A 
system for regulating 
blood pressure by stimulating an 
afferent pathway to the brain which produces an 
efferent output in kidneys includes a 
electrode device adapted for implantation in the cervical region, a stimulator generator, a cable connecting the 
electrode device and the stimulator generator, wherein the cervical region is generally located between a pair of common 
carotid arteries, above an 
aortic arch and in front of 
cervical vertebrae C2 and C3. A method of implantation includes placing the 
electrode device in the cervical region, selectively energizing the device in accordance with a stimulation scheme, assessing any changes in the patient's 
blood pressure, selectively energizing the device in accordance with another stimulation scheme, and assessing any changes in the patient's blood, for determining an 
optical stimulation scheme, wherein stimulation scheme involves parameters including, for example, position, placement and configuration of the electrode device in relation to surrounding tissue and / or organs, selection of electrodes energized, width, frequency and amplitude of stimulation current.