The invention discloses a human waist joint simulation system based on the series-parallel connection of pneumatic muscles and an air cylinder. The pneumatic muscles simulating the human muscles and the thin-walled air cylinder drive the ribs and the vertebrae to move, and the system has the function of completely simulating the movement of the human waist joints. The human waist joint simulationsystem is mainly composed of the pelvis, the ribs, the vertebra, the thin-walled air cylinder, the pneumatic muscles and the like, and the pneumatic muscles simulating the effects of the latissimus dorsi muscles, the obliquus externus abdominis muscles, the rectus abdominis muscles, the erector spinae muscles and the like and the thin-walled air cylinder drive the rib and vertebral joints to rotate around a vertical axis, a sagittal axis and a coronal axis and make linear movement in the three directions. The system is driven by the pneumatic muscles and the thin-walled air cylinder, has the advantages of compact structure, multiple degrees of freedom and good explosion-proof performance, and can be used for medical diagnosis, teaching demonstration, exhibition and the like.