16 results about "Ethylene Dibromide" patented technology

This invention provides a method for preparing Centhaquine, a drug for treating hemorrhagic shock. Specifically, the preparation method provided by this invention includes the following steps: (S1) providing compound II and compound IV; wherein compound II is prepared by the following method, which includes the steps of: (A) reacting compound I with 1,2-dibromoethane in a first solvent in the presence of base 1 to obtain compound II; and compound IV is prepared by the following method, which includes the steps of: (B) reacting compound III with pinacol diborate in a second solvent in the presence of Grignard reagent to obtain compound IV; (S2) preparation of compound A; and reacting compound II and compound IV in a third solvent in the presence of a catalyst and base 2 to obtain Centhaquine. The preparation method of this invention has a simple and safe synthetic route and operation, readily available raw materials, simple post-processing, high yield, and is suitable for industrial production.

The invention relates to an imidazole bromide azobenzene ionic liquid catalyst as well as a synthesis method and application thereof. According to the technical scheme, the preparation method comprises the following steps: diazotizing 2, 6-diethylaniline at 0-5 DEG C, and then carrying out coupled reaction on the diazotized 2, 6-diethylaniline and 3, 5-dimethyl sodium phenolate to obtain 4-hydroxy-2, 6-dimethyl-2 ', 6'-diethylazobenzene; the preparation method comprises the following steps: carrying out a nucleophilic substitution reaction on 4-bromoethoxy-2, 6-dimethyl-2 ', 6'-diethylazobenzene and 1, 2-dibromoethane to obtain an intermediate 4-bromoethoxy-2, 6-dimethyl-2 ', 6'-diethylazobenzene; and finally, reacting the intermediate with excessive N-methylimidazole to synthesize the imidazole bromide azobenzene ionic liquid catalyst, namely 4-(N-methylimidazole bromide)-ethoxy-2, 6-dimethyl-2 ', 6'-diethyl azobenzene. The method has the characteristics of simple synthesis method, good water solubility of the catalyst, short reaction time at room temperature, high catalytic efficiency, green and environment-friendly catalytic reaction with water as a solvent, easy separation of products, recyclability of the catalyst and the like.

The invention discloses a preparation method of a 4-(allyl)-4-methyl-1, 1 '-biphenyl liquid crystal monomer, which comprises the following steps: S1, by taking p-phenylboronic acid, dechlorobenzyl alcohol, Pd / Cl and sodium carbonate as raw materials, reacting for 1-12 hours in a toluene and water system under the protection of nitrogen to obtain 4'-methyl-[1, 1 '-biphenyl]-4-benzyl alcohol (intermediate 1); s2, taking the intermediate 1 and hydrochloric acid as raw materials, and petroleum ether, toluene or ethanol as a solvent to obtain 3-(chloromethyl)-4 '-methyl-1, 1'-biphenyl (intermediate 2); s3, finally, chloropropene, the intermediate 2, magnesium particles and dibromoethane are used as raw materials, and tetrahydrofuran, petroleum ether or methylbenzene is used as a solvent; according to the present invention, the target compound is synthesized by using the existing raw materials and the technical equipment, such that the use amount of the catalyst is small, the catalytic efficiency is high, and compared with the hydrogen bromide, the corrosion on the equipment is weak, the conversion rate is high, the yield is high, the post-treatment process is simple, and the cost is reduced and the effect is improved.

This invention discloses a method for preparing deuterated 1,2-dibromoethane, comprising the following steps: (1) adding tetradeuterium glycol, N-bromosuccinimide, and solvent into a reaction vessel; (2) controlling the temperature inside the reaction vessel at -5 to 20°C, and then adding a mixture of triphenylphosphine and solvent dropwise into the reaction vessel; (3) after the dropwise addition is completed, restoring the reaction vessel to room temperature, and controlling the reaction time to 0.5 to 1.5 h to obtain a product containing deuterated 1,2-dibromoethane. The reaction temperature of this invention is at room temperature, the reaction operation is simple, it meets the requirements of green chemistry, and it can be industrialized. Furthermore, the purity of deuterated 1,2-dibromoethane is above 98 wt%, and the yield of deuterated 1,2-dibromoethane is above 60 wt%.

The present disclosure provides a method to form 1,2-dibromoethane in an electrochemical reactor system. The electrochemical reactor system comprises an electrochemical cell having an anode, an anolyte, a cathode, a catholyte and a membrane, an anode compartment and a cathode compartment, wherein the anolyte is an aqueous solution comprising at least 20 mM bromide salt. The method comprises the steps of introducing carbon dioxide into the cathode compartment; applying a potential to the cathode, and allowing an electrochemical reaction to proceed forming reduction products at the cathode and oxidation products at the anode; and bringing the reduction products in contact with the oxidation products externally from the electrochemical cell and allowing the reduction products to react with the oxidation products to form 1,2-dibromoethane.

The invention discloses a preparation method capable of improving the yield of trifluoroethylene, which comprises the following steps: in the presence of an organic solvent, mixing 1-chloro-1, 2-dibromo-1, 2, 2-trifluoroethane, a metal dehalogenating agent and an activating agent for reaction, then cooling and dropwise adding water into the reaction system to obtain trifluoroethylene, the activating agent is 1, 2-dibromo-1, 2, 2-trifluoroethane, and the metal dehalogenating agent is 1, 2-dibromo-1, 2, 2-trifluoroethane. The catalyst is selected from at least one of 1, 2-dibromoethane, bromoethane and dichloroethane. An activating agent is added into a reaction system, the activating agent serves as an efficient initiator, the activating agent is heated to decompose and release free radicals, the free radicals reduce oxides on the surface of a metal dehalogenating agent, reaction active sites of the metal dehalogenating agent are exposed, reaction of 1-chloro-1, 2-dibromo-1, 2, 2-trifluoroethane and the metal dehalogenating agent is facilitated, and the metal dehalogenating agent can be used for dehalogenating 1-chloro-1, 2-dibromo-1, 2, 2-trifluoroethane. Therefore, the conversion rate of the reaction is effectively improved, and the yield of trifluoroethylene is improved.

The invention provides an imidazole cobalt complex and a preparation method and application thereof, and the preparation method of the imidazole cobalt complex comprises the following steps: step 1, adding substituted imidazole and 1, 2-dibromoethane into a first solvent, carrying out water bath heating reaction to obtain a turbid liquid, filtering to obtain a precipitate, and recrystallizing the precipitate; step 2, mixing the precipitate with cobalt salt, adding a second solvent into the mixture, and carrying out heating reflux reaction; and after the reaction is finished, filtering, washing and drying to obtain the imidazole cobalt complex. The imidazole cobalt complex has the advantages of stable steric configuration, mild reaction conditions, high catalytic performance and the like, the synthesis process is simple, the central metal is cheap and easy to obtain, and industrial production is easy to realize. The imidazole cobalt complex disclosed by the invention has a good application prospect and large-scale popularization potential in the field of catalytic oxidation of dimethylnaphthalene reaction.

The invention discloses a preparation method of an azobenzene structure-containing surfactant and application of the azobenzene structure-containing surfactant in emulsion polymerization, and the preparation method comprises the following steps: carrying out diazotization reaction on 4-aminodiphenyl ether and fluorine-containing phenol or phenol to obtain 4-phenoxy azobenzene, then reacting the 4-phenoxy azobenzene with 1, 2-dibromoethane to remove hydrogen bromide to generate an intermediate, and carrying out emulsion polymerization to obtain the azobenzene structure-containing surfactant. And carrying out addition reaction on the obtained intermediate and trimethylamine, and purifying. The prepared azobenzene-containing surfactant is novel in structure, and compared with a traditional azobenzene-containing surfactant, the azobenzene-containing surfactant can achieve reversible conversion between cis-isomers and trans-isomers under irradiation of visible light with different wavelengths, and the problem that demulsification is tedious in a traditional emulsion polymerization process can be solved.

The invention relates to the field of non-woven fabrics, and discloses a water-repellent breathable non-woven fabric and a preparation method thereof.The non-woven fabric is prepared from modified polyester fibers and natural fibers through needling, and the modified polyester fibers and the natural fibers are prepared from polyester chips and modified nano titanium dioxide through melt spinning; the modified nano titanium dioxide is prepared by grafting a silicon-containing quaternized cardanol derivative on the surface of nano titanium dioxide; the silicon-containing quaternized cardanol derivative is prepared by the following steps: reacting brominated epoxy cardanol ether prepared by reacting epoxidized cardanol with 1, 2-dibromoethane with N-methylimidazole, then reacting the obtained epoxy quaternized cardanol with a modified silane coupling agent, and then reacting the obtained silicon-containing epoxy quaternized cardanol with chitosan. And the modified silane coupling agent is prepared from gamma-methacryloxypropyltrimethoxysilane and tetramethyldisiloxane through a reaction. The non-woven fabric prepared by the method has excellent mechanical properties, water repellency, air permeability, antibacterial property, high temperature resistance and wear resistance.

The application discloses a kind of two-dimensional electrocatalytic hydrogen evolution materials based on cation-π interaction construction and preparation method and application, specifically related to the field of catalyst, including multiple two-dimensional electrocatalytic hydrogen evolution monomers, multiple two-dimensional electrocatalytic hydrogen evolution monomers are connected head to tail between, the preparation method of monomer includes: 4,4'-dihydroxy azobenzene, bromoaromatic hydrocarbon, tetrabutylammonium iodide and cesium carbonate are coupled to obtain product;Product, 1,2-dibromoethane, cesium carbonate are etherified to obtain R2-bromoazobenzenyl compound;R2-bromoazobenzenyl compound, aromatic cation are subjected to nucleophilic substitution reaction, and ammonium hexafluorophosphate solution is added to carry out anion exchange reaction, to obtain R1-ethoxy-phenyl-azo-phenyloxy-ethyl-R2-hexafluorophosphate salt.Can significantly increase the exposure of hydrogen adsorption active site, thereby significantly improve the electrocatalytic hydrogen evolution performance.

The invention relates to a class of amphiphilic BODIPY derivatives containing azophenyl groups and a preparation method thereof. 4,4'-dibromoethane azobenzene and 1,7-bis(4-hydroxyphenyl)-3,5-bis(4-propynyloxy) azamethylenedipyrrole are reacted to obtain an azamethylenedipyrrole containing an azophenyl group. The azamethylenedipyrrole containing an azophenyl group is reacted under the action of boron trifluoride etherate to obtain a BODIPY mother core containing an azophenyl group. Benzamide containing a hydrophilic chain R is introduced into the BODIPY mother core structure containing an azophenyl group through a click reaction to obtain an amphiphilic Aza-BODIPY dye containing an azophenyl group, with the structural formula shown below. This series of molecules introduces a light-responsive azophenyl group for the first time, completes a self-assembly process for control, and has the characteristics of mild properties and low cost, thereby providing a new approach for achieving in vitro simulation of life systems.

The application relates to the field of non-woven fabrics, and discloses a water-repellent and breathable non-woven fabric and a preparation method thereof. The non-woven fabric is made of modified polyester fibers and natural fibers, wherein the modified polyester fibers are made of polyester chips and modified nano titanium dioxide melt spinning; the modified nano titanium dioxide is made by grafting a silicon quaternary ammoniumized cardanol derivative on the surface of nano titanium dioxide; the silicon quaternary ammonized cardanol derivative is made by reacting bromo-epoxy cardanol ether obtained by reacting epoxidized cardanol and 1,2-dibromoethane with N-methyl imidazole, then reacting the obtained epoxy quaternary ammonized cardanol with a modified silane coupling agent, and then reacting the obtained silicon-containing epoxy quaternary ammonized cardanol with chitosan; the modified silane coupling agent is made by reacting gamma-methacryloxypropyl trimethoxysilane with tetramethyldisiloxane, and the non-woven fabric prepared by the application has excellent mechanical properties, water-repellent and breathable properties, antibacterial properties, high-temperature resistance and wear resistance.

The invention discloses loaded long-chain fluorine-containing aryl borate as well as a preparation method and application thereof. The preparation method comprises the following steps: A, reacting an amine compound and hydrochloric acid in a solvent to generate quaternary ammonium salt; b, (4-bromophenoxy) alkylsilane, magnesium chips and 1, 2-dibromoethane are heated in a solvent for a reaction, and a Grignard reagent is generated; c, reacting the Grignard reagent with perfluoroaryl borane in the presence of a solvent to generate fluorine-containing aryl borate; d, the fluorine-containing aryl borate and quaternary ammonium salt react in a solvent to generate long-chain fluorine-containing aryl borate; e, reacting the silicon dioxide subjected to heat treatment with silane and triethylamine in a solvent to generate silane modified silicon dioxide; f, enabling the long-chain fluorine-containing aryl borate and the silane modified silicon dioxide to generate loaded long-chain fluorine-containing aryl borate in the presence of a solvent; by using the loaded long-chain fluorine-containing aryl borate, the activity of the catalyst, the molecular weight of the polymer and the insertion rate of a comonomer can be improved; in addition, the loaded long-chain fluorine-containing aryl borate can use aluminum alkyl with low price, so that expensive MAO / MMAO is avoided, and the production cost is reduced.

The invention belongs to the technical field of electrochemical energy storage, and relates to a complex additive with a bis-imidazolium structure as well as a preparation method and application of the complex additive. The method comprises the following steps: dissolving 1-(2-ethoxyl) imidazole and anhydrous potassium carbonate in anhydrous acetonitrile, and stirring to obtain a 1-(2-ethoxyl) imidazole acetonitrile solution; under the protection of nitrogen, dropwise adding 1, 2-dibromoethane into the 1-(2-ethoxyl) imidazole acetonitrile solution, and carrying out heating reflux reaction to obtain a reaction mixture; cooling and filtering the reaction mixture, and collecting filtrate; mixing the filtrate with ethyl acetate, and separating out a solid product A; washing, evaporating and drying the solid product A to obtain the complexing additive with the bis-imidazolium structure. The invention solves the problems of low coulombic efficiency and poor cycle stability of the zinc-bromine flow battery caused by bromine volatilization and shuttle effect in the prior art, and the problems of performance degradation of the traditional complexing agent in high and low temperature environments, easy phase separation of the electrolyte and poor low temperature fluidity.

The invention discloses a synthesis method of resin containing amino functional groups, and belongs to the technical field of adsorption resin. The synthesis method comprises the following steps: (1) preparing a water phase; (2) preparing an oil phase; (3) polymerization: slowly adding the oil phase into the water phase to prepare resin white balls; (4) extracting a pore-foaming agent; (5) dibromoethane grafting: adding NaH into the fully swelled resin in tetrahydrofuran, stirring at 0 DEG C until the reaction is complete, and adding 1, 2-dibromoethane for grafting reaction; and (6) amino functionalization: adding ammonia water and ethidene diamine into the resin which is fully swelled by absolute ethyl alcohol, and fully reacting to obtain amino-containing resin. The specific surface area of the synthesized resin is 450-600m < 2 > / g, the single particle strength is greater than 6N, the bilirubin at a long distance can be effectively captured, and the bilirubin adsorption capacity of the resin is 35.0-45.0 mg / g.