The invention relates to the technical field of vacuum defoamation, and discloses a vacuum defoamation device used for producing a high-polymer material. The vacuum defoamation device used for producing the high-polymer material comprises a tank, wherein a material inlet is formed in the top of the tank, a material outlet is formed in the bottom of the tank, the material inlet and the material outlet are connected through a circulation mechanism, and a defoamation and mixing mechanism is fixedly connected with the tank; and the defoamation and mixing mechanism comprises a driving motor, a rotating shaft, inclined defoamation layers, a reciprocating screw, a ball nut and a mixing board, the driving motor is fixedly connected with the center of the upper end of the tank, a rotating hole is formed in the center of the upper end of the tank, one end of the rotating shaft is connected with an output end of the driving motor through a coupler, the end, away from the driving motor, of the rotating shaft penetrates through the rotating hole, and extends into the tank, the inclined defoamation layers are installed on the rotating shaft, and one end of the reciprocating screw is connected with the end, away from the driving motor, of the rotating shaft. By means of the vacuum defoamation device used for producing the high-polymer material, the high-polymer material in the tank is fully mixed and stirred, so that the defoamation efficiency is improved.