1 results about "Iohexol" patented technology

This invention belongs to the field of biomedical materials technology, and discloses a one-step chitosan-grafted iohexol self-illuminating microsphere, its preparation method, and its applications. The microsphere uses chitosan, a natural biocompatible material, as the carrier framework, iohexol as the self-illuminating functional component, and genipin, a natural extract, as the cross-linking agent. A one-step grafting and cross-linking curing process is used to form self-illuminating microspheres with uniform particle size and stable structure. These microspheres exhibit clear imaging under X-rays and also possess good biocompatibility, biodegradability, and sustained-release properties, making them widely applicable in medical fields such as tumor embolization therapy and tissue engineering tracing, achieving integrated diagnosis and treatment. The preparation process of this invention is simplified, requiring no multi-step reactions, with mild control conditions, and is easy for industrial production, solving the problems of complex preparation, poor biocompatibility, and imbalance between imaging and biological properties in traditional self-illuminating materials.