28 results about "Polyvinylpolypyrrolidone" patented technology

The invention relates to a sodium propionate-containing hydrate inhibitor for guaranteeing flow of a carbon dioxide conveying pipeline, which comprises sodium propionate, glycine, polyvinyl pyrrolidone and methanol, and the sodium propionate, the glycine, the polyvinyl pyrrolidone and the methanol are mixed with a sodium chloride solution serving as a solvent, so that the sodium propionate, the glycine, the polyvinyl pyrrolidone and the methanol are mixed according to the molar percentage as follows: 1-15 mol% of the sodium propionate, 1-15 mol% of the glycine, 0.1-1 mol% of the polyvinyl pyrrolidone and 5-60 mol% of the methanol. The sodium propionate, the glycine, the polyvinyl pyrrolidone and the methanol are compounded for use, so that the effect of a single inhibitor is enhanced, the application range is wider, a better inhibition effect is achieved at a lower concentration, and the generation of carbon dioxide hydrate can be better inhibited. The mixed use reduces the cost of the inhibitor, reduces the use amount of the mixture, and weakens the toxicity and pollution of the inhibitor.

The invention relates to a preparation method of an artificial blood vessel, the artificial blood vessel is composed of a porous support layer, a biodegradation layer and an antithrombotic layer, and the method comprises the following steps: soaking an expanded polytetrafluoroethylene substrate with silver nitrate doped polyvinyl pyrrolidone-poly-N-isopropylacrylamide to obtain the porous support layer; and then assembling a biodegradable material and an antithrombotic material as a biodegradable layer and an antithrombotic layer. The invention also relates to the artificial blood vessel prepared by the method.

The invention belongs to the technical field of natural gas extraction, and particularly relates to an oil-resistant anti-freezing corrosion-inhibition foaming agent for a gas well as well as a preparation method and application of the oil-resistant anti-freezing corrosion-inhibition foaming agent. The oil-resistant anti-freezing corrosion inhibition type foaming agent for the gas well is prepared from the following components in parts by mass: 40 to 70 parts of sodium alpha-olefin sulfonate, 10 to 20 parts of cocamidopropyl dimethylamine oxide, 1 to 10 parts of modified nanoparticles, 20 to 40 parts of betaine zwitterionic surfactant, 5 to 15 parts of corrosion inhibitor, 1 to 15 parts of polyvinyl pyrrolidone and the balance of water. After the foaming agent is aged at the low temperature of-30 DEG C, the liquid carrying rate of the foaming agent can be up to 83.8% in the range that the condensate oil content is 10%-50%, the degree of mineralization resistance is up to 2 * 10 mg / L, and the corrosion inhibition rate in a composite sample solution containing 20 wt% of condensate oil, 20 wt% of methanol and saturated CO2 can be up to 75% or above; the requirements of extreme composite working conditions of high salinity, gas condensate pollution and acid gas corrosion in the middle and later periods of gas well development can be met, and the dual effects of drainage gas recovery and underground protection are achieved.

The invention discloses a preparation method for prolonging the validity period of erythromycin ethylsuccinate orally disintegrating tablets. The preparation method comprises the following steps: sequentially putting low-substituted hydroxypropyl cellulose, microcrystalline cellulose, aspartame, carboxymethyl starch sodium and polyvinylpolypyrrolidone into a wet granulation mixer, covering with a cover, starting equipment, carrying out low-speed dry mixing for 3 minutes, slowly adding low-concentration hydroxypropyl methylcellulose slurry from a feed port of a pot cover, and carrying out low-speed wet mixing for 3 minutes; stopping the machine, opening the cover, scraping powder on the inner surface of the pot cover and the periphery of the inner side of the pot by using a clean scraper, adding erythromycin ethylsuccinate raw materials, covering the cover, starting equipment, carrying out low-speed wet mixing for 3 minutes, and carrying out high-speed wet mixing for 2 minutes. By improving the medicine production process, the stability and durability of the medicine are improved, so that the validity period of the medicine is prolonged, and meanwhile, the effectiveness and safety of the medicine can still be kept within the prolonged validity period.

The invention relates to the technical field of medical instrument coatings, and particularly provides a hydrophilic lubricating coating and a preparation process thereof, the hydrophilic lubricating coating comprises the following components by weight: 3%-10% of polyvinyl pyrrolidone, 5%-15% of composite bonding resin, 1%-5% of a cross-linking agent, 1%-5% of an initiator, 0.1%-1% of a leveling agent, 0.1%-0.5% of an antifoaming agent, 0.2%-2% of a nanometer reinforcing filler, and 60%-80% of a mixed solution; the preparation process comprises the following steps: preparing a presol, preparing a coating liquid, coating the coating liquid, carrying out thermocuring and carrying out UV photocuring. According to the invention, through collaborative design of the composite bonding resin and a gradient cross-linking system, strong adhesive force and lasting lubricity of the coating on a PVC substrate are realized; the mechanical strength and sterilization resistance of the coating are remarkably improved by introducing the nano reinforcing filler and the PVP with controllable molecular weight; according to the scheme, a dual-curing process is creatively used, and the forming quality of the hydrophilic lubricating coating is improved.

The invention discloses a preparation method of hypercrosslinked macroporous adsorption resin for removing cytokines in blood purification. Macroporous styrene-divinylbenzene resin with low crosslinking degree is prepared from styrene and divinylbenzene, then secondary crosslinking is performed on the macroporous styrene-divinylbenzene resin with the low crosslinking degree by utilizing a Friedel-Grafts method to prepare the hypercrosslinked adsorption resin, residual chloromethyl reacts with enamine to generate dangling double bonds, and then the hypercrosslinked adsorption resin is prepared. And then, polyvinyl pyrrolidone and poly (hydroxyethyl methacrylate) are grafted. The hypercrosslinked adsorption resin prepared by the invention has a huge specific surface area and abundant pore channels, and has superstrong adsorption performance on cell factors represented by TNF-alpha and IL-6, and in addition, polyvinyl pyrrolidone and poly (hydroxyethyl methacrylate) are grafted on the surface of the resin, so that the blood compatibility is improved.

The application relates to a sodium propionate hydrate inhibitor containing sodium propionate for carbon dioxide conveying pipeline flow guarantee, which comprises sodium propionate, glycine, polyvinyl pyrrolidone and methanol, and the molar percentage of the four after being mixed with a sodium chloride solution as a solvent is as follows: 1-15mol% of sodium propionate, 1-15mol% of glycine, 0.1-1mol% of polyvinyl pyrrolidone and 5-60mol% of methanol. In the application, the composite use of sodium propionate, glycine, polyvinyl pyrrolidone and methanol enhances the effect of a single inhibitor, the use range is more extensive, better inhibiting effect can be achieved at a lower concentration, and the generation of carbon dioxide hydrate can be better inhibited. The mixed use reduces the cost of the inhibitor, reduces the use amount of the mixture and weakens the toxicity and pollution of the inhibitor.

The present disclosure provides coated optical articles that exhibit anti-fog properties. The coated article comprises: (1) an optical substrate; and (2) a coating applied as a topmost layer over the surface of the substrate. The coating is formed from a treatment composition comprising: (A) a polymer comprising a carboxylic acid group, a pyrrolidone group, and an alkoxysilane group; (B) an alkoxysilane containing an amino functional group, an ammonium functional group, an epoxy functional group, or an ethylenically unsaturated group; and (C) polyvinyl pyrrolidone.

The present invention relates to solid oral care compositions, such as tablets, comprising a binder system. In certain aspects, the present invention relates to solid oral care compositions comprising a binder system, wherein the binder system comprises polyvinylpyrrolidone and hydroxyethylcellulose, as well as tablets, to the use of these compositions and to methods of manufacturing these compositions.

The invention provides a melogabalin besylate sustained release preparation. The melogabalin besylate sustained release preparation is prepared from the following components: melogabalin besylate, polyoxyethylene, polyvinylpolypyrrolidone, sodium alginate and microcrystalline cellulose, the mass ratio of the melogabalin besylate to the polyoxyethylene to the polyvinylpolypyrrolidone to the sodium alginate to the microcrystalline cellulose is (0.5-8): (20-40): (5-15): (20-40): (6-35). The sustained release preparation can ensure that melogabalin besylate is continuously released and absorbed in vivo, so that the drug effect is improved, the adverse reaction is reduced and the treatment effect is enhanced while the administration frequency is reduced.

The invention provides PRP gel poor in leucocyte and low in pro-inflammatory risk as well as a preparation method and application of the PRP gel, and belongs to the field of PRP gel. The method comprises the following steps: S1, under a high vacuum condition, mixing acrylate resin, a surface modified nano silicon dioxide composite material, polyether modified polysiloxane and polyvinyl pyrrolidone to obtain PRP separation gel; s2, collecting peripheral blood by using a vacuum blood collection tube with a built-in PRP (platelet rich plasma) separation gel, and centrifuging to obtain platelet rich plasma on an interface of the PRP separation gel; s3, mixing and activating the platelet-rich plasma and an initiator to obtain the PRP gel. The precise density gradient is constructed by customizing the thixotropic separation gel, efficient layered isolation of platelets, pro-inflammatory leukocytes and erythrocytes is achieved, the high-concentration platelets are accurately enriched, meanwhile, the leukocyte content is greatly reduced, and therefore PRP products with controllable components and stable effects are achieved, and the repairing requirements of sensitive environments such as uterine cavities are met.

The invention discloses a broad-spectrum antibacterial drug which comprises a tablet core and a coating film, the tablet core comprises 500-1000 parts of levofloxacin, 50-100 parts of a diluent, 30-100 parts of a disintegrating agent, 5-30 parts of an adhesive and 10-54 parts of a lubricant, and the coating film is a gastric-soluble film coating; wherein the disintegrating agent is a compound of carboxymethyl cellulose, polyvinylpolypyrrolidone and croscarmellose sodium; the broad-spectrum antibacterial drug tablet obtained in the invention has good dissolution rate and stability, and can be rapidly disintegrated.

The disclosure provides tablets for a mouthrinse containing fluoride, an effervescent agent comprising an acid and a base, a water soluble lubricant, a binder, and a sensory modifying agent. The tablets are free of preservatives and free et alcohol. In certain embodiments, the effervescent agent contains citric acid and sodium bicarbonate. The water soluble lubricant may include polyethylene glycol (PEG), potassium sorbate, sodium benzoate, calcium sorbate, PEG with one or more of trisodium citrate, calcium ascorbate, and mixtures thereof. The binder may include sodium carboxymethyl cellulose, mannitol, polyvinylpolypyrrolidone, microcrystalline cellulose, colloidal silicon dioxide, and combinations thereof.

The invention relates to a graft polyarylether (‘PAE’) copolymer (P1), a process for preparing the graft PAE copolymer (P1) from a side-chain allyl / vinylene-functionalized PAE copolymer (P0) via free radical reaction with vinyl pyrrolidone, and the use of the graft PAE copolymer (P1) in the preparation of an article, such as a membrane or a part thereof. The graft PAE copolymer (P1) comprises at least two types of recurring units, one of which having side-chain grafted poly(vinylpyrrolidone). The invention also relates to an amorphous side-chain allyl / vinylene-functionalized polyaryletherketone copolymer (P0).

The invention relates to a fabric fragrance-retaining material containing plant extracts and a preparation method of the fabric fragrance-retaining material, and aims to solve the problems of quick washing loss of fragrance and poor long-term effect in a traditional fabric fragrance-retaining technology. According to the material, a plant extract is used as a core material to prepare hydrophilic and hydrophobic biphase microspheres, a water-temperature dual-response polyvinyl pyrrolidone-N-isopropylacrylamide copolymer is used as a shell, and washing fragrance locking and dry-state temperature-sensitive fragrance release are realized by regulating and controlling swelling and shrinkage of a hydrophilic / hydrophobic segment. The microspheres are stably combined with fibers through the modified guar gum targeted adsorption layer and do not interfere with response, the fragrance retention rate after 40 times of water washing is 80%-90%, the fragrance retention time at the normal temperature is 60-90 days, and the fabric keeps the original hand feeling and air permeability.

The application belongs to the technical field of functional materials, and provides MOF-5, a preparation and application thereof, and a polymer self-lubricating composite material and a preparation and application thereof.A zinc salt, terephthalic acid, a capping agent (polyvinyl pyrrolidone or polyvinyl alcohol), a weak base (triethylamine or sodium acetate) and a solvent are mixed, and ultrasonic treatment is performed to obtain the MOF-5.The micro-morphology of the MOF-5 is in the form of a sheet layer, and the crystal face specificity is exposed by adding the capping agent and the weak base, so that the tribological performance can be improved when the MOF-5 is applied as a functional filler to a self-lubricating polymer.The MOF-5 mainly provides a reinforcing effect similar to that of crushed carbon fibers, and mainly acts as a bearing phase to bear the main load and contact the metal counterpart during the friction and wear process of the polymer self-lubricating composite material and the metal counterpart, and a uniform and continuous transfer film is formed on the surface of the metal counterpart, so that the tribological performance of the polymer self-lubricating composite material is improved.

The invention discloses a method for bonding a metal layer to a thermoplastic. The thermoplastic plastic comprises (a) polypropylene and (b) one or more of the following polar polymers: polyvinyl pyrrolidone, polypropylene acrylic acid, polyethylene acrylic acid, poly (vinyl alcohol), ethylene-vinyl alcohol, polypropylene acrylate, polyethylene acrylate, polypropylene methacrylate, polyethylene methacrylate, polyacrylic acid and polymethacrylic acid, the percentage of polar groups in one or more polar polymers is in the range of 5% to 100%. Articles comprising metallized thermoplastics are also disclosed.

The invention provides a pharmaceutical composition containing melogabalin besylate as an active ingredient. The pharmaceutical composition comprises the following components: melogabalin besylate, polyoxyethylene, polyvinylpolypyrrolidone, sodium alginate and mannitol, the mass ratio of the melogabalin benzene sulfonate to the polyoxyethylene to the polyvinylpolypyrrolidone to the sodium alginate to the mannitol is (0.5-8): (20-40): (5-15): (20-40): (3-20). The pharmaceutical composition is a sustained release preparation, and can ensure that melogabalin besylate is continuously released and absorbed in vivo, so that the drug effect is improved, the adverse reaction is reduced, and the treatment effect is enhanced while the administration frequency is reduced.

The invention discloses mangiferin / vanadium / PVP (Polyvinyl Pyrrolidone) composite nanoparticles as well as a preparation method and application thereof, and belongs to the field of nano medical materials. The composite nano particle disclosed by the invention is formed by self-assembling mangiferin, vanadium trichloride hexahydrate and polyvinyl pyrrolidone under the coordination action. The preparation method is simple and convenient, conditions are mild, the prepared nanoparticles are uniform in particle size, have good water dispersibility and photothermal conversion performance and have inherent bacteriostatic activity on various bacteria, and the antibacterial effect can be synergistically enhanced under irradiation of near-infrared light. The material has application prospects in the biomedical fields of antibiosis, photo-thermal therapy preparations and the like.

The invention discloses a preparation method of flake silver powder, which comprises the following steps: adding ammonia water into a silver nitrate solution to obtain a silver ammonia solution; adding stearic acid into the silver-ammonia solution to obtain a first mixed solution; and the first mixed solution and a hydroxylamine sulfate solution are added into a polyvinyl pyrrolidone solution containing copper nitrate, a primary stirring reaction is carried out, lauric acid is added for a secondary stirring reaction, cleaning, drying and powder mixing and ball milling are carried out, and then the flake silver powder is obtained. According to the invention, stearic acid and lauric acid are used for dual coating, copper nitrate is used for particle size adjustment, and stirring and ball-milling modes of a refining process are adopted, so that nucleation, growth and morphology of the flake silver powder are regulated and controlled, and the influence of environmental fluctuation on the quality of the silver powder is overcome; the prepared flake silver powder is high in morphology regularity, concentrated in particle size distribution, excellent in dispersity and small in batch difference, and then the tap density and the surface activity of the silver powder are improved.

The invention discloses a high-capacity wide-temperature-range vanadium redox flow battery electrolyte as well as a preparation method and application thereof, and belongs to the technical field of vanadium redox flow battery electrolytes. A multi-element synergistic system of a positive electrode zwitterionic additive, a negative electrode polyquaternium / poly (N-vinyl pyrrolidone) additive and ammonium phosphate is adopted, and the electrolyte performance of the positive electrode and the electrolyte performance of the negative electrode are improved at the same time. The positive electrode electrolyte is composed of a sulfuric acid system electrolyte containing V (IV) and V (V), a pyridyl alkyl sulphobetaine zwitterionic additive and ammonium phosphate; and the negative electrode electrolyte consists of a sulfuric acid system electrolyte containing V (II) and V (III) and a polyquaternium or poly (N-vinyl pyrrolidone) additive. Through the multi-element synergistic effect, V (V) high-temperature precipitation and V (II) / V (III) low-temperature crystallization are inhibited, vanadium ion transmembrane permeation can be reduced, the working temperature range is widened to-10 DEG C to 60 DEG C, the energy density is larger than or equal to 25 Wh / L, and the preparation method is simple and suitable for large-scale energy storage scenes.

The invention relates to a laundry detergent containing poly (N-vinyl pyrrolidone-co-methacrylic acid) and a preparation method thereof, and belongs to the technical field of laundry detergent production. The laundry detergent provided by the invention comprises the following components in percentage by mass: 0.05-0.2% of a chelating agent; 10 to 25% of an anionic surfactant; 0.5%-1.0% of a basifying agent; 1-8% of a nonionic surfactant; 0.1 to 0.5 percent of an antioxidant; 0.05 to 0.3 percent of preservative; 0.1 to 1.5 percent of poly (N-vinyl pyrrolidone-co-methacrylic acid); and the balance of deionized water. In practical application, the problem that a functional auxiliary agent is difficult to compound into a system or anions and cations are difficult to coexist can be solved to a certain extent by a method of directly adding the functional auxiliary agent into the formula system of the laundry detergent. In addition, by adding a low addition amount of the polymer into the laundry detergent product, the laundry detergent product can simultaneously provide three excellent and balanced properties of redeposition resistance, softness and fluffiness.

This invention discloses a high-capacity, wide-temperature-range vanadium redox flow battery electrolyte, its preparation method, and its application, belonging to the field of vanadium redox flow battery electrolyte technology. It employs a multi-component synergistic system consisting of a positive electrode zwitterionic additive, a negative electrode polyquaternary ammonium salt / polyN-vinylpyrrolidone additive, and ammonium phosphate, simultaneously improving the performance of both positive and negative electrode electrolytes. The positive electrode electrolyte is composed of a sulfuric acid electrolyte containing V(Ⅳ) and V(Ⅴ), a pyridylalkyl sulfobetaine zwitterionic additive, and ammonium phosphate; the negative electrode electrolyte is composed of a sulfuric acid electrolyte containing V(Ⅱ) and V(Ⅲ) and a polyquaternary ammonium salt or polyN-vinylpyrrolidone additive. Through the synergistic effect of these multiple components, high-temperature precipitation of V(Ⅴ) and low-temperature crystallization of V(Ⅱ) / V(Ⅲ) are suppressed, reducing vanadium ion transmembrane permeation, widening the operating temperature range to -10℃ to 60℃, achieving an energy density ≥25Wh / L, and the preparation method is simple, making it suitable for large-scale energy storage scenarios.

The application provides a gold-silver alloy nanoparticle and a preparation method and application thereof, and the preparation method comprises the following steps: reacting water, silver sulfide quantum dots and polyvinylpyrrolidone powder at 0 DEG C until the reaction is sufficient, centrifuging, and obtaining a silver sulfide supernatant; mixing chloroauric acid, a sodium citrate solution and a NaOH solution at room temperature until the reaction is sufficient, and obtaining a reaction liquid; mixing the obtained silver sulfide supernatant and the obtained reaction liquid, adding polyvinylpyrrolidone, adding a hydroxylamine hydrochloride solution and a NaOH solution in sequence after reaction, fully reacting, and obtaining gold-silver alloy ions; and purifying the obtained gold-silver alloy ions, so that the gold-silver alloy nanoparticle is obtained. The preparation method adopts an aqueous phase method to synthesize the gold-silver alloy nanoparticle, the synthesis process is simple, green and environment-friendly, and the synthesis means of the gold-silver alloy nanoparticle is enriched; and the gold-silver alloy nanoparticle has potential application in the research of Alzheimer's disease and can effectively inhibit the incorrect folding of A beta 40 protein.

Disclosed is an electrolyte membrane for a membrane electrode assembly, which can include a filler that is a polymer compound (oligomer) having a low molecular weight. The electrolyte membrane can suitably include an oligomeric poly(vinylpyrrolidone) compound having a sulfonic acid group. The electrolyte membrane for a membrane electrode assembly can have improved proton conductivity.

The application belongs to the technical field of natural gas exploitation, and particularly relates to an oil-resistant and freeze-resistant corrosion-inhibiting foaming agent for gas wells and a preparation method and application thereof. The oil-resistant and freeze-resistant corrosion-inhibiting foaming agent for gas wells comprises, in mass parts, 40-70 parts of sodium alpha-olefin sulfonate, 10-20 parts of cocamide propyl amine oxide, 1-10 parts of modified nanoparticles, 20-40 parts of betaine amphoteric ionic surfactant, 5-15 parts of corrosion inhibitor, 1-15 parts of polyvinyl pyrrolidone, and the balance of water. After aging at a low temperature of-30 DEG C, the foaming agent has a liquid carrying rate of up to 83.8% in a range of 10%-50% condensate content, a high resistance to salinity of up to 2*10<5> mg / L, and an inhibition rate of up to 75% in a composite sample liquid of 20 wt% condensate, 20 wt% methanol and saturated CO2. The foaming agent can meet the requirements of extreme composite working conditions such as high salinity, condensate pollution and acid gas corrosion in the middle and late stages of gas well development, and can realize the dual functions of drainage gas recovery and downhole protection.

The invention discloses a compound calcium supplement tablet and a preparation method thereof, the compound calcium supplement tablet comprises calcium carbonate, vitamin D3 microcapsules, a diluent, an adhesive and a disintegrating agent, the disintegrating agent is compounded by polyvinylpolypyrrolidone and croscarmellose sodium, and the obtained compound calcium supplement tablet has good stability and dissolution rate.

The invention discloses flower micro-capsule cleaning particle powder and a preparation method thereof. The particle powder comprises 30-40% of a carrier and forming agent, 30-45% of a surfactant, 5-15% of a conditioning and repairing agent, 5-12% of a disintegration and dissolution promoter, 3-8% of a core functional component and 1.5-3.0% of a fragrance protection micro-capsule agent. The carrier and the forming agent comprise corn starch, hydrophobic fumed silica and vitamin E; the surface active agent is prepared from sodium cocoyl isethionate, sodium methyl cocoyl taurate, coconut oil acyl propyl betaine and APG1214; the conditioning and repairing agent comprises a cationic conditioning agent, a humectant and a skin conditioning agent; the disintegration and dissolution promoter comprises polyvinylpolypyrrolidone, microcrystalline cellulose and a sodium bicarbonate-citric acid gas production pair; the core functional components comprise radiation-resistant composite enzyme powder and flower components. The product disclosed by the invention has the advantages of instant collapse when encountering water, abundant foam, lasting fragrance (not less than 36 hours), high active matter retention rate, stable color system, no chemical preservative, stable storage and the like. The invention further provides a cleaning and nursing article.