32 results about "Spinal dura mater" patented technology

The invention relates to an I-type medical collagen material keeping an original specific triple-helical structure of collagen, and an extraction method thereof, meninges/spinal meninges biomembrane made from the I-type medical collagen material, and a preparation process of the biomembrane, and application of the biomembrane to preparing meninges/spinal meninges tissue repair materials. The I-type medical collagen material keeping the original specific triple helix structure of collagen has the advantages of low immunogenicity, no foreign body reaction, good biocompatibility and controllabledegradation rate, the prepared meninges/spinal meninges biomembrane has certain stretching resistance strength, repairable and regenerative dura mater/spinal meninges tissue and tissue adhesion prevention/reduction, and the biomembrane is applicable to repair and regeneration of injured cerebral dura mater and spinal dura mater.

The medical collagen material is made through the processes of chondroitin sulfate crosslinking, high temperature vacuum drying and ethylene oxide. Is has stable molecule structure and better anti-seepage and anti-stick performance, and is used in repairing cerebral dura mater, spinal dura mater and peripheral nerve.

The invention discloses a micromirror spinal dura mater external cavity puncturing device, which mainly comprises a puncture needle medicine outlet, a micromirror camera, a water injection port, a thrust sensor, a water storage bag, a water injection pipe, an optic guide fiber, a syringe body, an electric control push rod, a connecting line and a micromirror computer, wherein the puncture needle medicine outlet is arranged under the water injection port, the micromirror camera is arranged in front of the puncture needle medicine outlet, the water injection port is arranged behind the micromirror camera, the thrust sensor is arranged in front of the electric control push rod, the electric control push rod is arranged under the connecting line, and the micromirror computer is arranged between the thrust sensor and the electric control push rod. The device has the advantages that the accurate puncturing process of the electric control push rod is ensured, and the accuracy of the puncturing position is improved; the manual operation is replaced by the micromirror camera, the judging accuracy is high, and the puncturing effect is improved.

The invention relates to a compound dura mater (spinal dura mater) implant which is used for repairing defected parts of implanted dura mater (spinal dura mater) and regenerating dura mater (spinal dura mater) tissue and a preparation method of the implant. A first porous layer of the implant promotes bone tissue formation as a bone conduction scaffold, a second porous layer promotes repairing andregeneration of dura mater (spinal dura mater) as a cell scaffold of regeneration collagen, and a middle layer prevents a cerebrospinal fluid from overflowing. The compound dura mater (spinal dura mater) implant can effectively promote regeneration of dura mater (spinal dura mater) and combination with bone.

The invention relates to the technical field of medical apparatuses, in particular to an electric-coagulation hemostatic device comprising a body 1 and a head 2, wherein a pair of slots 3 and 4 which are matched with a forceps blade of the common bipolar coagulation forceps is arranged in the body 1, the head 2 comprises a protecting plate 5 and a pair of tissue contact electrodes 6 and 7, wherein the pair of tissue contact electrodes 6 and 7 are fixed on the protecting plate 5, the slots 3 and 4 are respectively connected with the tissue contact electrodes 6 and 7 by metal wires 8 and 9 which are buried into the body 1 and the protecting plate 5, the body 1 and the head 2 form a certain included angle, and the protecting plate 5 and the body 1 are insulators. The protecting plate 5 is used for preventing heat generated from electric coagulation from being quickly transferred to the other side of the protecting plate from one side to destroy spinal dura mater, spinal cord and nerves. The invention has simple structure and convenience for operation, can quickly and definitely carry out electric-coagulation hemostasis on hemorrhagic spots of epidural spaces in spinal operation and increase operation safety.

The invention discloses a CT image spine and spinal dura mater automation detection method. The method is characterized by using a series of input spinal cross sections to scan a CT image and automatically carrying out detection; filtering redundant information and extracting a portion where bones are located; and automatically detecting positions of a spine and a spinal dura mater in each image. The method is convenient and fast. Extra operation is not needed and a complicated and dull processing process needed by traditional manual determination can be avoided. The method is suitable for a series of inputs. During each time of detection, a previous detection result is taken as an initial result. And searching is performed near the initial result so that a searching range is reduced and efficiency is greatly increased.

The invention relates to a depth-limiting bone cutting device and a bone cutting method thereof, and belongs to the field of medical instruments. The depth-limiting bone cutting device comprises a positioning needle, the positioning needle is in a straight circular rod shape, and the bottom of the positioning needle is pointed. The device comprises an expansion tube which is in a tube shape, and the positioning needle is matched with the interior of the expansion tube. The device comprises a sleeve, the sleeve is a thin-wall cylinder, and the inner diameter of the sleeve is matched with the outer diameter of the expansion tube. The device comprises a bone cutting tube in a circular tube shape, the bottom of the bone cutting tube is provided with annular sawteeth, the outer diameter of thebone cutting tube is matched with the inner diameter of the sleeve, and a connecting handle sleeves the upper portion of the bone cutting tube. A percutaneous endoscopic lumbar discectomy endoscope channel is quickly and safely built, operations on lesion intervertebral discs and osteophytes under percutaneous endoscopic lumbar discectomy are facilitated, articular process can be conveniently, quickly and safely cut during operations, and damage of nerve roots and spinal dura mater can be avoided and reduced during the operations.

The invention discloses a biodegradable hydrogel sealing agent. The colloid-forming time of the hydrogel is smaller than 20 seconds, the degree of swelling is 50-200%, the bursting strength is not less than 10kPa, and the in vitro degradation time is smaller than 90 days. The preparation raw materials of the hydrogel sealing agent comprise a first component namely albumin, containing nucleophilicfunctional groups, and a second compound of a hydrophilic polymer containing a plurality of electrophilic functional groups, wherein the two components are mixed physically through a dual medicine mixing machine, and in site covalent cross-linking is performed to form the hydrogel. The physical properties and the degradability of the hydrogel can be adjusted through changing the first component orthe second component, so that the biodegradable hydrogel sealing agent can be used for sealing wounded parts of different tissue parts in bodies, such as spinal dura mater damage parts.

The invention relates to a spinal dura mater sac compression detection method and device and a storage medium. The method comprises the following steps: segmenting a spine image of a to-be-detected object to obtain a segmentation result of a spinal dura mater sac in the spine image; performing center line extraction on the spinal dura mater sac to obtain a center line of the spinal dura mater sac;calculating a first distance value between at least one central point on the central line and the boundary of the spinal dura mater sac to obtain a first distance value set; and analyzing the compression condition of the spinal dura mater capsule according to the first distance value set to obtain a compression analysis result of the spinal dura mater capsule. Accuracy of the obtained spinal duramater sac compression detection result can be improved.

The invention provides a sandwich-type composite membrane support, comprising a dense outer layer, a sandwich layer and an inner layer from top to bottom, the dense outer layer is a polylactic acid film, and the sandwich layer is a mesoporous organism loaded with biologically active factors Active glass spheres, the inner layer is a chitosan membrane loaded with seed cells. In order to solve the problem that the single nerve bundle that has been damaged (but not dead) cannot be repaired and treated by the existing technology; the existing drug-loaded system cannot achieve the directional release of the drug and cannot guarantee the high concentration of the damaged local factor; most loading The drug system is easy to degrade, the drug loading is low, and the drug release cannot run through the repair process of spinal cord injury. The drug loading system is too large, which may compress the spinal cord, and is not conducive to suturing the dura mater, resulting in the formation of cerebrospinal fluid leakage.

The invention discloses a biological adhesive and a preparation method and application thereof. The biological adhesive comprises 4-arm polyethylene glycol amine and 4-arm polyethylene glycol succinimide succinate according to the mass ratio of 1: (0.1-10). The biological adhesive disclosed by the invention has the advantages of good biocompatibility, degradability and relatively high adhesive capacity, and is enough to tolerate the pressure of cerebrospinal fluid after being adhered to the spinal dura mater. Moreover, the biological adhesive disclosed by the invention is convenient to operatein an operation, can be independently used and does not need to be sutured, so that the operation time is greatly shortened and the operation risk is reduced. The biological adhesive disclosed by theinvention can be used for dura mater injuries of a special part which cannot be effectively sutured by a conventional method, such as injuries in front of and on the side of the dura mater and injuries in the positions of nerve root sleeves, can effectively reduce complications of cerebrospinal fluid leakage after a spinal operation, and improves prognosis of a patient.

The present disclosure relates to an interspinous omnidirectional dynamic stabilization device, including a first fixing part, a second fixing part, a connecting structure and an elastic structure, wherein the first fixing part and the second fixing part are fixedly connected to each other through the connecting structure and elastic structure, the bottoms of the first fixing part and the second fixing part are provided with one or more barbs, the elastic structure is made up of one or more U-shaped structures connected to each other, and the first fixing part and the second fixing part are provided with fixing holes respectively. The device is able to provide the maximum matching for the mobility in all directions, according to the requirements on the physiological activities of the human body, without causing stabilizing structures to be relatively displaced, or loosen and fall off. In addition, the device has a reasonably designed structure, with a small size. The device can be firmly fixed, and have a strong ability of elasticity attenuation resistance. In the device, the prosthesis has strong vertical support force at the bottom of the spinous process after implantation. Moreover, the device is fixed to the spinous processes and lamina, with the elastic structure attached to the spinous processes on either side of an interspinous space, and the bottom of the prosthesis is not forced to be close to the spinal dura mater, to reduce the risk of damaging the spinal dura mate during or after surgery.

The invention relates to a blunt nerve towing and protecting stripping finger, particularly to a blunt nerve towing and protecting stripping finger applied to an exploratory operation on a depressor nerve root of an orthopaedic spinal canal. The invention provides a blunt nerve towing and protecting stripping finger which is simple and reliable to operate, can effectively prevent a stripping finger from sliding to injure a nerve, improves operation safety and lightening a pain of a patient. The blunt nerve towing and protecting stripping finger comprises a handle, a top cone and a stripping film, wherein the stripping film is arranged on the top cone; the top cone is arranged below the handle; a gyration center of the handle is coincident with that of the top cone. The blunt nerve towing and protecting stripping finger provided by the application is provided with the arc-shaped stripping film to tow, obstruct and protect a nerve root and a spinal dura mater, also is provided with the relatively sharp top cone at the top end of the stripping finer, can be relatively stably fixed on a posterior longitudinal ligament behind a vertebral body, has a stable supporting point to avoid a sliding phenomenon, and can safely tow and strip the nerve root and the spinal dura mater.

The invention relates to a method for establishing a spinal dura mater leakage arachnoid hernia type sacral canal cyst model. The method comprises the following steps: step 1) selecting a model animal; 2) exposing the tail end of the dural sac in the lumbosacral vertebrae of the model animal through an operation; 3) irregularly cutting the tail end of dural sac or thick nerve sleeve adventitia; and 4) completing modeling. By means of the method, the spinal dura mater leakage arachnoid hernia type sacral canal cyst animal model with the survival rate of 100%and the modeling success rate of 60%can be simulated and the cyst form is very similar to that in real cases.

The invention relates to a moving and static stabilizer between spine plates, and belongs to the technical field of imbedded objects in human body of medical devices. The moving and static stabilizeris of an integrated structure and is formed by a first connection part, a second connection part, an engagement part, first fixed parts and second fixed parts. The first connection part and the secondconnection part are respectively arranged on two sides of the engagement part. The first fixed parts are symmetrically arranged on outer side face of the upper end of the first connection part. The second fixed parts are symmetrically arranged on the outer side face of the upper end of the second connection parts. The engagement part is of a straight plate-shaped structure. According to the invention, elastic supporting-away between spines and front and back bending of the spine can be achieved; front and back translation and left and right lateral movement between vertebra joints can be achieved; in addition, the stabilizer is not forced to be embedded to be close to the spinal dura mater, the operation time is short, the operation safety is high and the stabilizer can be used for caseswith quite small spine interval; and long-term use demands of patients are met.

The invention discloses a lumbar puncture training module which comprises a simulation outer skin, a simulation lumbar vertebra bone, simulation supraspinal ligament and simulation interspinous ligament and a simulation subcutaneous tissue, and is characterized in that a simulation ligamentum flavum and a simulation puncture tube are arranged on the simulation lumbar vertebra bone; the simulation puncture tube is arranged in an entocoele of the simulation lumbar vertebra bone, and the simulation puncture tube comprises a simulation spinal canal and a simulation spinal dura mater; the simulation ligamentum flavum is arranged in an exocoel of the simulation lumbar vertebra bone; the simulation lumbar vertebra bone is wrapped on the simulation supraspinal ligament and interspinous ligament, the simulation supraspinal ligament and interspinous ligament is wrapped in the simulation subcutaneous tissue; and the simulation subcutaneous tissue is wrapped by the simulation outer skin. The manufacturing method of the module is an integrated forming manufacturing method, the problems of needle inserting hand feeling and needle inserting accuracy during lumbar puncture training are solved, and replacement of the puncture module is facilitated.

The invention relates to a meningeal or spinal meningeal biological membrane prepared by collagen materials and a preparation method of the meningeal or spinal meningeal biological membrane, belongs to the field of biological medical materials, and mainly aims to solve the problems that currently a prepared collagen solution is low in concentration due to the fact that collagen is poor in solubility under a weak acid condition, and a collagen artificial cerebral dura mater (spinal dura mater) prepared by the collagen solution is poor in mechanical performance and body fluid leakage preventionperformance.

A surgical implant for repairing a defect. The implant has a first layer and a second layer. Each layer is flexible and planar. The first layer has an inner portion remote from a periphery, and an outer portion between the periphery and the inner portion. The second layer has an inner portion remote from a periphery, and an outer portion between the periphery and the inner portion. A bottom surface of the first layer near the inner portion thereof is connected to top surface of the second layer near the inner portion thereof so that the inner portion of the top layer is fixed relative to the inner portion of the second layer and the outer portion of the first layer is moveable relative to the outer portion of the second layer.

The device discloses a biological film adhesive force detection device and method. The device comprises a test vessel and a U-shaped pipe, test liquid is contained in the test vessel, a test film is arranged at the top of the test vessel, a defect area is arranged on the test film, and a biological film to be detected covers the defect area and seals the defect area through adhesive force betweenthe biological film to be detected and the test film; the U-shaped pipe is provided with a vertical section, the upper end of the vertical section is a liquid inlet, the other end of the vertical section is horizontally inserted into the test vessel, and the test vessel, the test film and the biological film to be detected form a sealed cavity filled with test liquid. According to the invention, asimple model is used for simulating the leakage condition of physiological liquid such as cerebrospinal fluid and the like; change of the adhesive force between the biological film to be detected andthe test film, such as the change of the adhesive force between the suture-free dura mater (spinal dura mater) patch and a biological film similar to an autologous meninx, is obtained, so that the magnitude of the adhesive force is quickly calculated, and the method has great significance in clinical application of developing biological film products with compact film layers and non-permeability.

The invention relates to a pen point type double-side-hole pure spinal anaesthesia puncture needle. The puncture needle is provided with a needle handle and a needle body. The top end of the needle body is a needle point, and two symmetrical needle holes are formed in the side wall of the top point; two symmetrical needle handle side wings are arranged on the side wall of the needle handle, the length direction of the needle handle side wings is perpendicular to the length direction of the needle body, and anti-slipping protrusions are arranged at the outer ends of the needle handle side wings and face the needle body; anti-slipping threads are arranged on the external surface of the needle handle and the external surfaces of the needle handle side wings respectively; the needle point is conical. The pen point type double-side-hole pure spinal anaesthesia puncture needle has the advantages that it can be guaranteed that cerebrospinal fluid is drawn back smoothly, and whether the needle point reaches the subarachnoid space can be judged through visually observing drawback of the cerebrospinal fluid; the force-applying direction of puncturing and the needle body are kept in the same straight line, in this way, puncturing difficulty is lowered, and the success rate of puncturing is increased; damage to the ligament and spinal dura mater is small, and the probability of pain in back and loin, headache and other complications can be effectively lowered.

The invention relates to a method for establishing a dura mater semipermeable membrane type sacral canal cyst model. The method comprises the following steps: step 1) selecting a model animal; 2) exposing the tail end of the dural sac in the lumbosacral vertebrae of the model animal through an operation; 3) slowly scraping the side wall dura mater at the tail end of the dura mater by using a cutter until the dura mater becomes semi-permeable membrane-shaped; and 4) completing modeling. By means of the method, the sacral canal cyst animal model with the survival rate of 60% or above can be simulated and the cyst form is very similar to that in real cases.