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122 results about "Polyvinylpolypyrrolidone" patented technology

Polyvinylpolypyrrolidone (polyvinyl polypyrrolidone, PVPP, crospovidone, crospolividone or E1202) is a highly cross-linked modification of polyvinylpyrrolidone (PVP). The cross-linked form of PVP is used as a disintegrant (see also excipients) in pharmaceutical tablets. PVPP is a highly cross-linked version of PVP, making it insoluble in water, though it still absorbs water and swells very rapidly generating a swelling force. This property makes it useful as a disintegrant in tablets.

MOF-5 and preparation and application thereof, polymer self-lubricating composite material and preparation and application thereof

ActiveCN119775584ASodium acetateFiber
The invention belongs to the technical field of functional materials, and provides MOF-5 and preparation and application thereof, and a polymer self-lubricating composite material and preparation and application thereof. The preparation method comprises the following steps: mixing zinc salt, terephthalic acid, an end-capping reagent (polyvinyl pyrrolidone or polyvinyl alcohol), a weak base (triethylamine or sodium acetate) and a solvent, and carrying out ultrasonic treatment. The end-capping reagent and the weak base are added, so that the microstructure of the MOF-5 is lamellar, and the specificity of the crystal face is exposed, and when the MOF-5 is used as a functional filler to be applied to the self-lubricating polymer, the tribological performance can be improved. The MOF-5 mainly provides a reinforcing effect similar to that of crushed carbon fibers, and in the frictional wear process of the polymer self-lubricating composite material and a metal pair, the MOF-5 mainly serves as a bearing phase to bear main loads and makes contact with the metal pair to form a uniform and continuous transfer film on the surface of the metal pair, so that the metal pair is protected against abrasion. The tribological property of the polymer self-lubricating composite material is improved.
Owner:LANZHOU INSTITUTE OF CHEMICAL PHYSICS CHINESE ACADEMY OF SCIENCES

A conductive paste of oligomeric wall tubes composite graphene for a positive electrode sheet and a preparation method thereof

The present invention provides a conductive paste of oligomeric walled nanotubes composite graphene and a preparation method thereof, comprising raw materials in the following mass ratios: 1-4% of oligomeric walled carbon nanotubes, 0.1-0.5% of graphite, 0.5-2% of a dispersion aid, 0.5-1% of a viscosity reducer, 0.1-0.5% of a conductive aid, and the balance being NMP; the dispersion aid includes a polyvinylpyrrolidone with a small molecular weight, a polyvinylpyrrolidone with a large molecular weight, and a polyaniline composite material. By adding graphene, the present invention makes use of the softer characteristics of graphene to enable the oligomeric walled carbon nanotubes to fit more closely with the cathode active material and have a wider contact area, thereby improving the conductivity of the material and the cycle performance, rate performance, etc. of the battery.
Owner:CHONGQING ZHONGRUN NEW MATERIALS CO LTD

PHOTOCATALYTIC SELF-CLEANING POLYPYRROLE / TiO2-PVDF NANOCOMPOSITE BASED FILTRATION MEMBRANE

A filtration membrane including a first layer comprising a polyester terephthalate nonwoven fabric, a second layer comprising a polyvinylidene fluoride matrix doped with a polyvinylpyrrolidone and titanium dioxide nanoparticles, and a third layer comprising a polypyrrole polymer. A method of making the membrane is also described. The membrane of the present disclosure is self-cleaning under visible light irradiation conditions.
Owner:KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS

Fnerenone tablet and preparation method thereof

The invention provides a pharmaceutical composition containing fenerenone, which comprises the following components in percentage by weight: 1.0%-30.0% of fenerenone, 1.0%-5.0% of hydroxypropyl methylcellulose, 0.1%-1.0% of lauryl sodium sulfate, 5.0%-15.0% of polyvinylpolypyrrolidone and 0.5%-5.0% of sodium stearyl fumarate. The filler is microcrystalline cellulose and lactose monohydrate, a wet granulation process is adopted, the pharmaceutical composition has the characteristics of stable and rapid dissolution and rapid disintegration of the fenerenone, the process is simple, the production steps are simplified, the production efficiency is improved, and the cost is reduced.
Owner:JIANGSU WANBANG BIOPHARMLS

Preparation method of polyvinylpyrrolidone-high dielectric constant composite film and high dielectric constant photovoltaic packaging adhesive film

The invention discloses a preparation method of a polyvinylpyrrolidone-high dielectric constant composite film and a high dielectric constant photovoltaic packaging adhesive film. The preparation process of the polyvinylpyrrolidone-high dielectric constant composite film comprises the following steps: carrying out surface hydroxylation treatment on a high dielectric constant substance raw material to obtain a high dielectric constant substance a of which the surface is coated with hydroxyl; carrying out surface modification treatment on the high-dielectric-constant substance a: adding a vinyl silane coupling agent, introducing double bonds on the surface of the high-dielectric-constant substance a, adding a vinyl pyrrolidone monomer, and carrying out polymerization, so that the surface of the high-dielectric-constant substance a is coated with a polyvinyl pyrrolidone polymer to obtain an active high-dielectric-constant substance b; and mixing the high dielectric constant substance b and EVA, dissolving in a DMF / dichloromethane solvent, magnetically stirring to obtain a uniform solution, and then preparing the membrane through an electrostatic spinning process. According to the high-dielectric photovoltaic packaging adhesive film, the polyvinylpyrrolidone-high-dielectric-constant composite film is attached between two layers of EVA adhesive films through hot pressing, and the high-dielectric-constant EVA adhesive film of a three-layer structure is obtained.
Owner:NANCHANG UNIV

Synthesis procedure of homopolymers and copolymers based on vinyl ionic liquids, n-vinylpyrrolidone or vinylpyridine and the methodology for their application as catalysts in alkylation reactions of isoparaffins and olefins

The present disclosure relates to a procedure for the synthesis of polymers (homo and copolymers) of the poly (ionic liquid) (PIL) type. The homopolymers are derived from polyvinylimidazolium, polyvinylpyrrolidone or polyvinylpyridine and the copolymers from monomers of vinyl ionic liquids (ILs) are derived from imidazole and N-vinylpyrrolidone. The structural modification of these homopolymers and copolymers occurs by using strong inorganic acids such as sulfuric, chlorosulfonic and bromosulfonic, among others, and halide metallic salts such as AlCl3, FeCl3, CuCl, ZnCl2, and SnCl2. Also, these PILs are employed as catalysts in alkylation reactions between isoparaffins and olefins for producing alkylate gasoline.
Owner:INST MEXICANO DEL GASOLINEEO

NiCo-MOF / MXene-CNF aerogel composite material as well as preparation method and application thereof

The invention provides a preparation method of a NiCo-MOF / MXene-CNF aerogel composite material. The preparation method comprises the following steps: S1, adopting LiF and hydrochloric acid to etch MAX phase powder to prepare an MXene dispersion liquid; s2, mixing and freezing the MXene dispersion liquid and nano cellulose into ice, and drying to obtain MXene-CNF aerogel; s3, N, N-dimethylformamide, deionized water, alcohol, NiCl2. 6H2O, CoCl2. 6H2O, trimesic acid and polyvinyl pyrrolidone are mixed, and a mixed solution is obtained; s4, after the mixed solution is subjected to ultrasonic dispersion, the MXene-CNF aerogel is added, the mixture is placed in a drying oven at the temperature of 120 DEG C to 200 DEG C to react for 6 h to 14 h, and the NiCo-MOF / MXene-CNF aerogel composite material is obtained. NiCo-MOF with a two-dimensional nanosheet structure is grown on the surface of MXene-CNF aerogel with a three-dimensional structure in situ to form the NiCo-MOF / MXene-CNF aerogel composite material with a three-dimensional porous network structure, and the composite material effectively avoids irreversible agglomeration and self-stacking phenomena of an MXene material and provides an efficient channel for migration of electrolyte ions; compared with the pure MXene-CNF aerogel, the NiCo-MOF / MXene-CNF aerogel composite material has more excellent mass specific capacitance and charge storage capability.
Owner:ANYANG INST OF TECH

Water-based paint for surfaces of multiple materials as well as preparation method and application of water-based paint

The invention relates to the technical field of water-based paint, in particular to water-based paint for surfaces of multiple materials and a preparation method of the water-based paint for the surfaces of the multiple materials. 4-10 parts of a coalescing agent; 0.2 to 0.5 part of a defoaming agent; 0.3 to 0.8 part of a leveling agent; 3-5 parts of a wax emulsion; 0.2 to 0.5 part of a wetting agent; 0.5 to 2 parts of a thickening agent; 2 to 4 parts of polyvinyl butyral; 1-3 parts of polyethylene glycol monomethyl ether; 0.5 to 2 parts of polyvinyl pyrrolidone; the pure acrylic emulsion is selected as a main film forming substance, carboxyl, hydroxyl and other functional groups on a molecular chain of the pure acrylic emulsion can provide abundant reaction sites, polyvinyl butyral is introduced, an aldehyde group in a molecular structure of the polyvinyl butyral can form a hydrogen bond with the surface of a base material, and meanwhile, an interpenetrating network is formed with the main emulsion through a unique chain segment structure of the polyvinyl butyral; through introduction of polyethylene glycol monomethyl ether, a flexible chain segment improves the leveling property of the system.
Owner:ZHEJIANG XINGHUI NEW MATERIALS CO LTD

Process for obtaining ore dust suppressant resin, ores dust suppressant resin, process for inhibition of ore particulate emission and resin use

The proposed invention is a process for obtaining the ore dust suppressant resin with the chemical recycling of Poly thermoplastic polymer (Ethylene Terephthalate) or PET. It is proposed a method for obtaining the resin by using the depolymerization reaction methodology of the Poly polymer (Ethylene Terephthalate) obtained from post-consumption PET bottles, in the presence of cationic surfactant hexadeciltrimetrilamonio bromide (CTAB). The resin is thus obtained being subsequently added to the same PVP K-90 (Polyvinylpyrrolidone) as increasing load on the final viscosity of the resin. Other additives such as lignin extracted from plants such as leaves and tree branches may also be added, in this case, incorporated to make the resin more hydrophobic.
Owner:VALE SA +1

Smanh-blended membranes for immobilizing functional molecules

PCT designated stage expiredWO2025021583A1MembranesSemi-permeable membranesPolymer sciencePyrrolidinones
The present disclosure relates to polysulfone, polyether-sulfone or polyarylethersulfone based membranes for use in extracorporeal blood treatment applications comprising a blend of (i) a polysulfone (PS), a polyethersulfone (PES) or a polyarylethersulfone (PAES); (ii) a polyvinylpyrrolidone (PVP); and (iii) a poly(styrene-alt-maleic anhydride)- copolymer which are configured for the immobilization of amine-bearing functional molecules on the surface of the membrane. The disclosure further relates to a method for producing the membranes and a filtration and / or diffusion device comprising the membrane.
Owner:GAMBRO LUNDIA AB +3

Antibacterial tissue patch with excellent adhesion as well as preparation method and application of antibacterial tissue patch

The invention relates to an antibacterial tissue patch with excellent adhesion as well as a preparation method and application of the antibacterial tissue patch. The antibacterial tissue patch is formed by alternately coating at least one carrier layer and at least one antibacterial tissue adhesion layer, the carrier layer is a film-forming polymer, the antibacterial tissue adhesion layer is an antibacterial copolymer, and the antibacterial copolymer is poly (N-vinyl pyrrolidone-acrylic acid-dopamine acrylate-dopamine quinone acrylate). The preparation method comprises the following steps: dissolving the film-forming polymer in an organic solvent, coating, and drying to obtain the carrier layer; then preparing an antibacterial tissue adhesion layer, and then coating the tissue adhesion layer with the carrier layer to form a multi-layer alternating structure which is excellent in antibacterial property, high in biocompatibility and suitable for functional composite materials.
Owner:NEO MODULUS (SUZHOU) LIFE SCI & TECH CO LTD +1

Precursor fibers for lignin-based carbon fibers, preparation and use thereof

A precursor fiber of a lignin-based carbon fiber is described, said precursor fiber having a content of a water-soluble lignin salt (A). A particular feature of these precursor fibers is that a water-soluble polyvinyl pyrrolidone or polyvinyl pyrrolidone derivative (B) is included therein. Advantageous methods for the preparation of these precursor fibers and their advantageous use for the preparation of carbon fibers by carbonization and optionally subsequent graphitization are also described.
Owner:HARDWOOD TECH LTD

Benazepril hydrochloride and hydrochlorothiazide tablet and preparation method thereof

The invention provides benazepril hydrochloride and hydrochlorothiazide tablets and a preparation method thereof, and relates to the technical field of pharmaceutical preparations. The benazepril hydrochloride and hydrochlorothiazide tablet is prepared from the following raw material components: benazepril hydrochloride, hydrochlorothiazide, lactose, hydroxypropyl methylcellulose, polyvinylpolypyrrolidone, hydrogenated castor oil and opadry coating powder. The weight content of the lactose in the benazepril hydrochloride and hydrochlorothiazide tablet is 50 wt%-82 wt%. In the coating process of preparing the tablets, the drying temperature is 30-60 DEG C. The prepared benazepril hydrochloride and hydrochlorothiazide tablet compound preparation is high in stability, high in release rate and low in impurity content. According to the benazepril hydrochloride hydrochlorothiazide tablet, the stability of the product is improved, and the problem that the impurity content of the benazepril hydrochloride hydrochlorothiazide tablet is easy to greatly increase during long-term storage is solved.
Owner:GUANG DONG WAN TAI KE CHUANG YAO YE YOU XIAN GONG SI

Inhibitor containing sodium propionate hydrate for guaranteeing flow of carbon dioxide conveying pipeline

The invention relates to a sodium propionate-containing hydrate inhibitor for guaranteeing flow of a carbon dioxide conveying pipeline, which comprises sodium propionate, glycine, polyvinyl pyrrolidone and methanol, and the sodium propionate, the glycine, the polyvinyl pyrrolidone and the methanol are mixed with a sodium chloride solution serving as a solvent, so that the sodium propionate, the glycine, the polyvinyl pyrrolidone and the methanol are mixed according to the molar percentage as follows: 1-15 mol% of the sodium propionate, 1-15 mol% of the glycine, 0.1-1 mol% of the polyvinyl pyrrolidone and 5-60 mol% of the methanol. The sodium propionate, the glycine, the polyvinyl pyrrolidone and the methanol are compounded for use, so that the effect of a single inhibitor is enhanced, the application range is wider, a better inhibition effect is achieved at a lower concentration, and the generation of carbon dioxide hydrate can be better inhibited. The mixed use reduces the cost of the inhibitor, reduces the use amount of the mixture, and weakens the toxicity and pollution of the inhibitor.
Owner:XINJIANG DUNHUA PETROLEUM TECH CO LTD +1

Expanded polytetrafluoroethylene artificial blood vessel and manufacturing method thereof

The invention relates to a preparation method of an artificial blood vessel, the artificial blood vessel is composed of a porous support layer, a biodegradation layer and an antithrombotic layer, and the method comprises the following steps: soaking an expanded polytetrafluoroethylene substrate with silver nitrate doped polyvinyl pyrrolidone-poly-N-isopropylacrylamide to obtain the porous support layer; and then assembling a biodegradable material and an antithrombotic material as a biodegradable layer and an antithrombotic layer. The invention also relates to the artificial blood vessel prepared by the method.
Owner:NANJING FIBERGLASS RES & DESIGN INST CO LTD

Oil-resistant anti-freezing corrosion-inhibition foaming agent for gas well as well as preparation method and application thereof

The invention belongs to the technical field of natural gas extraction, and particularly relates to an oil-resistant anti-freezing corrosion-inhibition foaming agent for a gas well as well as a preparation method and application of the oil-resistant anti-freezing corrosion-inhibition foaming agent. The oil-resistant anti-freezing corrosion inhibition type foaming agent for the gas well is prepared from the following components in parts by mass: 40 to 70 parts of sodium alpha-olefin sulfonate, 10 to 20 parts of cocamidopropyl dimethylamine oxide, 1 to 10 parts of modified nanoparticles, 20 to 40 parts of betaine zwitterionic surfactant, 5 to 15 parts of corrosion inhibitor, 1 to 15 parts of polyvinyl pyrrolidone and the balance of water. After the foaming agent is aged at the low temperature of-30 DEG C, the liquid carrying rate of the foaming agent can be up to 83.8% in the range that the condensate oil content is 10%-50%, the degree of mineralization resistance is up to 2 * 10 mg / L, and the corrosion inhibition rate in a composite sample solution containing 20 wt% of condensate oil, 20 wt% of methanol and saturated CO2 can be up to 75% or above; the requirements of extreme composite working conditions of high salinity, gas condensate pollution and acid gas corrosion in the middle and later periods of gas well development can be met, and the dual effects of drainage gas recovery and underground protection are achieved.
Owner:PANJIN LIAOYOU FENGHUA PETROLEUM MACHINERY MANUFACTURING CO LTD

A medical adhesive tape and its preparation method

This invention relates to the field of medical tape technology and discloses a medical tape and its preparation method, comprising the following steps: mixing polyvinylpyrrolidone, polyvinyl alcohol, antibacterial filler, glycerin and deionized water, stirring to obtain an antibacterial adhesive; coating the antibacterial adhesive onto the surface of a nonwoven fabric, drying to obtain an adhesive layer; and bonding a fabric substrate to the adhesive layer to obtain the medical tape. The antibacterial filler contains a composite antibacterial material with a multilayered antibacterial structure, exhibiting excellent antibacterial activity. Furthermore, the composite black phosphorus nanosheets are adhered between the layers, forming a composite layered material with high oxygen barrier properties, preventing black phosphorus from easily oxidizing upon contact with oxygen in the air, thus avoiding the loss of antibacterial activity of the medical tape. The formed composite layered material also possesses good mechanical properties, can weaken the stress in the tensile test of the medical tape, thereby distributing pressure, and has good flexibility.
Owner:CHANGZHOU MAJOR MEDICAL PROD CO LTD

Rain night type road marking paint

The application discloses a rain night type road marking paint. The road marking paint is prepared from the following raw material components in parts by weight: modified acrylic emulsion 50-80 parts, polyvinylpyrrolidone 30-50 parts, curing agent 8-15 parts, wear-resistant agent 5-8 parts, glass microbead 30-50 parts, potassium feldspar powder 10-20 parts, antioxidant 3-5 parts, dispersing agent 3-6 parts, anti-sedimentation agent 3-5 parts, drying catalyst 1-3 parts, and toughening agent 2-5 parts. The road marking paint prepared by the application has good reflection performance in rain night and daytime; the combination use of the glass microbead and the potassium feldspar powder improves the retroreflective coefficient of the material; the combination use of the adipic dihydrazide and 3,3',4,4'-benzophenonetetracarboxylic dianhydride reduces the drying time; and the combination use of (3,3,3-trifluoropropyl)trimethoxysilane and potassium hexatitanate whisker improves the wear resistance of the material.
Owner:HEBEI JINBERUI TRANSPORTATION TECH CO LTD

Edoxaban tosylate orally disintegrating tablet and preparation method thereof

The invention belongs to the technical field of pharmaceutical preparations, and particularly relates to an esdoxaban tosylate orally disintegrating tablet and a preparation method thereof. The ludoxaban tosylate orally disintegrating tablet is prepared from particles and external auxiliary materials, the particles comprise the following components: indedoxaban tosylate, a filler, a disintegrating agent 1, an adhesive and a solubilizer, the disintegrating agent 1 is a mixture of polyvinylpolypyrrolidone and croscarmellose sodium, and the adhesive is hydroxypropyl methylcellulose; the external auxiliary materials comprise the following components: a disintegrating agent 2, a flavoring agent, a coloring agent and a lubricating agent, wherein the disintegrating agent 2 is polyvinylpolypyrrolidone. The adhesive, the disintegrating agent and the asparaginic acid which are specifically combined are adopted to synergistically realize a rapid drug release effect, blank rapid granules do not need to be prepared, the preparation process is simpler, and meanwhile, the composition has the characteristic of good taste.
Owner:GUANG DONG WAN TAI KE CHUANG YAO YE YOU XIAN GONG SI

Composite hollow fiber membrane and preparation method thereof

The invention discloses a composite hollow fiber membrane and a preparation method thereof, and belongs to the technical field of composite membranes, the method comprises the following steps: a first mixed solution and a second mixed solution are respectively obtained, the first mixed solution comprises dimethylacetamide and ethyl silicate, the second mixed solution comprises dimethylacetamide and polyvinylidene fluoride (PVDF), and the first mixed solution and the second mixed solution are mixed; the first mixed solution or the second mixed solution also contains polyvinyl pyrrolidone (PVP); mixing the first mixed solution and the second mixed solution to obtain a membrane casting solution; and defoaming the membrane casting solution to prepare the composite hollow fiber membrane. Through interaction of in-situ formed silicon oxide and special functional groups of PVP, additional constraint is applied to molecular chain movement of PVP, meanwhile, constraint is applied to molecular movement of PVDF macromolecular chains, and the water filtration performance of the membrane can be changed; the inorganic particles can be stably dispersed in the membrane, have high hydrophilicity, are negatively charged in a normal water environment, and can provide hydrophilic and electrical effects in fluid separation to achieve the effect of improving separation.
Owner:NINGBO JIANRONG SPECIAL SEPARATION MEMBRANE TECHNOLOGY CO LTD

Preparation method for prolonging validity period of erythromycin ethylsuccinate orally disintegrating tablet

The invention discloses a preparation method for prolonging the validity period of erythromycin ethylsuccinate orally disintegrating tablets. The preparation method comprises the following steps: sequentially putting low-substituted hydroxypropyl cellulose, microcrystalline cellulose, aspartame, carboxymethyl starch sodium and polyvinylpolypyrrolidone into a wet granulation mixer, covering with a cover, starting equipment, carrying out low-speed dry mixing for 3 minutes, slowly adding low-concentration hydroxypropyl methylcellulose slurry from a feed port of a pot cover, and carrying out low-speed wet mixing for 3 minutes; stopping the machine, opening the cover, scraping powder on the inner surface of the pot cover and the periphery of the inner side of the pot by using a clean scraper, adding erythromycin ethylsuccinate raw materials, covering the cover, starting equipment, carrying out low-speed wet mixing for 3 minutes, and carrying out high-speed wet mixing for 2 minutes. By improving the medicine production process, the stability and durability of the medicine are improved, so that the validity period of the medicine is prolonged, and meanwhile, the effectiveness and safety of the medicine can still be kept within the prolonged validity period.
Owner:HUIHAI PHARM (HUBEI) CO LTD

A palladium-zinc-bismuth oxide catalyst and a preparation method and application thereof in oxidation of beta-hydroxy ester

The application provides a palladium-zinc-bismuth oxide catalyst and a preparation method and application thereof in beta-hydroxy ester oxidation, and the preparation steps of the catalyst comprise the following steps: dissolving a bismuth salt and an alkali into water, adding carbon powder to be ultrasonically dispersed, then heating to reflux to perform reaction, and then performing filtration and drying to obtain Bi2O3 / C; dissolving a palladium salt, a zinc salt, L-ascorbic acid and polyvinyl pyrrolidone into water, adding Bi2O3 / C to be ultrasonically dispersed, then heating to reflux to perform reaction, and then performing filtration, drying and calcination to obtain the palladium-zinc-bismuth oxide catalyst. The obtained catalyst can be used in beta-hydroxy ester oxidation reaction, and beta-keto ester products can be obtained with high yield and high selectivity. The catalyst has novel structure, simple preparation process, can efficiently catalyze beta-hydroxy ester oxidation to obtain beta-keto ester products, has the advantages of fast reaction speed, high raw material conversion rate and high product selectivity, and has important application prospect.
Owner:WANHUA CHEM GRP CO LTD

Low-moisture high-heat-resistance solution type acrylic acid adhesive and preparation method thereof

The invention relates to the technical field of lithium battery diaphragms, in particular to a low-moisture and high-heat-resistance solution type acrylic acid binder and a preparation method thereof. Through the synergistic effect of the protective colloid composite cross-linking monomer, the low moisture content is achieved in a breakthrough mode. Wherein the steric hindrance effect of the polyvinyl alcohol in the protective colloid mixture inhibits exposure of hydrophilic groups, the polyvinyl pyrrolidone improves the dispersion stability, and the polyether polyol enhances the film-forming flexibility; hydroxyethyl acrylamide and diacetone methacrylamide in the crosslinking monomer mixture construct a dual crosslinking network, so that the covalent bond density between molecular chains is remarkably enhanced, and cyano groups of acrylonitrile further reduce the moisture adsorption path and improve the interface anchoring force through strong polarity and hydrophobicity; the three components cooperate with each other to achieve a heat-resistant effect which can only be achieved by a high addition amount in the prior art under a low addition amount, and meanwhile, the problem of diaphragm deformation caused by high-temperature long-time reaction is avoided.
Owner:GUANGZHOU RONGDONG NEW MATERIAL CO LTD

Purpureocillium lilacinum for preventing and treating root rot and soil nematode diseases of food crops, microbial agent and application of Purpureocillium lilacinum and microbial agent

The invention provides purpureocillium lilacinum for preventing and treating root rot and soil nematode diseases of food crops, a microbial inoculum and application of the purpureocillium lilacinum and the microbial inoculum. The name of the Purpureocillium lilacinus is Purpureocillium lilacinus HN-17, the Purpureocillium lilacinus HN-17 is classified and named as Purpureocillium lilacinus, the Purpureocillium lilacinus HN-17 is preserved in the China General Microbiological Culture Collection Center (CGMCC), and the preservation number is CGMCC No.41954. The Purpureocillium lilacinus HN-17 can be used for preparing the Purpureocillium lilacinus. Research results show that the antibacterial effect of the purpureocillium lilacinum HN-17 on 9 kinds of plant pathogenic bacteria such as fusarium oxysporum reaches 60.42%-83.33%; the indoor nematode killing effect on wheat cyst nematode and tomato root-knot nematode reaches 100%; the optimized binder, the optimized wetting agent, the optimized stabilizer and the optimized disintegrating agent are polyvinyl pyrrolidone, lauryl sodium sulfate, CaCO3 and AlCl3 respectively; the field control effects of wheat root rot and soybean root rot are 61.08% and 80.95% respectively after seed dressing and broadcasting, the field cyst decline rates of wheat cyst nematode and soybean cyst nematode are 54.61% and 66.67% respectively, and the application value is high.
Owner:INST OF PLANT PROTECTION NINGXIA ACAD OF AGRI & FORESTRY SCI KEY LAB OF NINGXIA PLANT DISEASE & INSECT PESTS CONTROL

Microneedle-array patches with glucose-responsive matrix for closed-loop insulin delivery

Disclosed are compositions and methods for microneedle patches comprising copolymer designed for glucose triggered insulin delivery. In one aspect, disclosed herein are microneedle patches comprising insulin loaded copolymers; wherein the insulin dissociates from the microneedle in an hyperglycemic environment; wherein the copolymer comprises poly(N-vinylpyrrolidone-co-2-N(dimethylamino)ethyl acrylate-co-3-(acrylamido)phenylboronic acid and methods of their use.
Owner:NORTH CAROLINA STATE UNIV

Solid dispersion of compound and use thereof

Disclosed is a solid dispersion of a rifamycin-quinazolinone conjugated molecule, which comprises a rifamycin-quinazolinone conjugated molecule shown in formula (I) and a polymer carrier. The polymer carrier comprises one or a combination of more of hydroxypropyl methylcellulose acetate succinate (HPMCAS), hydroxypropyl methylcellulose phthalate (HPMCP), hydroxypropyl cellulose (HPC), polypropylene resin, and polyvinyl pyrrolidone (PVP). FIG. 1: AA%%%Formula (I)
Owner:TENNOR THERAPEUTICS (SUZHOU) LTD

Hydrophilic lubricating coating and preparation process

The invention relates to the technical field of medical instrument coatings, and particularly provides a hydrophilic lubricating coating and a preparation process thereof, the hydrophilic lubricating coating comprises the following components by weight: 3%-10% of polyvinyl pyrrolidone, 5%-15% of composite bonding resin, 1%-5% of a cross-linking agent, 1%-5% of an initiator, 0.1%-1% of a leveling agent, 0.1%-0.5% of an antifoaming agent, 0.2%-2% of a nanometer reinforcing filler, and 60%-80% of a mixed solution; the preparation process comprises the following steps: preparing a presol, preparing a coating liquid, coating the coating liquid, carrying out thermocuring and carrying out UV photocuring. According to the invention, through collaborative design of the composite bonding resin and a gradient cross-linking system, strong adhesive force and lasting lubricity of the coating on a PVC substrate are realized; the mechanical strength and sterilization resistance of the coating are remarkably improved by introducing the nano reinforcing filler and the PVP with controllable molecular weight; according to the scheme, a dual-curing process is creatively used, and the forming quality of the hydrophilic lubricating coating is improved.
Owner:JIESHUN MEDICAL TECHNOLOGY (WUXI) CO LTD

Super-lubricating gel with antibacterial function and preparation method thereof

The invention relates to super-lubricating gel with an antibacterial function and a preparation method of the super-lubricating gel. The super-lubricating gel is prepared from the following raw material components: QA-GelMA, a vinyl pyrrolidone monomer, N, N '-methylene bisacrylamide and ammonium persulfate, water-soluble super-lubricating molecular polyvinyl pyrrolidone is covalently grafted to gelatin macromolecular chains with carbon-carbon double bonds, and meanwhile, the polyvinyl pyrrolidone macromolecular chains are connected into a network structure through N, N '-methylene bisacrylamide molecules, so that the water-soluble super-lubricating molecular polyvinyl pyrrolidone is prevented from being dissolved and lost in a water body; the purposes of long-term lubrication and resistance reduction are achieved; besides, an epoxy group in 2, 3-epoxypropyl-trimethyl ammonium chloride molecules reacts with gelatin molecules to generate gelatin quaternary ammonium salt, and the quaternary ammonium salt has a good growth inhibition effect on microorganisms such as escherichia coli and staphylococcus aureus, so that long-term super lubrication and resistance reduction are synergistically realized.
Owner:CSIC NO 12 RES INST

Medical adhesive tape and preparation method thereof

The invention relates to the technical field of medical adhesive tapes, and discloses a medical adhesive tape and a preparation method thereof.The preparation method comprises the following preparation steps that polyvinyl pyrrolidone, polyvinyl alcohol, antibacterial filler, glycerin and deionized water are mixed and stirred, and an antibacterial adhesive is obtained; coating the antibacterial adhesive on the surface of a non-woven fabric material, drying to obtain an adhesive layer, and adhering a fabric base material to the surface of the adhesive layer to obtain the medical adhesive tape. The composite antibacterial material in the antibacterial filler contains an antibacterial multilayer structure and shows excellent antibacterial activity, and the composite black phosphorus nanosheet is adhered between layers, so that the formed composite layered material has relatively high barrier property to oxygen, and the situation that black phosphorus is in contact with oxygen in the air and is easy to oxidize, resulting in failure of the antibacterial activity of the medical adhesive tape, is avoided, and the service life of the medical adhesive tape is prolonged. The formed composite layered material has good mechanical properties, can weaken the stress of the medical adhesive tape in a tensile test so as to disperse the pressure, and has good flexibility.
Owner:CHANGZHOU MAJOR MEDICAL PROD CO LTD