28 results about "Nanoshell" patented technology

This invention discloses a material with high photothermal conversion efficiency, its preparation method, and its application in neural modulation, belonging to the field of biomedical technology. In this method, liquid metal is ultrasonically spun into nanoscale particles. Using these liquid metal nanoparticles as templates, hollow nanoshells composed of ultra-small metal nanoparticles can be prepared through an electrocoupling reaction with a metal salt. This method is simple, easy to operate, and applicable to various metals. The prepared material with high photothermal conversion efficiency has a hollow structure, a rough surface, and pores. This unique structure endows it with a strong photon trapping ability, significantly enhancing light absorption and exhibiting ultra-high photothermal conversion efficiency. This invention allows for the injection of this material into the nerve, utilizing its excellent photothermal effect for rapid and precise neural modulation, thereby achieving effective prevention and treatment of autonomic nervous system-related diseases, and showing promising application prospects.

The invention relates to the technical field of magnetic particle imaging, in particular to a core-shell nanoprobe and a preparation method and application thereof.The core-shell nanoprobe comprises a magnetic core and a nanoshell which is located outside the magnetic core and has a magnetic shielding response function, and the structure of the nanoshell collapses under the tumor microenvironment condition; the saturation magnetization of the magnetic core is greater than or equal to 50 emu / g, and the coercive force is less than or equal to 5 Oe; the saturation magnetization of the nano shell is less than 50 emu / g, and the coercive force is more than 5 Oe. According to the core-shell nanoprobe, through a unique magnetic core-shell structure design and tumor microenvironment response characteristics, a magnetic shielding layer is formed by using a low-signal nano shell with a response magnetic shielding function, and background signal interference is inhibited. In a tumor microenvironment, the shell structure of the core-shell nanoprobe collapses, the magnetic core is exposed, and a high magnetic signal is released and generated, so that the imaging signal-to-noise ratio is remarkably improved. According to the invention, the bottleneck that the traditional MPI probe is lighted in the whole course can be broken through, the tumor specificity is lighted and positioned, and the problems that the external background of the tumor is high, the contrast ratio is poor, and tiny focuses are difficult to detect are solved.

A micro-separator for gas chromatography includes a base substrate having a trench defining a micro-column, and a three-dimensional (3D) porous ceramic-polymer composite disposed in the micro-column and having pores that three-dimensionally connected to each other with periodicity. The 3D porous ceramic-polymer composite includes a ceramic nano-structure, which forms an array of three-dimensionally arranged nano-shells, and a reaction-activating layer combined on a surface of the ceramic nano-structure and including a polymeric reaction-activating material. A thickness of the 3D porous ceramic-polymer composite is 10 μm to 20 μm, a column length of the 3D porous ceramic-polymer composite is 30 cm to 70 cm, and a shell thickness of the ceramic nano-structure is 20 nm to 60 nm. The micro-separator may have improved separation performance and durability.

The invention relates to the field of carbon-loaded nano-catalysts, in particular to a one-dimensional zigzag ultrathin Pt-based nano-shell catalyst which is coated on a carbon nanotube and has abundant defects and a preparation method of the one-dimensional zigzag ultrathin Pt-based nano-shell catalyst. According to the catalyst, a carbon nanotube film is used as a substrate, magnetron sputtering is carried out at room temperature, then rapid annealing is carried out, and finally a one-dimensional zigzag ultrathin Pt-based nano shell is formed and uniformly coats a carbon nanotube bundle. The ultrathin Pt-based nano shell has abundant surface structures (high-index edge steps) and a large number of crystal defects such as twin crystals and stacking faults, the electronic structure of surface atoms is adjusted, and the adsorption / desorption strength of an intermediate is optimized, so that the catalytic activity is influenced. According to the method, efficient and controllable preparation of the defect type Pt-based nanowire catalyst is achieved, the activity and stability of the catalyst are improved, the method can be suitable for various catalytic reactions related to fuel cells, and the method is expected to be a practical method for large-scale preparation and application of the catalyst.

The invention provides a covalent organic framework spaced plasma enhanced fluorescent nano composite material as well as a preparation method and application thereof, and relates to the technical field of nano materials and biological detection. The material sequentially comprises a SiO2 nanosphere core, an Au nano shell layer, a covalent organic framework layer and a carboxylated quantum dot layer from inside to outside, wherein the covalent organic framework layer comprises a Schiff base type covalent organic framework formed by connecting 1, 3, 5-tri (4-aminophenyl) benzene and 2, 5-dimethoxy terephthalaldehyde through a carbon-nitrogen double bond; the thickness of the covalent organic framework layer is 3 to 24 nm; wherein the carboxylated quantum dot layer is prepared from CdSe / ZnS-COOH particles. The rigid spacing material which is stable in structure and capable of accurately regulating and controlling the thickness is constructed and is used for constructing a stable and controllable spatial distance between the metal nanoparticles and the fluorophor, so that plasma enhanced fluorescence is realized, and the immunochromatography detection performance is improved.

The invention belongs to the field of biomedical metal materials, and discloses medical Ta-xTi alloy high-quality powder for additive manufacturing and a preparation method of the medical Ta-xTi alloy high-quality powder, and the powder is prepared from titanium powder, tantalum powder, a tantalum-doped titanium nitride coated amorphous carbon nano shell, yttrium-stabilized zirconium oxide coated mesoporous silicon dioxide nano particles and stearic acid according to a specific weight part ratio. The preparation process comprises the following steps: firstly, uniformly adsorbing nano tantalum powder and two modified compounds on the surface of micron-sized titanium powder through an electrostatic self-assembly technology to form core-shell structure composite powder; and then the composite powder is subjected to spheroidizing treatment through radio frequency plasma, and finally the high-quality alloy powder with the high sphericity degree and the good fluidity is obtained. According to the method, the problems of composition segregation and unmelted particles of high-melting-point tantalum and titanium in the selective laser melting forming process are solved, meanwhile, the material is endowed with lower elastic modulus and enhanced biological activity and antibacterial performance, and the method is particularly suitable for manufacturing high-performance customized bone implants.

The application discloses a magnetic nanoparticle for enriching flavonoids and a preparation method and application thereof, wherein the magnetic nanoparticle comprises a magnetic core formed by ferroferric oxide and a nanoshell covering at least part of the surface of the magnetic core, wherein the nanoshell is composed of repeated polybasic ring units, and the polybasic ring unit has the following formula (I). The magnetic nanoparticle can be used for rapid and efficient purification and enrichment of flavonoids in food, and has the advantages of high efficiency, small dosage, good stability, large adsorption capacity, easy separation and the like.

The invention relates to the technical field of copper powder preparation, and provides a preparation method of liquid-phase in-situ self-assembly nano-shell-coated micron-core composite copper powder, a specific inducer is introduced into a liquid-phase reduction system, copper sulfate is adopted as a copper salt, and sodium hypophosphite or VC is adopted as a reducing agent, so that one-time forming of a micron-core-nano-shell composite structure is realized; the problems of non-uniform particle size distribution, high energy consumption, low yield and the like in a traditional copper powder preparation method are effectively solved; according to the prepared composite copper powder, the low-temperature sintering driving force brought by the nanometer shell layer is obtained while the process-friendly characteristics of being easy to filter, easy to wash, easy to dry and the like of micron powder are reserved, the initial sintering temperature can be reduced to about 150 DEG C, and the machining performance of the copper powder under the low-temperature condition is remarkably improved.

The application provides a metal-loaded transition metal oxide-transition metal chalcogenide composite material and a preparation method and application thereof, a transition metal chalcogenide nanoshell is wrapped on the surface of a transition metal oxide nanoparticle to form a core-shell structure, and metal microparticles are loaded on the surface of the transition metal chalcogenide nanoshell, the metal microparticles are single atoms, nanoclusters or nanocrystals. The composite material has double active sites of metal and chalcogen vacancies, and the nanoshell and the metal microparticles are closely combined at a molecular scale, so that the core-shell structure composite material has lower overpotential, smaller Tafel slope and impedance, larger surface active area and better durability when used as an electrocatalyst for electrocatalytic HER. The application solves the problem that pH restricts electrocatalytic HER of a transition metal chalcogenide, provides an atomic-level design strategy for preparing a high-efficiency full-pH electrocatalyst, and has important significance for promoting sustainable hydrogen production by water electrolysis.

The invention belongs to the technical field of functional composite materials, and particularly relates to a graphene-coated silicon carbide hollow microsphere composite heat-conducting filler and a preparation method and application thereof.The graphene-coated silicon carbide hollow microsphere composite heat-conducting filler comprises silicon carbide hollow microspheres and graphene layers evenly coated on the surfaces of the silicon carbide hollow microspheres, the particle size of the silicon carbide hollow microspheres is 15-30 micrometers, the wall thickness is 1.0-2.2 micrometers, and the graphene layers are evenly coated on the surfaces of the silicon carbide hollow microspheres. The hollow rate is 60%-75%, the number of the graphene layers is 2-5, and the density of the composite heat-conducting filler is 0.8-1.2 g / cm < 3 >; the silicon carbide hollow microspheres are of a beta-phase cubic system structure, the grain size is 50-80 nanometers, the density of a shell layer is 95% or above, the density of the silicon carbide hollow microspheres is only 0.8-1.2 g / cm < 3 > and is reduced by 62.5%-75% compared with 3.2 g / cm < 3 > of solid silicon carbide, and the weight of the composite material can be reduced by 38%-45% under the same heat-conducting property.

The application discloses a kind of bifunctional hybrid type plasmonic sensor, including substrate, metal film, dielectric grating and metal nanoshell array;The metal film is evaporated on the substrate;The dielectric grating is located between the metal film and the metal nanoshell array;The metal nanoshell array is with the dielectric grating as template, and is inclined and evaporated on the surface of the dielectric grating;The metal film and the metal nanoshell array are coupled to form plasmon mode under the action of incident light wave.The bifunctional hybrid type plasmonic sensor is based on superstructure grating, RA and LSPR are fully coupled, and the intensity of coupling signal is fully played by controlling the angle of incident light.Thereby it can be used to detect the small change of external environment refractive index, and also can detect the small change of local refractive index generated by the combination of virus antibody and antigen adsorbed on the surface of structure.

The application belongs to the field of biomedical metal materials, and discloses a high-quality medical Ta-xTi alloy powder for additive manufacturing and a preparation method thereof. The powder is composed of titanium powder, tantalum powder, tantalum-doped titanium nitride coated amorphous carbon nanoshell, yttrium-stabilized zirconium coated mesoporous silica nanoparticles and stearic acid in a specific weight ratio. In the preparation process, first, nanometer tantalum powder and two modified compounds are uniformly adsorbed on the surface of micron-sized titanium powder through electrostatic self-assembly technology to form a core-shell structure composite powder; then, the composite powder is spheroidized by radio frequency plasma, and finally, high-quality alloy powder with high sphericity and good fluidity is obtained. The method solves the problems of composition segregation and unmelted particles of high-melting-point tantalum and titanium in the laser selective melting forming process, and at the same time, the method endows the material with lower elastic modulus and enhanced biological activity and antibacterial performance, and is particularly suitable for manufacturing high-performance customized bone implants.

Methods of forming magnetic / plasmonic hybrid structures are disclosed. The methods include synthesizing colloidal magnetic nanoparticles; modifying the magnetic nanoparticles in a solution of polymeric ligands; binding metal seed nanoparticles to the surface of the magnetic nanoparticles; and performing seed-mediated growth on the metal seed nanoparticles by reducing a metal salt in solution to form the magnetic / plasmonic hybrid structures.

The invention discloses an anti-TPM-4 targeting gold / silver nanoshell molecular probe as well as a preparation method and application thereof, and belongs to the technical field of targeting and imaging molecular materials. The molecular probe prepared by the invention has a hollow and porous structure, can entrap drugs, can specifically bind to TPM-4 highly expressed in cells of tumors and the like, has high stability, and can be used for targeted drug-loading treatment of diseases of tumors and the like; the nano-material has intracellular electrocatalytic activity, can be used for imaging cells such as tumors, and is expected to provide assistance for real-time observation and monitoring of cells such as tumors; the hydrogel has no cytotoxicity / very low cytotoxicity, has no electrical stimulation toxicity, has good biocompatibility, and can be trustingly applied in an organism; the provided preparation method is simple and easy to operate, no toxic or harmful substance is generated, and the requirement for equipment is low.

The invention discloses a nanoscale sandwich confinement structure SiO2 (at) CuO (at) Al2O3 oxygen carrier and a preparation method and application thereof.CuO serves as an active component to provide lattice oxygen for chemical looping combustion, SiO2 microspheres with gully fold structures on the surfaces serve as carriers to increase the specific surface area and form confinement anchoring sites, CuO particles are separated, and the specific surface area is increased; meanwhile, an ultrathin sandwich core-shell confinement structure is accurately constructed through an atomic layer deposition technology, an ultrathin nano Al2O3 shell layer guarantees gas diffusion, active site coverage is avoided, the high-temperature environment is isolated to inhibit CuO high-temperature migration while the efficient mass transfer efficiency is guaranteed, the confinement effect is also achieved, and the service life of the device is prolonged. Migration and agglomeration of CuO particles are inhibited through the double confinement effect of gullies in the surfaces of the SiO2 microspheres and the nano Al2O3 shell layer, and the carrier-metal oxide-carrier sandwich structure with the nanoscale space double confinement effect achieves remarkable improvement of the stability in the oxidation reduction process of the oxygen carrier.

The invention relates to a single cell in-situ packaging method, and belongs to the technical field of cell engineering and biology. The single cell in-situ packaging method comprises the following steps: S1, carrying out reduction treatment on cells by adopting a tris (2-carboxyethyl) phosphine solution with the pH value of 7.0-8.0, so that part of free sulfydryl on the surfaces of the cells is exposed; s2, sequentially incubating the cells treated in the step S1 by adopting a four-arm polyethylene glycol acrylate solution and a sulfydryl polyethylene glycol solution under a normal temperature condition, forming a covalent cross-linked hydrogel nano-shell through a Michael addition reaction initiated by sulfydryl exposed on the surface, uniformly coating the surface of a single cell with the nano-shell, and drying to obtain the covalent cross-linked hydrogel nano-shell. The packaged cells are obtained. According to the method, a stable, shape-preserving and covalent cross-linked hydrogel nano shell can be directly formed on a cell membrane under mild physiological conditions, and damage to cells in the packaging process is avoided.

This invention discloses a method for preparing surface-modified spherical hollow nanoshell NiS and its application, relating to inorganic non-metallic materials and their application in the field of passive interference technology. The prepared surface-modified spherical hollow nanoshell NiS can be used as a novel passive smoke screen interference material. Its particle surface is hydrophobically modified, making it less prone to agglomeration and exhibiting good flow properties, thus improving the compatibility of the product with equipment in practical applications. Its crystal configuration and unique hollow structure give it strong absorption and scattering capabilities. The nanometer thickness of the hollow spherical structure can excite the small size effect and quantum size effect of the material, and it has high extinction capabilities in the visible light and near-mid-far infrared bands. Compared with traditional smoke screen interference materials, it has great performance advantages, and the preparation process is simple, efficient, and low in cost.

The disclosure relates to particle-based assays for the detection of analytes. Using various combinations of particular technologies, including gold nanorods, silver nanoparticles, gold / silver nanoshells, gold / silver nanocages and nanobubble detection, enhanced detection limits can be achieved across a large range of analytes.

The invention belongs to the technical field of biomolecule detection, and particularly relates to composite sol, an electrode and a preparation method and application thereof. The composite sol comprises an hAu-Ru nano shell and poly (3-hexylthiophene); wherein the hAu-Ru nano shell contains Au and Ru elements and is in a hollow sphere shape, the diameter of the hAu-Ru nano shell ranges from 20 nm to 50 nm, and the shell thickness ranges from 5 nm to 10 nm. The biocompatibility and the stability of the CFME modified based on the composite sol, and the anti-interference capability, the selectivity, the sensitivity and the detection limit of ascorbic acid detection are obviously superior to those of the CFME modified based on the composite sol.

The invention relates to an MCMBs (at) SiC combined silicon carbide friction material and a preparation method thereof. The preparation method of the MCMBs (at) SiC combined silicon carbide friction material comprises the following steps: mixing silicon carbide coated mesocarbon microbeads MCMBs (at) SiC powder with SiC powder, and drying to obtain mixed powder; the mixed powder is put into a mold to be subjected to hot pressing sintering, and the MCMBs-coated SiC combined silicon carbide friction material is obtained. The silicon carbide nano-shell structure formed by the molten salt method has good affinity with the silicon carbide powder mixed with the silicon carbide nano-shell structure in the high-temperature sintering process, so that the bonding strength of two phases is improved, and the wear rate of the friction material is reduced.

The application discloses a kind of near-infrared two-zone small molecule photothermal agent based on quinone structure and its preparation method and application, belong to the field of biological medicine.The photothermal agent by introducing quinone structure, significantly improve the light absorption and photothermal conversion efficiency in NIR-II window, suitable for 1064nm wavelength photothermal treatment.Its preparation method includes multi-step organic synthesis reaction, finally obtain dark brown solid BPT-FNC.In addition, the application also provides a kind of nano aggregate preparation method, by polymer nanoshell coating small molecule photothermal agent, enhance its biocompatibility and tumor targeting.The nano aggregate has application potential in the preparation of tumor photothermal treatment reagent.Experimental results show that BPT-FNC NAs under 1064nm laser irradiation shows excellent photothermal performance and biological safety, can induce cell pyroptosis and activate immune response, provides innovative solution for deep tumor treatment.

The invention relates to a preparation method of a nano fluorescent probe for detecting heavy metal ions in a liquid sample, and belongs to the field of chemical detection. The preparation method is a chemical synthesis method and comprises the following steps: firstly, carrying out dehydration condensation on a tetradentate amine monomer (TBDT) and a linear dialdehyde monomer (BCBA) under the action of a catalyst, then carrying out ultrasonic treatment, degassing, vacuum sealing, high-temperature reaction and other series operations to prepare a covalent organic framework (TB-BA COF) material taking a solid terbium-benzoic acid complex as a construction unit, and finally, washing and extracting to obtain the covalent organic framework material. The purified nano fluorescent probe of the covalent organic framework (TB-BA COF) material with the artificial antibody terbium-benzoic acid complex as a construction unit for selectively recognizing and detecting the heavy metal ions is obtained. The nano shell layer on the surface of the nanosphere not only increases the specific surface area of the polymer, but also enables all recognition sites to be located on the surface of the nano shell layer, so that the number, binding quantity and selectivity of the recognition sites are increased.

The invention provides an electromagnetic shielding polyurethane porous fiber membrane with a sandwich structure and a preparation method thereof. The porous fiber membrane comprises a middle dielectric-electromagnetic synergistic layer and surface conductive layers laminated on two sides of the middle dielectric-electromagnetic synergistic layer, the middle dielectric-electromagnetic synergistic layer is of a double-layer shell layer structure in which a polyaniline nano shell layer and a layered dihydroxy oxide layer are sequentially generated on the surface of the polymer fiber membrane; the surface conductive layer is a conductive network formed by growing metal nanoparticles on the surface of the polymer fiber membrane; and the polymer fiber membrane is a polyurethane fiber membrane. According to the invention, a'reflection-absorption-re-reflection 'multi-reflection closed-loop mechanism is formed through the hierarchical design of'surface conducting layer-intermediate dielectric-electromagnetic synergistic layer-surface conducting layer' and the porous fiber interlocking structure, so that secondary reflection pollution is remarkably reduced. The high-frequency electromagnetic shielding material has the advantages that the shielding performance of the high-frequency electromagnetic shielding material is improved, interlayer fiber fusion interlocking and pore reserving are achieved through hot pressing, the average shielding effectiveness in the X wave band (8.2-12.4 GHz) is 60-90 dB, the performance attenuation is smaller than or equal to 5% after 1000 times of bending, and the high-frequency electromagnetic shielding material is suitable for 5G communication and wearable equipment high-frequency electromagnetic protection.

The invention provides noble metal-free electro-catalyst compositions for use in acidic media, e.g., acidic electrolyte. The noble metal-free electro-catalyst compositions include non-noble metal absent of noble metal. The non-noble metal is non-noble metal oxide, and typically in the form of any configuration of a solid or hollow nano-material, e.g., nano-particles, a nanocrystalline thin film, nanorods, nanoshells, nanoflakes, nanotubes, nanoplates, nanospheres and nanowhiskers or combinations of myriad nanoscale architecture embodiments. Optionally, the noble metal-free electro-catalyst compositions include dopant, such as, but not limited to halogen. Acidic media includes oxygen reduction reaction (ORR) in proton exchange membrane (PEM) fuel cells, and direct methanol fuel cells and oxygen evolution reaction (OER) in PEM-based water electrolysis and metal air batteries, and hydrogen generation from solar energy and electricity-driven water splitting.

The invention provides noble metal-free electro-catalyst compositions for use in acidic media, e.g., acidic electrolyte. The noble metal-free electro-catalyst compositions include non-noble metal absent of noble metal. The non-noble metal is non-noble metal oxide, and typically in the form of any configuration of a solid or hollow nano-material, e.g., nano-particles, a nanocrystalline thin film, nanorods, nanoshells, nanoflakes, nanotubes, nanoplates, nanospheres and nanowhiskers or combinations of myriad nanoscale architecture embodiments. Optionally, the noble metal-free electro-catalyst compositions include dopant, such as, but not limited to halogen. Acidic media includes oxygen reduction reaction (ORR) in proton exchange membrane (PEM) fuel cells, and direct methanol fuel cells and oxygen evolution reaction (OER) in PEM-based water electrolysis and metal air batteries, and hydrogen generation from solar energy and electricity-driven water splitting.

The invention discloses a photo-thermal response type multifunctional intelligent antibacterial composite material, the composite material comprises a hydrogel carrier and composite nanoparticles dispersed in the hydrogel carrier, and the hydrogel carrier is constructed and formed by SFMA and OHA through a dynamic covalent cross-linking effect; each composite nanoparticle comprises a nano core and a silver nano shell layer coating the surface of the nano core; the nano core is formed by self-assembly of metformin hydrochloride and EGCG through a phenol-amine condensation reaction, and the silver nano shell layer is composed of silver nanoparticles generated by an in-situ reduction reaction of silver ions on the surface of the nano core. The metformin hydrochloride and EGCG synergistically regulate and control inflammation and oxidative stress in a diabetes microenvironment, broad-spectrum antibiosis is achieved with the help of the silver nano shell layer, drug release is accelerated under near-infrared light irradiation, and the material is used for local treatment of chronic infectious wounds such as diabetic periodontitis and the like and has a wide application prospect. The dilemma of insufficient coordinated regulation of triple pathologies of diabetes and periodontitis at present is solved, and the staged treatment requirement of the wound surface can be accurately met.

The application belongs to the technical field of functional composite materials, and particularly relates to a graphene-coated silicon carbide hollow microsphere composite heat-conducting filler, a preparation method and application thereof, which comprises silicon carbide hollow microspheres and a graphene layer uniformly coated on the surfaces of the silicon carbide hollow microspheres, the particle size of the silicon carbide hollow microspheres is 15-30 microns, the wall thickness is 1.0-2.2 microns, the hollow rate is 60%-75%, the number of layers of the graphene layer is 2-5 layers, and the density of the composite heat-conducting filler is 0.8-1.2 g / cm3; the silicon carbide hollow microspheres have a beta-phase cubic crystal structure, the grain size is 50-80 nm, the shell layer density is more than 95%, the density of the silicon carbide hollow microspheres is only 0.8-1.2 g / cm3, which is reduced by 62.5%-75% compared with 3.2 g / cm3 of solid silicon carbide, and the weight of the composite material can be reduced by 38%-45% under the same heat-conducting performance.

The invention discloses spherical silver powder with a nanometer shell layer structure and a preparation method and application of the spherical silver powder. The method comprises the following steps: simultaneously adding an oxidant solution accounting for 30-35% of the total mass of the oxidant solution and a reducing agent solution accounting for 30-35% of the total mass of the reducing agent solution into a dispersant solution to obtain a first reaction solution; simultaneously adding the residual reducing agent solution and an oxidant solution which accounts for 20-65% of the total mass of the oxidant solution into the first reaction solution to obtain a second reaction solution; adding the rest oxidant solution accounting for 5-45% of the total mass of the oxidant solution into the second reaction solution to obtain a third reaction solution; and the coating agent solution is added into the third reaction solution, then stirring, solid-liquid separation, cleaning and drying are conducted, and the spherical silver powder of the nanometer shell structure is obtained. According to the invention, the problems of difficult printing and agglomeration caused by high specific surface area of nano-silver particles are greatly reduced; the method is simple to operate, low in cost and suitable for industrial production.