6 results about "Ethylene Dibromide" patented technology

This invention provides a method for preparing Centhaquine, a drug for treating hemorrhagic shock. Specifically, the preparation method provided by this invention includes the following steps: (S1) providing compound II and compound IV; wherein compound II is prepared by the following method, which includes the steps of: (A) reacting compound I with 1,2-dibromoethane in a first solvent in the presence of base 1 to obtain compound II; and compound IV is prepared by the following method, which includes the steps of: (B) reacting compound III with pinacol diborate in a second solvent in the presence of Grignard reagent to obtain compound IV; (S2) preparation of compound A; and reacting compound II and compound IV in a third solvent in the presence of a catalyst and base 2 to obtain Centhaquine. The preparation method of this invention has a simple and safe synthetic route and operation, readily available raw materials, simple post-processing, high yield, and is suitable for industrial production.

The invention relates to an imidazole bromide azobenzene ionic liquid catalyst as well as a synthesis method and application thereof. According to the technical scheme, the preparation method comprises the following steps: diazotizing 2, 6-diethylaniline at 0-5 DEG C, and then carrying out coupled reaction on the diazotized 2, 6-diethylaniline and 3, 5-dimethyl sodium phenolate to obtain 4-hydroxy-2, 6-dimethyl-2 ', 6'-diethylazobenzene; the preparation method comprises the following steps: carrying out a nucleophilic substitution reaction on 4-bromoethoxy-2, 6-dimethyl-2 ', 6'-diethylazobenzene and 1, 2-dibromoethane to obtain an intermediate 4-bromoethoxy-2, 6-dimethyl-2 ', 6'-diethylazobenzene; and finally, reacting the intermediate with excessive N-methylimidazole to synthesize the imidazole bromide azobenzene ionic liquid catalyst, namely 4-(N-methylimidazole bromide)-ethoxy-2, 6-dimethyl-2 ', 6'-diethyl azobenzene. The method has the characteristics of simple synthesis method, good water solubility of the catalyst, short reaction time at room temperature, high catalytic efficiency, green and environment-friendly catalytic reaction with water as a solvent, easy separation of products, recyclability of the catalyst and the like.

This invention discloses a method for preparing deuterated 1,2-dibromoethane, comprising the following steps: (1) adding tetradeuterium glycol, N-bromosuccinimide, and solvent into a reaction vessel; (2) controlling the temperature inside the reaction vessel at -5 to 20°C, and then adding a mixture of triphenylphosphine and solvent dropwise into the reaction vessel; (3) after the dropwise addition is completed, restoring the reaction vessel to room temperature, and controlling the reaction time to 0.5 to 1.5 h to obtain a product containing deuterated 1,2-dibromoethane. The reaction temperature of this invention is at room temperature, the reaction operation is simple, it meets the requirements of green chemistry, and it can be industrialized. Furthermore, the purity of deuterated 1,2-dibromoethane is above 98 wt%, and the yield of deuterated 1,2-dibromoethane is above 60 wt%.

The invention relates to the field of non-woven fabrics, and discloses a water-repellent breathable non-woven fabric and a preparation method thereof.The non-woven fabric is prepared from modified polyester fibers and natural fibers through needling, and the modified polyester fibers and the natural fibers are prepared from polyester chips and modified nano titanium dioxide through melt spinning; the modified nano titanium dioxide is prepared by grafting a silicon-containing quaternized cardanol derivative on the surface of nano titanium dioxide; the silicon-containing quaternized cardanol derivative is prepared by the following steps: reacting brominated epoxy cardanol ether prepared by reacting epoxidized cardanol with 1, 2-dibromoethane with N-methylimidazole, then reacting the obtained epoxy quaternized cardanol with a modified silane coupling agent, and then reacting the obtained silicon-containing epoxy quaternized cardanol with chitosan. And the modified silane coupling agent is prepared from gamma-methacryloxypropyltrimethoxysilane and tetramethyldisiloxane through a reaction. The non-woven fabric prepared by the method has excellent mechanical properties, water repellency, air permeability, antibacterial property, high temperature resistance and wear resistance.

The application relates to the field of non-woven fabrics, and discloses a water-repellent and breathable non-woven fabric and a preparation method thereof. The non-woven fabric is made of modified polyester fibers and natural fibers, wherein the modified polyester fibers are made of polyester chips and modified nano titanium dioxide melt spinning; the modified nano titanium dioxide is made by grafting a silicon quaternary ammoniumized cardanol derivative on the surface of nano titanium dioxide; the silicon quaternary ammonized cardanol derivative is made by reacting bromo-epoxy cardanol ether obtained by reacting epoxidized cardanol and 1,2-dibromoethane with N-methyl imidazole, then reacting the obtained epoxy quaternary ammonized cardanol with a modified silane coupling agent, and then reacting the obtained silicon-containing epoxy quaternary ammonized cardanol with chitosan; the modified silane coupling agent is made by reacting gamma-methacryloxypropyl trimethoxysilane with tetramethyldisiloxane, and the non-woven fabric prepared by the application has excellent mechanical properties, water-repellent and breathable properties, antibacterial properties, high-temperature resistance and wear resistance.

The invention belongs to the technical field of electrochemical energy storage, and relates to a complex additive with a bis-imidazolium structure as well as a preparation method and application of the complex additive. The method comprises the following steps: dissolving 1-(2-ethoxyl) imidazole and anhydrous potassium carbonate in anhydrous acetonitrile, and stirring to obtain a 1-(2-ethoxyl) imidazole acetonitrile solution; under the protection of nitrogen, dropwise adding 1, 2-dibromoethane into the 1-(2-ethoxyl) imidazole acetonitrile solution, and carrying out heating reflux reaction to obtain a reaction mixture; cooling and filtering the reaction mixture, and collecting filtrate; mixing the filtrate with ethyl acetate, and separating out a solid product A; washing, evaporating and drying the solid product A to obtain the complexing additive with the bis-imidazolium structure. The invention solves the problems of low coulombic efficiency and poor cycle stability of the zinc-bromine flow battery caused by bromine volatilization and shuttle effect in the prior art, and the problems of performance degradation of the traditional complexing agent in high and low temperature environments, easy phase separation of the electrolyte and poor low temperature fluidity.