4 results about "Effervescent granules" patented technology

The invention provides a complex microbial inoculant, effervescent granules and application, and belongs to the technical field of microorganisms. The invention provides a complex microbial inoculant. The complex microbial inoculant comprises bacillus halotolerant SSF1 and bacillus licheniformis LU1. The complex microbial inoculant has relatively high enzyme activity of endo-glucosidase and relatively good cellulose degradation capability. The complex microbial inoculant is used as an active component and can be combined with a disintegrating agent, a lubricating agent, an adhesive and the like to prepare effervescent granules. The obtained effervescent granules are short in disintegration time and large in foaming amount, the pH value of the effervescent granules is close to the pH value of pure water after the effervescent granules are completely disintegrated, the viable count of the complex microbial inoculant can be efficiently kept, and the complex microbial inoculant can maintain high activity. The result of the embodiment shows that when the effervescent granules of the complex microbial inoculant are applied to wheat planting, the growth of wheat can be remarkably promoted, the germination number of wheat can be increased, and the overground part length, the underground part length, the fresh weight root-crown ratio and the dry weight root-crown ratio of wheat can be improved.

The present application relates to a kind of calcium carbonate D3 effervescent granules and its preparation method, belong to biological medicine preparation technical field.The present application utilizes calcium carbonate and anhydrous citric acid to prepare granule A, utilizes vitamin D3 and alkali source to prepare basic granule B, then granule A, granule B are mixed with acid source again to obtain calcium carbonate D3 effervescent granules;The present application of calcium carbonate D3 effervescent granules meets water and causes acid-base neutralization reaction, quickly forms suspension;The present application of calcium carbonate D3 effervescent granules does not contain ethanol aqueous solution, anhydrous ethanol, isopropanol and other organic solvents, product safety is higher, production cost is lower;Calcium carbonate D3 effervescent granules accelerate 6 months, character is stable, does not occur acid-base reaction, does not produce carbon dioxide gas, stability is good, solve the effervescent granule in the process of placement, prone to acid-base reaction, produce carbon dioxide, the problem of affecting product quality.

The application discloses a preparation process of effervescent granules of a composition containing phenylephrine hydrochloride, which is prepared by taking phenylephrine hydrochloride as a main active ingredient, and by adding antiallergic agents, expectorants, antitussives, antipyretics, anti-inflammatory agents and combinations thereof. In order to prevent degradation of phenylephrine hydrochloride, the phenylephrine hydrochloride is first wrapped with PEG together with an alkali source, and then mixed with other components to prepare the effervescent granules. The effervescent granules prepared by the method have the advantages of high drug stability, rapid effect, high bioavailability, convenient carrying and low cost, and are suitable for children, the elderly and patients who cannot swallow solid preparations.

The application belongs to the technical field of veterinary medicine preparation, and particularly discloses a high-stability veterinary florfenicol effervescent granule and a preparation method thereof, and aims to solve the problem that florfenicol is prone to amide bond hydrolysis and racemization degradation in an acid-base environment of the effervescent granule in the prior art. In the application, a core-shell buffer mesocrystal with sodium phosphate dibasic as the core and citric acid as the shell is used as a drug active chemical protection core, and when water is encountered, the outer shell citric acid is instantaneously dissolved to establish a protective pH microenvironment; and a hydrophilic PEG / hydrogenated vegetable oil coated effervescent acid source is used to realize programmed disintegration. The product has outstanding accelerated stability, and the degradation product is less than 0.5% in 30 days, and the process is simple and controllable.