promoted; the hole structure and the mechanical properties such as elasticity modulus are adjustable, so that the property is much closer to human skeletal property. According to data of the embodiment, the multi-hole tantalum rod has a compressionstrength of 120-180 MPa, an elasticity modulus of 10-20 GPa, and a porosity rate of 75-85%.

The invention provides a posterior cervical single-door bone plate which comprises a body, a first end, a second end and a middle portion. The middle portion is connected with the first end and the second end, the first end and the second end are respectively provided with a through hole used for installing a fixing element, and the middle portion is provided with a long through hole used for containing a screw in the length direction. By means of the posterior cervical single-door bone plate, an open vertebral plate in laminoplasty can be fixed and is prevented from being closed again. The posterior cervical single-door bone plate is simple in structure and convenient and quick to operate.

The invention discloses a pore structure part of a porous titanium intervertebral fusion cage. The pore structure part is a part of a fusion cage printing forming titanium alloy material integrally through a 3D printer, and is used for leading new bone ingrowth. The pore structure part is composed of pore units of a regular tetrahedron structure; respective one ends of four titanium columns of each pore unit are connected together, the inclined angle between each titanium column and another is 109 degree 28 cent, meanwhile the other end of each titanium column is connected to the other end of one titanium column of a corresponding adjacent pore unit, and the inclined angle between the titanium columns is 109 degree 28 cent as well, that is the connection method of each titanium column of the pore structure part and the adjacent titanium column is arranged according to a method similar to the arrangement method of the chemical bond between each carbon atom and an adjacent carbon atom in diamond. The provided pore structure part of a porous titanium intervertebral fusion cage is good in intensity, and has certain elasticity and a certain intervertebral healing effect when in use.

The invention relates to a novel degradable bone implantation material and a preparation method thereof. The bone implantation material is prepared by mixing and pressurizing powder and liquid and then performing solidification, wherein the powder is prepared from 32-70% by weight of phosphate, 28-65% by weight of metal oxide and 1-15% by weight of a silicon-containing compound, and the liquid-solid ratio of the liquid and the powder is 0.1-0.5 ml / g. The preparation method comprises the following steps that firstly, the powder and the liquid are mixed and stirred according to the ratio of 0.1-0.5 ml / g to obtain paste; secondly, the paste is injected into a mould, the pressure is kept to be greater than or equal to 5 atm; thirdly, after the paste solidifies and is released from the mould, the bone implantation material is obtained; finally, the bone implantation material is put in a constant-temperature constant-humidity cabinet with the temperature of 37 DEG C and the humidity of 50-100% for 24 hours or more. The bone implantation material has the advantages of being high in strength, degradable, absorbable, controllable in degradation rate, high in bony fusion rate and the like.

The invention discloses a portion of a porous titanium interbody fusion cage, namely a supporting structure portion of the porous titanium interbody fusion cage. The supporting structure portion is used for bearing external load; and a pore structure portion is used for guiding in-growth of new bone. The upper side, the lower side, the front side, the rear side and the right side of the supporting structure portion are exposed outwards in an open mode, and the front side, the rear side and the right side are provided with open spaces in the form of triangular prisms. When the supporting structure portion is applied to the porous titanium interbody fusion cage, the pore structure portion, which is matched with the supporting structure portion, is exposed outwards in an open mode at the upper side, the lower side, the front side, the rear side and the right side of the cage, so that open growth spaces are provided for the effective growth of bone substances and the like. The supporting structure portion of the porous titanium interbody fusion cage provided by the invention can independently perform functions thereof; and in addition, the supporting structure portion, which is matched with the pore structure portion, can achieve an effect of conducting intervertebral treatment.

The invention discloses an intervertebral fusion device with bone ingrowth micropores for lumbar vertebrae. The fusion device includes a fusion device body of a tetrahedral structure with a rectangular cross section, wherein the fusion device body is defined by connecting a front device wall, a left device wall, a rear device wall and a right device wall in sequence; the upper end surfaces of theleft device wall, the rear device wall and the right device wall are provided with jagged grooves, and the bone ingrowth micropores are vertically formed in the bottoms of the jagged grooves; the upper end surface of the front device wall is provided with multiple through holes, and the middle of the front end surface is provided with a threaded hole; the interior of a device wall at the junctionbetween the left device wall and the rear device wall and the interior of a device wall at the junction between the right device wall and the front device wall are provided with developing needles. Polyether-ether-ketone materials are used, bone implanting windows and the developing needles are designed, the micropores for bone ingrowth components are added, and the developing needles are used fordisplaying the implanting position of the fusion device under an X ray; during an operation, by implanting the bone ingrowth components identical with the micropores in diameter in the bone ingrowthmicropores for artificial bone induction, the bone fusion on supported surfaces can be improved, the intervertebral fusion areas are increased, and the function of improving the stability of a vertebrae after the intervertebral fusion operation is achieved.

The invention discloses an intervertebral fusion machine with bone ingrowth millipores for cervical vertebra. The fusion machine comprises a machine body of which the cross section is in a sector shape, wherein the machine body is defined in the mode that a front machine wall, a left machine wall, a back machine wall and a right machine wall are connected in sequence and is of a tetrahedron structure; a circle of a trapezoid groove with a wide upper portion and a narrow lower portion is formed in the upper end surface of the machine body, a plurality of vertically arranged bone ingrowth millipores are formed in the groove bottom of the groove, and threaded holes are formed in the middle of the back machine wall; developing needles are arranged on the junction portion of the left machine wall and the back machine wall and the junction portion of the back machine wall and the right machine wall and arranged in the machine wall of the center line of the front machine wall. According to the intervertebral fusion machine, a polyetheretherketone material is used, a bone grafting window and the developing needles are designed, the millipores for bone ingrowth are added, and the developingneedles are used for displaying the implantation position of the fusion machine under the X-ray; artificial bones of which the diameters are identical to the diameters of the millipores are implantedinto the bone ingrowth millipores for inducing bone ingrowth, bone fusion on a supporting surface can be improved, the area of intervertebral fusion is effectively increased, and the stability effectof the vertebral body of intervertebral fusion after the operation is improved.

The invention relates to an absorbable ankle fusion device, which comprises a prismatic hollow pile frame made from polymer materials capable of being absorbed by the human body, and a shoulder frame matched with the pile frame and made from polymer materials capable of being absorbed by the human body; wherein the lateral surface of the pile frame is provided with a bone graft contact hole and anutrient foramen; a penetrating hole spliced with the pile frame is arranged in the middle of the shoulder frame, the two ends of the shoulder frame are respectively provided with two wings which bend downwards and are respectively arranged in gaps between a malleolus medialis and an ankle bone and between a lateral malleolus and the ankle bone, and two wings of the shoulder frame are respectively provided with bone graft contact holes and nutrient foramens. The absorbable ankle fusion device has the advantages of simple structure, convenience for operation and use safety, can realize the interior fixation between a tibia and the ankle bone and enable a grafted autologous bone to fully contact a surface of a new bone wound, which is beneficial to the formation of bone fusion.

A prosthetic implant is provided that has an implantable magnetic base structure that supports or couples with a prosthetic superstructure for implantation in a mammal. The implantable base more quickly fuses with surrounding tissue or bone with the aid of a magnetic field. The superstructure abuts and is supported by the implantable base, and each comprises a biocompatible magnetic material to establish a magnetic field in the region of the tissue surrounding the implantable base. An anchoring arrangement may be employed to fasten the superstructure to the base. Together, the magnetic base, superstructure, and / or anchoring arrangement are positioned relative to each other to concentrate a magnetic field in the region of the implant to facilitate fusion of the base structure with surrounding bone or tissue. Advantageously, the magnetic field shortens the healing time and retards bacterial growth to quickly fuse the base structure with the surrounding bone or tissue.

The invention discloses a functional part of a porous titanium interbody fusion cage and namely discloses a pore structural portion of a porous titanium interbody fusion cage. The pore structural portion is used for guiding ingrowth of new bones. The pore structural portion is exposed out of the top, bottom, front and rear of the fusion cage in opened manner, and an open growth space is provided for the effective growth of bones and the like. The pore structural portion of the porous titanium interbody fusion cage can function on its own, and may also cooperate with a support structural portion to arrive at interbody treatment.

The invention belongs to the technical field of medical prosthesis manufacturing, and relates to a lower cervical vertebra anatomical titanium cage which comprises a titanium cage body; the upper endof the titanium cage body is of a dome structure, the lower end of the titanium cage body is of an inclined structure, a net structure is arranged between the dome structure and the inclined structure, and the net structure is connected with the dome structure and the inclined structure; the net structure comprises a first front surface, a first rear surface, a first left side face and a first right side face which are connected, the first front surface and the first rear surface are each of an arc-shaped structure, and the first left side face and the first right side face are each of a planestructure. The upper end of the lower cervical vertebra anatomical titanium cage is designed to be of the dome structure according to cervical vertebra anatomical data measurement results. The lowerend of the lower cervical vertebra anatomical titanium cage is designed to be of the inclined structure, the angle of a cervical vertebra operation segment is simulated, and therefore the contact areabetween the titanium cage and a cervical vertebra end plate is enlarged, the stress concentration phenomenon is reduced, stress is evenly distributed on the surface of the end plate, and the occurrence rate of collapse of the titanium cage is reduced.

The invention provides an interbody fusion cage and a preparation method thereof. The interbody fusion cage includes a first porous structure layer, a second porous structure layer and a solid structure layer, wherein multiple pores are formed in the first porous structure layer, multiple pores are formed in the second porous structure layer, one end of the solid structure layer is connected to the first porous structure layer, and the other end of the solid structure layer is connected to the second porous structure layer; the first porous structure layer, the second porous structure layer and the solid structure layer are an integrated structure made of a polymer material, and the elasticity modulus of the solid structure layer is smaller than that of the first porous structure layer andthat of the second porous structure layer. The interbody fusion cage has a good elastic property and good integration with human skeleton series after implantation, and can slow down or avoid degeneration of intervertebral discs of adjacent segments to ensure a long-term curative effect.

The invention provides a slidable and self-locking atlantoaxial interbody fusion cage. The slidable and self-locking atlantoaxial interbody fusion cage comprises an upper sliding piece component, a lower sliding piece component and a wedge-shaped supporting block for supporting the upper sliding piece component and the lower sliding piece component, wherein the upper sliding piece component and the lower sliding piece component are connected in a sliding manner; and the wedge-shaped supporting block is arranged between the upper sliding piece component and the lower sliding piece component. According to the atlantoaxial interbody fusion cage, the defects of a traditional atlantoaxial interbody fusion cage are overcome, and an surgical approach and clinical operation are fully taken into consideration; and the fusion cage is composed of two prosthesis bodies capable of sliding relatively and the wedge-shaped supporting block is arranged, so the fusion cage can conveniently support the atlantoaxial joint, and locking can be conducted so as to ensure the stability of the atlantoaxial joint.

The invention discloses a tapping type zero-incisure cervical fusion cage which comprises a supporter part and a fixing screw. The whole supporter part is of a circular-truncated-cone-shaped structure. A tapping type thread is formed in the side face wall of the supporter part. The supporter part is provided with a bone grafting groove and the fixing screw. The tapping type zero-incisure cervicalfusion cage has a good self-stabilizing structure, the auxiliary fixing of an anterior titanium plate is avoided, the influences on cervical soft tissue are low, and the tapping type zero-incisure cervical fusion cage has the advantages of being easy to assemble, convenient to implant, capable of forming a small wound, low in postoperative complication occurrence rate and the like.

The invention provides a 3D printing tantalum rod. The tantalum rod includes a threaded part and a multi-level hole part, wherein the threaded part and the multi-level hole part are provided with a through hole penetrating up and down, and the surfaces of the threaded part and the multi-level hole part are both provided with circular holes. The tantalum rod can promote bone conduction and bone fusion, the pore structure can be adjusted, and the mechanical properties such as elastic modulus can be adjusted and are closer to the performance of human bones without stress shielding problems. The tantalum rod is provided with the through hole, so that accurate positioning during operation is facilitated; through the through hole, a related substance is conveniently taken out and injected to achieve the effect of continuous decompression; and the threaded part of the tantalum rod has a 5 degree self-locking anti-rotation thread structure, so that previous unsatisfactory bone growth due to fretting and surgical revision are avoided.