This invention discloses an improved reservoir-type
vaginal ring. The
drug is loaded as a
drug-carrying core by mixing it with
silicone rubber, and the core is coated with a controlled-release layer made of pure
silicone rubber. The
drug-carrying core contains a developing agent and a dispersant. The developing agent includes
barium sulfate,
titanium dioxide, iodotram, iodofol,
iopromide, iodophenylhexamol, and iodophenyl ester. The dispersant includes
methyl silicone oil, phenyl
silicone oil, vinyl
silicone oil,
hydrogen-containing
silicone oil, and glycerin. This invention combines the advantages of existing
extrusion and molding methods, effectively controlling the size and regularity of the drug-carrying core of the reservoir-type
vaginal ring, ensuring stable and controllable
drug content. It can effectively improve the product deformation problems caused by
cutting, external force, and hot-pressing
vulcanization processes in existing co-
extrusion processes.