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649results about How to "Eliminate effective" patented technology

FcGammaRIIB Specific Antibodies and Methods of Use Thereof

InactiveUS20090074771A1Strong therapeutic activityEnhancing antibody-mediated effector functionAntibody ingredientsImmunoglobulinsTolerabilityImmune complex deposition
The present invention relates to antibodies or fragments thereof that specifically bind FcγRIIB, particularly human FcγRIIB, more particularly the extracellular domain of FcγRIIB with greater affinity than said antibodies or fragments thereof bind FcγRIIA, particularly human FcγRIIA, and block the Fc binding site of FcγRIIB. The present invention also encompasses the use of an anti-FcγRIIB antibody or an antigen-binding fragment thereof, as a single agent therapy for the treatment, prevention, management, or amelioration of a cancer, preferably a B-cell malignancy, particularly, B-cell chronic lymphocytic leukemia or non-Hodgkin's lymphoma, an autoimmune disorder, an inflammatory disorder, an IgE-mediated allergic disorder, or one or more symptoms thereof. The present invention also encompasses the use of an anti-FcγRIIB antibody or an antigen-binding fragment thereof, in combination with other cancer therapies. The present invention provides pharmaceutical compositions comprising an anti-FcγRIIB antibody or an antigen-binding fragment thereof, in amounts effective to prevent, treat, manage, or ameliorate a cancer, such as a B-cell malignancy, an autoimmune disorder, an inflammatory disorder, an IgE-mediated allergic disorder, or one or more symptoms thereof. The invention further provides methods of enhancing the therapeutic effect of therapeutic antibodies by administering the antibodies of the invention to enhance the effector function of the therapeutic antibodies. The invention also provides methods of enhancing efficacy of a vaccine composition by administering the antibodies of the invention with a vaccine composition. The invention further provides methods of treating cancer and/or regulating immune complex-mediated cell activation by administering the antibodies of the invention to enhance an immune response. The invention also provides methods of breaking tolerance to an antigen by administering an antigen-antibody complex and an antibody of the invention.
Owner:MACROGENICS INC

Preparation method of supported metal catalyst

The invention discloses a preparation method and application of a supported metal catalyst. The supported metal catalyst comprises carrier framework materials and nano particles, loaded on the surfaces of the carrier framework materials, of metal or metal oxide, or metal ions chelated on the surfaces of the carrier framework materials, wherein the metal ions and nano particles of the metal or metal oxide are loaded on the surfaces of the carrier framework materials through the polymerization layers, adhered to the surfaces of the carrier framework materials, of catechol derivatives. The preparation method of the supported metal catalyst has the advantages that the method is simple, various carrier framework materials are used, one or more metal ions or nano particles can be loaded, and universality is achieved; the supported metal catalyst is good in active metal dispersity, large in carrier specific surface area, low in use amount, low in cost, and the like; the catalyst loaded with noble metal is catalyst material which is widely used and environmental friendly and is efficiently applicable to environmental chemical engineering fields such as dye wastewater decoloring, wastewater organic pollutant removing, car tail gas treatment, air purification, hydrogenation and reforming catalytic reaction, gas sensors and fuel cells.
Owner:YANTAI INST OF COASTAL ZONE RES CHINESE ACAD OF SCI

Method and system for display manipulation of multiple applications in a data processing system

A method and system for manipulating the display of multiple software applications within a data processing system which are displayed within multiple windows which at least partially overlap in a selected order from a bottom position to a top position. A depth control window is displayed within the data processing system in response to a user input. The depth control window includes multiple graphic elements arranged in the selected order wherein each graphic element corresponds to a software application window within the data processing system. The display of software application windows within the data processing system is then altered, in response to a user selection of a particular graphic element, to display a particular application window which corresponds to the selected graphic element and each window which is overlapped by the window displaying the particular application. In this manner, the user may efficiently "dive" to a selected depth within an overlapping stack of windows and effectively eliminate from the display those windows which are "above" the selected window, without rearranging the hierarchical order of the windows. The depth control window also includes graphics controls which permit a user to alter the graphic appearance of a selected window within the data processing system.
Owner:IBM CORP

Interference elimination system and method based on pre-equalization

ActiveCN103200140AReduce channel multipath effectsReduce orderTransmitter/receiver shaping networksSelf adaptiveBroadband
The invention relates to an interference elimination system and method based on pre-equalization and belongs to the field of communication and signal processing. At a receiving end, a received signal is divided into two paths, one path signal is sent to an interference elimination self-adapting filter and serves as an input signal of the interference elimination self-adapting filter, the other path signal is sent to a pre-equalization computing module, weight is computed by the pre-equalization computing module according to the received signal or a channel estimated value, and the computed weight is enabled to be sent to a pre-equalizer of an interference emission end. At the interference emission end, an emission signal is divided into two paths, one path signal serves as a referential signal and is sent to the interference elimination self-adapting filter at the receiving end, the other path signal is sent to the pre-equalizer, and pre-equalization processing is carried out on the emission signal by the pre-equalizer and then the emission signal is sent out. Compared with a traditional interference elimination method, the interference elimination method is capable of simplifying work of the interference elimination self-adapting filter and effectively eliminating broadband self-interference signals.
Owner:北京和宽科技有限公司
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