The invention discloses a design method of a prosthesis so as to meet motion functions and biological functions of kneecaps, and achieve the purpose of semi-kneecap prosthesis exchange. The design method of the prosthesis comprises the steps of obtaining high-precision three-dimensional raw data of the knee joint of a patient through CT or MRI, and constructing a kneecap three dimensional model bya reverse engineering method; and according to the feature points of the kneecaps, constructing the cutting plane of the kneecap three dimensional model, and by using the cutting plane, cutting the kneecap three dimensional model to obtain a three dimensional model A1 designed according to the prosthesis and a kneecap reserving band A2; and based on A1, designing a protrusion A3 on the cutting plane, and besides, based on A2, designing a groove A4 corresponding to the A3 in the position same as the cutting plane, to obtain a semi-kneecap prosthesis fixing structure. The semi kneecap prosthesis material is polyetheretherketone. A mold adopting a material increasing manufacturing method, a conventional manufacturing method or a combination of the material increasing manufacturing method andthe conventional manufacturing method is adopted for manufacturing the personalised kneecap prosthesis. Through an injection molding method, a high strength prosthesis structure and a high surface finish kneecap prosthesis articular facet are obtained.