51 results about "Polyvinylpolypyrrolidone" patented technology

The invention relates to a sodium propionate-containing hydrate inhibitor for guaranteeing flow of a carbon dioxide conveying pipeline, which comprises sodium propionate, glycine, polyvinyl pyrrolidone and methanol, and the sodium propionate, the glycine, the polyvinyl pyrrolidone and the methanol are mixed with a sodium chloride solution serving as a solvent, so that the sodium propionate, the glycine, the polyvinyl pyrrolidone and the methanol are mixed according to the molar percentage as follows: 1-15 mol% of the sodium propionate, 1-15 mol% of the glycine, 0.1-1 mol% of the polyvinyl pyrrolidone and 5-60 mol% of the methanol. The sodium propionate, the glycine, the polyvinyl pyrrolidone and the methanol are compounded for use, so that the effect of a single inhibitor is enhanced, the application range is wider, a better inhibition effect is achieved at a lower concentration, and the generation of carbon dioxide hydrate can be better inhibited. The mixed use reduces the cost of the inhibitor, reduces the use amount of the mixture, and weakens the toxicity and pollution of the inhibitor.

The invention relates to a preparation method of an artificial blood vessel, the artificial blood vessel is composed of a porous support layer, a biodegradation layer and an antithrombotic layer, and the method comprises the following steps: soaking an expanded polytetrafluoroethylene substrate with silver nitrate doped polyvinyl pyrrolidone-poly-N-isopropylacrylamide to obtain the porous support layer; and then assembling a biodegradable material and an antithrombotic material as a biodegradable layer and an antithrombotic layer. The invention also relates to the artificial blood vessel prepared by the method.

The invention belongs to the technical field of natural gas extraction, and particularly relates to an oil-resistant anti-freezing corrosion-inhibition foaming agent for a gas well as well as a preparation method and application of the oil-resistant anti-freezing corrosion-inhibition foaming agent. The oil-resistant anti-freezing corrosion inhibition type foaming agent for the gas well is prepared from the following components in parts by mass: 40 to 70 parts of sodium alpha-olefin sulfonate, 10 to 20 parts of cocamidopropyl dimethylamine oxide, 1 to 10 parts of modified nanoparticles, 20 to 40 parts of betaine zwitterionic surfactant, 5 to 15 parts of corrosion inhibitor, 1 to 15 parts of polyvinyl pyrrolidone and the balance of water. After the foaming agent is aged at the low temperature of-30 DEG C, the liquid carrying rate of the foaming agent can be up to 83.8% in the range that the condensate oil content is 10%-50%, the degree of mineralization resistance is up to 2 * 10 mg / L, and the corrosion inhibition rate in a composite sample solution containing 20 wt% of condensate oil, 20 wt% of methanol and saturated CO2 can be up to 75% or above; the requirements of extreme composite working conditions of high salinity, gas condensate pollution and acid gas corrosion in the middle and later periods of gas well development can be met, and the dual effects of drainage gas recovery and underground protection are achieved.

This invention relates to the field of medical tape technology and discloses a medical tape and its preparation method, comprising the following steps: mixing polyvinylpyrrolidone, polyvinyl alcohol, antibacterial filler, glycerin and deionized water, stirring to obtain an antibacterial adhesive; coating the antibacterial adhesive onto the surface of a nonwoven fabric, drying to obtain an adhesive layer; and bonding a fabric substrate to the adhesive layer to obtain the medical tape. The antibacterial filler contains a composite antibacterial material with a multilayered antibacterial structure, exhibiting excellent antibacterial activity. Furthermore, the composite black phosphorus nanosheets are adhered between the layers, forming a composite layered material with high oxygen barrier properties, preventing black phosphorus from easily oxidizing upon contact with oxygen in the air, thus avoiding the loss of antibacterial activity of the medical tape. The formed composite layered material also possesses good mechanical properties, can weaken the stress in the tensile test of the medical tape, thereby distributing pressure, and has good flexibility.

The application discloses a rain night type road marking paint. The road marking paint is prepared from the following raw material components in parts by weight: modified acrylic emulsion 50-80 parts, polyvinylpyrrolidone 30-50 parts, curing agent 8-15 parts, wear-resistant agent 5-8 parts, glass microbead 30-50 parts, potassium feldspar powder 10-20 parts, antioxidant 3-5 parts, dispersing agent 3-6 parts, anti-sedimentation agent 3-5 parts, drying catalyst 1-3 parts, and toughening agent 2-5 parts. The road marking paint prepared by the application has good reflection performance in rain night and daytime; the combination use of the glass microbead and the potassium feldspar powder improves the retroreflective coefficient of the material; the combination use of the adipic dihydrazide and 3,3',4,4'-benzophenonetetracarboxylic dianhydride reduces the drying time; and the combination use of (3,3,3-trifluoropropyl)trimethoxysilane and potassium hexatitanate whisker improves the wear resistance of the material.

The invention discloses a preparation method for prolonging the validity period of erythromycin ethylsuccinate orally disintegrating tablets. The preparation method comprises the following steps: sequentially putting low-substituted hydroxypropyl cellulose, microcrystalline cellulose, aspartame, carboxymethyl starch sodium and polyvinylpolypyrrolidone into a wet granulation mixer, covering with a cover, starting equipment, carrying out low-speed dry mixing for 3 minutes, slowly adding low-concentration hydroxypropyl methylcellulose slurry from a feed port of a pot cover, and carrying out low-speed wet mixing for 3 minutes; stopping the machine, opening the cover, scraping powder on the inner surface of the pot cover and the periphery of the inner side of the pot by using a clean scraper, adding erythromycin ethylsuccinate raw materials, covering the cover, starting equipment, carrying out low-speed wet mixing for 3 minutes, and carrying out high-speed wet mixing for 2 minutes. By improving the medicine production process, the stability and durability of the medicine are improved, so that the validity period of the medicine is prolonged, and meanwhile, the effectiveness and safety of the medicine can still be kept within the prolonged validity period.

The application provides a palladium-zinc-bismuth oxide catalyst and a preparation method and application thereof in beta-hydroxy ester oxidation, and the preparation steps of the catalyst comprise the following steps: dissolving a bismuth salt and an alkali into water, adding carbon powder to be ultrasonically dispersed, then heating to reflux to perform reaction, and then performing filtration and drying to obtain Bi2O3 / C; dissolving a palladium salt, a zinc salt, L-ascorbic acid and polyvinyl pyrrolidone into water, adding Bi2O3 / C to be ultrasonically dispersed, then heating to reflux to perform reaction, and then performing filtration, drying and calcination to obtain the palladium-zinc-bismuth oxide catalyst. The obtained catalyst can be used in beta-hydroxy ester oxidation reaction, and beta-keto ester products can be obtained with high yield and high selectivity. The catalyst has novel structure, simple preparation process, can efficiently catalyze beta-hydroxy ester oxidation to obtain beta-keto ester products, has the advantages of fast reaction speed, high raw material conversion rate and high product selectivity, and has important application prospect.

The invention relates to the technical field of lithium battery diaphragms, in particular to a low-moisture and high-heat-resistance solution type acrylic acid binder and a preparation method thereof. Through the synergistic effect of the protective colloid composite cross-linking monomer, the low moisture content is achieved in a breakthrough mode. Wherein the steric hindrance effect of the polyvinyl alcohol in the protective colloid mixture inhibits exposure of hydrophilic groups, the polyvinyl pyrrolidone improves the dispersion stability, and the polyether polyol enhances the film-forming flexibility; hydroxyethyl acrylamide and diacetone methacrylamide in the crosslinking monomer mixture construct a dual crosslinking network, so that the covalent bond density between molecular chains is remarkably enhanced, and cyano groups of acrylonitrile further reduce the moisture adsorption path and improve the interface anchoring force through strong polarity and hydrophobicity; the three components cooperate with each other to achieve a heat-resistant effect which can only be achieved by a high addition amount in the prior art under a low addition amount, and meanwhile, the problem of diaphragm deformation caused by high-temperature long-time reaction is avoided.

The invention provides purpureocillium lilacinum for preventing and treating root rot and soil nematode diseases of food crops, a microbial inoculum and application of the purpureocillium lilacinum and the microbial inoculum. The name of the Purpureocillium lilacinus is Purpureocillium lilacinus HN-17, the Purpureocillium lilacinus HN-17 is classified and named as Purpureocillium lilacinus, the Purpureocillium lilacinus HN-17 is preserved in the China General Microbiological Culture Collection Center (CGMCC), and the preservation number is CGMCC No.41954. The Purpureocillium lilacinus HN-17 can be used for preparing the Purpureocillium lilacinus. Research results show that the antibacterial effect of the purpureocillium lilacinum HN-17 on 9 kinds of plant pathogenic bacteria such as fusarium oxysporum reaches 60.42%-83.33%; the indoor nematode killing effect on wheat cyst nematode and tomato root-knot nematode reaches 100%; the optimized binder, the optimized wetting agent, the optimized stabilizer and the optimized disintegrating agent are polyvinyl pyrrolidone, lauryl sodium sulfate, CaCO3 and AlCl3 respectively; the field control effects of wheat root rot and soybean root rot are 61.08% and 80.95% respectively after seed dressing and broadcasting, the field cyst decline rates of wheat cyst nematode and soybean cyst nematode are 54.61% and 66.67% respectively, and the application value is high.

The invention relates to the technical field of medical instrument coatings, and particularly provides a hydrophilic lubricating coating and a preparation process thereof, the hydrophilic lubricating coating comprises the following components by weight: 3%-10% of polyvinyl pyrrolidone, 5%-15% of composite bonding resin, 1%-5% of a cross-linking agent, 1%-5% of an initiator, 0.1%-1% of a leveling agent, 0.1%-0.5% of an antifoaming agent, 0.2%-2% of a nanometer reinforcing filler, and 60%-80% of a mixed solution; the preparation process comprises the following steps: preparing a presol, preparing a coating liquid, coating the coating liquid, carrying out thermocuring and carrying out UV photocuring. According to the invention, through collaborative design of the composite bonding resin and a gradient cross-linking system, strong adhesive force and lasting lubricity of the coating on a PVC substrate are realized; the mechanical strength and sterilization resistance of the coating are remarkably improved by introducing the nano reinforcing filler and the PVP with controllable molecular weight; according to the scheme, a dual-curing process is creatively used, and the forming quality of the hydrophilic lubricating coating is improved.

The invention belongs to the field of food, and particularly relates to direct drinking powder which comprises but is not limited to the following raw materials in parts by weight: 5-10 parts of coenzyme Q10 microcapsule powder, 1-3 parts of a white kidney bean probiotic fermentation extract, 2-5 parts of a pseudo-ginseng extract, 30-40 parts of a sweetening agent, 3-5 parts of polyvinylpolypyrrolidone, 1-2 parts of silicon dioxide, 1-2 parts of an acidity regulator and 0.5-1 part of edible essence. The instant powder disclosed by the invention has the characteristics of melting within 3 seconds in the mouth, no need of being taken after being mixed, fine and fresh in mouth feel, high in bioavailability and strong in stability, not only effectively solves the problems of solubility and stability of fat-soluble active ingredients, but also realizes dual absorption of the fat-soluble active ingredients in oral mucosa and gastrointestinal tracts, and improves the nutritional and health-care effects of the instant powder.

The invention discloses a preparation method of hypercrosslinked macroporous adsorption resin for removing cytokines in blood purification. Macroporous styrene-divinylbenzene resin with low crosslinking degree is prepared from styrene and divinylbenzene, then secondary crosslinking is performed on the macroporous styrene-divinylbenzene resin with the low crosslinking degree by utilizing a Friedel-Grafts method to prepare the hypercrosslinked adsorption resin, residual chloromethyl reacts with enamine to generate dangling double bonds, and then the hypercrosslinked adsorption resin is prepared. And then, polyvinyl pyrrolidone and poly (hydroxyethyl methacrylate) are grafted. The hypercrosslinked adsorption resin prepared by the invention has a huge specific surface area and abundant pore channels, and has superstrong adsorption performance on cell factors represented by TNF-alpha and IL-6, and in addition, polyvinyl pyrrolidone and poly (hydroxyethyl methacrylate) are grafted on the surface of the resin, so that the blood compatibility is improved.

The application relates to a sodium propionate hydrate inhibitor containing sodium propionate for carbon dioxide conveying pipeline flow guarantee, which comprises sodium propionate, glycine, polyvinyl pyrrolidone and methanol, and the molar percentage of the four after being mixed with a sodium chloride solution as a solvent is as follows: 1-15mol% of sodium propionate, 1-15mol% of glycine, 0.1-1mol% of polyvinyl pyrrolidone and 5-60mol% of methanol. In the application, the composite use of sodium propionate, glycine, polyvinyl pyrrolidone and methanol enhances the effect of a single inhibitor, the use range is more extensive, better inhibiting effect can be achieved at a lower concentration, and the generation of carbon dioxide hydrate can be better inhibited. The mixed use reduces the cost of the inhibitor, reduces the use amount of the mixture and weakens the toxicity and pollution of the inhibitor.

The present disclosure provides coated optical articles that exhibit anti-fog properties. The coated article comprises: (1) an optical substrate; and (2) a coating applied as a topmost layer over the surface of the substrate. The coating is formed from a treatment composition comprising: (A) a polymer comprising a carboxylic acid group, a pyrrolidone group, and an alkoxysilane group; (B) an alkoxysilane containing an amino functional group, an ammonium functional group, an epoxy functional group, or an ethylenically unsaturated group; and (C) polyvinyl pyrrolidone.

The application provides a method for preparing an ultralubricating coating by a "in situ transplanting method", which coats a natural rubber medical catheter with a synthetic polyisoprene solution. Since the synthetic polyisoprene has the same composition as the natural rubber, the interface of the two is firmly combined and the coating does not fall off. An azo initiator opens the double bond in the polyisoprene molecule under ultraviolet light irradiation, and further initiates the polymerization of a vinyl pyrrolidone monomer, so that polyvinyl pyrrolidone side chain molecular brushes grow on the polyisoprene molecular chain, like seedlings growing in a field. The polyvinyl pyrrolidone molecular brushes with ultralubricating effect are firmly combined on the surface of the natural rubber medical catheter, and the purpose of ultralubricating and drag reduction is achieved. The method can prevent the allergic reaction caused by trace amounts of protein in the natural rubber, and can effectively increase the lubricity of the natural rubber medical catheter and reduce the surface friction.

The present invention relates to solid oral care compositions, such as tablets, comprising a binder system. In certain aspects, the present invention relates to solid oral care compositions comprising a binder system, wherein the binder system comprises polyvinylpyrrolidone and hydroxyethylcellulose, as well as tablets, to the use of these compositions and to methods of manufacturing these compositions.

The invention provides a remegapam sulfate orally disintegrating tablet and a preparation method thereof, and the remegapam sulfate orally disintegrating tablet is prepared from an active component remegapam sulfate orally disintegrating tablet, a filler mannitol and microcrystalline cellulose, a disintegrating agent polyvinylpolypyrrolidone, an adhesive low-substituted hydroxypropyl cellulose, a flavoring agent sucralose and a lubricant magnesium stearate. The problems of poor material flowability, sticking, easy cracking during tabletting and the like during tabletting are solved, the tablet has the advantages of rapid disintegration, rapid dissolution, better compressibility, better stability, good taste, simple preparation method and the like, is more suitable for patients with dysphagia, especially the old and children, has great clinical significance, and is worthy of popularization and application. The method is suitable for large-scale industrial production.

The invention discloses a method for efficiently extracting polyphenol substances in olive juice by recycling PVPP (Polyvinyl Pyrrolidone). The method comprises the following steps: 1) adding water into the pulp of fresh olive fruits, pulping, and adding pectinase and cellulase for enzymolysis; (2) squeezing the olive pulp subjected to enzymolysis to obtain juice, filtering, centrifuging, and collecting crude olive extract supernate; (3) adding the crude olive extract supernatant into the swollen PVPP until the final concentration of the PVPP is 5%, stirring, adsorbing, standing, centrifuging, and discarding the supernatant to obtain PVPP precipitate adsorbed with olive polyphenol; 4) carrying out desorption on the PVPP precipitate adsorbed with the oleuropein by using an elution solvent, and separating used PVPP and a desorption solution containing the oleuropein; according to the method, the PVPP is recycled to extract the polyphenols, the polyphenol substances are obtained through desorption, adsorption and purification, clarified fruit juice is obtained at the same time, and waste recycling is achieved.

The invention relates to the technical field of tooth socket cleaning, in particular to a cleaning composition for effectively removing tooth socket calcification deposits and a preparation method of the cleaning composition. The cleaning composition is prepared from the following raw materials in parts by weight: 80-90 parts of citric acid, 20-30 parts of potassium peroxymonosulfate, 10-20 parts of sodium phytate, 10-20 parts of sodium pyrophosphate, 10-20 parts of polyvinylpolypyrrolidone, 15-25 parts of sorbitol, 5-7 parts of a foaming agent, 2-4 parts of a coloring agent, 1-2 parts of a bitter agent, 8-12 parts of a bactericide and 2-4 parts of a lubricating agent. In the invention, glycerol, sodium hydroxide and deionized water are treated to generate an alkaline environment to play a role in activating a material, a porous carrier can be formed after furfural residue and silicone oil are subsequently added for treatment, and formic acid treatment can expand a pore structure by etching and enhance the adsorption capacity of the carrier, so that the adsorption capacity of the carrier is improved in subsequent copper chloride solution treatment. The cleaning composition can continuously release low-concentration copper ions to interfere with the enzyme activity of bacteria, so that an efficient antibacterial effect is achieved.

Provided is a current collector for a power storage device for obtaining a low-resistance power storage device. A current collector for a power storage device, characterized by having a coating layer formed on one or both surfaces of a sheet-shaped conductive substrate, the coating layer containing a powdered carbon material, acid-modified poly(1,1-difluoroethylene), and polyvinylpyrrolidone, the content of the polyvinylpyrrolidone in the coating layer being 0.099 to 5.0 mass%, and the content of the powdered carbon material in the coating layer being 15.0 to 45.0 mass%.

The invention provides a melogabalin besylate sustained release preparation. The melogabalin besylate sustained release preparation is prepared from the following components: melogabalin besylate, polyoxyethylene, polyvinylpolypyrrolidone, sodium alginate and microcrystalline cellulose, the mass ratio of the melogabalin besylate to the polyoxyethylene to the polyvinylpolypyrrolidone to the sodium alginate to the microcrystalline cellulose is (0.5-8): (20-40): (5-15): (20-40): (6-35). The sustained release preparation can ensure that melogabalin besylate is continuously released and absorbed in vivo, so that the drug effect is improved, the adverse reaction is reduced and the treatment effect is enhanced while the administration frequency is reduced.

The invention provides PRP gel poor in leucocyte and low in pro-inflammatory risk as well as a preparation method and application of the PRP gel, and belongs to the field of PRP gel. The method comprises the following steps: S1, under a high vacuum condition, mixing acrylate resin, a surface modified nano silicon dioxide composite material, polyether modified polysiloxane and polyvinyl pyrrolidone to obtain PRP separation gel; s2, collecting peripheral blood by using a vacuum blood collection tube with a built-in PRP (platelet rich plasma) separation gel, and centrifuging to obtain platelet rich plasma on an interface of the PRP separation gel; s3, mixing and activating the platelet-rich plasma and an initiator to obtain the PRP gel. The precise density gradient is constructed by customizing the thixotropic separation gel, efficient layered isolation of platelets, pro-inflammatory leukocytes and erythrocytes is achieved, the high-concentration platelets are accurately enriched, meanwhile, the leukocyte content is greatly reduced, and therefore PRP products with controllable components and stable effects are achieved, and the repairing requirements of sensitive environments such as uterine cavities are met.

The present invention relates to a seed coating composition containing a polymeric binder, a filler and a fibrous material. A seed coating composition can be formed by combining an aqueous composition premix containing a polymeric binder with a powder premix containing a filler and a fibrous material. The polymer binder preferably contains polyvinyl pyrrolidone, the filler preferably contains talc, and the fibrous material preferably contains cellulose fibers.

In the preparation process, mannitol and microcrystalline cellulose are used as filling agents, polyvinylpolypyrrolidone and low-substituted hydroxy propyl cellulose are used as disintegrating agents, and aspartame and menthol are used as taste masking agents, so that the problems of poor material fluidity, sticking, easiness in cracking during tabletting and the like are solved; by adopting a direct tabletting method, the adverse effect of high temperature and high humidity on the selexipag is reduced, and the selexipag tablet has the advantages of rapid disintegration within 30 seconds, rapid dissolution, better compressibility, better stability, good taste, simple preparation method and the like, is more suitable for patients with dysphagia, especially the old and children, has great clinical significance and is worthy of popularization and application. The method is suitable for large-scale industrial production.

The invention discloses a broad-spectrum antibacterial drug which comprises a tablet core and a coating film, the tablet core comprises 500-1000 parts of levofloxacin, 50-100 parts of a diluent, 30-100 parts of a disintegrating agent, 5-30 parts of an adhesive and 10-54 parts of a lubricant, and the coating film is a gastric-soluble film coating; wherein the disintegrating agent is a compound of carboxymethyl cellulose, polyvinylpolypyrrolidone and croscarmellose sodium; the broad-spectrum antibacterial drug tablet obtained in the invention has good dissolution rate and stability, and can be rapidly disintegrated.

The invention discloses a preparation method of an efficient ethylamine pyrazine rifo tablet. The preparation method comprises the following steps: (1) preparing isoniazide, pyrazinamide, microcrystalline cellulose and pregelatinized starch into isoniazide particles; mixing ethambutol hydrochloride, microcrystalline cellulose and pregelatinized starch to prepare ethylamine particles; (2) spraying and adding an aqueous solution of povidone K30 into the iso-tobacco particles to obtain an iso-tobacco soft material, spraying and adding a mixed aqueous solution of povidone K30 and lauryl sodium sulfate into ethylamine particles to prepare an ethylamine soft material, granulating, drying and finishing the particles to obtain dry ethylamine particles; and (3) mixing and stirring the ethylamine dry granules, talcum powder and rifampicin, then adding corn starch, the iso-tobacco dry granules, polyvinylpolypyrrolidone and magnesium stearate, uniformly mixing, tabletting and coating to obtain a finished product. By optimizing the preparation process, the disintegration time of the tablet is shortened, the dissolution of active ingredients of the medicine is accelerated, and the medicine effect of the medicine is improved. In addition, by preparing the rifampicin clathrate compound, the solubility of rifampicin can be remarkably improved, and the drug property is improved.

The invention belongs to the technical field of pharmaceutical preparations. The invention discloses a preparation method of a dapagliflozin tablet. The preparation method mainly comprises the following steps: mixing dapagliflozin anhydride which is micronized until D90 is less than or equal to 30 microns with filling agents such as microcrystalline cellulose and lactose; carrying out wet granulation by using a hydroxypropyl methylcellulose aqueous solution as an adhesive; performing fluidized bed low-temperature drying on the particles until the moisture is less than or equal Adding polyvinylpolypyrrolidone as an external disintegrating agent and a magnesium stearate lubricant for total mixing after size stabilization; and finally, forming by adopting a prepressing and main pressing combined tabletting process. According to the dapagliflozin tablet and the preparation method thereof, the technical problems of low dissolution rate caused by poor solubility of dapagliflozin, poor content uniformity, increase of related substances, poor process robustness and the like which are easily caused by a conventional process are effectively solved by accurately controlling the particle size of raw material medicines, the type and concentration of an adhesive, a drying mode and a tabletting process. The prepared tablet is similar to a reference preparation in dissolution behavior, stable in quality attribute and suitable for industrial production.

The disclosure provides tablets for a mouthrinse containing fluoride, an effervescent agent comprising an acid and a base, a water soluble lubricant, a binder, and a sensory modifying agent. The tablets are free of preservatives and free et alcohol. In certain embodiments, the effervescent agent contains citric acid and sodium bicarbonate. The water soluble lubricant may include polyethylene glycol (PEG), potassium sorbate, sodium benzoate, calcium sorbate, PEG with one or more of trisodium citrate, calcium ascorbate, and mixtures thereof. The binder may include sodium carboxymethyl cellulose, mannitol, polyvinylpolypyrrolidone, microcrystalline cellulose, colloidal silicon dioxide, and combinations thereof.

The invention relates to a graft polyarylether (‘PAE’) copolymer (P1), a process for preparing the graft PAE copolymer (P1) from a side-chain allyl / vinylene-functionalized PAE copolymer (P0) via free radical reaction with vinyl pyrrolidone, and the use of the graft PAE copolymer (P1) in the preparation of an article, such as a membrane or a part thereof. The graft PAE copolymer (P1) comprises at least two types of recurring units, one of which having side-chain grafted poly(vinylpyrrolidone). The invention also relates to an amorphous side-chain allyl / vinylene-functionalized polyaryletherketone copolymer (P0).

The invention relates to a fabric fragrance-retaining material containing plant extracts and a preparation method of the fabric fragrance-retaining material, and aims to solve the problems of quick washing loss of fragrance and poor long-term effect in a traditional fabric fragrance-retaining technology. According to the material, a plant extract is used as a core material to prepare hydrophilic and hydrophobic biphase microspheres, a water-temperature dual-response polyvinyl pyrrolidone-N-isopropylacrylamide copolymer is used as a shell, and washing fragrance locking and dry-state temperature-sensitive fragrance release are realized by regulating and controlling swelling and shrinkage of a hydrophilic / hydrophobic segment. The microspheres are stably combined with fibers through the modified guar gum targeted adsorption layer and do not interfere with response, the fragrance retention rate after 40 times of water washing is 80%-90%, the fragrance retention time at the normal temperature is 60-90 days, and the fabric keeps the original hand feeling and air permeability.